Amino acid prodrugs of acyclovir as possible antiviral agents against ocular HSV-1 infections: Interactions with the neutral and cationic amino acid transporter on the corneal epithelium

Current Eye Research

Volumn 29, Issue 2-3, 2004, Pages 153-166

  Anand, Banmeet S ^a   Katragadda, Suresh ^a   Nashed, Yasser E ^b   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b AMGEN INC   (United States)

Author keywords

Acyclovir; Cornea; Prodrug; Transporter

Indexed keywords

2 AMINOBICYCLO[2.2.1]HEPTANE 2 CARBOXYLIC ACID; ACICLOVIR; AMINO ACID TRANSPORTER; ANTIVIRUS AGENT; GAMMA GLUTAMATE ACICLOVIR; ORNITHINE; PRODRUG; TYROSINE ACICLOVIR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIVIRAL ACTIVITY; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SOLUBILITY; DRUG TRANSPORT; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; ISOTOPE LABELING; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VARICELLA ZOSTER VIRUS;

ACYCLOVIR; AMINO ACID TRANSPORT SYSTEMS; AMINO ACID TRANSPORT SYSTEMS, BASIC; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; DRUG INTERACTIONS; DRUG STABILITY; FEASIBILITY STUDIES; GLUTAMIC ACID; HERPESVIRUS 1, HUMAN; HYDROLYSIS; KERATITIS, HERPETIC; MALE; PRODRUGS; RABBITS; TYROSINE;

EID: 9344267216     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1080/02713680490504614     Document Type: Conference Paper

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