메뉴 건너뛰기




Volumn 54, Issue 5, 2004, Pages 921-931

Positive virological outcome after lopinavir/ritonavir salvage therapy in protease inhibitor-experienced HIV-1-infected children: A prospective cohort study

Author keywords

CD4+ T lymphocytes; HAART; Viral load

Indexed keywords

AMPRENAVIR; CHOLESTEROL; EFAVIRENZ; LOPINAVIR; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; TRIACYLGLYCEROL;

EID: 8844280062     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkh431     Document Type: Article
Times cited : (12)

References (57)
  • 1
    • 2442670578 scopus 로고    scopus 로고
    • Viral load and disease progression in infants infected with human immunodeficiency virus type 1
    • Women and Infants Transmission Study Group
    • Shearer, W. T., Quinn, T. C., LaRussa, P. et al. (1997). Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. New England Journal of Medicine 336, 1337-42.
    • (1997) New England Journal of Medicine , vol.336 , pp. 1337-1342
    • Shearer, W.T.1    Quinn, T.C.2    LaRussa, P.3
  • 2
    • 0033912755 scopus 로고    scopus 로고
    • Immunological response to combination nucleoside analogue plus protease inhibitor therapy in stable antiretroviral therapy-experienced human immunodeficiency virus-infected children
    • Borkowsky, W., Stanley, K., Douglas, S. D. et al. (2000). Immunological response to combination nucleoside analogue plus protease inhibitor therapy in stable antiretroviral therapy-experienced human immunodeficiency virus-infected children. Journal of Infectious Diseases 182, 96-103.
    • (2000) Journal of Infectious Diseases , vol.182 , pp. 96-103
    • Borkowsky, W.1    Stanley, K.2    Douglas, S.D.3
  • 3
    • 0031833173 scopus 로고    scopus 로고
    • Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus
    • Wintergerst, U., Hoffmann, F., Solder, B. et al. (1998). Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus. Pediatric Infectious Disease Journal 17 517-8.
    • (1998) Pediatric Infectious Disease Journal , vol.17 , pp. 517-518
    • Wintergerst, U.1    Hoffmann, F.2    Solder, B.3
  • 4
    • 0000027614 scopus 로고    scopus 로고
    • A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection
    • Mueller, B. U., Nelson, R. P., Jr, Sleasman, J. et al. (1998). A phase I/II study of the protease inhibitor ritonavir in children with human immunodeficiency virus infection. Journal of Infectious Diseases 177, 557-64.
    • (1998) Journal of Infectious Diseases , vol.177 , pp. 557-564
    • Mueller, B.U.1    Nelson Jr., R.P.2    Sleasman, J.3
  • 5
    • 0034632922 scopus 로고    scopus 로고
    • Combination nucleoside analog reverse transcriptase inhibitor(s) plus nevirapine, nelfinavir, or ritonavir in stable antiretroviral therapy-experienced HIV-infected children: Week 24 results of a randomized controlled trial - PACTG 377
    • Paediatric AIDS Clinical Trials Group 377 Study Team
    • Wiznia, A., Stanley, K., Krogstad, P. et al. (2000). Combination nucleoside analog reverse transcriptase inhibitor(s) plus nevirapine, nelfinavir, or ritonavir in stable antiretroviral therapy-experienced HIV-infected children: week 24 results of a randomized controlled trial - PACTG 377. Paediatric AIDS Clinical Trials Group 377 Study Team. AIDS Research and Human Retroviruses 16 1113-21.
    • (2000) AIDS Research and Human Retroviruses , vol.16 , pp. 1113-1121
    • Wiznia, A.1    Stanley, K.2    Krogstad, P.3
  • 6
    • 0030762825 scopus 로고    scopus 로고
    • Protease inhibitor therapy in children with perinatally acquired HIV infection
    • Rutstein, R. M., Feingold, A., Meislich, D. et al. (1997). Protease inhibitor therapy in children with perinatally acquired HIV infection. AIDS 11, F107-11.
    • (1997) AIDS , vol.11
    • Rutstein, R.M.1    Feingold, A.2    Meislich, D.3
  • 7
    • 2942625678 scopus 로고    scopus 로고
    • Extensive implementation of highly active antiretroviral therapy shows great effectiveness on the survival and surrogate markers in vertically HIV-infected children
    • Resino, S., Bellón, J., Resino, R. et al. (2004). Extensive implementation of highly active antiretroviral therapy shows great effectiveness on the survival and surrogate markers in vertically HIV-infected children. Clinical Infectious Diseases 38, 1605-12.
    • (2004) Clinical Infectious Diseases , vol.38 , pp. 1605-1612
    • Resino, S.1    Bellón, J.2    Resino, R.3
  • 8
    • 0242574934 scopus 로고    scopus 로고
    • Viral load and CD4+ T lymphocyte response to highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children: An observational study
    • Resino, S., Bellón, J., Gurbindo, D. et al. (2003). Viral load and CD4+ T lymphocyte response to highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children: an observational study. Clinical Infectious Diseases 37, 1216-25.
    • (2003) Clinical Infectious Diseases , vol.37 , pp. 1216-1225
    • Resino, S.1    Bellón, J.2    Gurbindo, D.3
  • 9
    • 17044454954 scopus 로고    scopus 로고
    • Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: A randomized controlled trial
    • Paediatric AIDS Clinical Trials Group 338 Study Team
    • Nachman, S. A., Stanley, K., Yogev, R. et al. (2000). Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Paediatric AIDS Clinical Trials Group 338 Study Team. Journal of the American Medical Association 283, 492-8.
    • (2000) Journal of the American Medical Association , vol.283 , pp. 492-498
    • Nachman, S.A.1    Stanley, K.2    Yogev, R.3
  • 10
    • 0033576814 scopus 로고    scopus 로고
    • Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1
    • Paediatric AIDS Clinical Trials Group 382 Team
    • Starr, S. E., Fletcher, C. V., Spector, S. A. et al. (1999). Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Paediatric AIDS Clinical Trials Group 382 Team. New England Journal of Medicine 341, 1874-81.
    • (1999) New England Journal of Medicine , vol.341 , pp. 1874-1881
    • Starr, S.E.1    Fletcher, C.V.2    Spector, S.A.3
  • 11
    • 0036020187 scopus 로고    scopus 로고
    • Efavirenz liquid formulation in human immunodeficiency virus-infected children
    • Starr, S. E., Fletcher, C. V., Spector, S. A. et al. (2002). Efavirenz liquid formulation in human immunodeficiency virus-infected children. Pediatric Infectious Disease Journal 21 659-63.
    • (2002) Pediatric Infectious Disease Journal , vol.21 , pp. 659-663
    • Starr, S.E.1    Fletcher, C.V.2    Spector, S.A.3
  • 12
    • 17344390474 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adults with HIV infection: Implications for clinical management
    • International AIDS Society - USA Panel
    • Hirsch, M. S., Conway, B., D'Aquila, R. T. et al. (1998). Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management. International AIDS Society - USA Panel. Journal of the American Medical Association 279, 1984-91.
    • (1998) Journal of the American Medical Association , vol.279 , pp. 1984-1991
    • Hirsch, M.S.1    Conway, B.2    D'Aquila, R.T.3
  • 13
    • 0037013040 scopus 로고    scopus 로고
    • Drug resistance at low viraemia in HIV-1-infected patients with antiretroviral combination therapy
    • Aleman, S., Soderbarg, K., Visco-Comandini, U. et al. (2002). Drug resistance at low viraemia in HIV-1-infected patients with antiretroviral combination therapy. AIDS 16, 1039-44.
    • (2002) AIDS , vol.16 , pp. 1039-1044
    • Aleman, S.1    Soderbarg, K.2    Visco-Comandini, U.3
  • 14
    • 17044457875 scopus 로고    scopus 로고
    • ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results
    • Murphy, R. L., Brun, S., Hicks, C. et al. (2001). ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results. AIDS 15, F1-9.
    • (2001) AIDS , vol.15
    • Murphy, R.L.1    Brun, S.2    Hicks, C.3
  • 15
    • 0036768328 scopus 로고    scopus 로고
    • Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy
    • Kempf, D. J., Isaacson, J. D., King, M. S. et al. (2002). Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy. Antiviral Therapy 7, 165-74.
    • (2002) Antiviral Therapy , vol.7 , pp. 165-174
    • Kempf, D.J.1    Isaacson, J.D.2    King, M.S.3
  • 16
    • 0037344230 scopus 로고    scopus 로고
    • Forty-eight-week evaluation of lopinavir/ritonavir, a new protease inhibitor, in human immunodeficiency virus-infected children
    • Saez-Llorens, X., Violari, A., Deetz, C. O. et al. (2003). Forty-eight-week evaluation of lopinavir/ritonavir, a new protease inhibitor, in human immunodeficiency virus-infected children. Pediatric Infectious Disease Journal 22, 216-24.
    • (2003) Pediatric Infectious Disease Journal , vol.22 , pp. 216-224
    • Saez-Llorens, X.1    Violari, A.2    Deetz, C.O.3
  • 17
    • 8844277870 scopus 로고
    • In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
    • Condra, J. H., Schleif, W. A., Blahy, O. M. et al. (1995). In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Science 268, 35.
    • (1995) Science , vol.268 , pp. 35
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 18
    • 0034909925 scopus 로고    scopus 로고
    • Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients
    • Kempf, D. J., Isaacson, J. D., King, M. S. et al. (2001). Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients. Journal of Virology 75, 7462-9.
    • (2001) Journal of Virology , vol.75 , pp. 7462-7469
    • Kempf, D.J.1    Isaacson, J.D.2    King, M.S.3
  • 19
    • 0029743820 scopus 로고    scopus 로고
    • Relationship of virological, immunological, and clinical parameters in infants with vertically acquired human immunodeficiency virus type 1 infection
    • Munoz-Fernandez, M. A., Obregon, E., Navarro, J. et al. (1996). Relationship of virological, immunological, and clinical parameters in infants with vertically acquired human immunodeficiency virus type 1 infection. Pediatric Research 40, 597-602.
    • (1996) Pediatric Research , vol.40 , pp. 597-602
    • Munoz-Fernandez, M.A.1    Obregon, E.2    Navarro, J.3
  • 20
    • 0343183245 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adult HIV-1 infection: Recommendations of an International AIDS Society - USA Panel
    • Hirsch, M. S., Brun-Vezinet, F., D'Aquila, R. T. et al. (2000). Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society - USA Panel. Journal of the American Medical Association 283, 2417-26.
    • (2000) Journal of the American Medical Association , vol.283 , pp. 2417-2426
    • Hirsch, M.S.1    Brun-Vezinet, F.2    D'Aquila, R.T.3
  • 21
    • 0032540034 scopus 로고    scopus 로고
    • Guidelines for use of antiretroviral agents in paediatric HIV infection
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention (1998). Guidelines for use of antiretroviral agents in paediatric HIV infection. Morbidity and Mortality Weekly Report 47, 1-43.
    • (1998) Morbidity and Mortality Weekly Report , vol.47 , pp. 1-43
  • 22
    • 0000771140 scopus 로고
    • Revised classification system for human immunodeficiency virus infection in children less than 13 years of age
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention (1994). Revised classification system for human immunodeficiency virus infection in children less than 13 years of age. Morbidity and Mortality Weekly Report 43, 1-10.
    • (1994) Morbidity and Mortality Weekly Report , vol.43 , pp. 1-10
  • 23
    • 0036049551 scopus 로고    scopus 로고
    • PENTA guidelines for the use of antiretroviral therapy in paediatric HIV infection
    • Paediatric European Network for Treatment of AIDS
    • Sharland, M., di Zub, G. C., Ramos, J. T. et al. (2002). PENTA guidelines for the use of antiretroviral therapy in paediatric HIV infection. Paediatric European Network for Treatment of AIDS. HIV Medicine 3, 215-26.
    • (2002) HIV Medicine , vol.3 , pp. 215-226
    • Sharland, M.1    di Zub, G.C.2    Ramos, J.T.3
  • 24
    • 0033587510 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy in a large urban clinic: Risk factors for virological failure and adverse drug reactions
    • Lucas, G. M., Chaisson, R. E. & Moore, R. D. (1999). Highly active antiretroviral therapy in a large urban clinic: risk factors for virological failure and adverse drug reactions. Annals of Internal Medicine 131, 81-7.
    • (1999) Annals of Internal Medicine , vol.131 , pp. 81-87
    • Lucas, G.M.1    Chaisson, R.E.2    Moore, R.D.3
  • 25
    • 0035951502 scopus 로고    scopus 로고
    • The use of and response to second-line protease inhibitor regimens: Results from the EuroSIDA study
    • Mocroft, A., Phillips, A. N., Miller, V. et al. (2001). The use of and response to second-line protease inhibitor regimens: results from the EuroSIDA study. AIDS 15, 201-9.
    • (2001) AIDS , vol.15 , pp. 201-209
    • Mocroft, A.1    Phillips, A.N.2    Miller, V.3
  • 26
    • 0033811217 scopus 로고    scopus 로고
    • Immunological, virological and clinical response to highly active antiretroviral therapy treatment regimens in a complete clinic population
    • Royal Free Centre for HIV Medicine
    • Mocroft, A., Devereux, H., Kinloch-de-Loes, S. et al. (2000). Immunological, virological and clinical response to highly active antiretroviral therapy treatment regimens in a complete clinic population. Royal Free Centre for HIV Medicine. AIDS 14, 1545-52.
    • (2000) AIDS , vol.14 , pp. 1545-1552
    • Mocroft, A.1    Devereux, H.2    Kinloch-de-Loes, S.3
  • 27
    • 0037103631 scopus 로고    scopus 로고
    • Treatment with lopinavir/ritonavir in heavily pretreated subjects failing multiple antiretroviral regimens in clinical practice
    • Romano, L., Peduzzi, C., Venturi, G. et al. (2002). Treatment with lopinavir/ritonavir in heavily pretreated subjects failing multiple antiretroviral regimens in clinical practice. Journal of Acquired Immune Deficiency Syndromes 30, 533-5.
    • (2002) Journal of Acquired Immune Deficiency Syndromes , vol.30 , pp. 533-535
    • Romano, L.1    Peduzzi, C.2    Venturi, G.3
  • 28
    • 0002151217 scopus 로고    scopus 로고
    • Clinical, virological and immunological responses of children with advanced human immunodeficiency virus type 1 disease treated with protease inhibitors
    • Melvin, A. J., Mohan, K. M., Arcuino, L. A. et al. (1997). Clinical, virological and immunological responses of children with advanced human immunodeficiency virus type 1 disease treated with protease inhibitors. Clinical and Experimental Immunology 110 15-21.
    • (1997) Clinical and Experimental Immunology , vol.110 , pp. 15-21
    • Melvin, A.J.1    Mohan, K.M.2    Arcuino, L.A.3
  • 29
    • 0034045783 scopus 로고    scopus 로고
    • Clinical and virological response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: A multicentre study in the Netherlands
    • On behalf of the Dutch Study Group for Children with HIV-1 infections
    • van Rossum, A. M., Niesters, H. G., Geelen, S. P. et al. (2000). Clinical and virological response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: a multicentre study in the Netherlands. On behalf of the Dutch Study Group for Children with HIV-1 infections. Journal of Pediatrics 136, 780-8.
    • (2000) Journal of Pediatrics , vol.136 , pp. 780-788
    • van Rossum, A.M.1    Niesters, H.G.2    Geelen, S.P.3
  • 30
    • 0037169269 scopus 로고    scopus 로고
    • Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viraemia
    • Deeks, S. G., Barbour, J. D., Grant, R. M. et al. (2002). Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viraemia. AIDS 16, 201-7.
    • (2002) AIDS , vol.16 , pp. 201-207
    • Deeks, S.G.1    Barbour, J.D.2    Grant, R.M.3
  • 31
    • 0036347480 scopus 로고    scopus 로고
    • Dynamics of progression markers in a non-study population of HIV-1 vertically infected infants with different antiretroviral treatments
    • Resino, S., Bellón, J. M., Gurbindo, D. et al. (2002). Dynamics of progression markers in a non-study population of HIV-1 vertically infected infants with different antiretroviral treatments. Acta Paediatrica 91, 776-82.
    • (2002) Acta Paediatrica , vol.91 , pp. 776-782
    • Resino, S.1    Bellón, J.M.2    Gurbindo, D.3
  • 32
    • 0036941025 scopus 로고    scopus 로고
    • Characterizing immune reconstitution after long-term HAART in paediatric AIDS
    • Resino, S., Correa, R., Bellon, J. et al. (2002). Characterizing immune reconstitution after long-term HAART in paediatric AIDS. AIDS Research and Human Retroviruses 18, 1395-406.
    • (2002) AIDS Research and Human Retroviruses , vol.18 , pp. 1395-1406
    • Resino, S.1    Correa, R.2    Bellon, J.3
  • 33
    • 0037084239 scopus 로고    scopus 로고
    • Immunological recovery after 3 years' antiretroviral therapy in HIV-1-infected children
    • Resino, S., Sanchez-Ramon, S., Bellon, J. M. et al. (2002). Immunological recovery after 3 years' antiretroviral therapy in HIV-1-infected children. AIDS 16, 483-6.
    • (2002) AIDS , vol.16 , pp. 483-486
    • Resino, S.1    Sanchez-Ramon, S.2    Bellon, J.M.3
  • 34
    • 0032511917 scopus 로고    scopus 로고
    • Predictors of a viral response and subsequent virological treatment failure in patients with HIV starting a protease inhibitor
    • Mocroft, A., Gill, M. J., Davidson, W. et al. (1998). Predictors of a viral response and subsequent virological treatment failure in patients with HIV starting a protease inhibitor. AIDS 12, 2161-7.
    • (1998) AIDS , vol.12 , pp. 2161-2167
    • Mocroft, A.1    Gill, M.J.2    Davidson, W.3
  • 35
    • 0344015847 scopus 로고    scopus 로고
    • Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients
    • Fatkenheuer, G., Theisen, A., Rockstroh, J. et al. (1997). Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients. AIDS 11, F113-6.
    • (1997) AIDS , vol.11
    • Fatkenheuer, G.1    Theisen, A.2    Rockstroh, J.3
  • 36
    • 0033774311 scopus 로고    scopus 로고
    • Long-term responses to treatment including ritonavir or nelfinavir in HIV-1-infected children
    • Paediatric AIDS Group of Switzerland
    • Nadal, D., Steiner, F., Cheseaux, J. J. et al. (2000). Long-term responses to treatment including ritonavir or nelfinavir in HIV-1-infected children. Paediatric AIDS Group of Switzerland. Infection 28, 287-96.
    • (2000) Infection , vol.28 , pp. 287-296
    • Nadal, D.1    Steiner, F.2    Cheseaux, J.J.3
  • 37
    • 1042300267 scopus 로고    scopus 로고
    • CD38 in CD8+ T cells predict virological failure in HIV-infected children receiving antiretroviral therapy
    • Resino, S., Bellón, J., Gurbindo, D. et al. (2004). CD38 in CD8+ T cells predict virological failure in HIV-infected children receiving antiretroviral therapy. Clinical Infectious Diseases 38, 412-7.
    • (2004) Clinical Infectious Diseases , vol.38 , pp. 412-417
    • Resino, S.1    Bellón, J.2    Gurbindo, D.3
  • 39
    • 0000226848 scopus 로고    scopus 로고
    • Effect of changing antiretroviral therapy on human immunodeficiency virus viral load: Experience with fifty-four perinatally infected children
    • Purswani, M., Johann-Liang, R., Cervia, J. et al. (1999). Effect of changing antiretroviral therapy on human immunodeficiency virus viral load: experience with fifty-four perinatally infected children. Lancet 353, 2240.
    • (1999) Lancet , vol.353 , pp. 2240
    • Purswani, M.1    Johann-Liang, R.2    Cervia, J.3
  • 40
    • 0033008399 scopus 로고    scopus 로고
    • Virological response to protease inhibitor therapy in an HIV clinic cohort
    • Staszewski, S., Miller, V., Sabin, C. et al. (1999). Virological response to protease inhibitor therapy in an HIV clinic cohort. AIDS 13, 367-73.
    • (1999) AIDS , vol.13 , pp. 367-373
    • Staszewski, S.1    Miller, V.2    Sabin, C.3
  • 42
    • 0035941398 scopus 로고    scopus 로고
    • Pharmacokinetics of amprenavir and lopinavir in combination with nevirapine in highly pretreated HIV-infected patients
    • Fatkenheuer, G., Romer, K., Kamps, R. et al. (2001). Pharmacokinetics of amprenavir and lopinavir in combination with nevirapine in highly pretreated HIV-infected patients. AIDS 15 2334-5.
    • (2001) AIDS , vol.15 , pp. 2334-2335
    • Fatkenheuer, G.1    Romer, K.2    Kamps, R.3
  • 43
    • 0037169211 scopus 로고    scopus 로고
    • Unfavourable interaction of amprenavir and lopinavir in combination with ritonavir?
    • Mauss, S., Schmutz, G. & Kuschak, D. (2002). Unfavourable interaction of amprenavir and lopinavir in combination with ritonavir? AIDS 16, 296-7.
    • (2002) AIDS , vol.16 , pp. 296-297
    • Mauss, S.1    Schmutz, G.2    Kuschak, D.3
  • 44
    • 0032511927 scopus 로고    scopus 로고
    • Treatment history and baseline viral load, but not viral tropism or CCR-5 genotype, influence prolonged antiviral efficacy of highly active antiretroviral treatment
    • Bratt, G., Karlsson, A., Leandersson, A. C. et al. (1998). Treatment history and baseline viral load, but not viral tropism or CCR-5 genotype, influence prolonged antiviral efficacy of highly active antiretroviral treatment. AIDS 12, 2193-202.
    • (1998) AIDS , vol.12 , pp. 2193-2202
    • Bratt, G.1    Karlsson, A.2    Leandersson, A.C.3
  • 45
    • 0037016424 scopus 로고    scopus 로고
    • Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen
    • Le Moing, V., Chene, G., Carrieri, M. P. et al. (2002). Predictors of virological rebound in HIV-1-infected patients initiating a protease inhibitor-containing regimen. AIDS 16, 21-9.
    • (2002) AIDS , vol.16 , pp. 21-29
    • Le Moing, V.1    Chene, G.2    Carrieri, M.P.3
  • 46
    • 1842296349 scopus 로고    scopus 로고
    • Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection
    • Mellors, J. W., Munoz, A., Giorgi, J. V. et al. (1997). Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Annals of Internal Medicine 126, 946-54.
    • (1997) Annals of Internal Medicine , vol.126 , pp. 946-954
    • Mellors, J.W.1    Munoz, A.2    Giorgi, J.V.3
  • 47
    • 0042656399 scopus 로고    scopus 로고
    • Virological success of lopinavir/ritonavir salvage regimen is affected by an increasing number of lopinavir/ritonavir-related mutations
    • Bongiovanni, M., Bini, T., Adorni, F. et al. (2003). Virological success of lopinavir/ritonavir salvage regimen is affected by an increasing number of lopinavir/ritonavir-related mutations. Antiviral Therapy 8, 209-14.
    • (2003) Antiviral Therapy , vol.8 , pp. 209-214
    • Bongiovanni, M.1    Bini, T.2    Adorni, F.3
  • 48
    • 0038298323 scopus 로고    scopus 로고
    • HIV-1 phenotypic susceptibility to lopinavir (LPV) and genotypic analysis in LPV/r-naive subjects with prior protease inhibitor experience
    • Monno, L., Saracino, A., Scudeller, L. et al. (2003). HIV-1 phenotypic susceptibility to lopinavir (LPV) and genotypic analysis in LPV/r-naive subjects with prior protease inhibitor experience. Journal of Acquired Immune Deficiency Syndromes 33, 439-47.
    • (2003) Journal of Acquired Immune Deficiency Syndromes , vol.33 , pp. 439-447
    • Monno, L.1    Saracino, A.2    Scudeller, L.3
  • 49
    • 0037012979 scopus 로고    scopus 로고
    • Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity
    • Prado, J. G., Wrin, T., Beauchaine, J. et al. (2002). Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity. AIDS 16, 1009-17.
    • (2002) AIDS , vol.16 , pp. 1009-1017
    • Prado, J.G.1    Wrin, T.2    Beauchaine, J.3
  • 50
    • 0035876409 scopus 로고    scopus 로고
    • Accumulation of lopinavir resistance-associated mutations over 3 years follow-up of patients on highly active antiretroviral therapy: Implication in salvage therapy
    • Tsuchiya, K., Matsuoka, S., Hachiya, A. et al. (2001). Accumulation of lopinavir resistance-associated mutations over 3 years follow-up of patients on highly active antiretroviral therapy: implication in salvage therapy. AIDS 15, 1183-4.
    • (2001) AIDS , vol.15 , pp. 1183-1184
    • Tsuchiya, K.1    Matsuoka, S.2    Hachiya, A.3
  • 51
    • 0036569989 scopus 로고    scopus 로고
    • Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus
    • Cooper, C. L., Parbhakar, M. A. & Angel, J. B. (2002). Hepatotoxicity associated with antiretroviral therapy containing dual versus single protease inhibitors in individuals coinfected with hepatitis C virus and human immunodeficiency virus. Clinical Infectious Diseases 34, 1259-63.
    • (2002) Clinical Infectious Diseases , vol.34 , pp. 1259-1263
    • Cooper, C.L.1    Parbhakar, M.A.2    Angel, J.B.3
  • 52
    • 0035902939 scopus 로고    scopus 로고
    • Simplification with abacavir-based triple nucleoside therapy versus continued protease inhibitor-based highly active antiretroviral therapy in HIV-1-infected patients with undetectable plasma HIV-1 RNA
    • Clumeck, N., Goebel, F., Rozenbaum, W. et al. (2001). Simplification with abacavir-based triple nucleoside therapy versus continued protease inhibitor-based highly active antiretroviral therapy in HIV-1-infected patients with undetectable plasma HIV-1 RNA. AIDS 15, 1517-26.
    • (2001) AIDS , vol.15 , pp. 1517-1526
    • Clumeck, N.1    Goebel, F.2    Rozenbaum, W.3
  • 53
    • 0034519616 scopus 로고    scopus 로고
    • Lopinavir
    • Hurst, M. & Faulds, D. (2000). Lopinavir. Drugs 60 1371-81.
    • (2000) Drugs , vol.60 , pp. 1371-1381
    • Hurst, M.1    Faulds, D.2
  • 54
    • 17044457456 scopus 로고    scopus 로고
    • Lopinavir plasma concentrations and changes in lipid levels during salvage therapy with lopinavir/ritonavir-containing regimens
    • Gutierrez, F., Padilla, S., Navarro, A. et al. (2003). Lopinavir plasma concentrations and changes in lipid levels during salvage therapy with lopinavir/ritonavir-containing regimens. Journal of Acquired Immune Deficiency Syndromes 33, 594-600.
    • (2003) Journal of Acquired Immune Deficiency Syndromes , vol.33 , pp. 594-600
    • Gutierrez, F.1    Padilla, S.2    Navarro, A.3
  • 55
    • 0034943570 scopus 로고    scopus 로고
    • Prevalence and predictive value of intermittent viremia with combination HIV therapy
    • Havlir, D. V., Bassett, R., Levitan, D. et al. (2001). Prevalence and predictive value of intermittent viremia with combination HIV therapy. Journal of the American Medical Association 286, 171-9.
    • (2001) Journal of the American Medical Association , vol.286 , pp. 171-179
    • Havlir, D.V.1    Bassett, R.2    Levitan, D.3
  • 56
    • 0032578860 scopus 로고    scopus 로고
    • Maintenance antiretroviral therapies in HIV infected patients with undetectable plasma HIV RNA after triple-drug therapy
    • AIDS Clinical Trials Group Study 343 Team
    • Havlir, D. V., Marschner, I. C., Hirsch, M. S. et al. (1998). Maintenance antiretroviral therapies in HIV infected patients with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team. New England Journal of Medicine 339 1261-8.
    • (1998) New England Journal of Medicine , vol.339 , pp. 1261-1268
    • Havlir, D.V.1    Marschner, I.C.2    Hirsch, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.