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Volumn 5, Issue 2, 2003, Pages 72-85

Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea

Author keywords

Antiviral agent; Cornea; Nucleobase; Nucleoside; SIRC; Transport

Indexed keywords

ACICLOVIR; ADENINE; DRUG CARRIER; GANCICLOVIR; IDOXURIDINE; NITROBENZYLTHIOINOSINE; NUCLEOBASE TRANSPORTER; NUCLEOSIDE ANALOG; NUCLEOSIDE TRANSPORTER; PURINE NUCLEOSIDE; PYRIMIDINE NUCLEOSIDE; SODIUM; THYMIDINE; TRIFLURIDINE; ZIDOVUDINE; 4-NITROBENZYLTHIOINOSINE; CARRIER PROTEIN; DRUG DERIVATIVE; MERCAPTOPURINE RIBOSIDE; NUCLEOSIDE; NUCLEOTIDE TRANSPORTER; TRITIUM;

EID: 55449102594     PISSN: 15221060     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps050215     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0019877456 scopus 로고
    • Superficial herpes simplex keratitis: Double-blind comparative trial of acyclovir and idoxuridine
    • [in French] 2975
    • Colin J, Tournoux A, Chastel C, Renard G. Superficial herpes simplex keratitis: double-blind comparative trial of acyclovir and idoxuridine [in French]. Nouv Presse Med. 1981;10:2969-2970, 2975.
    • (1981) Nouv. Presse. Med. , vol.10 , pp. 2969-2970
    • Colin, J.1    Tournoux, A.2    Chastel, C.3    Renard, G.4
  • 2
    • 0034530630 scopus 로고    scopus 로고
    • The treatment of herpes simplex virus epithelial keratitis
    • Wilhelmus KR. The treatment of herpes simplex virus epithelial keratitis. Trans Am Ophthalmol Soc. 2000;98:505-532.
    • (2000) Trans. Am. Ophthalmol. Soc. , vol.98 , pp. 505-532
    • Wilhelmus, K.R.1
  • 3
    • 0019947939 scopus 로고
    • Acyclovir and trifluorothymidine in herpetic keratitis: A multicentre trial
    • la Lau C, Oosterhuis JA, Versteeg J, et al. Acyclovir and trifluorothymidine in herpetic keratitis: a multicentre trial. Br J Ophthalmol. 1982;66:506-508.
    • (1982) Br. J. Ophthalmol. , vol.66 , pp. 506-508
    • la Lau, C.1    Oosterhuis, J.A.2    Versteeg, J.3
  • 4
    • 0017583874 scopus 로고
    • Double controlled comparison of IDU and trifluorothymidine in thirty-three patients with superficial herpetic keratitis
    • Laibson PR, Arentsen JJ, Mazzanti WD, Eiferman RA. Double controlled comparison of IDU and trifluorothymidine in thirty-three patients with superficial herpetic keratitis. Trans Am Ophthalmol Soc. 1977;75:316-324.
    • (1977) Trans. Am. Ophthalmol. Soc. , vol.75 , pp. 316-324
    • Laibson, P.R.1    Arentsen, J.J.2    Mazzanti, W.D.3    Eiferman, R.A.4
  • 5
    • 2442743988 scopus 로고    scopus 로고
    • ZO1 in corneal epithelium: Association to the zonula occludens and adherens junctions
    • Sugrue SP, Zieske JD. ZO1 in corneal epithelium: association to the zonula occludens and adherens junctions. Exp Eye Res. 1997;64:11-20.
    • (1997) Exp. Eye Res. , vol.64 , pp. 11-20
    • Sugrue, S.P.1    Zieske, J.D.2
  • 6
    • 0028209910 scopus 로고
    • Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues: A review
    • Kulikowski T. Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues: a review. Pharm World Sci. 1994;16:127-138.
    • (1994) Pharm. World Sci. , vol.16 , pp. 127-138
    • Kulikowski, T.1
  • 7
    • 0030606020 scopus 로고    scopus 로고
    • Nucleoside and nucleobase transport systems of mammalian cells
    • 1286
    • Griffith DA, Jarvis SM. Nucleoside and nucleobase transport systems of mammalian cells. Biochim Biophys Acta. 1996;1286:153-181.
    • (1996) Biochim. Biophys. Acta , pp. 153-181
    • Griffith, D.A.1    Jarvis, S.M.2
  • 8
    • 0028823826 scopus 로고
    • Nucleobase and nucleoside transport in mammalian cells
    • Kraupp M, Marz R. Nucleobase and nucleoside transport in mammalian cells. Wien Klin Wochenschr. 1995;107:677-680.
    • (1995) Wien Klin. Wochenschr. , vol.107 , pp. 677-680
    • Kraupp, M.1    Marz, R.2
  • 9
    • 0032846316 scopus 로고    scopus 로고
    • Involvement of multiple transporters in the oral absorption of nucleoside analogues
    • Balimane PV, Sinko PJ. Involvement of multiple transporters in the oral absorption of nucleoside analogues. Adv Drug Deliv Rev. 1999;39:183-209.
    • (1999) Adv. Drug Deliv. Rev. , vol.39 , pp. 183-209
    • Balimane, P.V.1    Sinko, P.J.2
  • 11
    • 0033136943 scopus 로고    scopus 로고
    • Nucleoside transporters: Molecular biology and implications for therapeutic development
    • Baldwin SA, Mackey JR, Cass CE, Young JD. Nucleoside transporters: molecular biology and implications for therapeutic development. Mol Med Today. 1999;5:216-224.
    • (1999) Mol. Med. Today , vol.5 , pp. 216-224
    • Baldwin, S.A.1    Mackey, J.R.2    Cass, C.E.3    Young, J.D.4
  • 12
    • 0034533226 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain
    • Kiss A, Farah K, Kim J, Garriock RJ, Drysdale TA, Hammond JR. Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain (pt 2). Biochem J. 2000;352:363-372.
    • (2000) Biochem. J. , vol.352 , Issue.PART 2 , pp. 363-372
    • Kiss, A.1    Farah, K.2    Kim, J.3    Garriock, R.J.4    Drysdale, T.A.5    Hammond, J.R.6
  • 14
    • 0027299916 scopus 로고
    • Substrate selectivity, potential sensitivity and stoichiometry of Na(+)-nucleoside transport in brush border membrane vesicles from human kidney
    • 1149
    • Gutierrez MM, Giacomini KM. Substrate selectivity, potential sensitivity and stoichiometry of Na(+)-nucleoside transport in brush border membrane vesicles from human kidney. Biochim Biophys Acta. 1993;1149:202-208.
    • (1993) Biochim. Biophys. Acta , pp. 202-208
    • Gutierrez, M.M.1    Giacomini, K.M.2
  • 15
    • 0033748178 scopus 로고    scopus 로고
    • Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters
    • Patil SD, Ngo LY, Unadkat JD. Structure-inhibitory profiles of nucleosides for the human intestinal N1 and N2 Na+-nucleoside transporters. Cancer Chemother Pharmacol. 2000;46:394-402.
    • (2000) Cancer Chemother. Pharmacol. , vol.46 , pp. 394-402
    • Patil, S.D.1    Ngo, L.Y.2    Unadkat, J.D.3
  • 16
    • 0032994908 scopus 로고    scopus 로고
    • Functional characterization of a human purine-selective, Na+-dependent nucleoside transporter (hSPNT1) in a mammalian expression system
    • Schaner ME, Wang J, Zhang L, Su SF, Gerstin KM, Giacomini KM. Functional characterization of a human purine-selective, Na+-dependent nucleoside transporter (hSPNT1) in a mammalian expression system. J Pharmacol Exp Ther. 1999;289:1487-1491.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 1487-1491
    • Schaner, M.E.1    Wang, J.2    Zhang, L.3    Su, S.F.4    Gerstin, K.M.5    Giacomini, K.M.6
  • 18
    • 0027182514 scopus 로고
    • High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1)
    • Griffith DA, Jarvis SM. High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1). J Biol Chem. 1993;268:20085-20090.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20085-20090
    • Griffith, D.A.1    Jarvis, S.M.2
  • 19
    • 0033166148 scopus 로고    scopus 로고
    • A human nucleobase transporter-like cDNA (SLC23A1): Member of a transporter family conserved from bacteria to mammals
    • Hogue DL, Ling V. A human nucleobase transporter-like cDNA (SLC23A1): member of a transporter family conserved from bacteria to mammals. Genomics. 1999;59:18-23.
    • (1999) Genomics , vol.59 , pp. 18-23
    • Hogue, D.L.1    Ling, V.2
  • 20
    • 0029119354 scopus 로고
    • Membrane transport of nucleobases: Interaction with inhibitors
    • Kraupp M, Marz R. Membrane transport of nucleobases: interaction with inhibitors. Gen Pharmacol. 1995;26:1185-1190.
    • (1995) Gen. Pharmacol. , vol.26 , pp. 1185-1190
    • Kraupp, M.1    Marz, R.2
  • 21
    • 17144435595 scopus 로고    scopus 로고
    • Molecular approaches toward identifying the gene(s) encoding mammalian Na+/nucleobase transporters
    • Shayeghi M, Jarvis SM. Molecular approaches toward identifying the gene(s) encoding mammalian Na+/nucleobase transporters. Biochem Soc Trans. 1997;25:489S.
    • (1997) Biochem. Soc. Trans. , vol.25
    • Shayeghi, M.1    Jarvis, S.M.2
  • 22
    • 0029121411 scopus 로고
    • Mechanisms of nucleobase transport in rabbit choroid plexus: Evidence for a Na(+)-dependent nucleobase transporter with broad substrate selectivity
    • Washington CB, Giacomini KM. Mechanisms of nucleobase transport in rabbit choroid plexus: evidence for a Na(+)-dependent nucleobase transporter with broad substrate selectivity. J Biol Chem. 1995;270:22816-22819.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22816-22819
    • Washington, C.B.1    Giacomini, K.M.2
  • 23
    • 0038300781 scopus 로고    scopus 로고
    • Functional expression of a sodium dependent nucleoside transporter on the rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine
    • In press
    • Majumdar S, Gunda S, Mitra AK. Functional expression of a sodium dependent nucleoside transporter on the rabbit cornea: role in corneal permeation of acyclovir and idoxuridine. Curr Eye Res. In press.
    • Curr. Eye Res.
    • Majumdar, S.1    Gunda, S.2    Mitra, A.K.3
  • 25
    • 0032970822 scopus 로고    scopus 로고
    • Permeability characteristics of novel mydriatic agents using an in vitro cell culture model that utilizes SIRC rabbit corneal cells
    • Goskonda VR, Khan MA, Hutak CM, Reddy IK. Permeability characteristics of novel mydriatic agents using an in vitro cell culture model that utilizes SIRC rabbit corneal cells. J Pharm Sci. 1999;88:180-184.
    • (1999) J. Pharm. Sci. , vol.88 , pp. 180-184
    • Goskonda, V.R.1    Khan, M.A.2    Hutak, C.M.3    Reddy, I.K.4
  • 26
    • 0033866659 scopus 로고    scopus 로고
    • Permeability of chemical delivery systems across rabbit corneal (SIRC) cell line and isolated corneas: A comparative study
    • Goskonda VR, Hill RA, Khan MA, Reddy IK. Permeability of chemical delivery systems across rabbit corneal (SIRC) cell line and isolated corneas: a comparative study. Pharm Dev Technol. 2000;5:409-416.
    • (2000) Pharm. Dev. Technol. , vol.5 , pp. 409-416
    • Goskonda, V.R.1    Hill, R.A.2    Khan, M.A.3    Reddy, I.K.4
  • 29
    • 0005995057 scopus 로고
    • Analysis of interactions between the corneal epithelium and liposomes: Qualitative and quantitative fluorescence studies of a corneal epithelial cell line
    • Pleyer U, Grammer J, Kosmidis P, Ruckert DG. Analysis of interactions between the corneal epithelium and liposomes: qualitative and quantitative fluorescence studies of a corneal epithelial cell line. Surv Ophthalmol. 1995;39(suppl 1):S3-16.
    • (1995) Surv. Ophthalmol. , vol.39 , Issue.SUPPL. 1
    • Pleyer, U.1    Grammer, J.2    Kosmidis, P.3    Ruckert, D.G.4
  • 31
    • 0034763155 scopus 로고    scopus 로고
    • Transport of acyclovir ester prodrugs through rabbit cornea and SIRC-rabbit corneal epithelial cell line
    • Tak RV, Pal D, Gao H, Dey S, Mitra AK. Transport of acyclovir ester prodrugs through rabbit cornea and SIRC-rabbit corneal epithelial cell line. J Pharm Sci. 2001;90:1505-1515.
    • (2001) J. Pharm. Sci. , vol.90 , pp. 1505-1515
    • Tak, R.V.1    Pal, D.2    Gao, H.3    Dey, S.4    Mitra, A.K.5
  • 32
    • 0037168216 scopus 로고    scopus 로고
    • Carrier-mediated uptake of L-tyrosine and its competitive inhibition by model tyrosine linked compounds in a rabbit corneal cell line (SIRC): Strategy for the design of transporter/receptor targeted prodrugs
    • Anand B, Chun Y, Jain B, Mitra AK. Carrier-mediated uptake of L-tyrosine and its competitive inhibition by model tyrosine linked compounds in a rabbit corneal cell line (SIRC): strategy for the design of transporter/receptor targeted prodrugs. Int J Pharm. 2002;247:115-125.
    • (2002) Int. J. Pharm. , vol.247 , pp. 115-125
    • Anand, B.1    Chun, Y.2    Jain, B.3    Mitra, A.K.4
  • 33
    • 0038577060 scopus 로고    scopus 로고
    • Identification and functional characterization of a Na+-independent large neutral amino acid transporter, LAT1, in human and rabbit corneal epithelium
    • In press
    • Jain-Vakkalagadda B, Dey S, Pal D, Mitra AK. Identification and functional characterization of a Na+-independent large neutral amino acid transporter, LAT1, in human and rabbit corneal epithelium. Invest Ophthalmol Vis Sci. In press.
    • Invest. Ophthalmol. Vis. Sci.
    • Jain-Vakkalagadda, B.1    Dey, S.2    Pal, D.3    Mitra, A.K.4
  • 34
    • 0027482773 scopus 로고
    • Ganciclovir transfer by human placenta and its effects on rat fetal cells
    • Henderson GI, Hu ZQ, Yang Y, et al. Ganciclovir transfer by human placenta and its effects on rat fetal cells. Am J Med Sci. 1993;306:151-156.
    • (1993) Am. J. Med. Sci. , vol.306 , pp. 151-156
    • Henderson, G.I.1    Hu, Z.Q.2    Yang, Y.3
  • 35
  • 36
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 37
    • 0008817735 scopus 로고    scopus 로고
    • Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells
    • del Santo B, Valdes R, Mata J, Felipe A, Casado FJ, Pastor-Anglada M. Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells. Hepatology. 1998;28:1504-1511.
    • (1998) Hepatology , vol.28 , pp. 1504-1511
    • del Santo, B.1    Valdes, R.2    Mata, J.3    Felipe, A.4    Casado, F.J.5    Pastor-Anglada, M.6
  • 38
    • 0034948487 scopus 로고    scopus 로고
    • Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver
    • del Santo B, Tarafa G, Felipe A, Casado FJ, Pastor-Anglada M. Developmental regulation of the concentrative nucleoside transporters CNT1 and CNT2 in rat liver. J Hepatol. 2001;34:873-880.
    • (2001) J. Hepatol. , vol.34 , pp. 873-880
    • del Santo, B.1    Tarafa, G.2    Felipe, A.3    Casado, F.J.4    Pastor-Anglada, M.5
  • 41
    • 85047685004 scopus 로고    scopus 로고
    • Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease
    • Reiman T, Clarke ML, Dabbagh L, et al. Differential expression of human equilibrative nucleoside transporter 1 (hENT1) protein in the Reed-Sternberg cells of Hodgkin's disease. Leuk Lymphoma. 2002;43:1435-1440.
    • (2002) Leuk. Lymphoma. , vol.43 , pp. 1435-1440
    • Reiman, T.1    Clarke, M.L.2    Dabbagh, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.