메뉴 건너뛰기




Volumn 70, Issue 11, 2004, Pages 6518-6524

Aflatoxin biosynthesis cluster gene cypA is required for G aflatoxin formation

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; FUNGI; GENES; TOXIC MATERIALS;

EID: 8744255615     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.70.11.6518-6524.2004     Document Type: Article
Times cited : (157)

References (39)
  • 1
    • 0000703962 scopus 로고
    • Improved media for selecting nitrate-nonutilizing mutants in Aspergillus flavus
    • Bayman, P., and P. J. Cotty. 1991. Improved media for selecting nitrate-nonutilizing mutants in Aspergillus flavus. Mycologia 83:311-316.
    • (1991) Mycologia , vol.83 , pp. 311-316
    • Bayman, P.1    Cotty, P.J.2
  • 2
    • 0025728119 scopus 로고
    • Enzymological evidence for separate pathways for aflatoxin B1 and B2 biosynthesis
    • Bhatnagar, D., T. E. Cleveland, and D. G. Kingston. 1991. Enzymological evidence for separate pathways for aflatoxin B1 and B2 biosynthesis. Biochemistry 30:4343-4350.
    • (1991) Biochemistry , vol.30 , pp. 4343-4350
    • Bhatnagar, D.1    Cleveland, T.E.2    Kingston, D.G.3
  • 4
    • 0000286404 scopus 로고
    • Oxidation-reduction reactions in biosynthesis of secondary metabolites
    • D. Bhatnagar, E. B. Lillehoj, and D. K. Arora (ed.), Marcel Dekker, New York, N.Y.
    • Bhatnagar, D., K. C. Ehrlich, and T. E. Cleveland. 1992. Oxidation-reduction reactions in biosynthesis of secondary metabolites, p. 255-285. In D. Bhatnagar, E. B. Lillehoj, and D. K. Arora (ed.), Mycotoxins in ecological systems, vol. 10. Marcel Dekker, New York, N.Y.
    • (1992) Mycotoxins in Ecological Systems , vol.10 , pp. 255-285
    • Bhatnagar, D.1    Ehrlich, K.C.2    Cleveland, T.E.3
  • 5
    • 0037135196 scopus 로고    scopus 로고
    • Molecular and functional characterization of a second copy of the aflatoxin regulatory gene, aflR-2, from Aspergillus parasiticus
    • Cary, J. W., J. M. Dyer, K. C. Ehrlich, M. S. Wright, S.-H. Liang, and J. E. Linz. 2002. Molecular and functional characterization of a second copy of the aflatoxin regulatory gene, aflR-2, from Aspergillus parasiticus. Biochim. Biophys. Acta 1576:316-323.
    • (2002) Biochim. Biophys. Acta , vol.1576 , pp. 316-323
    • Cary, J.W.1    Dyer, J.M.2    Ehrlich, K.C.3    Wright, M.S.4    Liang, S.-H.5    Linz, J.E.6
  • 6
    • 0030068488 scopus 로고    scopus 로고
    • Molecular characterization of an Aspergillus parasiticus gene, norA, located on the aflatoxin biosynthesis gene cluster
    • Cary, J. W., M. Wright, D. Bhatnagar, R. Lee, and F. S. Chu. 1996. Molecular characterization of an Aspergillus parasiticus gene, norA, located on the aflatoxin biosynthesis gene cluster. Appl. Environ. Microbiol. 62:360-366.
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 360-366
    • Cary, J.W.1    Wright, M.2    Bhatnagar, D.3    Lee, R.4    Chu, F.S.5
  • 9
    • 0029079145 scopus 로고
    • Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis
    • Chang, P.-K., K. C. Ehrlich, J. Yu, D. Bhatnagar, and T. E. Cleveland. 1995. Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis. Appl. Environ. Microbiol. 61:2372-2377.
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 2372-2377
    • Chang, P.-K.1    Ehrlich, K.C.2    Yu, J.3    Bhatnagar, D.4    Cleveland, T.E.5
  • 10
    • 0028385285 scopus 로고
    • Comparison of four media for the isolation of Aspergillus flavus group fungi
    • Cotty, P. J. 1994. Comparison of four media for the isolation of Aspergillus flavus group fungi. Mycopathologia 125:157-162.
    • (1994) Mycopathologia , vol.125 , pp. 157-162
    • Cotty, P.J.1
  • 11
    • 0023717930 scopus 로고
    • Simple fluorescence method for rapid estimation of aflatoxin levels in a solid culture medium
    • Cotty, P. J. 1988. Simple fluorescence method for rapid estimation of aflatoxin levels in a solid culture medium. Appl. Environ. Microbiol. 54:274-276.
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 274-276
    • Cotty, P.J.1
  • 12
    • 0001698624 scopus 로고
    • Virulence and cultural characteristics of two Aspergillus flavus strains pathogenic on cotton
    • Cotty, P. J. 1989. Virulence and cultural characteristics of two Aspergillus flavus strains pathogenic on cotton. Phytopathology 79:808-814.
    • (1989) Phytopathology , vol.79 , pp. 808-814
    • Cotty, P.J.1
  • 13
    • 0002446416 scopus 로고
    • Agriculture, aflatoxins and Aspergillus
    • K. Powell (ed.), Plenum Press, New York, N.Y.
    • Cotty, P. J., D. S. Bayman, D. S. Egel, and K. S. Elias. 1994. Agriculture, aflatoxins and Aspergillus, p. 1-27. In K. Powell (ed.), The genus Aspergillus. Plenum Press, New York, N.Y.
    • (1994) The Genus Aspergillus , pp. 1-27
    • Cotty, P.J.1    Bayman, D.S.2    Egel, D.S.3    Elias, K.S.4
  • 14
    • 0028235528 scopus 로고
    • Variability among atoxigenic Aspergillus flavus strains in ability to prevent aflatoxin contamination and production of aflatoxin biosynthetic pathway enzymes
    • Cotty, P. J., and D. Bhatnagar. 1994. Variability among atoxigenic Aspergillus flavus strains in ability to prevent aflatoxin contamination and production of aflatoxin biosynthetic pathway enzymes. Appl. Environ. Microbiol. 60:2248-2251.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 2248-2251
    • Cotty, P.J.1    Bhatnagar, D.2
  • 15
    • 0032902401 scopus 로고    scopus 로고
    • Divergence of West African and North American communities of Aspergillus section Flavi
    • Cotty, P. J., and K. F. Cardwell. 1999. Divergence of West African and North American communities of Aspergillus section Flavi. Appl. Environ. Microbiol. 65:2264-2266.
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 2264-2266
    • Cotty, P.J.1    Cardwell, K.F.2
  • 16
    • 0023903976 scopus 로고
    • Enzymes and aflatoxin biosynthesis
    • Dutton, M. F. 1988. Enzymes and aflatoxin biosynthesis. Microbiol. Rev. 52:274-295.
    • (1988) Microbiol. Rev. , vol.52 , pp. 274-295
    • Dutton, M.F.1
  • 17
    • 0033583082 scopus 로고    scopus 로고
    • Characterization of the promoter for the gene encoding the aflatoxin biosynthetic pathway regulatory protein AFLR
    • Ehrlich, K. C., J. W. Cary, and B. G. Montalbano. 1999. Characterization of the promoter for the gene encoding the aflatoxin biosynthetic pathway regulatory protein AFLR. Biochim. Biophys. Acta 1444:412-417.
    • (1999) Biochim. Biophys. Acta , vol.1444 , pp. 412-417
    • Ehrlich, K.C.1    Cary, J.W.2    Montalbano, B.G.3
  • 18
    • 0033574753 scopus 로고    scopus 로고
    • Binding of the C6-zinc cluster protein, AFLR, to the promoters of aflatoxin pathway biosynthesis genes in Aspergillus parasiticus
    • Ehrlich, K. C., B. G. Montalbano, and J. W. Cary. 1999. Binding of the C6-zinc cluster protein, AFLR, to the promoters of aflatoxin pathway biosynthesis genes in Aspergillus parasiticus. Gene 230:249-257.
    • (1999) Gene , vol.230 , pp. 249-257
    • Ehrlich, K.C.1    Montalbano, B.G.2    Cary, J.W.3
  • 19
  • 20
    • 0037331126 scopus 로고    scopus 로고
    • Sequence comparison of aflR from different Aspergillus species provides evidence for variability in regulation of aflatoxin production
    • Ehrlich, K. C., B. G. Montalbano, and P. J. Cotty. 2003. Sequence comparison of aflR from different Aspergillus species provides evidence for variability in regulation of aflatoxin production. Fungal Genet. Biol. 38:63-74.
    • (2003) Fungal Genet. Biol. , vol.38 , pp. 63-74
    • Ehrlich, K.C.1    Montalbano, B.G.2    Cotty, P.J.3
  • 21
    • 0006668210 scopus 로고
    • Biosynthesis of aflatoxins. Part II
    • London
    • Heathcote, J. G., M. F. Dutton, and J. R. Hibbert. 1976. Biosynthesis of aflatoxins. Part II. Chem. Ind. (London) 20:270-272.
    • (1976) Chem. Ind. , vol.20 , pp. 270-272
    • Heathcote, J.G.1    Dutton, M.F.2    Hibbert, J.R.3
  • 22
    • 0023872473 scopus 로고
    • Biosynthetic origin of aflatoxin G1: Confirmation of sterigmatocystin and lack of confirmation of aflatoxin B1 as precursors
    • Henderberg, A., J. W. Bennett, and L. S. Lee. 1988. Biosynthetic origin of aflatoxin G1: confirmation of sterigmatocystin and lack of confirmation of aflatoxin B1 as precursors. J. Gen. Microbiol. 134:661-667.
    • (1988) J. Gen. Microbiol. , vol.134 , pp. 661-667
    • Henderberg, A.1    Bennett, J.W.2    Lee, L.S.3
  • 23
    • 0029131763 scopus 로고
    • The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis
    • Hohn, T. M., A. E. Desjardins, and S. P. McCormick. 1995. The Tri4 gene of Fusarium sporotrichioides encodes a cytochrome P450 monooxygenase involved in trichothecene biosynthesis. Mol. Gen. Genet. 248:95-102.
    • (1995) Mol. Gen. Genet. , vol.248 , pp. 95-102
    • Hohn, T.M.1    Desjardins, A.E.2    McCormick, S.P.3
  • 24
    • 0023630597 scopus 로고
    • Aspergillus nomius, a new aflatoxin-producing species related to Aspergillus flavus and Aspergillus tamarii
    • Kurtzman, C. P., B. W. Horn, and C. W. Hesseltine. 1987. Aspergillus nomius, a new aflatoxin-producing species related to Aspergillus flavus and Aspergillus tamarii. Antonie Leeuwenhoek 53:147-158.
    • (1987) Antonie Leeuwenhoek , vol.53 , pp. 147-158
    • Kurtzman, C.P.1    Horn, B.W.2    Hesseltine, C.W.3
  • 25
    • 0015926342 scopus 로고
    • Metabolism of aflatoxin B1 and aflatoxin G1 by Aspergillus parasticus
    • Maggon, K. K., and T. A. Venkitasubramaian. 1973. Metabolism of aflatoxin B1 and aflatoxin G1 by Aspergillus parasticus. Experientia 29:1210-1212.
    • (1973) Experientia , vol.29 , pp. 1210-1212
    • Maggon, K.K.1    Venkitasubramaian, T.A.2
  • 26
    • 0001038483 scopus 로고    scopus 로고
    • Enzymology and molecular biology of aflatoxin biosynthesis
    • Minto, R. E., and C. A. Townsend. 1997. Enzymology and molecular biology of aflatoxin biosynthesis. Chem. Rev. 97:2537-2555.
    • (1997) Chem. Rev. , vol.97 , pp. 2537-2555
    • Minto, R.E.1    Townsend, C.A.2
  • 27
    • 0000092138 scopus 로고    scopus 로고
    • Phylogenetic relationships in Aspergillus based on rDNA sequence analysis
    • R. A. Samson and J. I. Pitt (ed.), Harwood Publishers, Reading, United Kingdom
    • Peterson, S. W. 1997. Phylogenetic relationships in Aspergillus based on rDNA sequence analysis, p. 323-356. In R. A. Samson and J. I. Pitt (ed.), Classification of Penicillium and Aspergillus: integration of modern taxonomic methods. Harwood Publishers, Reading, United Kingdom.
    • (1997) Classification of Penicillium and Aspergillus: Integration of Modern Taxonomic Methods , pp. 323-356
    • Peterson, S.W.1
  • 28
    • 0030946049 scopus 로고    scopus 로고
    • Ord1, an oxidoreductase gene responsible for conversion of O-methylsterigmatocystin to aflatoxin in Aspergillus flavus
    • Prieto, R., and C. P. Woloshuk. 1997. ord1, an oxidoreductase gene responsible for conversion of O-methylsterigmatocystin to aflatoxin in Aspergillus flavus. Appl. Environ. Microbiol. 63:1661-1666.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 1661-1666
    • Prieto, R.1    Woloshuk, C.P.2
  • 29
    • 0037094126 scopus 로고    scopus 로고
    • Synthesis of 11-hydroxyl O-methylsterigmatocystin and the role of a cytochrome P-450 in the final step of aflatoxin biosynthesis
    • Udwary, D. W., L. K. Casillas, and C. A. Townsend. 2002. Synthesis of 11-hydroxyl O-methylsterigmatocystin and the role of a cytochrome P-450 in the final step of aflatoxin biosynthesis. J. Am. Chem. Soc. 124:5294-5303.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 5294-5303
    • Udwary, D.W.1    Casillas, L.K.2    Townsend, C.A.3
  • 30
    • 0000066488 scopus 로고    scopus 로고
    • Incorporation of molecular oxygen in aflatoxin B1 biosynthesis
    • Watanabe, C. M., and C. A. Townsend. 1996. Incorporation of molecular oxygen in aflatoxin B1 biosynthesis. J. Org. Chem. 61:1990-1993.
    • (1996) J. Org. Chem. , vol.61 , pp. 1990-1993
    • Watanabe, C.M.1    Townsend, C.A.2
  • 32
    • 0028013081 scopus 로고
    • The alcohol dehydrogenase gene adh1 is induced in Aspergillus flavus grown on medium conducive to aflatoxin biosynthesis
    • Woloshuk, C. P., and G. A. Payne. 1994. The alcohol dehydrogenase gene adh1 is induced in Aspergillus flavus grown on medium conducive to aflatoxin biosynthesis. Appl. Environ. Microbiol. 60:670-676.
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 670-676
    • Woloshuk, C.P.1    Payne, G.A.2
  • 33
    • 0023806863 scopus 로고
    • Isolation and characterization of Aspergillus parasiticus mutants with impaired aflatoxin production by a novel tip culture method
    • Yabe, K., H. Nakamura, Y. Ando, N. Terakado, H. Nakajima, and T. Hamasaki. 1988. Isolation and characterization of Aspergillus parasiticus mutants with impaired aflatoxin production by a novel tip culture method. Appl. Environ. Microbiol. 54:2096-2100.
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 2096-2100
    • Yabe, K.1    Nakamura, H.2    Ando, Y.3    Terakado, N.4    Nakajima, H.5    Hamasaki, T.6
  • 34
    • 0032875828 scopus 로고    scopus 로고
    • Enzymatic formation of G-group aflatoxins and biosynthetic relationship between G- And B-group aflatoxins
    • Yabe, K., M. Nakamura, and T. Hamasaki. 1999. Enzymatic formation of G-group aflatoxins and biosynthetic relationship between G- and B-group aflatoxins. Appl. Environ. Microbiol. 65:3867-3872.
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 3867-3872
    • Yabe, K.1    Nakamura, M.2    Hamasaki, T.3
  • 36
    • 0034129481 scopus 로고    scopus 로고
    • Genes encoding cytochrome P450 and monooxygenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus
    • Yu, J., P. K. Chang, D. Bhatnagar, and T. E. Cleveland. 2000. Genes encoding cytochrome P450 and monooxygenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus. Appl. Microbiol. Biotechnol. 53:583-590.
    • (2000) Appl. Microbiol. Biotechnol. , vol.53 , pp. 583-590
    • Yu, J.1    Chang, P.K.2    Bhatnagar, D.3    Cleveland, T.E.4
  • 37
    • 0030907724 scopus 로고    scopus 로고
    • A, a gene encoding a cytochrome P-450 monooxygenase, is involved in the conversion of averantin to averufin in aflatoxin biosynthesis in Aspergillus parasiticus
    • Yu, J., P.-K. Chang, J. W. Cary, D. Bhatnagar, and T. E. Cleveland. 1997. avnA, a gene encoding a cytochrome P-450 monooxygenase, is involved in the conversion of averantin to averufin in aflatoxin biosynthesis in Aspergillus parasiticus. Appl. Environ. Microbiol. 63:1349-1356.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 1349-1356
    • Yu, J.1    Chang, P.-K.2    Cary, J.W.3    Bhatnagar, D.4    Cleveland, T.E.5
  • 39
    • 0031764374 scopus 로고    scopus 로고
    • Characterization of the critical amino acids of an Aspergillus parasiticus cytochrome P-450 monooxygenase encoded by ordA that is involved in the biosynthesis of aflatoxins B1, G1, B2, and G2
    • Yu, J., P. K. Chang, K. C. Ehrlich, J. W. Cary, B. Montalbano, J. M. Dyer, D. Bhatnagar, and T. E. Cleveland. 1998. Characterization of the critical amino acids of an Aspergillus parasiticus cytochrome P-450 monooxygenase encoded by ordA that is involved in the biosynthesis of aflatoxins B1, G1, B2, and G2. Appl. Environ. Microbiol. 64:4834-4841.
    • (1998) Appl. Environ. Microbiol. , vol.64 , pp. 4834-4841
    • Yu, J.1    Chang, P.K.2    Ehrlich, K.C.3    Cary, J.W.4    Montalbano, B.5    Dyer, J.M.6    Bhatnagar, D.7    Cleveland, T.E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.