-
1
-
-
0032990266
-
Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: Antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome
-
Deeks SG, Hellmann NS, Grant RM, Parkin NT, Petropoulos CJ, Becker M, Symonds W, Chesney M & Volberding PA. Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. Journal of Infectious Diseases 1999; 179:1375-1381.
-
(1999)
Journal of Infectious Diseases
, vol.179
, pp. 1375-1381
-
-
Deeks, S.G.1
Hellmann, N.S.2
Grant, R.M.3
Parkin, N.T.4
Petropoulos, C.J.5
Becker, M.6
Symonds, W.7
Chesney, M.8
Volberding, P.A.9
-
2
-
-
0032750440
-
Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting
-
Harrigan PR, Hertogs K, Verbiest W, Pauwels R, Larder B, Kemp S, Bloor S, Yip B, Hogg R, Alexander C & Montaner JS. Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting. AIDS 1999; 13:1863-1871.
-
(1999)
AIDS
, vol.13
, pp. 1863-1871
-
-
Harrigan, P.R.1
Hertogs, K.2
Verbiest, W.3
Pauwels, R.4
Larder, B.5
Kemp, S.6
Bloor, S.7
Yip, B.8
Hogg, R.9
Alexander, C.10
Montaner, J.S.11
-
3
-
-
0032839921
-
Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
-
Piketty C, Race E, Castiel P, Belec L, Pevtavin G, Si-Mohamed A, Gonzalez-Canali G, Weiss L, Clavel F & Kazatchkine MD. Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS 1999; 13:F71-F77.
-
(1999)
AIDS
, vol.13
-
-
Piketty, C.1
Race, E.2
Castiel, P.3
Belec, L.4
Pevtavin, G.5
Si-Mohamed, A.6
Gonzalez-Canali, G.7
Weiss, L.8
Clavel, F.9
Kazatchkine, M.D.10
-
4
-
-
0033827606
-
Baseline human immunodeficiency virus type 1 phenotype, genotype, and RNA response after switching from long-term hard-capsule saquinavir to indinavir or soft-gel-capsule saquinavir in AIDS Clinical Trials Group protocol 333
-
Para MF, Glidden DV, Coombs RW, Collier AC, Condra JH, Craig C, Bassett R, Leavitt R, Snyder S, McAuliffe V & Boucher C. Baseline human immunodeficiency virus type 1 phenotype, genotype, and RNA response after switching from long-term hard-capsule saquinavir to indinavir or soft-gel-capsule saquinavir in AIDS Clinical Trials Group protocol 333. Journal of Infectious Diseases 2000; 182:733-743.
-
(2000)
Journal of Infectious Diseases
, vol.182
, pp. 733-743
-
-
Para, M.F.1
Glidden, D.V.2
Coombs, R.W.3
Collier, A.C.4
Condra, J.H.5
Craig, C.6
Bassett, R.7
Leavitt, R.8
Snyder, S.9
McAuliffe, V.10
Boucher, C.11
-
5
-
-
17544379494
-
HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort
-
Miller V, Cozzi-Lepri A, Hertogs K, Gute P, Larder B, Bloor S, Klauke S, Rabenau H, Phillips A & Staszewski S. HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort. Antiviral Therapy 2000; 5:49-55.
-
(2000)
Antiviral Therapy
, vol.5
, pp. 49-55
-
-
Miller, V.1
Cozzi-Lepri, A.2
Hertogs, K.3
Gute, P.4
Larder, B.5
Bloor, S.6
Klauke, S.7
Rabenau, H.8
Phillips, A.9
Staszewski, S.10
-
6
-
-
0344593433
-
The relation between baseline HIV drug resistance and response to antiretroviral therapy: Re-analysis of retrospective and prospective studies using a standardized data analysis plan
-
DeGruttola V, Dix L, D'Aquila R, Holder D, Phillips A, Ait-Khaled M, Baxter J, Clevenbergh P, Hammer S, Harrigan R, Katzenstein D, Lanier R, Miller M, Para M, Yerly S, Zolopa A, Murray J, Patick A, Miller V, Castillo S, Pedneault L & Mellors J. The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data analysis plan. Antiviral Therapy 2000; 5:41-48.
-
(2000)
Antiviral Therapy
, vol.5
, pp. 41-48
-
-
DeGruttola, V.1
Dix, L.2
D'Aquila, R.3
Holder, D.4
Phillips, A.5
Ait-Khaled, M.6
Baxter, J.7
Clevenbergh, P.8
Hammer, S.9
Harrigan, R.10
Katzenstein, D.11
Lanier, R.12
Miller, M.13
Para, M.14
Yerly, S.15
Zolopa, A.16
Murray, J.17
Patick, A.18
Miller, V.19
Castillo, S.20
Pedneault, L.21
Mellors, J.22
more..
-
7
-
-
0033534115
-
HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed
-
Zolopa AR, Shafer RW, Warford A, Montoya JG, Hsu P, Katzenstein D, Merigan TC & Efron B. HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed. Annals of Internal Medicine 1999; 131:813-821.
-
(1999)
Annals of Internal Medicine
, vol.131
, pp. 813-821
-
-
Zolopa, A.R.1
Shafer, R.W.2
Warford, A.3
Montoya, J.G.4
Hsu, P.5
Katzenstein, D.6
Merigan, T.C.7
Efron, B.8
-
8
-
-
0002815482
-
Genetic correlates of virological response to an indinavir-containing salvage regimen in patients with nelfinavir failure
-
Condra J, Holder JJ, Schleif WA, Bakshi K, Danovich RM, Graham DJ, Shivaprakash M, Holmes K, Saah AJ, Leavitt RY, Chodakewitz JA & Emini EA. Genetic correlates of virological response to an indinavir-containing salvage regimen in patients with nelfinavir failure. Antiviral Therapy 1999; 4:44.
-
(1999)
Antiviral Therapy
, vol.4
, pp. 44
-
-
Condra, J.1
Holder, J.J.2
Schleif, W.A.3
Bakshi, K.4
Danovich, R.M.5
Graham, D.J.6
Shivaprakash, M.7
Holmes, K.8
Saah, A.J.9
Leavitt, R.Y.10
Chodakewitz, J.A.11
Emini, E.A.12
-
9
-
-
0033920318
-
A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy
-
Baxter JD, Mayers DL, Wentworth DN, Neaton JD, Hoover ML, Winters MA, Mannheimer SB, Thompson MA, Abrams DI, Brizz BJ, Ioannidis JPA & Merigan TC. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. AIDS 2000; 14:F83-F93.
-
(2000)
AIDS
, vol.14
-
-
Baxter, J.D.1
Mayers, D.L.2
Wentworth, D.N.3
Neaton, J.D.4
Hoover, M.L.5
Winters, M.A.6
Mannheimer, S.B.7
Thompson, M.A.8
Abrams, D.I.9
Brizz, B.J.10
Ioannidis, J.P.A.11
Merigan, T.C.12
-
10
-
-
0034065841
-
Persisting long-term benefit of genotype-guided treatment for HIV-infected patients failing HAART. The Viradapt study: Week 48 follow-up
-
Clevenbergh P, Durant J, Halfon P, del Giudice P, Mondain V, Montagne N, Schapiro JM, Boucher CAB & Dellamonica P. Persisting long-term benefit of genotype-guided treatment for HIV-infected patients failing HAART. The Viradapt study: week 48 follow-up. Antiviral Therapy 2000; 5:65-70.
-
(2000)
Antiviral Therapy
, vol.5
, pp. 65-70
-
-
Clevenbergh, P.1
Durant, J.2
Halfon, P.3
Del Giudice, P.4
Mondain, V.5
Montagne, N.6
Schapiro, J.M.7
Boucher, C.A.B.8
Dellamonica, P.9
-
11
-
-
0003276336
-
Phenotypic resistance testing significantly improves response to therapy: A randomized trial (VIRA 3001)
-
San Francisco, California, 30 Jan-2 Feb Abstract 237
-
Cohen C, Hunt S, Sension M, Farthing C, Conant M, Jacobson S, Nadler J, Verbiest W, Hertogs K, Ames M, Rinehart A & Graham N. Phenotypic resistance testing significantly improves response to therapy: a randomized trial (VIRA 3001). 7th Conference on Retroviruses and Opportunistic Infections. San Francisco, California, 30 Jan-2 Feb 2000, Abstract 237.
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Cohen, C.1
Hunt, S.2
Sension, M.3
Farthing, C.4
Conant, M.5
Jacobson, S.6
Nadler, J.7
Verbiest, W.8
Hertogs, K.9
Ames, M.10
Rinehart, A.11
Graham, N.12
-
12
-
-
17044457875
-
ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results
-
Murphy RL, Brun S, Hicks C, Eron JT, Gulick R, King M, White AC, Benson C, Thompson M, Kessler HA, Hammer S, Bertz R, Hsu A, Japour A & Sun E. ABT-378/ritonavir plus stavudine and lamivudine for the treatment of antiretroviral-naive adults with HIV-1 infection: 48-week results. AIDS 2001; 15:F1-F9.
-
(2001)
AIDS
, vol.15
-
-
Murphy, R.L.1
Brun, S.2
Hicks, C.3
Eron, J.T.4
Gulick, R.5
King, M.6
White, A.C.7
Benson, C.8
Thompson, M.9
Kessler, H.A.10
Hammer, S.11
Bertz, R.12
Hsu, A.13
Japour, A.14
Sun, E.15
-
13
-
-
0036499067
-
48 Week safety and antiviral activity of lopinavir/ritonavir plus nevirapine and two nucleoside analogs in human immunodeficiency virus protease inhibitor-experienced patients
-
Benson CA, Deeks S, Brun SC, Gulick R, Eron JJ, Kessler HA, Murphy RL, Hicks C, King M, Wheeler D, Feinberg J, Stryker R, Sax P, Riddler S, Thompson M, Real K, Hsu A, Kempf D, Japour A & Sun E. 48 Week safety and antiviral activity of lopinavir/ritonavir plus nevirapine and two nucleoside analogs in human immunodeficiency virus protease inhibitor-experienced patients. Journal of Infectious Diseases 2002; 185:599-607.
-
(2002)
Journal of Infectious Diseases
, vol.185
, pp. 599-607
-
-
Benson, C.A.1
Deeks, S.2
Brun, S.C.3
Gulick, R.4
Eron, J.J.5
Kessler, H.A.6
Murphy, R.L.7
Hicks, C.8
King, M.9
Wheeler, D.10
Feinberg, J.11
Stryker, R.12
Sax, P.13
Riddler, S.14
Thompson, M.15
Real, K.16
Hsu, A.17
Kempf, D.18
Japour, A.19
Sun, E.20
more..
-
14
-
-
0032566902
-
Human serum attenuates the activity of protease inhibitors toward wildtype and mutant human immunodeficiency virus
-
Molla A, Vasavanonda S, Kumar G, Sham HL, Johnson M, Grabowski B, Denissen JF, Kohlbrenner W, Plattner JJ, Leonard JM, Norbeck DW & Kempf DJ. Human serum attenuates the activity of protease inhibitors toward wildtype and mutant human immunodeficiency virus. Virology 1998; 250:255-262.
-
(1998)
Virology
, vol.250
, pp. 255-262
-
-
Molla, A.1
Vasavanonda, S.2
Kumar, G.3
Sham, H.L.4
Johnson, M.5
Grabowski, B.6
Denissen, J.F.7
Kohlbrenner, W.8
Plattner, J.J.9
Leonard, J.M.10
Norbeck, D.W.11
Kempf, D.J.12
-
15
-
-
0034909925
-
Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients
-
Kempf DJ, Isaacson JD, King MS, Brun SC, Xu Y, Real K, Bernstein BM, Japour AJ, Sun E & Rode RA. Identification of genotypic changes in human immunodeficiency virus protease that correlate with reduced susceptibility to the protease inhibitor lopinavir among viral isolates from protease inhibitor-experienced patients. Journal of Virology 2001; 75:7462-7469.
-
(2001)
Journal of Virology
, vol.75
, pp. 7462-7469
-
-
Kempf, D.J.1
Isaacson, J.D.2
King, M.S.3
Brun, S.C.4
Xu, Y.5
Real, K.6
Bernstein, B.M.7
Japour, A.J.8
Sun, E.9
Rode, R.A.10
-
16
-
-
0034019566
-
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1
-
Petropoulos CJ, Parkin NT, Limoli KL, Lie YS, Wrin T, Huang W, Tian H, Smith D, Winslow GA, Capon DJ & Whitcomb JM. A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy 2000; 44:920-928.
-
(2000)
Antimicrobial Agents and Chemotherapy
, vol.44
, pp. 920-928
-
-
Petropoulos, C.J.1
Parkin, N.T.2
Limoli, K.L.3
Lie, Y.S.4
Wrin, T.5
Huang, W.6
Tian, H.7
Smith, D.8
Winslow, G.A.9
Capon, D.J.10
Whitcomb, J.M.11
-
17
-
-
0019065897
-
Assessing laboratory evidence for neoplastic activity
-
Mantel N. Assessing laboratory evidence for neoplastic activity. Biometrics 1980; 36:381-399.
-
(1980)
Biometrics
, vol.36
, pp. 381-399
-
-
Mantel, N.1
-
18
-
-
0022039941
-
Testing the statistical certainty of a response to increasing doses of a drug
-
Tukey JW, Ciminera JL & Heyse JF. Testing the statistical certainty of a response to increasing doses of a drug. Biometrics 1985; 41:295-301.
-
(1985)
Biometrics
, vol.41
, pp. 295-301
-
-
Tukey, J.W.1
Ciminera, J.L.2
Heyse, J.F.3
-
19
-
-
0343183245
-
Antiretroviral drug resistance testing in adult HIV-1 infection - Recommendations of an International AIDS Society-USA panel
-
Hirsch MS, Brun-Vezinet F, D'Aquila RT, Hammer SM, Johnson VA, Kuritzkes DR, Loveday C, Mellors JW, Clotet B, Conway B, Demeter LM, Vella S, Jacobsen DM & Richman DD. Antiretroviral drug resistance testing in adult HIV-1 infection - Recommendations of an International AIDS Society-USA panel. Journal of the American Medical Association 2000; 283:2417-2426.
-
(2000)
Journal of the American Medical Association
, vol.283
, pp. 2417-2426
-
-
Hirsch, M.S.1
Brun-Vezinet, F.2
D'Aquila, R.T.3
Hammer, S.M.4
Johnson, V.A.5
Kuritzkes, D.R.6
Loveday, C.7
Mellors, J.W.8
Clotet, B.9
Conway, B.10
Demeter, L.M.11
Vella, S.12
Jacobsen, D.M.13
Richman, D.D.14
-
20
-
-
0013004863
-
Effects of gender, race, age and weight on the pharmacokinetics of lopinavir after single-dose Kaletra
-
Noordwijk, the Netherlands, 2-4 April. Abstract 3.11
-
Bertz R, Lam W, Hsu A, Granneman GR & Sun E. Effects of gender, race, age and weight on the pharmacokinetics of lopinavir after single-dose Kaletra. 2nd International Workshop on Clinical Pharmacology of HIV Therapy. Noordwijk, the Netherlands, 2-4 April 2001, Abstract 3,11.
-
(2001)
2nd International Workshop on Clinical Pharmacology of HIV Therapy
-
-
Bertz, R.1
Lam, W.2
Hsu, A.3
Granneman, G.R.4
Sun, E.5
-
21
-
-
0035173814
-
Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir
-
Kakuda TN, Page LM, Anderson PL, Henry K, Schacker TW, Rhame FS, Acosta EP, Brundage RC & Fletcher CV. Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir. Antimicrobial Agents and Chemotherapy 2001; 45:236-242.
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, pp. 236-242
-
-
Kakuda, T.N.1
Page, L.M.2
Anderson, P.L.3
Henry, K.4
Schacker, T.W.5
Rhame, F.S.6
Acosta, E.P.7
Brundage, R.C.8
Fletcher, C.V.9
-
22
-
-
0033942065
-
Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy: Pharmacological data from the Viradapt Study
-
1333
-
Durant J, Clevenbergh P, Garraffo R, Halfon P, Icard S, Del Giudice P, Montagne N, Schapiro JM & Dellamonica P. Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy: pharmacological data from the Viradapt Study. AIDS 1333; 14:1333-1339.
-
AIDS
, vol.14
, pp. 1333-1339
-
-
Durant, J.1
Clevenbergh, P.2
Garraffo, R.3
Halfon, P.4
Icard, S.5
Del Giudice, P.6
Montagne, N.7
Schapiro, J.M.8
Dellamonica, P.9
-
23
-
-
0003300409
-
Response to ritonavir (RTV) intensification in indinavir (IDV) recipients is highly correlated with virtual inhibitory quotient
-
Chicago, Illinois, 4-8 February, Abstract 523
-
Kempf D, Hsu A, Jiang P, Rode R, Hertogs K, Larder B, Zolopa A, Shulman N, Havlir D, Gallant J, Race E, Boller S, Swerdlow J, Jasinsky O, Renz C & Sun E. Response to ritonavir (RTV) intensification in indinavir (IDV) recipients is highly correlated with virtual inhibitory quotient. 8th Conference on Retroviruses and Opportunistic Infections. Chicago, Illinois, 4-8 February, 2001, Abstract 523.
-
(2001)
8th Conference on Retroviruses and Opportunistic Infections
-
-
Kempf, D.1
Hsu, A.2
Jiang, P.3
Rode, R.4
Hertogs, K.5
Larder, B.6
Zolopa, A.7
Shulman, N.8
Havlir, D.9
Gallant, J.10
Race, E.11
Boller, S.12
Swerdlow, J.13
Jasinsky, O.14
Renz, C.15
Sun, E.16
-
24
-
-
0034623020
-
Tipranavir inhibits broadly protease inhibitor-resistant HIV-1 clinical samples
-
Larder BA, Hertogs K, Bloor S, van den Eynde C, DeCian W, Wang YY, Freimuth WW & Tarpley G. Tipranavir inhibits broadly protease inhibitor-resistant HIV-1 clinical samples. AIDS 2000; 14:1943-1948.
-
(2000)
AIDS
, vol.14
, pp. 1943-1948
-
-
Larder, B.A.1
Hertogs, K.2
Bloor, S.3
Van den Eynde, C.4
DeCian, W.5
Wang, Y.Y.6
Freimuth, W.W.7
Tarpley, G.8
-
25
-
-
0002425512
-
Genotypic and phenotypic analysis of a large database of patient samples reveals distinct patterns of protease inhibitor cross-resistance
-
Parkin NT, Chappey C, Maranta M, Whitehurst N & Petropoulos CJ. Genotypic and phenotypic analysis of a large database of patient samples reveals distinct patterns of protease inhibitor cross-resistance. Antiviral Therapy 2001; 6:49.
-
(2001)
Antiviral Therapy
, vol.6
, pp. 49
-
-
Parkin, N.T.1
Chappey, C.2
Maranta, M.3
Whitehurst, N.4
Petropoulos, C.J.5
-
26
-
-
0003262888
-
Kaletra vs. nelfinavir in antiretroviral-naive subjects: Week 60 comparison in a phase III, blinded, randomized clinical trial
-
Buenos Aires, Argentina, 8-11 July. Abstract 6
-
Ruane P, Mendonca J, Timerman A, Cernohous P, Bauer E, Bernstein B & Sun E. Kaletra vs. nelfinavir in antiretroviral-naive subjects: week 60 comparison in a phase III, blinded, randomized clinical trial. 1st IAS Conference on HIV Pathogenesis and Treatment. Buenos Aires, Argentina, 8-11 July 2001, Abstract 6.
-
(2001)
1st IAS Conference on HIV Pathogenesis and Treatment
-
-
Ruane, P.1
Mendonca, J.2
Timerman, A.3
Cernohous, P.4
Bauer, E.5
Bernstein, B.6
Sun, E.7
-
27
-
-
0003200829
-
Comparison of the emergence of genotypic resistance over 60 weeks of therapy with lopinavir/ritonavir (Kaletra) or nelfinavir plus d4T/3TC
-
Buenos Aires, Argentina, 8-11 July. Abstract 129
-
Kempf D, Bernstein B, King M, Cernohous P, Moseley J, Gu K, Bauer E & Sun E. Comparison of the emergence of genotypic resistance over 60 weeks of therapy with lopinavir/ritonavir (Kaletra) or nelfinavir plus d4T/3TC. 1st IAS Conference on HIV Pathogenesis and Treatment. Buenos Aires, Argentina, 8-11 July 2001, Abstract 129.
-
(2001)
1st IAS Conference on HIV Pathogenesis and Treatment
-
-
Kempf, D.1
Bernstein, B.2
King, M.3
Cernohous, P.4
Moseley, J.5
Gu, K.6
Bauer, E.7
Sun, E.8
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