Simultaneous determination of digoxin and permeability markers in rat in situ intestinal perfusion samples by RP-HPLC

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 813, Issue 1-2, 2004, Pages 347-352

  Varma, Manthena V S ^a   Kapoor, Namita ^a   Sarkar, Mahua ^a   Panchagnula, Ramesh ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Digoxin; P glycoprotein; Permeability markers; Rat in situ permeability studies; RP HPLC

Indexed keywords

IN SITU SINGLE-PASS PERFUSION STUDIES; INTESTINAL ABSORPTION; P-GLYCOPROTEINS; PROPANOLOLS;

ABSORPTION; METHANOL; PROTEINS; SAMPLING; ULTRAVIOLET RADIATION;

LIQUID CHROMATOGRAPHY;

ACETIC ACID; ACETONITRILE; BUFFER; DIGOXIN; FUROSEMIDE; GLYCOPROTEIN P; MARKER; METHANOL; PHENOLSULFONPHTHALEIN; PROPRANOLOL DERIVATIVE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG DETERMINATION; FLOW RATE; INTESTINE ABSORPTION; INTESTINE PERFUSION; NONHUMAN; PERMEABILITY; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SAMPLING; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIGOXIN; INTESTINES; PERFUSION; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 8844280857     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.09.047     Document Type: Article

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