Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia

Clinical Infectious Diseases

Volumn 47, Issue 5, 2008, Pages 731-732

  Darr, Sebastian ^a   Madisch, Ijad ^a   Heim, Albert ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CIDOFOVIR; RIBAVIRIN;

ANTIVIRAL ACTIVITY; HUMAN ADENOVIRUS; HUMAN ADENOVIRUS 14A; IC 50; INFECTION SENSITIVITY; LETTER; PRIORITY JOURNAL; VIRUS PNEUMONIA; VIRUS REPLICATION;

ADENOVIRIDAE INFECTIONS; ADENOVIRUSES, HUMAN; ANTIVIRAL AGENTS; CYTOSINE; HUMANS; INHIBITORY CONCENTRATION 50; PHOSPHONIC ACIDS; PNEUMONIA, VIRAL; RIBAVIRIN; UNITED STATES;

EID: 49449112621     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/590970     Document Type: Letter

References (7)

1. Louie JK, Kajon AE, Holodniy M, et al. Severe pneumonia due to adenovirus serotype 14: a new respiratory threat? Clin Infect Dis 2008; 46:421-5.
2. Centers for Disease Control and Prevention. Acute respiratory disease associated with adenovirus serotype 14 - four states, 2006-2007. MMWR Morb Mortal Wkly Rep 2007; 56:1181-4.
3. Metzgar D, Osuna M, Kajon AE, Hawksworth AW, Irvine M, Russell KL. Abrupt emergence of diverse species B adenoviruses at US military recruit training centers. J Infect Dis 2007; 196:1465-73.
4. Morfin F, Dupuis-Girod S, Mundweiler S, et al. In vitro susceptibility of adenovirus to antiviral drugs is species-dependent. Antivir Ther 2005; 10:225-9.
5. Stock R, Harste G, Madisch I, Heim A. A rapid quantitative PCR-based assay for testing antiviral agents against human adenoviruses demonstrates type specific differences in ribavirin activity. Antiviral Res 2006; 72:34-41.
6. Englund JA, Piedra PA, Jefferson LS, Wilson SZ, Taber LH, Gilbert BE. High-dose, short-duration ribavirin aerosol therapy in children with suspected respiratory syncytial virus infection. J Pediatr 1990; 117:313-20.
7. Cundy KC, Petty BG, Flaherty J, et al. Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 1995; 39:1247-52.