Protein analysis for diagnostic applications

Manual of Molecular and Clinical Laboratory Immunology: 7th edition

Volumn , Issue , 2022, Pages 7-21

  Remaley, Alan T ^a   Hortin, Glen L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Chromatography; Diagnostic purposes; Mass spectrometric methods; Multiplex immunoassays; Protein analysis; Proteome; Two dimensional gel electrophoresis

Indexed keywords

EID: 85182975928     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1128/9781555815905.ch3     Document Type: Chapter

References (79)

1. Anderson, N. L., and N. G. Anderson. 2002. The human plasma proteome: history, character, and diagnostic prospects. Mol. Cell. Proteomics 1:845-867.
2. Anderson, N. L., M. Polanski, R. Pieper, T. Gatlin, R. S. Tirumalai, T. P. Conrads, T. D. Veenstra, J. N. Adkins, J. G. Pounds, R. Fagan, and A. Lobley. 2004. The human plasma proteome: a nonredundant list developed by combination of four separate sources. Mol. Cell. Proteomics 3:311-326.
3. Bergen, H. R., III, S. R. Zeldenrust, M. L. Butz, D. S. Snow, P. J. Dyck, C. J. Klein, J. F. O'Brien, S. N. Thibodeau, and D. C. Muddiman. 2004. Identification of transthyretin variants by sequential proteomic and genomic analysis. Clin. Chem. 50:1544-1552.
4. Blick, K. E. 1996. Specifications for the selection of automated immunoassay systems. J. Clin. Immunol. 19:220-228.
5. Bossuyt, X. 2004. Interferences in clinical capillary zone electrophoresis of serum proteins. Electrophoresis 25: 1485-1487.
6. Bowen, R. A. R., Y. Chan, J. Cohen, N. N. Rehak, G. L. Hortin, G. Csako, and A. T. Remaley. 2005. Effect of blood collection tubes on total triiodothyronine and other laboratory assays. Clin. Chem. 51:424-433.
7. Buechler, K. E, S. Moi, B. Noar, D. McGrath, J. Villela, M. Clancy, A. Shenhav, A. Colleymore, G. Valkirs, T. Lee, et al. 1992. Simultaneous detection of seven drugs of abuse by the Triage panel for drugs of abuse. Clin. Chem. 38:1678-1684.
8. Cambiasco, C. L., H. A. Riccomi, P. L. Mason, and J. E Hermans. 1974. Automated nephelometric immunoassay: its application to the determination of hapten. J. Immunol. Methods 5:293-302.
9. Chaurand, P., M. E. Sanders, R. A. Jensen, and R. M. Caprioli. 2004. Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am. J. Pathol. 165:1057-1068.
10. Clarke, W., Z. Zhang, and D. W. Chan. 2003. The application of clinical proteomics to cancer and other diseases. Clin. Chem. Lab. Med. 41:1562-1570.
11. Dandliker, W. B., R. J. Kelly, J. Dandliker, J. Earquahar, and J. Levin. 1973. Fluorescence polarization immunoassay. Theory and experimental method. Immunochemistry 10: 219-227.
12. De Hoog, C. L., and M. Mann. 2004. Proteomics. Annu. Rev. Genomics Hum. Genet. 5:267-293.
13. Delehanty, J. B., and E. S. Ligler. 2002. A microarray immunoassay for simultaneous detection of proteins and bacteria. Anal. Chem. 74:5681-5687.
14. Diamandis, E. P., and T. K. Christopoulos. 1991. The biotin-(strept)avidin system: principles and applications in biotechnology. Clin. Chem. 37:625-636.
15. Dilena, B. A., and G. H. White. 1989. Interference with measurement of intact parathyrin in serum from renal dialysis patients. Clin. Chem. 35:1543-1544.
16. Drake, S. K., R. A. R. Bowen, A. T. Remaley, and G. L. Hortin. 2004. Potential interferences from blood collection tubes in mass spectrometric analyses of serum polypeptides. Clin. Chem. 50:2398-2401.
17. Dunbar, S. A., C. A. Vander Zee, K. G. Oliver, K. L. Karem, and J. W. Jacobson. 2003. Quantitative, multiplexed detection of bacterial pathogens: DNA and protein applications of the Luminex LabMAP system. J. Microbiol. Methods 53:245-252.
18. Fenn, J. B., M. Mann, D. K. Meng, S. E. Wong, and C. M. Whitehouse. 1989. Electrospray ionization for mass spectrometry of large biomolecules. Science 246:64-71.
19. Gerlach, R. W., R. J. White, S. N. Deming, J. A. Palasota, and J. M. van Emon. 1993. An evaluation of five commercial immunoassay data analysis software systems. Anal. Biochem. 212:185-193.
20. Geysen, H. M., T. J. Mason, and S. J. Rodda. 1988. Cognitive features of continuous antigenic epitopes. J. Mol. Recognit. 1:32-41.
21. Goldstein, D. E., R. R. Little, H. M. Wiedmeyer, J. D. England, and E. M. McKenzie. 1986. Glycated hemoglobin. Methodologies and clinical applications. Clin. Chem. 32 (Suppl.):B64-B70.
22. Gorg, A., W. Weiss, and M. J. Dunn. 2004. Current twodimensional electrophoresis technology for proteomics. Proteomics 4:3665-3685.
23. Gosling, J. P. 2000. Immunoassays: a Practical Approach. Oxford University Press, Oxford, United Kingdom.
24. Gross, S., and D. Piwnica-Worms. 2005. Spying on cancer: molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7:5-15.
25. Hamilton, R. G., and N. E. Adkinson, Jr. 2003. Clinical laboratory assessment of IgE-dependent hypersensitivity. J. Allergy Clin. Immunol. 111:S687-S701.
26. Harvey, M. A., C. A. Audette, and R. McDonogh. 1996. The use of microporous polymer membranes in immunoassays. IVD Technol. 2:34-39.
27. Heidelberger, M., and E W. Kendall. 1929. A quantitative study of the precipitin reaction between type III pneumococcus polysaccharide and purified homologous antibody. J. Exp. Med. 50:809-823.
28. Hemmila, I., S. Dakubu, V. M. Mukkala, H. Siitari, and T. Lovgren. 1984. Europium as a label in time-resolved immunofluorometric assays. Anal. Biochem. 137:335-343.
29. Henderson, D. R., S. B. Eriedman, J. D. Harris, W. B. Manning, and M. A. Zoccoli. 1986. CEDIA, a new homogeneous immunoassay system. Clin. Chem. 32:1637-1641.
30. Hermanson, G. T., A. K. Mallia, and P. K. Smith. 1992. Immobilized Affinity Ligand Techniques. Academic Press, San Diego, Calif.
31. Hortin, G. L. 2005. Can mass spectrometric protein profiling meet desired standards of clinical laboratory practice? Clin. Chem. 51:3-5.
32. Issaq, H. J., T. P. Conrads, G. M. Janini, and T. D. Veenstra. 2002. Methods for fractionation, separation and profiling of proteins and peptides. Electrophoresis 23: 3048-3061.
33. Issaq, H. J., T. D. Veenstra, T. P. Conrads, and D. Eelschow. 2002. The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification. Biochem. Biophys. Res. Commun. 292:587-592.
34. Jackson, T. M., and R. P. Ekins. 1986. Theoretical limitations on immunoassay sensitivity. Current practice and potential advantages of fluorescent Eu3+ chelates as non- radioisotopic tracers. J. Immunol. Methods 87:13-20.
35. Jain, K. K. 2003. Nanodiagnostics: applications of nanotechnology in molecular diagnostics. Expert Rev. Mol. Diagn. 3:153-161.
36. Jayasena, S. D. 1999. Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin. Chem. 45: 1628-1650.
37. Jeppson, J.-O., C.-B. Laurell, and B. Eranzen. 1979. Agarose gel electrophoresis. Clin. Chem. 25:629-638.
38. Kitade, T., K. Kitamura, T. Konishi, S. Takegami, T. Okuno, M. Ishikawa, M. Wakabayashi, K. Nishikawa, and Y. Muramatsu. 2004. Potentiometric immunosensor using artificial antibody based on molecularly imprinted polymers. Anal. Chem. 76:6802-6807.
39. Klee, G. G. 2004. Interferences in hormone immunoassays. Clin. Lab. Med. 24:1-18.
40. Kohler, G., and C. Milstein. 1975. Continuous culture of fused cells secreting specific antibody of predicted specificity. Nature 256:495-497.
41. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
42. Landsteiner, K., and D. H. Witt. 1926. Observations on the human blood groups. Irregular reactions. Iso-agglutinin in sera of group 4. The factor A1. J. Immunol. 2:221-229.
43. Levinson, S. S., and J. J. Miller. 2002. Towards a better understanding of heterophile (and the like) antibody interference with modern immunoassays. Clin. Chim. Acta 325:1-15.
44. Li, Z., C. J. Woo, M. D. Iglesias-Ussel, D. Ronai, and M. D. Scharff. 2004. The generation of antibody diversity through somatic hypermutation and class switch recombination. Genes Dev. 18:1-11.
45. Maachi, M., S. Eellahi, A. Regeniter, M. E. Diop, J. Capeau, J. Rossert, and J. P. Bastard. 2004. Patterns of proteinuria: urinary sodium dodecyl sulfate electrophoresis versus immunonephelometric protein marker measurement followed by interpretation with the knowledge-based system MDI-LabLink. Clin. Chem. 50:1834-1837.
46. Marvin, L. E, M. A. Roberts, and L. B. Fay. 2003. Matrix- assisted laser desorption/ionization time-of-flight mass spectrometry in clinical chemistry. Clin. Chim. Acta 337:11-21.
47. McNamara, J., H. Campos, J. Ordovas, J. Peterson, P. Wilson, and E. Schaefer. 1987. Effect of gender, age, and lipid status on low-density lipoprotein subfraction distribution: results of the Framingham Offspring Study. Arteriosclerosis 7:483-490.
48. Mehta, A. I., S. Ross, M. S. Lowenthal, V. Fusaro, D. A. Fishman, E. F. Petricoin III, and L. A. Liotta. 2003. Biomarker amplification by serum carrier protein binding. Dis. Markers 19:1-10.
49. Merchant, M., and S. R. Weinberger. 2000. Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry. Electrophoresis 21: 1164-1167.
50. Miles, L. E., and C. N. Hales. 1968. Labelled antibodies and immunological assay systems. Nature 219:186-189.
51. Miller, J. J., and R. Valdes. 1991. Approaches to minimizing interference by cross-reacting molecules in immunoassays. Clin. Chem. 37:144-153.
52. Niemeyer, C. M., M. Adler, and R. Wacker. 2005. Immuno-PCR: high sensitivity detection of proteins by nucleic acid amplification. Trends Biotechnol. 23:208-216.
53. O'Farrell, P. H. 1975. High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250:4007-4021.
54. Paek, S. H., S. H. Lee, J. H. Cho, and Y. S. Kim. 2000. Development of rapid one-step immunochromatographic assay. Methods 22:53-60.
55. Petricoin, E. E, A. M. Ardekani, B. A. Hitt, P. J. Levine, V. A. Fusaro, S. M. Steinberg, G. B. Mills, C. Simone, D. A. Fishman, E. C. Kohn, and L. A. Liotta. 2002. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359:572-577.
56. Petricoin, E. E, J. Wulfkuhle, V. Espina, and L. A. Liotta. 2004. Clinical proteomics: revolutionizing disease detection and patient tailoring therapy. J. Proteome Res. 3:209-217.
57. Pettersson, K., Y.-Q. Ding, and I. Huhtaniemi. 1991. Monoclonal antibody-based discrepancies between two-site immunometric tests for lutropin. Clin. Chem. 37:1745-1748.
58. Pieper, R., C. L. Gatlin, A. J. Makusky, E S. Russo, C. R. Schatz, S. S. Miller, Q. Su, A. M. McGrath, M. A. Estock, P. P. Parmar, M. Zhao, S. T. Huang, J. Zhou, F. Wang, R. Esquer-Blasco, N. L. Anderson, J. Taylor, and S. Steiner. 2003. The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins. Proteomics 3:1345-1364.
59. Pieper, R., Q. Su, C. L. Gatlin, S. T. Huang, N. L. Anderson, and S. Steiner. 2003. Multi-component immunoaffinity subtraction chromatography: an innovative step towards a comprehensive survey of the human plasma proteome. Proteomics 3:422-432.
60. Piwnica-Worms, D., D. P. Schuster, and J. R. Garbow. 2004. Molecular imaging of host-pathogen interactions in intact small animals. Cell. Microbiol. 6:319-331.
61. Ransohoff, D. F. 2005. Lessons from controversy: ovarian cancer screening and serum proteomics. J. Natl. Cancer Inst. 97:315-319.
62. Rich, R. L., and D. G. Myszka. 2000. Advances in surface plasmon resonance biosensor analysis. Curr. Opin. Biotechnol. 11:54-61.
63. Ritchie, R. E, C. A. Alper, and J. A. Graves. 1969. Experience with a fully automated system for immunoassay of specific serum proteins. Arthritis Rheum. 12:693-699.
64. Rosenblatt, K. P., P. Bryant-Greenwood, J. K. Killian, A. Mehta, D. Geho, V. Espina, E. F. Petricoin III, and L. A. Liotta. 2004. Serum proteomics in cancer diagnosis and management. Annu. Rev. Med. 55:97-112.
65. Rubenstein, K. E., R. S. Schneider, and E. F. Ullman. 1972. "Homogeneous" enzyme immunoassay. A new immunochemical technique. Biochem. Biophys. Res. Commun. 47:846-851.
66. Selby, C. 1999. Interference in immunoassay. Ann. Clin. Biochem. 36:704-721.
67. Self, C. H. 1985. Enzyme amplification-a general method applied to provide an immunoassisted assay for placental alkaline phosphatase. J. Immunol. Methods 76:389-393.
68. Semmes, O. J., Z. Feng, B.-L. Adam, L. L. Banez, D. Campos, L. H. Cazares, D. W. Chan, W. E. Grizzle, E. Izbicka, J. Kagan, G. Malik, D. McLerran, J. W. Moul, A. Partin, P. Prasanna, J. Rosenzweig, L. J. Sokoll, S. Srivastava, S. Srivastava, I. Thompson, M. J. Welsh, N. White, M. Winget, Y. Yasui, Z. Zhang, and L. Zhu. 2005. Evaluation of serum protein profiling by surface- enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer. I. Assessment of platform reproducibility. Clin. Chem. 51:102-112.
69. Sokoll, L. J., F. H. Wians, Jr., and A. T. Remaley. 2004. Rapid intraoperative immunoassay of parathyroid hormone and other hormones: a new paradigm for point-of-care testing. Clin. Chem. 50:1126-1135.
70. Tiselius, A. 1937. A new apparatus for electrophoresis: analysis of colloidal mixtures. Trans. Faraday Soc. 33:524-529.
71. Tribbick, G. 2002. Multipin peptide libraries for antibody and receptor epitope screening and characterization. J. Immunol. Methods 267:27-35.
72. Villanueva, J., J. Philip, D. Entenberg, C. A. Chaparro, M. K. Tanwar, E. C. Holland, and P. Tempst. 2004. Serum peptide profiling by magnetic particle-assisted, automated sample processing and MALDI-TOF mass spectrometry. Anal. Chem. 76:1560-1570.
73. Wang, H., and S. Hanash. 2003. Multi-dimensional liquid phase separations in proteomics. J. Chromatogr. B 787:11-18.
74. Wheeler, M. J. 2001. Automated immunoassay analysers. Ann. Clin. Biochem. 38:217-229.
75. Whicher, J. T., C. P. Price, and K. Spencer. 1983. Immunonephelometric and immunoturbidimetric assays for proteins. Crit. Rev. Clin. Lab. Sci. 18:213-260.
76. Winzor, D. J. 2003. Analytical exclusion chromatography. J. Biochem. Biophys. Methods 30:15-52.
77. Woodhead, J. S., G. M. Addison, and C. N. Hales. 1974. Radioimmunoassay and saturation analysis. The immunoradiometric assay and related techniques. Br. Med. Bull. 30: 44-49.
78. Wu, J. T. 2000. Quantitative Immunoassays: a Practical Guide for Assay Establishment, Troubleshooting, and Clinical Application. AACC Press, Washington, D.C.
79. Yalow, R. S., and S. A. Berson. 1959. Assay of plasma insulin in human subjects by immunological methods. Nature 184:1648-1649.