Autocrine transforming growth factor α regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells

Journal of Biological Chemistry

Volumn 279, Issue 45, 2004, Pages 47379-47390

  Sawhney, Rajinder S ^a   Cookson, Michelle M ^a   Sharma, Bhavya ^a   Hauser, Jennie ^a   Brattain, Michael G ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; PROTEINS; TUMORS;

BASAL EXPRESSION; CONSTITUTIVE ACTIVATION; GROWTH FACTORS; PHOSPHORYLATION;

CELLS;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA2 INTEGRIN; BISINDOLYLMALEIMIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; RAPAMYCIN; S6 KINASE; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; AUTOCRINE EFFECT; CANCER CELL; CELL ADHESION; CELL MOTILITY; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AUTOCRINE COMMUNICATION; BINDING SITES; BIOTINYLATION; BLOTTING, WESTERN; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GENES, DOMINANT; HUMANS; IMMUNOBLOTTING; INDOLES; INTEGRIN ALPHA2; MALEIMIDES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTATION; PHOSPHORYLATION; PLASMIDS; PROTEIN KINASE C; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SERINE; SIGNAL TRANSDUCTION; SIROLIMUS; THREONINE; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR ALPHA;

MAMMALIA;

EID: 8744304971     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402031200     Document Type: Article

References (35)

1. Hanks, S. K., Quinn, A. M., and Hunter, T. (1988) Science 241, 42-52
2. Nemenoff, R. A., Price, D. J., Mendelsohn, M. J., Carter, E. A., and Avruch, J. (1988) J. Biol. Chem. 263, 19455-19460
3. Proud, C. G. (1996) Trends Biochem. Sci. 21, 181-185
4. Pullen, N., and Thomas, G. (1997) FEBS Lett. 410, 78-82
5. Volarevic, S., and Thomas, G. (2001) Prog. Nucleic Acid Res. Mol. Biol. 65, 101-127
6. Kawasome, H., Papst, P., Webb, S., Keller, G. M., Johnson, G. L., and Gefland, E. W. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 5033-5038
7. Shima, H., Pende, M., Chen, Y., Fumagalli, S., Thomas, G., and Kozma, S. C. (1998) EMBO J., 17, 6649-6659
8. Harada, H., Andersen, J. S., Mann, M., Terada, N., and Korsmeyer, S. J. (2001) Proc. Natl. Acad. Sci. 98, 9666-9670
9. Balasubramanian, S., and Kuppuswamy, D. (2003) J. Biol. Chem. 278, 42214-42224
10. Juliano, R. L. (2002) Annu. Rev. Pharmacol. Toxicol. 42, 283-323
11. Klekotka, P. A., Santoro, S. A., and Zutter, M. M. (2001) J. Biol. Chem. 276, 9503-9511
12. Zutter, M., and Santoro, S. (1990) Am. J. Pathol. 137, 113-120
13. Yang, C., Zeisberg, M., Lively, J. C., Nyberg, P., Afdhal, N., and Kalluri, R. (2003) Cancer Res. 63, 8312-8317
14. Paine, E., Palmantier, R., Akiyama, S. K., Olden, K., and Roberts, J. D. (2000) J. Biol. Chem. 275, 11284-11290
15. Zutter, M. M., Santoro, S.A., Staatz, W. D., and Tsung, Y. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7411-7415
16. Chan, B. M. C., Matsuura, N., Takada, Y., Zetter, B. R., and Hemler, M. E. (1991) Science 251, 1600-1602
17. Sawhney, R. S., Zhou, G.-H. K, Humphrey, L. E., Ghosh, P., Kreisberg, J. I., and Brattain, M. G. (2002) J. Biol. Chem. 277, 75-86
18. Sawhney, R. S., Sharma, B., Humphrey, L. E., and Brattain, M. G. (2003) J. Biol. Chem. 278, 19861-19869
19. Romanelli, A., Dreisbach, V. C., and Blenis, J. (2002) J. Biol. Chem. 277, 40281-40289
20. Cheatham, L., Monfar, M., Chou, M. M., and Blenis, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11696-11700
21. Pearson, R. B., Dennis, P. B., Han, J., Williamson, N. A., Kozma, S. C., Wettenhall, R. E. H., and Thomas, G. (1995) EMBO 14, 5279-5287
22. Saitoh, M., Pullen, N., Brennan, P., Cantrell, D., Dennis, P. B., and Thomas, G. (2002) J. Biol. Chem. 277, 20104-20112
23. Giaever, I., and Keese, C. R. (1993) Nature 368, 591-592
24. Giaever, I., and Keese, C. R. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7896-7900
25. Giaever, I., and Keese, C. R. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 3761-3764
26. Lehman, J. A., Calvo, V., and Gomez-Cambronero, J. (2003) J. Biol. Chem. 278, 28130-28138
27. Toullec, D., Pianetti, P., Coste, H., Bellevergue, P., Grand-Perret, T., Ajakane, M., Baudet, V., Boissin P., Boursier, E., Loriolle, F., Duhamel, L., Charon, D., and Kirilovsky, J. (1991) J. Biol. Chem. 286, 15771-15781
28. Keese, C. R., Bhawe, K., Wegener, J., and Giaver, I. (2002) BioTechniques 33, 842-850
29. Fukazawa, H., and Uehara, Y. (2000) Cancer Res. 60, 2104-2107
30. Ray, L. B., and Sturgill, T. W. (1988) J. Biol. Chem. 263, 12721-12727
31. Pellegatta, F., Chierchia, S. L., and Zocci, M. R. (1998) J. Biol. Chem., 273, 27768-27771
32. Lindberg, L. E., Hedjazifar, S., and Baeckstrom, D. (2002) Mol. Biol. Cell 13, 2894-2908
33. Pardo, O. E., Arcaro, A., Salerno, G., Tetley, T. D., Valovka, T., Gout, I., and Seckl, M. J. (2001) Oncogene 20, 7658-7667
34. Fang, Y., Vilella-Bach, M., Bachmann, R., Flanigan, A., and Chen, J. (2001) Science 294, 1942-1945
35. Fingar, D. C., and Blenis, J. (2004) Oncogene 23, 3151-3171