Photoprotective action of topically applied vitamin E

Drug Metabolism Reviews

Volumn 32, Issue 3-4, 2000, Pages 413-420

  Krol, E S ^a   Kramer Stickland, K A ^a   Liebler, D C ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Photochemistry; Sunscreen; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; RADIOPROTECTIVE AGENT; SUNSCREEN;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; MOUSE; NONHUMAN; SKIN CANCER; ULTRAVIOLET RADIATION; ANIMAL; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; PHOTOCHEMISTRY; RADIATION EXPOSURE; REVIEW; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTIOXIDANTS; HUMANS; MOLECULAR CONFORMATION; PHOTOCHEMISTRY; RADIATION-PROTECTIVE AGENTS; SUNSCREENING AGENTS; ULTRAVIOLET RAYS; VITAMIN E;

EID: 0034353419     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-100102343     Document Type: Conference Paper

References (36)

1. Evidence for the photoprotective effects of vitamin E
2. Potentials and limitations of the natural antioxidants RRR-alpha-tocopherol, L-ascorbic acid and β-carotene in cutaneous photoprotection
3. Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin
4. Alkaline lability of fluorescent photoproducts produced in ultraviolet light-irradiated DNA
5. UV skin cancer: Specific p53 gene mutation in normal skin as a biologically relevant exposure measurement
6. The UV response involving the ras signalling pathway and AP-1 transcription factors is conserved between yeast and mammals
7. NF-kB activation by ultraviolet light not dependent on a nuclear signal
8. The role of metabolism in the antioxidant function of vitamin E
9. Antioxidant properties of α-tocopherol and α-tocotrienol
10. Tocopherone and epoxytocopherone products of vitamin E oxidation
11. Oxidation products of vitamin E and its model, 6-hydroxy-2,2,5,7,8-pentamethyl-chroman. V. Studies of the products of alkaline ferricyanide oxidation
12. Oxidation products of vitamin E and its model 6-hydroxy-2,2,5,7,8-pentamethylchroman. VIII. Oxidation with benzoyl peroxide
13. Oxidations of vitamin E (α-tocopherol) and its model compound 2,3,5,7,8-pentamethyl-6-hydroxychroman. A new dimer
14. Isolation of a trimer of (α-tocopherol from mammalian liver
15. Effect of alcohols on the oxidation of the vitamin E model compound, 2,2,5,7,8-pentamethyl-6-chromanol
16. -). II. Identification of the stable α-tocopherol oxidation products
17. The oxidation product from a-tocopherol and potassium ferricyanide and its reaction with ascorbic and hydrochloric acids
18. Topical vitamin E inhibition of immunosuppression and tumorigenesis induced by ultraviolet radiation
19. Photoprotective effect of superoxidescavenging antioxidants against ultraviolet radiation-induced chronic skin damage in the hairless mouse
20. Protective effect of alphatocopherol in carrier liposomes on ultraviolet-mediated human epidermal cell damage in vitro
21. Prevention of photocarcinogenesis by dietary vitamin E
22. The influence of topical and systemic vitamin E on ultraviolet light-induced skin damage in hairless mice
23. Evaluation of the photoprotective effect of oral vitamin E supplementation
24. Inhibition of UVB induced photodamage in mouse epidermis by topically applied α-tocopherol
25. Prevention of DNA photodamage by vitamin E compounds and sunscreens: Roles of ultraviolet absorbance and cellular uptake
26. The effect of vitamin E acetate on ultraviolet-induced mouse skin carcinogenesis
27. Uptake and bioconversion of αtocopheryl acetate to α-tocopherol in skin of hairless mice
28. Disposition and metabolism of topically administered α-tocopherol acetate: A common ingredient of commercially available sunscreens and cosmetics
29. Effect of UVB on hydrolysis of α-tocopherol acetate to α-tocopherol in mouse skin
30. Depletion of stratum corneum vitamin E: An early and sensitive in vivo marker of UV-induced photo-oxidation
31. Effects of UV light and tumor promoters on Vitamin E status in mouse skin
32. Efficacy of topically applied tocopherols and tocotrienols in protection of murine skin from oxidative damage induced by UV-irradiation
33. UVB induced photooxidation of vitamin E
34. Radical scavenging reactions of vitamin E and its model compound, 2,2,5,7,8-pentamethylchroman-6-ol in a tertbutylperoxyl radical generating system
35. Reaction of α-tocopherol with alkyl and alkylperoxyl radicals of methyl linoleate
36. Penetration and distribution of α-tocopherol, α- or γ-tocotrienols applied individually onto marine skin