Species comparison and pharmacological characterization of rat and human CB 2 cannabinoid receptors

European Journal of Pharmacology

Volumn 505, Issue 1-3, 2004, Pages 1-9

  Mukherjee, Sutapa ^a   Adams, Monique ^a   Whiteaker, Kristi ^a   Daza, Anthony ^a   Kage, Karen ^a   Cassar, Steven ^a   Meyer, Michael ^a   Yao, Betty Bei ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Cannabinoid; Cannabinoid CB 2 receptor; GPCR; Pharmacology; Species selectivity

Indexed keywords

2 ARACHIDONOYLGLYCEROL; 2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 3 (1,1 DIMETHYLHEPTYL) 1 HYDROXY 9 METHOXYBENZO[C]CHROMEN 6 ONE; 3 (1,1 DIMETHYLHEPTYL) 1,9 DIHYDROXYBENZO[C]CHROMEN 6 ONE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; AM 1710; AM 1714; AM 360; ANANDAMIDE; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ANIMALS; ARACHIDONIC ACIDS; BINDING, COMPETITIVE; CALCIUM; CELL LINE; CHROMONES; CYCLIC AMP; CYCLOHEXANOLS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GLYCERIDES; HUMANS; INDOLES; MORPHOLINES; NAPHTHALENES; POLYUNSATURATED ALKAMIDES; RADIOLIGAND ASSAY; RATS; RECEPTOR, CANNABINOID, CB2; SPECIES SPECIFICITY; TRANSFECTION; TRITIUM;

EID: 8844282616     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.09.058     Document Type: Article

References (28)

1. 2 cannabinoid receptors: Pharmacology of the carbonyl and ethanolamide groups Prostaglandins. Leukot. Essent. Fatty. Acids. 59 2 1998 111 118
2. 2 cannabinoid receptor Biochim. Biophys. Acta 1576 2002 255 264
3. iα Nature 363 1993 274 276
4. P. Coward, S.D. Chan, H.G. Wada, G.M. Humphries, and B.R. Conklin Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors Anal. Biochem. 270 1999 242 248
5. L. Facci, R.D. Toso, S. Romanello, A. Buriani, S.D. Skaper, and A. Leon Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanlamide Proc. Natl. Acad. Sci. U. S. A. 92 1995 3376 3380
6. C.C. Felder, J.S. Veluz, and H.L. Williams Cannabinoid agonists stimulate both receptor and non receptor mediated signal transduction pathways in cells transfected with and expressing cannabinoid receptor clones Mol. Pharmacol. 42 1992 838 845
7. S. Galigue, S. Mary, J. Marchand, D. Dussossoy, D. Carriere, P. Carayon, M. Bouaboula, D. Shire, G. LeFur, and P. Casella Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulation Eur. J. Biochem. 232 1995 54 61
8. C.M. Gerard, C. Mollereau, G. Vassart, and M. Parmentier Molecular cloning of human cannabinoid receptor which is also expressed in testis Biochem. J. 279 1991 129 134
9. M. Glass, M. Dragunow, and R.L. Faull Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain Neuroscience 77 1997 299 318
10. 2 cannabinoid receptor J. Pharmacol. Exp. Ther. 292 2000 886 894
11. 2, a peripheral cannabinoid receptor Proc. Natl. Acad. Sci. U. S. A. 96 1999 14228 14233
12. J.F. Hess, J.A. Borkowski, T. Macneil, G.Y. Stonesifer, J. Fraher, C.D. Strader, and R.W. Ransom Differential pharmacology of cloned human and mouse B2 bradykinin receptors Mol. Pharmacol. 45 1994 1 8
13. A.C. Howlett Cannabinoid inhibition of adenylate cyclase: biochemistry and the response in neuroblastoma cell membranes Mol. Pharmacol. 27 1985 429 436
14. 2 cannabinoid receptors by AM-1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS Proc. Natl. Acad. Sci. U. S. A. 100 2003 10529 10533
15. 2 receptor J. Pharmacol. Exp.Ther. 296 2001 420 425
16. T.W. Klein, C. Newton, and H. Friedman Cannabinoid receptors and immunity Immunol. Today 19 1998 373 381
17. 2 cannabinoid receptor-mediated peripheral antinociception Pain 93 2001 239 245
18. α16 fusion product J. Biomol. Screen 7 2002 281 289
19. L.A. Matsuda, T.I. Bonner, and S.J. Lolait Localization of cannabinoid receptor mRNA in rat brain J. Comp. Neurol. 327 4 1993 535 550
20. L.A. Matsuda, S.J. Lolait, M.J. Brownstein, A.C. Young, and T.I. Bonner Structure of a cannabinoid receptor and functional expression of the cloned cDNA Nature 346 1990 561 564
21. S. Munro, K.L. Thomas, and M. Abu-Shaar Molecular characterization of peripheral receptor for cannabinoids Nature 365 1993 61 65
22. 2 cannabinoid receptors of L759633, L75656 and AM-630 British. J. Pharmacol. 126 1999 665 672
23. 2): identification of cannabinoid receptor subtype selective ligands J. Pharmacol. Exp. Ther. 278 1996 989 999
24. 1 cannabinoid receptor expression in brain regions associated with zebra finch song control Brain Res. 857 2000 151 157
25. K. Soderstrom, M. Leid, F.L. Moore, and T.F. Murray Behavioral, pharmacological, and molecular characterization of an amphibian cannabinoid receptor J. Neurochem. 75 2000 413 423
26. F. Yamaguchi, A.D. Macrae, and S. Brenner Molecular cloning of two cannabinoid type-1 like receptor genes from the puffer fish Fugu rubripes Genomics 35 1996 603 605
27. B. Yao, C.W. Hutchins, T.L. Carr, S. Cassar, J.N. Masters, Y.L. Bennani, T.L. Esbenshade, and A.A. Hancock Molecular modeling and pharmacological analysis of species-related histamine H3 receptor heterogeneity Neuropharmacology 44 2003 773 786
28. 2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain Eur. J. Neurosci. 17 2003 2750 2754