Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY 1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 24, 2004, Pages 5975-5978

  Luo, Guanglin ^a   Mattson, Gail K ^a   Bruce, Marc A ^a   Wong, Henry ^a   Murphy, Brian J ^a   Longhi, Daniel ^a   Antal Zimanyi, Ildiko ^a   Poindexter, Graham S ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Bioisostere; N arylpiperazine; NPY 1 receptor antagonists

Indexed keywords

AMINE; DIHYDROPYRIDINE DERIVATIVE; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; PIPERAZINE DERIVATIVE; PIPERIDONE DERIVATIVE; ZINC CHLORIDE;

AMINATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION;

BIOMIMETIC MATERIALS; CHLORIDES; DIHYDROPYRIDINES; DRUG EVALUATION, PRECLINICAL; MOLECULAR STRUCTURE; PIPERAZINES; PIPERIDINES; RECEPTORS, NEUROPEPTIDE Y; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC COMPOUNDS;

EID: 8844244875     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.10.005     Document Type: Article

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