Skin absorption and metabolism of a new vitamin E prodrug, δ-tocopherol-glucoside: In vitro evaluation in human skin models

Journal of Controlled Release

Volumn 100, Issue 2, 2004, Pages 221-231

  Mavon, Alain ^a   Raufast, Véronique ^a   Redoulès, Daniel ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Tocopherol acetate; Tocopherol glucoside; Drug metabolism; Percutaneous absorption; Topical antioxidant

Indexed keywords

HUMAN SKIN MODELS; MYRITOL; TOCOPHEROL;

ABSORPTION; ANTIOXIDANTS; METABOLISM; PHYSIOLOGICAL MODELS; SKIN; VITAMINS;

DRUG PRODUCTS;

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; DELTA TOCOPHEROL GLUCOSIDE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL MODEL; COMPARTMENT MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ABSORPTION; DRUG DIFFUSION; DRUG METABOLISM; DRUG TRANSFORMATION; EPIDERMIS; EXPERIMENTAL MODEL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PRIORITY JOURNAL; SKIN ABSORPTION; STRATUM CORNEUM; TOPICAL TREATMENT;

ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DERMIS; DIFFUSION CHAMBERS, CULTURE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMIS; GLUCOSIDES; HUMANS; PRODRUGS; SKIN; SKIN ABSORPTION; TOCOPHEROLS; VITAMIN E;

EID: 8544254691     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.08.012     Document Type: Article

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