Adenoviruses

Manual of Clinical Microbiology: Tenth Edition

Volumn 2-2, Issue , 2022, Pages 1600-1611

  Robinson, Christine ^a   Echavarria, Marcela ^b  

^a CHILDREN S HOSPITAL COLORADO   (United States)

^b University Hospital   (Argentina)

Author keywords

Adenoviruses; Gastrointestinal tracts; PCR; Serologic tests; Shell vial centrifugation culture (SVCC)

Indexed keywords

EID: 85188867897     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1128/9781555816728.ch101     Document Type: Chapter

References (82)

1. Adrian, T., G. Wadell, J. C. Hierholzer, and R. Wigand. 1986. DNA restriction analysis of adenovirus prototypes 1 to 41. Arch. Virol,. 91:277-290.
2. August, M. J., and A. L. Warford. 1987. Evaluation of a commercial monoclonal antibody for detection of adenovirus antigen. J. Clin. Microbiol. 25:2233-2235.
3. Banik, U., A. K. Adhikary, E. Suzuki, T. Inada, and N. Okabe. 2005. Multiplex PCR assay for rapid identification of oculopathogenic adenoviruses by amplification of the fiber and hexon genes. J. Clin. Microbiol. 43:1064-1068.
4. Bayon, M. N., and R. Drut. 1991. Cytologic diagnosis of adenovirus bronchopneumonia. Acta Cytol. 35:181-182.
5. Brown, M. 1990. Laboratory identification of adenoviruses associated with gastroenteritis in Canada from 1983 to 1986. J. Clin. Microbiol. 28:1525-1529.
6. Carballal, G., C. Videla, A. Misirlian, P. V. Requeijo, and M. C. Aguilar. 2002. Adenovirus type 7 associated with severe and fatal acute lower respiratory infections in Argentine children. BMC Pediatr. 2:6.
7. Centers for Disease Control and Prevention. 1998. Civilian outbreak of adenovirus acute respiratory disease-South Dakota, 1997. JAMA 280:596.
8. Childs, R. W., and C. S. Zerbe. 2009. Expanding multiviral reactive T cells from cord blood. Blood 114:1725-1726.
9. Claas, E. C., M. W. Schilham, C. S. de Brouwer, P. Hubacek, M. Echavarria, A. C. Lankester, M. J. van Tol, and A. C. Kroes. 2005. Internally controlled real-time PCR monitoring of adenovirus DNA load in serum or plasma of transplant recipients. J. Clin. Microbiol. 43:1738-1744.
10. Crawford-Miksza, L. K., and D. P. Schnurr. 1996. Adenovirus serotype evolution is driven by illegitimate recombination in the hypervariable regions of the hexon protein. Virology 224:357-367.
11. Damen, M., R. Minnaar, P. Glasius, A. van der Ham, G. Koen, P. Wertheim, and M. Beld. 2008. Real-time PCR with an internal control for detection of all known human adenovirus serotypes. J. Clin. Microbiol. 46:3997-4003.
12. Darr, S., I. Madisch, and A. Heim. 2008. Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia. Clin. Infect. Dis. 47:731-732.
13. de Jong, J. C., A. G. Wermenbol, M. W. Verweij-Uijterwaal, K. W. Slaterus, D. P. Wertheim-Van, G. J. van Doornum, S. H. Khoo, and J. C. Hierholzer. 1999. Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of species B1 and D, respectively. J. Clin. Microbiol. 37:3940-3945.
14. Durepaire, N., S. Ranger-Rogez, and F. Denis. 1996. Evaluation of rapid culture centrifugation method for adenovirus detection in stools. Diagn. Microbiol. Infect. Dis. 24:25-29.
15. Ebner, K., M. Suda, F. Watzinger, and T. Lion. 2005. Molecular detection and quantitative analysis of the entire spectrum of human adenoviruses by a two-reaction real-time PCR assay. J. Clin. Microbiol 43:3049-3053.
16. Echavarria, M. 2008. Adenoviruses in immunocompromised hosts. Clin. Microbiol. Rev. 21:704-715.
17. Echavarria, M., M. Forman, M. J. van Tol, J. M. Vossen, P. Charache, and A. C. Kroes. 2001. Prediction of severe disseminated adenovirus infection by serum PCR. Lancet 358:384-385.
18. Echavarria, M., D. Maldonado, G. Elbert, C. Videla, R. Rappaport, and G. Carballal. 2006. Use of PCR to demonstrate presence of adenovirus species B, C, or F as well as coinfection with two adenovirus species in children with flu-like symptoms. J. Clin. Microbiol. 44:625-627.
19. Echavarria, M. S., S. C. Ray, R. Ambinder, J. S. Dumler, and P. Charache. 1999. PCR detection of adenovirus in a bone marrow transplant recipient: hemorrhagic cystitis as a presenting manifestation of disseminated disease. J. Clin. Microbiol. 37:686-689.
20. Espy, M. J., J. C. Hierholzer, and T. F. Smith. 1987. The effect of centrifugation on the rapid detection of adenovirus in shell vials. Am. J. Clin. Pathol. 88:358-360.
21. Flomenberg, P., E. Gutierrez, V. Piaskowski, and J. T. Casper. 1997. Detection of adenovirus DNA in peripheral blood mononuclear cells by polymerase chain reaction assay. J. Med. Virol. 51:182-188.
22. Fujimoto, T., T. Okafuji, T. Okafuji, M. Ito, S. Nukuzuma, M. Chikahira, and O. Nishio. 2004. Evaluation of a bedside immunochromatographic test for detection of adenovirus in respiratory samples, by comparison to virus isolation, PCR, and real-time PCR. J. Clin. Microbiol. 42:5489-5492.
23. Garnett, C. T., G. Talekar, J. A. Mahr, W. Huang, Y. Zhang, D. A. Ornelles, and L. R. Gooding. 2009. Latent species C adenoviruses in human tonsil tissues. J. Virol. 83:2417-2428.
24. Gleaves, C. A., J. Militoni, and R. L. Ashley. 1993. An enzyme immunoassay for the direct detection of adenovirus in clinical specimens. Diagn. Microbiol. Infect. Dis. 17:57-59.
25. Grandien, M., C. A. Pettersson, L. Svensson, and I. Uhnoo. 1987. Latex agglutination test for adenovirus diagnosis in diarrheal disease. J. Med. Virol. 23:311-316.
26. Gray, G. C., T. McCarthy, M. G. Lebeck, D. P. Schnurr, K. L. Russell, A. E. Kajon, M. L. Landry, D. S. Leland, G. A. Storch, C. C. Ginocchio, C. C. Robinson, G. J. Demmler, M. A. Saubolle, S. C. Kehl, R. Selvarangan, M. B. Miller, J. D. Chappell, D. M. Zerr, D. L. Kiska, D. C. Halstead, A. W. Capuano, S. F. Setterquist, M. L. Chorazy, J. D. Dawson, and D. D. Erdman. 2007. Genotype prevalence and risk factors for severe clinical adenovirus infection, United States 2004-2006. Clin. Infect. Dis. 45:1120-1131.
27. Gu, Z., S. W. Belzer, C. S. Gibson, M. J. Bankowski, and R. T. Hayden. 2003. Multiplexed, real-time PCR for quantitative detection of human adenovirus. J. Clin. Microbiol. 41:4636-4641.
28. Gunson, R. N., A. R. Maclean, S. J. Shepherd, and W. F. Carman. 2009. Simultaneous detection and quantitation of cytomegalovirus, Epstein-Barr virus, and adenovirus by use of real-time PCR and pooled standards. J. Clin. Microbiol. 47:765-770.
29. Hammond, G. W., P. R. Hazelton, I. Chuang, and B. Klisko. 1981. Improved detection of viruses by electron microscopy after direct ultracentrifuge preparation of specimens. J. Clin. Microbiol. 14:210-221.
30. Heim, A., C. Ebnet, G. Harste, and P. Pring-Akerblom. 2003. Rapid and quantitative detection of human adenovirus DNA by real-time PCR. J. Med. Virol. 70:228-239.
31. Herrmann, J. E., D. M. Perron-Henry, and N. R. Blacklow. 1987. Antigen detection with monoclonal antibodies for the diagnosis of adenovirus gastroenteritis. J. Infect. Dis. 155:1167-1171.
32. Hierholzer, J. 1995. Adenoviruses, p. 169-188. In E. H. Lennette, D. A. Lennette, and E. T. Lennette (ed.), Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections. American Public Health Association, Washington, DC.
33. Hilleman, M. R., and J. Werner. 1954. Recovery of a new agent from patients with acute respiratory illness. Proc. Soc. Exp. Biol. Med. 85:183-188.
34. Houng, H. S., L. Lott, H. Gong, R. A. Kuschner, J. A. Lynch, and D. Metzgar. 2009. Adenovirus microsatellite reveals dynamics of transmission during a recent epidemic of human adenovirus serotype 14 infection. J. Clin. Microbiol. 47:2243-2248.
35. Huang, M. L., L. Nguy, J. Ferrenberg, M. Boeckh, A. Cent, and L. Corey. 2008. Development of multiplexed real-time quantitative polymerase chain reaction assay for detecting human adenoviruses. Diagn. Microbiol. Infect. Dis. 62:263-271.
36. Jartti, T., L. Jartti, V. Peltola, M. Waris, and O. Ruuskanen. 2008. Identification of respiratory viruses in asymptomatic subjects: asymptomatic respiratory viral infections. Pediatr. Infect. Dis. J. 27:1103-1107.
37. Jeulin, H., A. Salmon, P. Bordigoni, and V. Venard. 2010. Comparison of in-house real-time quantitative PCR to the Adenovirus R-Gene kit for determination of adenovirus load in clinical samples. J. Clin. Microbiol. 48:3132-3137.
38. Jones, M. S., B. Harrach, R. D. Ganac, M. M. Gozum, W. P. la Cruz, B. Riedel, C. Pan, E. L. Delwart, and D. P. Schnurr. 2007. New adenovirus species found in a patient presenting with gastroenteritis. J. Virol. 81:5978-5984.
39. Kajon, A. E., L. M. Dickson, P. Murtagh, D. Viale, G. Carballal, and M. Echavarria. 2010. Molecular characteriza- tionof an adenovirus 3/16 intertypic recombinant isolated in Argentina from an infant hospitalized with acute respiratory infection. J. Clin. Microbiol. 48:1494-1496.
40. Kim, S. R., C. S. Ki, and N. Y. Lee. 2009. Rapid detection and identification of 12 respiratory viruses using a dual priming oligonucleotide system-based multiplex PCR assay. J. Virol. Methods 156:111-116.
41. Kroes, A. C., E. P. de Klerk, A. C. Lankester, C. Malipaard, C. S. de Brouwer, E. C. Claas, E. C. Jol-van der Zijde, and M. J. van Tol. 2007. Sequential emergence of multiple adenovirus serotypes after pediatric stem cell transplantation. J. Clin. Virol. 38:341-347.
42. Kuypers, J., A. P. Campbell, A. Cent, L. Corey, and M. Boeckh. 2009. Comparison of conventional and molecular detection of respiratory viruses in hematopoietic cell transplant recipients. Transpl. Infect. Dis. 11:298-303.
43. Landry, M. L., and D. Ferguson. 2009. Polymerase chain reaction and the diagnosis of viral gastrointestinal disease due to cytomegalovirus, herpes simplex virus and adenovirus. J. Clin. Virol. 45:83-84.
44. Landry, M. L., and D. Ferguson. 2000. SimulFluor respiratory screen for rapid detection of multiple respiratory viruses in clinical specimens by immunofluorescence staining. J. Clin. Microbiol. 38:708-711.
45. Landry, M. L., C. K. Fong, K. Neddermann, L. Solomon, and G. D. Hsiung. 1987. Disseminated adenovirus infection in an immunocompromised host. Pitfalls in diagnosis. Am. J. Med. 83:555-559.
46. LaSala, P. R., K. K. Bufton, N. Ismail, and M. B. Smith. 2007. Prospective comparison of R-mix shell vial system with direct antigen tests and conventional cell culture for respiratory virus detection. J. Clin. Virol. 38:210-216.
47. Leruez-Ville, M., M. Chardin-Ouachee, B. Neven, C. Picard, I. Le Guinche, A. Fischer, C. Rouzioux, and S. Blanche. 2006. Description of an adenovirus A31 outbreak in a paediatric haematology unit. Bone Marrow Transplant. 38:23-28.
48. Leruez-Ville, M., V. Minard, F. Lacaille, A. Buzyn, E. Abachin, S. Blanche, F. Freymuth, and C. Rouzioux. 2004. Real-time blood plasma polymerase chain reaction for management of disseminated adenovirus infection. Clin. Infect. Dis. 38:45-52.
49. Lessler, J., N. G. Reich, R. Brookmeyer, T. M. Perl, K. E. Nelson, and D. A. Cummings. 2009. Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect. Dis. 9:291-300.
50. Levent, F., J. M. Greer, M. Snider, and G. J. Demmler-Harrison. 2009. Performance of a new immunochromatographic assay for detection of adenoviruses in children. J. Clin. Virol. 44:173-175.
51. Lion, T., R. Baumgartinger, F. Watzinger, S. Matthes-Martin, M. Suda, S. Preuner, B. Futterknecht, A. Lawitschka, C. Peters, U. Potschger, and H. Gadner. 2003. Molecular monitoring of adenovirus in peripheral blood after allogeneic bone marrow transplantation permits early diagnosis of disseminated disease. Blood 102:1114-1120.
52. Lipson, S. M., I. A. Poshni, R. L. Ashley, L. J. Grady, Z. Ciamician, and S. Teichberg. 1993. Presumptive identification of common adenovirus serotypes by the development of differential cytopathic effects in the human lung carcinoma (A549) cell culture. FEMS Microbiol. Lett. 113:175-182.
53. Louie, J. K., A. E. Kajon, M. Holodniy, L. Guardia-LaBar, B. Lee, A. M. Petru, J. K. Hacker, and D. P. Schnurr. 2008. Severe pneumonia due to adenovirus serotype 14: a new respiratory threat? Clin. Infect. Dis. 46:421-425.
54. Mahafzah, A. M., and M. L. Landry. 1989. Evaluation of im- munofluorescent reagents, centrifugation, and conventional cultures for the diagnosis of adenovirus infection. Diagn. Microbiol. Infect. Dis. 12:407-411.
55. Mahony, J., S. Chong, F. Merante, S. Yaghoubian, T. Sinha, C. Lisle, and R. Janeczko. 2007. Development of a respiratory virus panel test for detection of twenty human respiratory viruses by use of multiplex PCR and a fluid microbead-based assay. J. Clin. Microbiol. 45:2965-2970.
56. McCarthy, T., M. G. Lebeck, A. W. Capuano, D. P. Schnurr, and G. C. Gray. 2009. Molecular typing of clinical adenovirus specimens by an algorithm which permits detection of adenovirus coinfections and intermediate adenovirus strains. J. Clin. Virol. 46:80-84.
57. Metzgar, D., M. Osuna, A. E. Kajon, A. W. Hawksworth, M. Irvine, and K. L. Russell. 2007. Abrupt emergence of diverse species B adenoviruses at US military recruit training centers. J. Infect. Dis. 196:1465-1473.
58. Moore, P., A. D. Steele, G. Lecatsas, and J. J. Alexander. 1998. Characterisation of gastro-enteritis-associated adenoviruses in South Africa. S. Afr. Med. J. 88:1587-1592.
59. Morfin, F., S. Dupuis-Girod, E. Frobert, S. Mundweiler, D. Carrington, P. Sedlacek, M. Bierings, P. Cetkovsky, A. C. Kroes, M. J. van Tol, and D. Thouvenot. 2009. Differential susceptibility of adenovirus clinical isolates to cidofovir and ribavirin is not related to species alone. Antivir. Ther. 14:55-61.
60. Muller, R., A. Ditzen, K. Hille, M. Stichling, R. Ehricht, T. Illmer, G. Ehninger, and J. Rohayem. 2009. Detection of herpesvirus and adenovirus co-infections with diagnostic DNA-microarrays. J. Virol. Methods 155:161-166.
61. Murtagh, P., V. Giubergia, D. Viale, G. Bauer, and H. G. Pena. 2009. Lower respiratory infections by adenovirus in children. Clinical features and risk factors for bronchiolitis obliterans and mortality. Pediatr. Pulmonol. 44:450-456.
62. Olsen, M. A., K. M. Shuck, A. R. Sambol, S. M. Flor, J. O'Brien, and B. J. Cabrera. 1993. Isolation of seven respiratory viruses in shell vials: a practical and highly sensitive method. J. Clin. Microbiol 31:422-425.
63. Pabbaraju, K., K. L. Tokaryk, S. Wong, and J. D. Fox. 2008. Comparison of the Luminex xTAG respiratory viral panel with in-house nucleic acid amplification tests for diagnosis of respiratory virus infections. J. Clin. Microbiol. 46:3056-3062.
64. Pehler-Harrington, K., M. Khanna, C. R. Waters, and K. J. Henrickson. 2004. Rapid detection and identification of human adenovirus species by adenoplex, a multiplex PCR-en- zyme hybridization assay. J. Clin. Microbiol. 42:4072-4076.
65. Perlman, J., C. Gibson, S. B. Pounds, Z. Gu, M. J. Bankowski, and R. T. Hayden. 2007. Quantitative real-time PCR detection of adenovirus in clinical blood specimens: a comparison of plasma, whole blood and peripheral blood mononuclear cells. J. Clin. Virol. 40:295-300.
66. Rabalais, G. P., G. G. Stout, K. L. Ladd, and K. M. Cost. 1992. Rapid diagnosis of respiratory viral infections by using a shell vial assay and monoclonal antibody pool. J. Clin. Microbiol. 30:1505-1508.
67. Rocholl, C., K. Gerber, J. Daly, A. T. Pavia, and C. L. Byington. 2004. Adenoviral infections in children: the impact of rapid diagnosis. Pediatrics 113:e51-e56.
68. Romanowski, E. G., S. P. Bartels, R. Vogel, N. T. Wetherall, C. Hodges-Savola, R. P. Kowalski, K. A. Yates, P. R. Kinchington, and Y. J. Gordon. 2004. Feasibility of an antiviral clinical trial requiring cross-country shipment of conjunctival adenovirus cultures and recovery of infectious virus. Curr. Eye Res. 29:195-199.
69. Rowe, W. P., R. Heubner, L. Gilmore, R. Parrot, and T. Ward. 1953. Isolation of a cytopathogenic agent from human adenoids undergoing spontaneous degeneration in tissue culture. Proc. Soc. Exp. Biol. Med. 84:570-573.
70. Sambursky, R., S. Tauber, F. Schirra, K. Kozich, R. Davidson, and E. J. Cohen. 2006. The RPS adeno detector for diagnosing adenoviral conjunctivitis. Ophthalmology 113:1758-1764.
71. Sarantis, H., G. Johnson, M. Brown, M. Petric, and R. Tellier. 2004. Comprehensive detection and serotyping of human adenoviruses by PCR and sequencing. J. Clin. Microbiol. 42:3963-3969.
72. Shike, H., C. Shimizu, J. Kanegaye, J. L. Foley, and J. C. Burns. 2005. Quantitation of adenovirus genome during acute infection in normal children. Pediatr. Infect. Dis. J. 24:29-33.
73. Siamak, N. M., R. P. Kowalski, P. P. Thompson, E. G. Romanowski, R. M. Shanks, and Y. J. Gordon. 2009. RPS Adeno Detector. Ophthalmology 116:591.
74. Sprangers, M. C., W. Lakhai, W. Koudstaal, M. Verhoeven, B. F. Koel, R. Vogels, J. Goudsmit, M. J. Havenga, and S. Kostense. 2003. Quantifying adenovirus-neutralizing antibodies by luciferase transgene detection: addressing preexisting immunity to vaccine and gene therapy vectors. J. Clin. Microbiol. 41:5046-5052.
75. Thavagnanam, S., S. N. Christie, G. M. Doherty, P. V. Coyle, M. D. Shields, and L. G. Heaney. 2010. Respiratory viral infection in lower airways of asymptomatic children. Acta Paediatr. 99:394-398.
76. Udeh, B. L., J. E. Schneider, and R. L. Ohsfeldt. 2008. Cost effectiveness of a point-of-care test for adenoviral conjunctivitis. Am. J. Med. Sci. 336:254-264.
77. Uhnoo, I., L. Svensson, and G. Wadell. 1990. Enteric adenoviruses. Baillieres Clin. Gastroenterol. 4:627-642.
78. Van Doornum, G. J., and J. C. de Jong. 1998. Rapid shell vial culture technique for detection of enteroviruses and adenoviruses in fecal specimens: comparison with conventional virus isolation method. J. Clin. Microbiol 36:2865-2868.
79. Walsh, P., C. L. Overmyer, K. Pham, S. Michaelson, L. Gofman, L. DeSalvia, T. Tran, D. Gonzalez, J. Pusavat, M. Feola, K. T. Iacono, E. Mordechai, and M. E. Adelson. 2008. Comparison of respiratory virus detection rates for infants and toddlers by use of flocked swabs, saline aspirates, and saline aspirates mixed in universal transport medium for room temperature storage and shipping. J. Clin. Microbiol. 46:2374-2376.
80. Williams, K. M., A. L. Agwu, A. A. Dabb, M. A. Higman, D. M. Loeb, A. Valsamakis, and A. R. Chen. 2009. A clinical algorithm identifies high risk pediatric oncology and bone marrow transplant patients likely to benefit from treatment of adenoviral infection. J. Pediatr. Hematol. Oncol. 31:825-831.
81. Woods, G. L., M. Yamamoto, and A. Young. 1988. Detection of adenovirus by rapid 24-well plate centrifugation and conventional cell culture with dexamethasone. J. Virol. Methods 20:109-114.
82. Yusuf, U., G. A. Hale, J. Carr, Z. Gu, E. Benaim, P. Woodard, K. A. Kasow, E. M., Horwitz, W. Leung, D. K. Srivastava, R. Handgretinger, and R. T. Hayden. 2006. Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients. Transplantation 81:1398-1404.