A novel procedure for generating both nitric oxide and superoxide in situ from chemical sources at any chosen mole ratio. First application: Tyrosine oxidation and a comparison with preformed peroxynitrite

Chemical Research in Toxicology

Volumn 13, Issue 12, 2000, Pages 1287-1293

  Hodges, George R ^a   Marwaha, Jasvir ^a   Paul, Thomas ^a   Ingold, K U ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICAL; NITRIC OXIDE; PEROXYNITRITE; SUPEROXIDE; TYROSINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION KINETICS; OXIDATION; REACTION ANALYSIS; SYNTHESIS;

MOLSIDOMINE; NITRATES; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGEN OXIDES; OXIDANTS; OXIDATION-REDUCTION; SPERMINE; SUPEROXIDES; TYROSINE;

EID: 0034487279     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0001272     Document Type: Article

References (2)

1. Mahoney, L. R. (1970) Evidence for the formation of hydroxyl radicals in the isomerisation of peroxynitrous acid to nitric acid in aqueous solution. J. Am. Chem. Soc. 92, 5262-5263.
2. Gatti, R. M., Alvarez, B., Vasquez-Vivar, J., Radi, R., and Augusto, O. (1998) Formation of spin adducts during the decomposition of peroxynitrite. Arch. Biochem. Biophys. 349, 36-46.