-
1
-
-
8644277475
-
-
note
-
I have taken Peter at his word and this account is not a comprehensive review but a personal journey through the forest of organic chemistry. I apologize for only passing credit to the chemical literature and the discoveries of others that made our work possible.
-
-
-
-
9
-
-
8644270822
-
-
note
-
I later learned that his wife apparently preferred the bustle and bright lights of London to the pastoral scholarly life of Cambridge!
-
-
-
-
10
-
-
37049128325
-
-
Fawcett, C. H.; Spencer, D. M.; Wain, R. L.; Fallis, A. G.; Jones, E. R. H.; Lequan, M.; Page, C. B.; Thaller, V.; Shubrook, D. C.; Whitham, P. M. J. Chem. Soc. C 1968, 2455.
-
(1968)
J. Chem. Soc. C
, pp. 2455
-
-
Fawcett, C.H.1
Spencer, D.M.2
Wain, R.L.3
Fallis, A.G.4
Jones, E.R.H.5
Lequan, M.6
Page, C.B.7
Thaller, V.8
Shubrook, D.C.9
Whitham, P.M.10
-
11
-
-
37049137774
-
-
(a) Fallis, A. G.; Jones, E. R. H.; Thaller, V. J. Chem. Soc., Chem. Commun. 1969, 924.
-
(1969)
J. Chem. Soc., Chem. Commun.
, pp. 924
-
-
Fallis, A.G.1
Jones, E.R.H.2
Thaller, V.3
-
12
-
-
0039057563
-
-
(b) Fallis, A. G.; Hearn, M. T. W.; Jones, E. R. H.; Thaller, V.; Turner, J. L. J. Chem. Soc., Perkin Trans. 1 1973, 743.
-
(1973)
J. Chem. Soc., Perkin Trans. 1
, pp. 743
-
-
Fallis, A.G.1
Hearn, M.T.W.2
Jones, E.R.H.3
Thaller, V.4
Turner, J.L.5
-
14
-
-
8644244209
-
-
Viehe, H. J., Ed.; M. Dekker: New York, NY
-
Cadiot, P.; Chodkiewicz, W. In Chemistry of Acetylenes; Viehe, H. J., Ed.; M. Dekker: New York, NY, 1969, 616.
-
(1969)
Chemistry of Acetylenes
, pp. 616
-
-
Cadiot, P.1
Chodkiewicz, W.2
-
15
-
-
0041353886
-
-
Reed, D. W.; Polichuk, D. R.; Buist, P. H.; Ambrose, S. J.; Sasata, R. J.; Savile, C. K.; Ross, A. R. S.; Covello, P. S. J. Am. Chem. Soc. 2003, 125, 10635.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 10635
-
-
Reed, D.W.1
Polichuk, D.R.2
Buist, P.H.3
Ambrose, S.J.4
Sasata, R.J.5
Savile, C.K.6
Ross, A.R.S.7
Covello, P.S.8
-
18
-
-
0001063333
-
-
Shea, K. J.; Gilman, J. W.; Haffner, C. D.; Dougherty, T. K. J. Am. Chem. Soc. 1986, 108, 4953.
-
(1986)
J. Am. Chem. Soc.
, vol.108
, pp. 4953
-
-
Shea, K.J.1
Gilman, J.W.2
Haffner, C.D.3
Dougherty, T.K.4
-
19
-
-
0028300090
-
-
(a) Nicolaou, K. C.; Claiborne, C. F.; Nantermet, P. G.; Couladouros, E. A.; Sorensen, E. J. J. Am. Chem. Soc. 1994, 116, 1591.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 1591
-
-
Nicolaou, K.C.1
Claiborne, C.F.2
Nantermet, P.G.3
Couladouros, E.A.4
Sorensen, E.J.5
-
20
-
-
0032212707
-
-
(b) Morihira, K.; Nishimori, T.; Kusama, H.; Horiguchi, Y.; Kuwajima, I.; Tsuruo,T. Bioorg. Med. Chem. Lett. 1998, 8, 2973.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 2973
-
-
Morihira, K.1
Nishimori, T.2
Kusama, H.3
Horiguchi, Y.4
Kuwajima, I.5
Tsuruo, T.6
-
21
-
-
0038796985
-
-
(c) Smil, D. V.; Laurent, A.; Fallis, A. G. Tetrahedron Lett. 2003, 44, 5129.
-
(2003)
Tetrahedron Lett.
, vol.44
, pp. 5129
-
-
Smil, D.V.1
Laurent, A.2
Fallis, A.G.3
-
22
-
-
0027317232
-
-
(a) Lu, Y.-F.; Harwig, C. W.; Fallis, A. G. J. Org. Chem. 1993, 58, 4202.
-
(1993)
J. Org. Chem.
, vol.58
, pp. 4202
-
-
Lu, Y.-F.1
Harwig, C.W.2
Fallis, A.G.3
-
23
-
-
0029552452
-
-
(b) Lu, Y.-F.; Harwig, C. W.; Fallis, A. G. Can. J. Chem. 1995, 73, 2253.
-
(1995)
Can. J. Chem.
, vol.73
, pp. 2253
-
-
Lu, Y.-F.1
Harwig, C.W.2
Fallis, A.G.3
-
24
-
-
0030678160
-
-
Harwig, C. W.; Py, S.; Fallis, A. G. J. Org. Chem. 1997, 62, 7902.
-
(1997)
J. Org. Chem.
, vol.62
, pp. 7902
-
-
Harwig, C.W.1
Py, S.2
Fallis, A.G.3
-
26
-
-
8644247018
-
-
(a) Okude, Y.; Hirano, S.; Hiyama, T.; Nozaki, H. J. Am. Chem. Soc. 1977, 99, 3175.
-
(1977)
J. Am. Chem. Soc.
, vol.99
, pp. 3175
-
-
Okude, Y.1
Hirano, S.2
Hiyama, T.3
Nozaki, H.4
-
27
-
-
8644277474
-
-
(b) Jin, H.; Uenishi, J.; Christ, W. J.; Kishi, Y. J. Am. Chem. Soc. 1987, 109, 5644.
-
(1987)
J. Am. Chem. Soc.
, vol.109
, pp. 5644
-
-
Jin, H.1
Uenishi, J.2
Christ, W.J.3
Kishi, Y.4
-
28
-
-
0028213554
-
-
Didier, E.; Fouque, F.; Taillepied, I.; Commerçon, A. Tetrahedron Lett. 1994, 35, 2349.
-
(1994)
Tetrahedron Lett.
, vol.35
, pp. 2349
-
-
Didier, E.1
Fouque, F.2
Taillepied, I.3
Commerçon, A.4
-
29
-
-
0032552099
-
-
Py, S.; Harwig, C. W.; Banerjee, S.; Brown, D. L.; Fallis, A. G. Tetrahedron Lett. 1998, 39, 6139.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 6139
-
-
Py, S.1
Harwig, C.W.2
Banerjee, S.3
Brown, D.L.4
Fallis, A.G.5
-
30
-
-
0034564008
-
-
Comanita, B. M.; Heuft, M. A.; Rietveld, T.; Fallis, A. G. Isr. J. Chem. 2000, 40, 241.
-
(2000)
Isr. J. Chem.
, vol.40
, pp. 241
-
-
Comanita, B.M.1
Heuft, M.A.2
Rietveld, T.3
Fallis, A.G.4
-
32
-
-
8644238461
-
-
note
-
Canada has a strategic grant program to support research in collaboration with an industrial partner, provided there is applied potential that will benefit society.
-
-
-
-
33
-
-
0030570266
-
-
Rubin, Y.; Parker, T. C.; Khan, S. I.; Holliman, C. L.; McElvany, S. W. J. Am. Chem. Soc. 1996, 118, 5308.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 5308
-
-
Rubin, Y.1
Parker, T.C.2
Khan, S.I.3
Holliman, C.L.4
McElvany, S.W.5
-
34
-
-
0034677083
-
-
Collins, S. K.; Yap, G. P. A.; Fallis, A. G. Angew. Chem. Int. Ed. 2000, 39, 385.
-
(2000)
Angew. Chem. Int. Ed.
, vol.39
, pp. 385
-
-
Collins, S.K.1
Yap, G.P.A.2
Fallis, A.G.3
-
35
-
-
0040188733
-
-
Collins, S. K.; Yap, G. P. A.; Fallis, A. G. Org. Lett. 2000, 2, 3185.
-
(2000)
Org. Lett.
, vol.2
, pp. 3185
-
-
Collins, S.K.1
Yap, G.P.A.2
Fallis, A.G.3
-
37
-
-
0033550487
-
-
(b) Nuckolls, C.; Katz, T. J.; Katz, G.; Collings, P. J.; Castellanos, L. J. Am. Chem. Soc. 1999, 121, 79.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 79
-
-
Nuckolls, C.1
Katz, T.J.2
Katz, G.3
Collings, P.J.4
Castellanos, L.5
-
38
-
-
0002577139
-
-
Collins, S. K.; Yapp, G. P.; Fallis, A. G. Org. Lett. 2002, 4, 11.
-
(2002)
Org. Lett.
, vol.4
, pp. 11
-
-
Collins, S.K.1
Yapp, G.P.2
Fallis, A.G.3
-
39
-
-
0002358128
-
-
(a) Ikegashira, K.; Nishihara, Y.; Hirabayashi, K.; Mori, A.; Hiyama, T. Chem. Commun. 1997, 1039.
-
(1997)
Chem. Commun.
, pp. 1039
-
-
Ikegashira, K.1
Nishihara, Y.2
Hirabayashi, K.3
Mori, A.4
Hiyama, T.5
-
40
-
-
0030812228
-
-
(b) Haley, M. M.; Bell, M. L.; Brand, S. C.; Kimball, D. B.; Pak, J. J.; Wan, W. B. Tetrahedron Lett. 1997, 38, 7483.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 7483
-
-
Haley, M.M.1
Bell, M.L.2
Brand, S.C.3
Kimball, D.B.4
Pak, J.J.5
Wan, W.B.6
-
41
-
-
0032482541
-
-
(c) Nishihara, Y.; Ikegashira, K.; Mori, A.; Hiyama, T. Tetrahedron Lett. 1998, 39, 4075.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 4075
-
-
Nishihara, Y.1
Ikegashira, K.2
Mori, A.3
Hiyama, T.4
-
42
-
-
0035818035
-
-
Heuft, M. A.; Collins, S. K.; Yap, G. P. A.; Fallis, A. G. Org. Lett. 2001, 3, 2883.
-
(2001)
Org. Lett.
, vol.3
, pp. 2883
-
-
Heuft, M.A.1
Collins, S.K.2
Yap, G.P.A.3
Fallis, A.G.4
-
43
-
-
0000251092
-
-
Joshi, H. S.; Jamshidi, R.; Tor, Y. Angew. Chem. Int. Ed. 1999, 38, 2722.
-
(1999)
Angew. Chem. Int. Ed.
, vol.38
, pp. 2722
-
-
Joshi, H.S.1
Jamshidi, R.2
Tor, Y.3
-
44
-
-
0038611226
-
-
Shvo, Y.; Taylor, E. C.; Mislow, K.; Raban, H. J. Am. Chem. Soc. 1967, 89, 4910.
-
(1967)
J. Am. Chem. Soc.
, vol.89
, pp. 4910
-
-
Shvo, Y.1
Taylor, E.C.2
Mislow, K.3
Raban, H.4
-
46
-
-
0000203486
-
-
For leading references for the syntheses of interesting acetylenic molecules see: (a) Wu, Z.; Lee, S.; Moore, J. S. J. Am. Chem. Soc. 1992, 114, 8730.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 8730
-
-
Wu, Z.1
Lee, S.2
Moore, J.S.3
-
47
-
-
6044266630
-
-
(b) Yu, Z.; Kahr, M.; Walker, K. L.; Wilkins, C. L.; Moore, J. S. J. Am. Chem. Soc. 1994, 116, 4537.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 4537
-
-
Yu, Z.1
Kahr, M.2
Walker, K.L.3
Wilkins, C.L.4
Moore, J.S.5
-
49
-
-
1842408893
-
-
(d) Boese, R.; Matzger, A. J.; Vollhardt, K. P. C. J. Am. Chem. Soc. 1997, 119, 2052.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2052
-
-
Boese, R.1
Matzger, A.J.2
Vollhardt, K.P.C.3
-
50
-
-
0030890894
-
-
(e) Haley, M. M.; Bell, M. L.; English, J. J.; Johnson, C. A.; Weakley, T. J. R. J. Am. Chem. Soc. 1997, 119, 2956.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 2956
-
-
Haley, M.M.1
Bell, M.L.2
English, J.J.3
Johnson, C.A.4
Weakley, T.J.R.5
-
51
-
-
0031007781
-
-
(f) Haley, M. M.; Brand, S. C.; Pak, J. J. Angew. Chem., Int. Ed. Engl. 1997, 36, 836.
-
(1997)
Angew. Chem., Int. Ed. Engl.
, vol.36
, pp. 836
-
-
Haley, M.M.1
Brand, S.C.2
Pak, J.J.3
-
52
-
-
0032541708
-
-
(g) Wan, W. B.; Kimball, D. B.; Haley, M. M. Tetrahedron Lett. 1998, 39, 6795.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 6795
-
-
Wan, W.B.1
Kimball, D.B.2
Haley, M.M.3
-
54
-
-
0032541708
-
-
(i) Wan, W. B.; Kimball, D. B.; Haley, M. M. Tetrahedron Lett. 1998, 39, 6795.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 6795
-
-
Wan, W.B.1
Kimball, D.B.2
Haley, M.M.3
-
56
-
-
0000240086
-
-
(k) Bunz, U. H. F.; Rubin, Y.; Tobe, Y. Chem. Soc. Rev. 1999, 28, 107.
-
(1999)
Chem. Soc. Rev.
, vol.28
, pp. 107
-
-
Bunz, U.H.F.1
Rubin, Y.2
Tobe, Y.3
-
57
-
-
0033568464
-
-
(l) Pak, J. J.; Weakley, T. J. R.; Haley, M. M. J. Am. Chem. Soc. 1999, 121, 8182.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 8182
-
-
Pak, J.J.1
Weakley, T.J.R.2
Haley, M.M.3
-
58
-
-
0033568464
-
-
(m) Pak, J. J.; Weakley, T. J. R.; Haley, M. M. J. Am. Chem. Soc. 1999, 121, 8182.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 8182
-
-
Pak, J.J.1
Weakley, T.J.R.2
Haley, M.M.3
-
59
-
-
0000871591
-
-
(n) Kehoe, J. M.; Kiley, J. H.; English, J. J.; Johnson, C. A.; Peterson, R. C.; Haley, M. M. Org. Lett. 2000, 2, 969.
-
(2000)
Org. Lett.
, vol.2
, pp. 969
-
-
Kehoe, J.M.1
Kiley, J.H.2
English, J.J.3
Johnson, C.A.4
Peterson, R.C.5
Haley, M.M.6
-
61
-
-
0037073667
-
-
(p) Boydston, A. J.; Haley, M. M.; Williams, R. V.; Armantrout, J. R. J. Org. Chem. 2002, 67, 8812.
-
(2002)
J. Org. Chem.
, vol.67
, pp. 8812
-
-
Boydston, A.J.1
Haley, M.M.2
Williams, R.V.3
Armantrout, J.R.4
-
63
-
-
0141853032
-
-
Heuft, M. A.; Collins, S. K.; Fallis, A. G. Org. Lett. 2003, 5, 1911.
-
(2003)
Org. Lett.
, vol.5
, pp. 1911
-
-
Heuft, M.A.1
Collins, S.K.2
Fallis, A.G.3
-
65
-
-
0037045235
-
-
Tsuzuki, S.; Honda, K.; Uchimaru, T.; Mikami, M.; Tanaba, K. J. Am. Chem. Soc. 2000, 124, 104.
-
(2000)
J. Am. Chem. Soc.
, vol.124
, pp. 104
-
-
Tsuzuki, S.1
Honda, K.2
Uchimaru, T.3
Mikami, M.4
Tanaba, K.5
-
66
-
-
8644224422
-
-
note
-
3 molecular modeling suite from Molecular Simulations Inc. San Diego, 1999. We thank S. Drouin and D. Fogg (University of Ottawa) for assistance.
-
-
-
-
67
-
-
8644253795
-
-
Ph.D. Thesis; University of Ottawa: Ontario
-
Heuft, M. A. Ph.D. Thesis; University of Ottawa: Ontario, 2003.
-
(2003)
-
-
Heuft, M.A.1
-
68
-
-
0343550390
-
-
Thorand, S.; Vogtle, F.; Krause, K. Angew. Chem. Int. Ed. 1999, 55, 3721.
-
(1999)
Angew. Chem. Int. Ed.
, vol.55
, pp. 3721
-
-
Thorand, S.1
Vogtle, F.2
Krause, K.3
-
69
-
-
8644232894
-
-
unpublished results
-
Clay, M. D. unpublished results.
-
-
-
Clay, M.D.1
-
70
-
-
0034608836
-
-
(a) Yamaguchi, S.; Akiyama, S.; Tamao, K. J. Am. Chem. Soc. 2000, 122, 6335.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 6335
-
-
Yamaguchi, S.1
Akiyama, S.2
Tamao, K.3
-
71
-
-
0000199222
-
-
(b) Yamaguchi, S.; Shiraska, T.; Tamo, K. Org. Lett. 2000, 2, 4129.
-
(2000)
Org. Lett.
, vol.2
, pp. 4129
-
-
Yamaguchi, S.1
Shiraska, T.2
Tamo, K.3
-
72
-
-
8644226426
-
-
M.Sc. Thesis; University of Ottawa: Ontario
-
Tiffen, J. L. M.Sc. Thesis; University of Ottawa: Ontario, 2002.
-
(2002)
-
-
Tiffen, J.L.1
-
76
-
-
0030029667
-
-
(a) Wong, T.; Tjepkema, M. W.; Audrain, H.; Wilson, P. D.; Fallis, A. G. Tetrahedron Lett. 1996, 37, 755.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 755
-
-
Wong, T.1
Tjepkema, M.W.2
Audrain, H.3
Wilson, P.D.4
Fallis, A.G.5
-
78
-
-
0033992071
-
-
(c) Forgione, P.; Wilson, P. D.; Fallis, A. G. Tetrahedron Lett. 2000, 41, 17.
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 17
-
-
Forgione, P.1
Wilson, P.D.2
Fallis, A.G.3
-
79
-
-
0033936114
-
-
(d) Forgione, P.; Wilson, P. D.; Yap, G. P. A.; Fallis, A. G. Synthesis 2000, 921.
-
(2000)
Synthesis
, pp. 921
-
-
Forgione, P.1
Wilson, P.D.2
Yap, G.P.A.3
Fallis, A.G.4
-
81
-
-
0141856130
-
-
Tessier, P. J.; Penwell, A. J.; Souza, F. E. S.; Fallis, A. G. Org. Lett. 2003, 5, 2989.
-
(2003)
Org. Lett.
, vol.5
, pp. 2989
-
-
Tessier, P.J.1
Penwell, A.J.2
Souza, F.E.S.3
Fallis, A.G.4
-
82
-
-
8644247795
-
-
M.Sc. Thesis; University of Ottawa: Ontario
-
Tessier, P. J. M.Sc. Thesis; University of Ottawa: Ontario, 2003.
-
(2003)
-
-
Tessier, P.J.1
-
84
-
-
0037155532
-
-
(a) Lei, A.; Srivastava, M.; Zhang, X. J. Org. Chem. 2002, 67, 1969.
-
(2002)
J. Org. Chem.
, vol.67
, pp. 1969
-
-
Lei, A.1
Srivastava, M.2
Zhang, X.3
-
85
-
-
3242684255
-
-
(b) Marsden, J. A.; Miller, J. J.; Haley, M. M. Angew. Chem. Int. Ed. 2004, 43, 1694.
-
(2004)
Angew. Chem. Int. Ed.
, vol.43
, pp. 1694
-
-
Marsden, J.A.1
Miller, J.J.2
Haley, M.M.3
-
86
-
-
8644288530
-
-
note
-
After submission of this manuscript for review, a current group member volunteered to examine this idea. The Grignard 134 could not be generated from 81 with magnesium turnings, but with Reike® magnesium it acted as a base and the chloride was eliminated to generate the triple bond (Scheme 13); consequently, commencing with a halobenzene is more prudent.
-
-
-
|