Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 26, 2003, Pages 15577-15582

  Chiba, Shigeru ^a,c   Takeshita, Kenichi ^d   Imai, Yoichi ^c   Kumano, Keiki ^c   Kurokawa, Mineo ^c   Masuda, Shigeo ^c   Shimizu, Kiyoshi ^c   Nakamura, Shuji ^a,e   Ruddle, Frank H ^a,b   Hirai, Hisamaru ^c  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^e HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; CYTOKINE; HOMEODOMAIN PROTEIN; PROTEIN DLX 1; SMAD PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL NUCLEUS; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; CYTOKINE PRODUCTION; EMBRYO DEVELOPMENT; GABAERGIC SYSTEM; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; HUMAN; HUMAN CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVINS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GENE LIBRARY; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; INHIBIN-BETA SUBUNITS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MOLECULAR SEQUENCE DATA; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 9144267052     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2536757100     Document Type: Article

References (44)

1. Miyazono, K., Kusanagi, K. & Inoue, H. (2001) J. Cell. Physiol. 187, 265-276.
2. Attisano, L. & Wrana, J. L. (2000) Curr. Opin. Cell. Biol. 12, 235-243.
3. Itoh, S., Itoh, F., Goumans, M. J. & Ten Dijke, P. (2000) Eur. J. Biochem. 267, 6954-6967.
4. Massague, J. (1998) Annu. Rev. Biochem. 67, 753-791.
5. Kawabata, M., Imamura, T., Inoue, H., Hanai, J., Nishihara, A., Hanyu, A., Takase, M., Ishidou, Y., Udagawa, Y., Oeda, E., et al. (1999) Ann. N.Y. Acad. Sci. 886, 73-82.
6. Shi, X., Yang, X., Chen, D., Chang, Z. & Cao, X. (1999) J. Biol. Chem. 274, 13711-13717.
7. Wotton, D., Lo, R. S., Lee, S. & Massague, J. (1999) Cell 97, 29-39.
8. Stock, D. W., Ellies, D. L., Zhao, Z., Ekker, M., Ruddle, F. H. & Weiss, K. M. (1996) Proc. Natl. Acad. Sci. USA 93, 10858-10863.
9. Price, M., Lemaistre, M., Pischetola, M., Di Lauro, R. & Duboule, D. (1991) Nature 351, 748-751.
10. Qiu, M., Bulfone, A., Ghattas, I., Meneses, J. J., Christensen, L., Sharpe, P. T., Presley, R., Pedersen, R. A. & Rubenstein, J. L. (1997) Dev. Biol. 185, 165-184.
11. Thomas, B. L., Tucker, A. S., Qui, M., Ferguson, C. A., Hardcastle, Z., Rubenstein, J. L. & Sharpe, P. T. (1997) Development 124, 4811-4818.
12. Bei, M. & Maas, R. (1998) Development 125, 4325-4333.
13. Shigetani, Y., Sugahara, F., Kawakami, Y., Murakami, Y., Hirano, S. & Kuratani, S. (2002) Science 296, 1316-1319.
14. Anderson, S. A., Eisenstat, D. D., Shi, L. & Rubenstein, J. L. (1997) Science 278, 474-476.
15. Bulfone, A., Wang, F., Hevner, R., Anderson, S., Cutforth, T., Chen, S., Meneses, J., Pedersen, R., Axel, R. & Rubenstein, J. L. (1998) Neuron 21, 1273-1282.
16. He, W., Ingraham, C., Rising, L., Goderie, S. & Temple, S. (2001) J. Neurosci. 21, 8854-8862.
17. Letinic, K., Zoncu, R. & Rakic, P. (2002) Nature 417, 645-649.
18. Huber, T. L., Zhou, Y., Mead, P. E. & Zon, L. I. (1998) Blood 92, 4128-4137.
19. Fortunel, N. O., Hatzfeld, A. & Hatzfeld, J. A. (2000) Blood 96, 2022-2036.
20. Li, F., Lu, S., Vida, L., Thomson, J. A. & Honig, G. R. (2001) Blood 98, 335-342.
21. Bhardwaj, G., Murdoch, B., Wu, D., Baker, D. P., Williams, K. P., Chadwick, K., Ling, L. E., Karanu, F. N. & Bhatia, M. (2001) Nat. Immunol. 2, 172-180.
22. Maguer-Satta, V., Bartholin, L., Jeanpierre, S., Gadoux, M., Bertrand, S., Martel, S., Magaud, J. P. & Rimokh, R. (2001) Exp. Hematol. 29, 301-308.
23. Kitamura, T., Sato, N., Arai, K. & Miyajima, A. (1991) Cell 66, 1165-1174.
24. Kitamura, K., Aota, S., Sakamoto, R., Yoshikawa, S. I. & Okazaki, K. (2000) Blood 95, 3371-3379.
25. Takebe, Y., Seiki, M., Fujisawa, J., Hoy, P., Yokota, K., Arai, K., Yoshida, M. & Arai, N. (1988) Mol. Cell. Biol. 8, 466-472.
26. Kitamura, T. (1998) Int. J. Hematol. 67, 351-359.
27. Goldman, L. A., Cutrone, E. C., Kotenko, S. V., Krause, C. D. & Langer, J. A. (1996) BioTechniques 21, 1013-1015.
28. Kurokawa, M., Mitani, K., Irie, K., Matsuyama, T., Takahashi, T., Chiba, S., Yazaki, Y., Matsumoto, K. & Hirai, H. (1998) Nature 394, 92-96.
29. Imai, Y., Kurokawa, M., Izutsu, K., Hangaishi, A., Maki, K., Ogawa, S., Chiba, S., Mitani, K. & Hirai, H. (2001) Oncogene 20, 88-96.
30. Nakamoto, T., Sakai, R., Honda, H., Ogawa, S., Ueno, H., Suzuki, T., Aizawa, S., Yazaki, Y. & Hirai, H. (1997) Mol. Cell. Biol. 17, 3884-3897.
31. Iler, N., Rowitch, D. H., Echelard, Y., McMahon, A. P. & Abate-Shen, C. (1995) Mech. Dev. 53, 87-96.
32. Chen, X., Rubock, M. J. & Whitman, M. (1996) Nature 383, 691-696.
33. Labbe, E., Silvestri, C., Hoodless, P. A., Wrana, J. L. & Attisano, L. (1998) Mol. Cell 2, 109-120.
34. Macias-Silva, M., Abdollah, S., Hoodless, P. A., Pirone, R., Attisano, L. & Wrana, J. L. (1996) Cell 87, 1215-1224.
35. Ishida, W., Hamamoto, T., Kusanagi, K., Yagi, K., Kawabata, M., Takehara, K., Sampath, T. K., Kato, M. & Miyazono, K. (2000) J. Biol. Chem. 275, 6075-6079.
36. Kitamura, T., Tange, T., Terasawa, T., Chiba, S., Kuwaki, T., Miyagawa, K., Piao, Y. F., Miyazono, K., Urabe, A. & Takaku, F. (1989) J. Cell. Physiol. 140, 323-334.
37. Zhang, H., Hu, G., Wang, H., Sciavolino, P., Iler, N., Shen, M. M. & Abate-Shen, C. (1997) Mol. Cell. Biol. 17, 2920-2932.
38. Hino, M., Tojo, A., Miyazono, K., Miura, Y., Chiba, S., Eto, Y., Shibai, H. & Takaku, F. (1989) J. Biol. Chem. 264, 10309-10314.
39. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F. & Massague, J. (1994) Nature 370, 341-347.
40. Nakamura, S., Stock, D. W., Wydner, K. L., Bollekens, J. A., Takeshita, K., Nagai, B. M., Chiba, S., Kitamura, T., Freeland, T. M., Zhao, Z., et al. (1996) Genomics 38, 314-324.
41. Shimamoto, T., Nakamura, S., Bollekens, J., Ruddle, F. H. & Takeshita, K. (1997) Proc. Natl. Acad. Sci. USA 94, 3245-3249.
42. Miyanaga, Y., Shiurba, R., Nagata, S., Pfeiffer, C. J. & Asashima, M. (1998) Dev. Genes Evol. 207, 417-426.
43. Zipori, D. & Barda-Saad, M. (2001) J. Leukocyte Biol. 69, 867-873.
44. Miyazawa, K., Shinozaki, M., Hara, T., Furuya, T. & Miyazono, K. (2002) Genes Cells 7, 1191-1204.