-
1
-
-
0024601010
-
PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
-
Auger KR, Serunian LA, Soltoff SP, Libby P, Cantley LC 1989 PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell 57:167-175
-
(1989)
Cell
, vol.57
, pp. 167-175
-
-
Auger, K.R.1
Serunian, L.A.2
Soltoff, S.P.3
Libby, P.4
Cantley, L.C.5
-
3
-
-
0029823946
-
A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphophate formation in chemoattractant-stimulated human neutrophils
-
Ptasznik A, Prossnitz ER, Yoshikawa D, Smrcka A, Bokoch GM 1996 A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphophate formation in chemoattractant-stimulated human neutrophils. J Biol Chem 271:25204-25207
-
(1996)
J Biol Chem
, vol.271
, pp. 25204-25207
-
-
Ptasznik, A.1
Prossnitz, E.R.2
Yoshikawa, D.3
Smrcka, A.4
Bokoch, G.M.5
-
4
-
-
0028334738
-
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by Gβ-γ subunits
-
Stephans L, Smrcka A, Cooke FT, Jackson TJ, Sternweis P, Hawkins PT 1994 A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by Gβ-γ subunits. Cell 77:83-93
-
(1994)
Cell
, vol.77
, pp. 83-93
-
-
Stephans, L.1
Smrcka, A.2
Cooke, F.T.3
Jackson, T.J.4
Sternweis, P.5
Hawkins, P.T.6
-
5
-
-
0027366440
-
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphophate-a new signaling pathway
-
Stephans LR, Jackson Tr, Hawkins PT 1993 Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphophate-a new signaling pathway. Biochim Biophys Acta 1179:27-75
-
(1993)
Biochim Biophys Acta
, vol.1179
, pp. 27-75
-
-
Stephans, L.R.1
Jackson, Tr.2
Hawkins, P.T.3
-
6
-
-
0028143039
-
Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression
-
Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM 1994 Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol Cell Biol 14:7466-7475
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7466-7475
-
-
Jhun, B.H.1
Rose, D.W.2
Seely, B.L.3
Rameh, L.4
Cantley, L.5
Saltiel, A.R.6
Olefsky, J.M.7
-
7
-
-
0029973135
-
Activated phosphatylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocarion in 3T3-L1 adipocytes
-
Martin SS, Haruta T, Morris A, Klippel A, Williams LT, Olefsky JM 1996 Activated phosphatylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocarion in 3T3-L1 adipocytes. J Biol Chem 271:17605-17608
-
(1996)
J Biol Chem
, vol.271
, pp. 17605-17608
-
-
Martin, S.S.1
Haruta, T.2
Morris, A.3
Klippel, A.4
Williams, L.T.5
Olefsky, J.M.6
-
8
-
-
0030575539
-
Phosphoinositide 3-kinase and the regulation of cell growth
-
Carpenter CL, Cantley LC 1996 Phosphoinositide 3-kinase and the regulation of cell growth. Biochim Biophys Acta 1288:M11-M16
-
(1996)
Biochim Biophys Acta
, vol.1288
-
-
Carpenter, C.L.1
Cantley, L.C.2
-
9
-
-
0029813084
-
Role of PI 3-kinase and SH-PTP2 in insulin action
-
Kasuga M 1996 Role of PI 3-kinase and SH-PTP2 in insulin action. Diabetic Med 13:S87-S89
-
(1996)
Diabetic Med
, vol.13
-
-
Kasuga, M.1
-
10
-
-
0030470754
-
The role of phosphoinositide 3-kinase in insulin signaling
-
Shepherd PR, Nave BT, O'Rahilly S 1946 The role of phosphoinositide 3-kinase in insulin signaling. J Mol Endocrinol 17:175-184
-
(1946)
J Mol Endocrinol
, vol.17
, pp. 175-184
-
-
Shepherd, P.R.1
Nave, B.T.2
O'Rahilly, S.3
-
12
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
Toker A, Cantley LC 1997 Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387:673676-676
-
(1997)
Nature
, vol.387
, pp. 673676-673676
-
-
Toker, A.1
Cantley, L.C.2
-
13
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol 3-OH kinase signal transduction
-
Burgering BM, Coffer PJ 1995 Protein kinase B (c-Akt) in phosphatidylinositol 3-OH kinase signal transduction. Nature 376:599-602
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
14
-
-
0029810181
-
Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation
-
Kohn AD, Takeuchi F, Roth A 1996 Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J Biol Chem 271:21920-21926
-
(1996)
J Biol Chem
, vol.271
, pp. 21920-21926
-
-
Kohn, A.D.1
Takeuchi, F.2
Roth, A.3
-
15
-
-
0002956168
-
The protein kinase encoded the akt proto-ocogene is a target of the PDGF-activated phosphoinositol 3-kinase
-
Franke TF 1495 The protein kinase encoded the akt proto-ocogene is a target of the PDGF-activated phosphoinositol 3-kinase. Cell 81:1-20
-
(1495)
Cell
, vol.81
, pp. 1-20
-
-
Franke, T.F.1
-
16
-
-
0027193913
-
Insulin-induced circular membrane ruffling on rat 1 cells expressing a high number of human insulin receptors: Circular ruffles caused by rapid actin reorganization exhibit high density of insulin receptors and phosphotyrosines
-
Li SL, Miyata Y, Yahara I, Fujita-Yamaguchi Y 1993 Insulin-induced circular membrane ruffling on rat 1 cells expressing a high number of human insulin receptors: circular ruffles caused by rapid actin reorganization exhibit high density of insulin receptors and phosphotyrosines. Exp Cell Res 205:353-360
-
(1993)
Exp Cell Res
, vol.205
, pp. 353-360
-
-
Li, S.L.1
Miyata, Y.2
Yahara, I.3
Fujita-Yamaguchi, Y.4
-
17
-
-
0026654125
-
The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
-
Ridley JA, Paterson FH, Johnston CL, Diekmann D, Hall A 1992 The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70:401-410
-
(1992)
Cell
, vol.70
, pp. 401-410
-
-
Ridley, J.A.1
Paterson, F.H.2
Johnston, C.L.3
Diekmann, D.4
Hall, A.5
-
18
-
-
0028264058
-
Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced ruffling
-
Kotani K, Yonezawa K, Hara K, Ueda H, Kitamura Y, Sakaue H, Ando A, Chavanaieu A, Calas B, Grigorescu F, Nishiyama M, Waterfield MD, Kasuga M 1994 Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced ruffling. EMBO J 13:2313-2321
-
(1994)
EMBO J
, vol.13
, pp. 2313-2321
-
-
Kotani, K.1
Yonezawa, K.2
Hara, K.3
Ueda, H.4
Kitamura, Y.5
Sakaue, H.6
Ando, A.7
Chavanaieu, A.8
Calas, B.9
Grigorescu, F.10
Nishiyama, M.11
Waterfield, M.D.12
Kasuga, M.13
-
19
-
-
0029850645
-
Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown
-
Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM 1996 Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown. Endocrinolgy 137:5045-5054
-
(1996)
Endocrinolgy
, vol.137
, pp. 5045-5054
-
-
Martin, S.S.1
Rose, D.W.2
Saltiel, A.R.3
Klippel, A.4
Williams, L.T.5
Olefsky, J.M.6
-
20
-
-
0030975196
-
Signaling by the posphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains
-
Klarlund J, Guilherme A, Holik JJ, Virbasius J, V, Chawla A, Czech MP 1997 Signaling by the posphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains. Science 275:1927-1930
-
(1997)
Science
, vol.275
, pp. 1927-1930
-
-
Klarlund, J.1
Guilherme, A.2
Holik, J.J.3
Virbasius, J.V.4
Chawla, A.5
Czech, M.P.6
-
21
-
-
0031939743
-
Regulation of GRP1-catalized ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate
-
Klarlund J, Rameh LE, Cantley LC, Buxton JM, Holik JJ, Sakelis C, Patki V, Corvera S, Czech MP 1998 Regulation of GRP1-catalized ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:1859-1864
-
(1998)
J Biol Chem
, vol.273
, pp. 1859-1864
-
-
Klarlund, J.1
Rameh, L.E.2
Cantley, L.C.3
Buxton, J.M.4
Holik, J.J.5
Sakelis, C.6
Patki, V.7
Corvera, S.8
Czech, M.P.9
-
22
-
-
0025923845
-
Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type
-
Haney PM, Slot JW, Piper RC, James DE, Mueckler M 1991 Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type. J Cell Biol 114:689-699
-
(1991)
J Cell Biol
, vol.114
, pp. 689-699
-
-
Haney, P.M.1
Slot, J.W.2
Piper, R.C.3
James, D.E.4
Mueckler, M.5
-
23
-
-
0028875678
-
Insulin-stimulated GLUT 4 translocation is mediated by a divergent intracellular signaling pathway
-
Haruta T, Morris AJ, Rose DW, Nelson JG, Mueckler M, Olefsky JM 1995 Insulin-stimulated GLUT 4 translocation is mediated by a divergent intracellular signaling pathway. J Biol Chem 270:27991-27994
-
(1995)
J Biol Chem
, vol.270
, pp. 27991-27994
-
-
Haruta, T.1
Morris, A.J.2
Rose, D.W.3
Nelson, J.G.4
Mueckler, M.5
Olefsky, J.M.6
-
24
-
-
0027391632
-
Direct analysis of the binding of the abl Src homology domain to the activated epidermal growth factor receptor
-
Zhu G, Decker SJ, Mayer BJ, Saltiel AR 1993 Direct analysis of the binding of the abl Src homology domain to the activated epidermal growth factor receptor. J Biol Chem 268:1775-1779
-
(1993)
J Biol Chem
, vol.268
, pp. 1775-1779
-
-
Zhu, G.1
Decker, S.J.2
Mayer, B.J.3
Saltiel, A.R.4
-
25
-
-
0023665224
-
A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does undergo endocytosis
-
McClain DA, Maegawa H, Lee J, Dull TJ, Ulrich A, Olefsky JM 1987 A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does undergo endocytosis. J Biol Chem 262:14663-14671
-
(1987)
J Biol Chem
, vol.262
, pp. 14663-14671
-
-
McClain, D.A.1
Maegawa, H.2
Lee, J.3
Dull, T.J.4
Ulrich, A.5
Olefsky, J.M.6
-
26
-
-
0016698833
-
Interaction of actin with phalloidin: Polymerization and stabilization of F-actin
-
Dancker P, Low I, Hasselbach W, Wieland T 1975 Interaction of actin with phalloidin: polymerization and stabilization of F-actin. Biochim Biophys Acta 400:407-414
-
(1975)
Biochim Biophys Acta
, vol.400
, pp. 407-414
-
-
Dancker, P.1
Low, I.2
Hasselbach, W.3
Wieland, T.4
-
27
-
-
0030766987
-
A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytosceletal rearrangements
-
D'Souza-Schorey C, Boshans RL, McDonough M, Stahl PD, Van Aelst I 1997 A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytosceletal rearrangements. EMBO J 16:5445-5454
-
(1997)
EMBO J
, vol.16
, pp. 5445-5454
-
-
D'Souza-Schorey, C.1
Boshans, R.L.2
McDonough, M.3
Stahl, P.D.4
Van Aelst, I.5
-
28
-
-
0029079431
-
A role of Rac in TIAM induced membrane ruffling and invasion
-
Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard LG 1995 A role of Rac in TIAM induced membrane ruffling and invasion. Nature 375:338-340
-
(1995)
Nature
, vol.375
, pp. 338-340
-
-
Michiels, F.1
Habets, G.G.2
Stam, J.C.3
Van Der Kammen, R.A.4
Collard, L.G.5
-
29
-
-
0032559211
-
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos
-
Nimnual AS, Yatsula BA, Bar-Sagi D 1998 Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. Science 279:560-563
-
(1998)
Science
, vol.279
, pp. 560-563
-
-
Nimnual, A.S.1
Yatsula, B.A.2
Bar-Sagi, D.3
-
30
-
-
15144353776
-
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
-
Han J, Luby-Phelps K, Das B, Shu X, Xia Y, Mosteller RD, Krishna UM, Falck JR, White MA, Broek D 1998 Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 279:560
-
(1998)
Science
, vol.279
, pp. 560
-
-
Han, J.1
Luby-Phelps, K.2
Das, B.3
Shu, X.4
Xia, Y.5
Mosteller, R.D.6
Krishna, U.M.7
Falck, J.R.8
White, M.A.9
Broek, D.10
-
31
-
-
0032485074
-
Structure of the Sec7 domain of the ARF exchange factor ARNO
-
Cherfils J, Menetrey J, Mathieu M, Le Bras G, Robineau S, Beraud-Dufor S, Antonny B, Chardin P 1998 Structure of the Sec7 domain of the ARF exchange factor ARNO. Nature 392:101105
-
(1998)
Nature
, vol.392
, pp. 101105
-
-
Cherfils, J.1
Menetrey, J.2
Mathieu, M.3
Le Bras, G.4
Robineau, S.5
Beraud-Dufor, S.6
Antonny, B.7
Chardin, P.8
-
32
-
-
0029757748
-
Identification of a novel Rac-1-interacting protein involved in membrane ruffling
-
Van Aelst L, Joneson T, Bar-Sagi D 1996 Identification of a novel Rac-1-interacting protein involved in membrane ruffling. EMBO J 15:3778-3786
-
(1996)
EMBO J
, vol.15
, pp. 3778-3786
-
-
Van Aelst, L.1
Joneson, T.2
Bar-Sagi, D.3
-
33
-
-
0028925711
-
Rho-related proteins: Actin cytoskeleton and cell cycle
-
Ridley JA 1995 Rho-related proteins: actin cytoskeleton and cell cycle. Curr Opin Gen Dev 5:30
-
(1995)
Curr Opin Gen Dev
, vol.5
, pp. 30
-
-
Ridley, J.A.1
-
34
-
-
0028036684
-
The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
-
Chong LD, Traynor-Kaplan A, Bokoch GM, Schwartz MA 1994 The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79:507-513
-
(1994)
Cell
, vol.79
, pp. 507-513
-
-
Chong, L.D.1
Traynor-Kaplan, A.2
Bokoch, G.M.3
Schwartz, M.A.4
-
35
-
-
0028174102
-
α-Actinin and vinculin are P1P2-binding proteins involved in signaling by tyrosine kinase
-
Fukami K, Endo T, Imamura M, Takenawa T 1994 α-Actinin and vinculin are P1P2-binding proteins involved in signaling by tyrosine kinase. J Biol Chem 269:1518-1522
-
(1994)
J Biol Chem
, vol.269
, pp. 1518-1522
-
-
Fukami, K.1
Endo, T.2
Imamura, M.3
Takenawa, T.4
-
36
-
-
0026756594
-
Requirement of phosphatidylinositol 4,5-bisphosphate for α-actinin function
-
Fukami K, Furuhashi K, Inagaki M, Endo T, Hatano S, Takenawa T 1992 Requirement of phosphatidylinositol 4,5-bisphosphate for α-actinin function. Nature 359:150-152
-
(1992)
Nature
, vol.359
, pp. 150-152
-
-
Fukami, K.1
Furuhashi, K.2
Inagaki, M.3
Endo, T.4
Hatano, S.5
Takenawa, T.6
-
37
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S 1991 Oncogenes and signal transduction. Cell 64:281-302
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
Soltoff, S.7
-
38
-
-
0028918408
-
Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
-
Hu Q, Klippel A, Muslin AJ, Fantl WJ, Williams LT 1995 Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 268:100-102
-
(1995)
Science
, vol.268
, pp. 100-102
-
-
Hu, Q.1
Klippel, A.2
Muslin, A.J.3
Fantl, W.J.4
Williams, L.T.5
|