Constitutive expression and alternative splicing of the exons encoding SCRs in Sp152, the sea urchin homologue of complement factor B. Implications on the evolution of the Bf/C2 gene family

Immunogenetics

Volumn 56, Issue 7, 2004, Pages 531-543

  Terwilliger, David P ^a   Clow, Lori A ^b,d   Gross, Paul S ^c   Smith, L Courtney ^a,b  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d United States Patent and Trademark Office   (United States)

Author keywords

Complement; Echinoderm; Evolution; Sp152; SpBf

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; AMINO ACID; LIPOPOLYSACCHARIDE; SEA WATER;

ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EVOLUTION; EXON; GENE DELETION; GENE DUPLICATION; GENETIC CODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA SPLICING; SEA URCHIN;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; COMPLEMENT C2; COMPLEMENT FACTOR B; CONSENSUS SEQUENCE; EVOLUTION; EXONS; GLYCOPROTEINS; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; REPETITIVE SEQUENCES, AMINO ACID; SEQUENCE HOMOLOGY, AMINO ACID; STRONGYLOCENTROTUS PURPURATUS;

ANIMALIA; ECHINODERMATA; ECHINOIDEA; STRONGYLOCENTROTUS; STRONGYLOCENTROTUS PURPURATUS; SUGARCANE RAMU STUNT DISEASE PHYTOPLASMA; VERTEBRATA;

EID: 8744312586     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-004-0711-0     Document Type: Article

References (73)

1. Al-Sharif WZ, Sunyer JO, Lambris JD, Smith LC (1998) Sea urchin coelomocytes specifically express a homologue of the complement component C3. J Immunol 160:2983-2997
2. Azumi K, De Santis R, De Tomaso A, Rigoutsos I, Yoshizaki F, Pinto MR, Marino R, Shida K, Ikeda M, Ikeda M, Arai M, Inoue Y, Shimizu T, Satoh N, Rokhsar DS, Du Pasquier L, Kasahara M, Satake M, Nonaka M (2003) Genomic analysis of immunity in a urochordate and the emergence of the vertebrate immune system: "waiting for Godot". Immunogenetics 55:570-581
3. Baumann H (1989) Hepatic acute phase reaction in vivo and in vitro. In Vitro Cell Dev Biol 25:115-126
4. Baumann H, Gauldie J (1994) The acute phase response. Immunol Today 15:74-80
5. Botto M, Lissandrini D, Sorio C, Walport MJ (1992) Biosynthesis and secretion of complement component (C3) by activated human polymorphonuclear leukocytes. J Immunol 149:1348-1355
6. Burset M, Seledtsov IA, Solovyev VV (2000) Analysis of canonical and non-canonical splice sites in mammalian genomes. Nucl Acids Res 28:4364-4375
7. Cheng J, Volanakis JE (1994) Alternatively spliced transcripts of the human complement C2 gene. J Immunol 152:1774-1782
8. Clow LA, Gross PS, Shih C-S, Smith LC (2000) Expression of SpC3, the sea urchin complement component, in response to lipopolysaccharide. Immunogenetics 51:1021-1033
9. Clow LA, Raftos DA, Gross PS, Smith LC (2004) The sea urchin complement homologue, SpC3, functions as an opsonin. J Exp Biol 207:2147-2155
10. Coffaro KA, Hinegardner RT (1977) Immune response in the sea urchin Lytechinus pictus. Science 197:1389-1390
11. Cole FS, Auerbach HS, Goldberger G, Colten HR (1985) Tissue-specific pretranslational regulation of complement production in human mononuclear phagocytes. J Immunol 134:2610-2616
12. Colten HR (1984) Expression of the MHC class III genes. Philos Trans R Soc Lond B Biol Sci 306:355-366
13. Colten HR (1992) Tissue-specific regulation of inflammation. J Appl Physiol 72:1-7
14. Colten HR, Strunk RC, Perlmutter DH, Cole FS (1986) Regulation of complement protein biosynthesis in mononuclear phagocytes. Ciba Found Symp 118:141-154
15. Fedorova L, Fedorov A (2003) Introns in gene evolution. Genetica 118:123-131
16. Friese MA, Hellwage J, Jokiranta TS, Meri S, Peter HH, Eibel H, Zipfel PF (1999) FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated. Mol Immunol 36:809-818
17. Ganter U, Bauer J, Majello B, Gerok W, Ciliberto G (1989) Characterization of mononuclear-phagocyte terminal maturation by mRNA phenotyping using a set of cloned cDNA probes. Eur J Biochem 185:291-296
18. Garnier G, Circolo A, Colten HR (1996) Constitutive expression of murine complement factor B gene is regulated by the interaction of its upstream promoter with hepatocytes nuclear factor 4. J Biol Chem 271:30205-30211
19. Geserick G, Patzelt D, Schroder H, Nagai T (1983) Isoelectrofocusing in the study of the Bf system: existence of two common subtypes of the BfF allele. Vox Sang 44:178-182
20. Gongora R, Figueroa F, Klein J (1998) Independent duplications of Bf and C3 complement genes in the zebrafish. Scand J Immunol 48:651-658
21. Gross PS, Al-Sharif WZ, Clow LA, Smith LC (1999) Echinoderm immunity and the evolution of the complement system. Dev Comp Immunol 23:429-442
22. Gross PS, Clow LA, Smith LC (2000) SpC3, the complement homologue from the purple sea urchin, Strongylocentrotus purpuratus, is expressed in two subpopulations of the phagocytic coelomocytes. Immunogenetics 51:1034-1044
23. Hall TA (1999) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser 41:95-98
24. Hildemann WH, Dix TG (1972) Transplantation reactions of tropical Australian echinoderms. Transplantation 14:624-633
25. Hourcade DE, Wagner LM, Oglesby TJ (1995) Analysis of the short consensus repeats of human complement factor B by site-directed mutagenesis. J Biol Chem 270:19716-19722
26. Huang Y, Krein PM, Muruve DA, Winston BW (2002) Complement factor B gene regulation: synergistic effects of TNF-α and IFN-γ in macrophages. J Immunol 169:2627-2635
27. Ishikawa N, Nonaka M, Wetsel RA, Colten HR (1990) Murine complement C2 and factor B genomic and cDNA cloning reveals different mechanisms for multiple transcripts of C2 and B. J Biol Chem 265:19040-19046
28. Jiang S-L, Samols D, Rzewnicki D, McIntyre SS, Greber I, Sipe J, Kushner I (1995) Kinetic modeling and mathematical analysis indicate that acute phase gene expression in Hep 3B cells is regulated by both transcriptional and posttranscriptional mechanisms. J Clin Invest 95:1253-1261
29. Johnson PT (1969) The coelomic elements of sea urchins (Strongylocentrotus). 3. In vitro reaction to bacteria. J Invertebr Pathol 13:42-62
30. Karp RD, Hildemann WH (1976) Specific allograft reactivity in the sea star Dermasterias imbricata. Transplantation 22:434-439
31. Kato Y, Salter-Cid L, Flajnik MF, Namikawa C, Sasaki M, Nonaka M (1995) Duplication of the MHC-linked Xenopus complement factor B gene. Immunogenetics 42:196-203
32. Katz Y, Cole FS, Strunk RC (1988) Synergism between gamma interferon and lipopolysaccharide for synthesis of factor B, but not C2, in human fibroblasts. J Exp Med 167:1-14
33. Krushkal J, Bat O, Gigli I (2000) Evolutionary relationships among proteins encoded by the regulator of complement activation gene cluster. Mol Biol Evol 17:1718-1730
34. Lee JJ, Shott RJ, Rose SJ, Thomas TL, Britten RJ, Davidson EH (1984) Sea urchin actin gene subtypes; gene number, linkage and evolution. J Mol Biol 172:149-176
35. Lévi-Strauss M, Mallat M (1987) Primary cultures of murine astrocytes produce C3 and factor B, two components of the alternative pathway of complement activation. J Immunol 139:2361-2366
36. Matsushita M, Okada H (1989) Two forms of guinea pig factor B of the alternative pathway with different molecular weights. Mol Immunol 26:669-676
37. Minta JO (1988) Synthesis of complement factor B by the human monocytes U-937 cell line. Augmentation by immunostimulatory agents. J Immunol 141:1636-1641
38. Miyama A, Kawamoto Y, Ichikawa H, Okamoto K, Hara S, Inoue T (1980) Complement proteins and macrophages. II. The secretion of factor B by lipopolysaccharide-stimulated macrophages. Microbiol Immunol 24:1223-1232
39. Multerer KA, Smith LC (2004) Two cDNAs from the purple sea urchin, Strongylocentrotus purpuratus, with multiple domains found in factor H, factor I, and complement components C6 and C7. Immunogenetics 56:89-106
40. Nakao M, Fushitani Y, Fujiki K, Nonaka M, Yano T (1998) Two diverged complement factor B/C2-like cDNA sequences from a teleost, the common carp (Cyprinus carpio). J Immunol 161:4811-4818
41. Nakao M, Matsumoto M, Nakazawa M, Fujiki K, Yano T (2002) Diversity of complement factor B/C2 in the common carp (Cyprinus carpio): three isotypes of B/C2-A expressed in different tissues. Dev Comp Immunol 26:533-541
42. Nonaka M, Ishikawa N, Passwell J, Natsuume-Sakai S, Colten HR (1989) Tissue-specific initiation of murine complement factor B mRNA transcription. J Immunol 142:1377-1382
43. Pancer Z (2000) Dynamic expression of multiple scavenger receptor cysteine-rich genes in coelomocytes of the purple sea urchin. Proc Natl Acad Sci USA 97:13156-13161
44. Pancer Z, Rast JP, Davidson EH (1999) Origins of immunity: transcription factors and homologues of effector genes of the vertebrate immune system expressed in sea urchin coelomocytes. Immunogenetics 49:773-786
45. Pasch MC, Van Den Bosch NH, Daha MR, Bos JD, Asghar SS (2000) Synthesis of complement components C3 and factor B in human keratinocytes is differentially regulated by cytokines. J Invest Dermatol 114:78-82
46. Patthy L (1999) Genome evolution and the evolution of exon-shuffling - a review. Gene 238:103-114
47. Patthy L (2003) Modular assembly of genes and the evolution of new functions. Genetica 118:217-231
48. Peelman LJ, Van de Wegh AR, Coppieters WR, Van Zeveren AJ, Bouquet YH (1991) Cloning and sequencing of the porcine complement factor B. Immunogenetics 34:192-195
49. Rast JP, Pancer Z, Davidson EH (2000) New approaches towards an understanding of deuterostomes immunity. In: Du Pasquier L, Litman GW (eds) Origin and evolution of the vertebrate immune system. Springer, Berlin Heidelberg New York, pp 3-16
50. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor
51. Shah M, Brown KM, Smith LC (2003) The gene encoding the sea urchin complement protein, SpC3, is expressed in embryos and can be upregulated by bacteria. Dev Comp Immunol 27:529-538
52. Smith CW, Patton JG, Nadal-Ginard B (1989) Alternative splicing in the control of gene expression. Annu Rev Genet 23:527-577
53. Smith LC (2001) The complement system in sea urchins. In: Beck G, Sugumaran M, Cooper E (eds) Phylogenetic perspectives on the vertebrate immune systems. Advances in experimental medicine and biology, vol 484. Kluwer/Plenum, New York, pp 363-372
54. Smith LC (2002) Thioester function is conserved in SpC3, the sea urchin homologue of the complement component C3. Dev Comp Immunol 26:603-614
55. Smith LC and Davidson EH (1992) The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes. Immunol Today 13:356-362
56. Smith LC, Britten RJ, Davidson EH (1995) Lipopolysaccharide activates the sea urchin immune system. Dev Comp Immunol 19:217-224
57. Smith LC, Chang L, Britten RJ, Davidson EH (1996) Sea urchin genes expressed in activated coelomocytes are identified by expressed sequence tags. Complement homologues and other putative immune response genes suggest immune system homology within the deuterostomes. J Immunol 156:593-602
58. Smith LC, Shih C-S, Dachenhausen SG (1998) Coelomocytes express SpBf, a homologue of factor B, the second component in the sea urchin complement system. J Immunol 161:6784-6793
59. Smith LC, Azumi K, Nonaka M (1999) Complement systems in invertebrates. The ancient alternative and lectin pathways. Immunopharmacology 42:107-120
60. Smith LC, Clow LA, Terwilliger DP (2001) The ancestral complement system in sea urchins. Immunol Rev 180:16-34
61. Smith SL (1998) Shark complement: an assessment. Immunol Rev 166:67-78
62. Strunk RC, Whitehead AS, Cole FS (1985a) Pretranslational regulation of the synthesis of the third component of complement in human mononuclear phagocytes by the lipid A portion of lipopolysaccharide. J Clin Invest 76:985-990
63. Strunk RC, Cole FS, Perlmutter DH, Colten HR (1985b) Gamma-interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genes. J Biol Chem 260:15280-15285
64. Sumiyoshi K, Andoh A, Fujiyama Y, Sakumoto H, Bamba T (1997) Biosynthesis and secretion of MHC class III gene products (complement C4 and factor B) in the exocrine pancreas. J Gastroenterol 32:367-373
65. Sundsmo JS, Chin JR, Papin RA, Fair DS, Werb Z (1985) Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. J Exp Med 161:306-322
66. Sunyer JO, Zarkadis I, Sarrias MR, Hansen JD, Lambris JD (1998) Cloning, structure, and function of two rainbow trout Bf molecules. J Immunol 161:4106-4114
67. Sutton MB, Strunk RC, Cole FS (1986) Regulation of the synthesis of the third component of complement and factor B in cord blood monocytes by lipopolysaccharide. J Immunol 136:1366-1372
68. Thomas A, Gasque P, Vaudry D, Gonzalez B, Fontaine M (2000) Expression of a complete and functional complement system by human neuronal cells in vitro. Int Immunol 12:1015-1023
69. Volanakis JE (1998) Overview of the complement system. In: Volanakis JE, Frand MM (eds) The human complement system in health and disease. Immunol Med 20:9-32
70. Weiler JM (1993) Introduction. In: Whaley K, Loos M, Weiler JM (eds) Complement in health and disease. Kluwer, Lancaster, pp 1-37
71. Whitehead AS, Sackstein R (1985) Molecular biology of the human and mouse MHC class III genes: phylogenetic conservation, genetics and regulation of expression. Immunol Rev 87:185-208
72. Wu LC, Morley BJ, Campbell RD (1987) Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5′-flanking elements. Cell 48:331-342
73. Zipfel PF, Skerka C (1999) FHL-1/reconectin: a human complement and immune regulator with cell-adhesive function. Immunol Today 20:135-140