-
1
-
-
0035012803
-
The epidemiology of rheumatoid arthritis
-
COI: 1:STN:280:DC%2BD3MzivVKguw%3D%3D, PID: 11396092
-
Gabriel SE. The epidemiology of rheumatoid arthritis. Rheum Dis Clin North Am. 2001;27:269–81.
-
(2001)
Rheum Dis Clin North Am
, vol.27
, pp. 269-281
-
-
Gabriel, S.E.1
-
2
-
-
84906827120
-
Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets
-
COI: 1:CAS:528:DC%2BC2sXns1ehtL0%3D
-
Furst DE, Emery P. Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets. Rheumatology (Oxford). 2014;53:1560–9.
-
(2014)
Rheumatology (Oxford)
, vol.53
, pp. 1560-1569
-
-
Furst, D.E.1
Emery, P.2
-
3
-
-
78650679617
-
Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives
-
PID: 21109513
-
Kitas GD, Gabriel SE. Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives. Ann Rheum Dis. 2011;70:8–14.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 8-14
-
-
Kitas, G.D.1
Gabriel, S.E.2
-
4
-
-
3242886819
-
Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD2cXlt1Wltr8%3D
-
Nell VP, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS. Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford). 2004;43:906–14.
-
(2004)
Rheumatology (Oxford)
, vol.43
, pp. 906-914
-
-
Nell, V.P.1
Machold, K.P.2
Eberl, G.3
Stamm, T.A.4
Uffmann, M.5
Smolen, J.S.6
-
5
-
-
77956036473
-
2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
-
PID: 20699241
-
Aletaha D, Neogi T, Silman AJ, et al. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2010;69:1580–8.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1580-1588
-
-
Aletaha, D.1
Neogi, T.2
Silman, A.J.3
-
6
-
-
84877634558
-
Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study
-
PID: 22798566
-
Gremese E, Salaffi F, Bosello SL, et al. Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study. Ann Rheum Dis. 2013;72:858–62.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 858-862
-
-
Gremese, E.1
Salaffi, F.2
Bosello, S.L.3
-
7
-
-
85019702082
-
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
-
PID: 28264816
-
Smolen JS, Landewe R, Bijlsma J, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update. Ann Rheum Dis. 2017;76:960–77.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 960-977
-
-
Smolen, J.S.1
Landewe, R.2
Bijlsma, J.3
-
8
-
-
38149057526
-
Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial
-
COI: 1:CAS:528:DC%2BD1cXhslOjsbY%3D, PID: 18163521
-
Braun J, Kastner P, Flaxenberg P, et al. Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial. Arthritis Rheum. 2008;58:73–81.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 73-81
-
-
Braun, J.1
Kastner, P.2
Flaxenberg, P.3
-
9
-
-
84937727375
-
Effectiveness, tolerability, and safety of subcutaneous methotrexate in early rheumatoid arthritis: a retrospective analysis of real-world data from the St. Gallen cohort
-
COI: 1:CAS:528:DC%2BC2MXmslGguro%3D, PID: 25895697
-
Muller RB, von Kempis J, Haile SR, Schiff MH. Effectiveness, tolerability, and safety of subcutaneous methotrexate in early rheumatoid arthritis: a retrospective analysis of real-world data from the St. Gallen cohort. Semin Arthritis Rheum. 2015;45:28–34.
-
(2015)
Semin Arthritis Rheum
, vol.45
, pp. 28-34
-
-
Muller, R.B.1
von Kempis, J.2
Haile, S.R.3
Schiff, M.H.4
-
10
-
-
84956767541
-
2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis
-
PID: 26545940
-
Singh JA, Saag KG, Bridges SL Jr, et al. 2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Rheumatol. 2016;68:1–26.
-
(2016)
Arthritis Rheumatol
, vol.68
, pp. 1-26
-
-
Singh, J.A.1
Saag, K.G.2
Bridges, S.L.3
-
11
-
-
84893772728
-
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update
-
COI: 1:CAS:528:DC%2BC2cXmsFWkurk%3D, PID: 24161836
-
Smolen JS, Landewe R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis. 2014;73:492–509.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 492-509
-
-
Smolen, J.S.1
Landewe, R.2
Breedveld, F.C.3
-
12
-
-
84871813585
-
Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: findings of a phase IIIb, multinational, prospective, randomized study
-
COI: 1:CAS:528:DC%2BC3sXmslyg, PID: 23169319
-
Weinblatt ME, Schiff M, Valente R, et al. Head-to-head comparison of subcutaneous abatacept versus adalimumab for rheumatoid arthritis: findings of a phase IIIb, multinational, prospective, randomized study. Arthritis Rheum. 2013;65:28–38.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 28-38
-
-
Weinblatt, M.E.1
Schiff, M.2
Valente, R.3
-
13
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
PID: 22873531
-
van Vollenhoven RF, Fleischmann R, Cohen S, et al. Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Engl J Med. 2012;367:508–19.
-
(2012)
N Engl J Med
, vol.367
, pp. 508-519
-
-
van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
-
14
-
-
85003681006
-
Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study
-
COI: 1:CAS:528:DC%2BC28XhvVKgtbjE, PID: 27863807
-
Smolen JS, Burmester GR, Combe B, et al. Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study. Lancet. 2016;388:2763–74.
-
(2016)
Lancet
, vol.388
, pp. 2763-2774
-
-
Smolen, J.S.1
Burmester, G.R.2
Combe, B.3
-
15
-
-
84893721202
-
Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2cXmsFWku7o%3D, PID: 24399231
-
Nam JL, Ramiro S, Gaujoux-Viala C, et al. Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2014;73:516–28.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 516-528
-
-
Nam, J.L.1
Ramiro, S.2
Gaujoux-Viala, C.3
-
16
-
-
84902372533
-
Indispensable or intolerable? Methotrexate in patients with rheumatoid and psoriatic arthritis: a retrospective review of discontinuation rates from a large UK cohort
-
PID: 24609758
-
Nikiphorou E, Negoescu A, Fitzpatrick JD, et al. Indispensable or intolerable? Methotrexate in patients with rheumatoid and psoriatic arthritis: a retrospective review of discontinuation rates from a large UK cohort. Clin Rheumatol. 2014;33:609–14.
-
(2014)
Clin Rheumatol
, vol.33
, pp. 609-614
-
-
Nikiphorou, E.1
Negoescu, A.2
Fitzpatrick, J.D.3
-
17
-
-
85020942844
-
Assessing methotrexate adherence in rheumatoid arthritis: a cross-sectional survey
-
PID: 27747496
-
DiBenedetti DB, Zhou X, Reynolds M, Ogale S, Best JH. Assessing methotrexate adherence in rheumatoid arthritis: a cross-sectional survey. Rheumatol Ther. 2015;2:73–84.
-
(2015)
Rheumatol Ther
, vol.2
, pp. 73-84
-
-
DiBenedetti, D.B.1
Zhou, X.2
Reynolds, M.3
Ogale, S.4
Best, J.H.5
-
18
-
-
79952359578
-
Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register
-
PID: 21330639
-
Soliman MM, Ashcroft DM, Watson KD, Lunt M, Symmons DP, Hyrich KL. Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Ann Rheum Dis. 2011;70:583–9.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 583-589
-
-
Soliman, M.M.1
Ashcroft, D.M.2
Watson, K.D.3
Lunt, M.4
Symmons, D.P.5
Hyrich, K.L.6
-
19
-
-
34249796662
-
Adalimumab alone and in combination with disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis in clinical practice: the Research in Active Rheumatoid Arthritis (ReAct) trial
-
COI: 1:CAS:528:DC%2BD2sXntlOnu7Y%3D, PID: 17329305
-
Burmester GR, Mariette X, Montecucco C, et al. Adalimumab alone and in combination with disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis in clinical practice: the Research in Active Rheumatoid Arthritis (ReAct) trial. Ann Rheum Dis. 2007;66:732–9.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 732-739
-
-
Burmester, G.R.1
Mariette, X.2
Montecucco, C.3
-
20
-
-
85016252656
-
Tofacitinib in combination with conventional disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: patient-reported outcomes from a phase III randomized controlled trial
-
COI: 1:CAS:528:DC%2BC2sXltVSrsLs%3D
-
Strand V, Kremer JM, Gruben D, Krishnaswami S, Zwillich SH, Wallenstein GV. Tofacitinib in combination with conventional disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: patient-reported outcomes from a phase III randomized controlled trial. Arthritis Care Res (Hoboken). 2017;69:592–8.
-
(2017)
Arthritis Care Res (Hoboken)
, vol.69
, pp. 592-598
-
-
Strand, V.1
Kremer, J.M.2
Gruben, D.3
Krishnaswami, S.4
Zwillich, S.H.5
Wallenstein, G.V.6
-
21
-
-
77950862612
-
Comparison of combination therapies in the treatment of rheumatoid arthritis: leflunomide-anti-TNF-alpha versus methotrexate-anti-TNF-alpha
-
PID: 20082236
-
De Stefano R, Frati E, Nargi F, et al. Comparison of combination therapies in the treatment of rheumatoid arthritis: leflunomide-anti-TNF-alpha versus methotrexate-anti-TNF-alpha. Clin Rheumatol. 2010;29:517–24.
-
(2010)
Clin Rheumatol
, vol.29
, pp. 517-524
-
-
De Stefano, R.1
Frati, E.2
Nargi, F.3
-
22
-
-
84926671951
-
Comparative Effectiveness of Tocilizumab with either Methotrexate or Leflunomide in the Treatment of Rheumatoid Arthritis
-
PID: 25830224
-
Narvaez J, Diaz-Torne C, Magallares B, et al. Comparative effectiveness of tocilizumab with either methotrexate or leflunomide in the treatment of rheumatoid arthritis. PLoS One. 2015;10:e0123392.
-
(2015)
PLOS ONE
, vol.10
, Issue.4
-
-
Narváez, J.1
Díaz-Torné, C.2
Magallares, B.3
Hernández, M.V.4
Reina, D.5
Corominas, H.6
Sanmartí, R.7
de la Serna, A.R.8
Llobet, J.M.9
Nolla, J.M.10
-
23
-
-
73449118587
-
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
-
COI: 1:CAS:528:DC%2BC3cXhtFOls78%3D
-
Jones G, Sebba A, Gu J, et al. Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study. Ann Rheum Dis. 2010;69:88–96.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 88-96
-
-
Jones, G.1
Sebba, A.2
Gu, J.3
-
24
-
-
84877275257
-
Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial
-
COI: 1:CAS:528:DC%2BC3sXksFantLw%3D, PID: 23515142
-
Gabay C, Emery P, van Vollenhoven R, et al. Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial. Lancet. 2013;381:1541–50.
-
(2013)
Lancet
, vol.381
, pp. 1541-1550
-
-
Gabay, C.1
Emery, P.2
van Vollenhoven, R.3
-
25
-
-
84925538740
-
Comparison of tocilizumab as monotherapy or with add-on disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and inadequate responses to previous treatments: an open-label study close to clinical practice
-
PID: 25604316
-
Bykerk VP, Ostor AJ, Alvaro-Gracia J, et al. Comparison of tocilizumab as monotherapy or with add-on disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and inadequate responses to previous treatments: an open-label study close to clinical practice. Clin Rheumatol. 2015;34:563–71.
-
(2015)
Clin Rheumatol
, vol.34
, pp. 563-571
-
-
Bykerk, V.P.1
Ostor, A.J.2
Alvaro-Gracia, J.3
-
26
-
-
84871093047
-
Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)
-
COI: 1:CAS:528:DC%2BC3sXitFaqsL4%3D, PID: 22562983
-
Dougados M, Kissel K, Sheeran T, et al. Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY). Ann Rheum Dis. 2013;72:43–50.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 43-50
-
-
Dougados, M.1
Kissel, K.2
Sheeran, T.3
-
27
-
-
84897971056
-
Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study
-
COI: 1:CAS:528:DC%2BC2cXps1Cksrk%3D, PID: 24473673
-
Dougados M, Kissel K, Conaghan PG, et al. Clinical, radiographic and immunogenic effects after 1 year of tocilizumab-based treatment strategies in rheumatoid arthritis: the ACT-RAY study. Ann Rheum Dis. 2014;73:803–9.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 803-809
-
-
Dougados, M.1
Kissel, K.2
Conaghan, P.G.3
-
28
-
-
85020718307
-
Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial
-
COI: 1:CAS:528:DC%2BC1cXhvFOitr3N, PID: 28389552
-
Burmester GR, Rigby WF, van Vollenhoven RF, et al. Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial. Ann Rheum Dis. 2017;76:1279–84.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 1279-1284
-
-
Burmester, G.R.1
Rigby, W.F.2
van Vollenhoven, R.F.3
-
29
-
-
84956630876
-
Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study)
-
COI: 1:CAS:528:DC%2BC1cXhtlSktrc%3D, PID: 26733110
-
Kaneko Y, Atsumi T, Tanaka Y, et al. Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study). Ann Rheum Dis. 2016;75:1917–23.
-
(2016)
Ann Rheum Dis
, vol.75
, pp. 1917-1923
-
-
Kaneko, Y.1
Atsumi, T.2
Tanaka, Y.3
-
30
-
-
85014083376
-
Baricitinib, methotrexate, or combination in patients with rheumatoid arthritis and no or limited prior disease-modifying antirheumatic drug treatment
-
COI: 1:CAS:528:DC%2BC2sXjsVOmtLc%3D, PID: 27723271
-
Fleischmann R, Schiff M, Van der HD, et al. Baricitinib, methotrexate, or combination in patients with rheumatoid arthritis and no or limited prior disease-modifying antirheumatic drug treatment. Arthritis Rheumatol. 2017;69:506–17.
-
(2017)
Arthritis Rheumatol
, vol.69
, pp. 506-517
-
-
Fleischmann, R.1
Schiff, M.2
Van der, H.D.3
-
31
-
-
84991087156
-
Efficacy of tofacitinib in patients with rheumatoid arthritis stratified by background methotrexate dose group
-
COI: 1:STN:280:DC%2BC2svps1Kguw%3D%3D, PID: 27734232
-
Fleischmann R, Mease PJ, Schwartzman S, et al. Efficacy of tofacitinib in patients with rheumatoid arthritis stratified by background methotrexate dose group. Clin Rheumatol. 2017;36:15–24.
-
(2017)
Clin Rheumatol
, vol.36
, pp. 15-24
-
-
Fleischmann, R.1
Mease, P.J.2
Schwartzman, S.3
-
32
-
-
84937630522
-
Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis
-
PID: 25975452
-
Singh JA, Cameron C, Noorbaloochi S, et al. Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis. Lancet. 2015;386:258–65.
-
(2015)
Lancet
, vol.386
, pp. 258-265
-
-
Singh, J.A.1
Cameron, C.2
Noorbaloochi, S.3
-
33
-
-
80053566154
-
Treatment benefit or survival of the fittest: what drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient?
-
COI: 1:CAS:528:DC%2BC3MXhsFamsL3L, PID: 21791449
-
Strangfeld A, Eveslage M, Schneider M, et al. Treatment benefit or survival of the fittest: what drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient? Ann Rheum Dis. 2011;70:1914–20.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1914-1920
-
-
Strangfeld, A.1
Eveslage, M.2
Schneider, M.3
-
34
-
-
85111784785
-
-
June
-
RABBIT Risk Score of Infections. http://www.biologika-register.de/en/home/risk-score/. Accessed 23 June 2017.
-
(2017)
-
-
-
35
-
-
84941168307
-
Risk of infection with biologic antirheumatic therapies in patients with rheumatoid arthritis
-
PID: 26362745
-
Lahiri M, Dixon WG. Risk of infection with biologic antirheumatic therapies in patients with rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2015;29:290–305.
-
(2015)
Best Pract Res Clin Rheumatol
, vol.29
, pp. 290-305
-
-
Lahiri, M.1
Dixon, W.G.2
-
36
-
-
47949106400
-
Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
-
COI: 1:CAS:528:DC%2BD1cXhtVSktbvJ, PID: 18055472
-
Schiff M, Keiserman M, Codding C, et al. Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate. Ann Rheum Dis. 2008;67:1096–103.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1096-1103
-
-
Schiff, M.1
Keiserman, M.2
Codding, C.3
-
37
-
-
84935001577
-
Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy
-
COI: 1:CAS:528:DC%2BC28XitFKqtrrO, PID: 24608404
-
Yun H, Xie F, Delzell E, et al. Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy. Ann Rheum Dis. 2015;74:1065–71.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 1065-1071
-
-
Yun, H.1
Xie, F.2
Delzell, E.3
-
38
-
-
0038755661
-
Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
-
COI: 1:CAS:528:DC%2BD3sXkslKgtrs%3D, PID: 12796126
-
Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT. Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation. 2003;107:3133–40.
-
(2003)
Circulation
, vol.107
, pp. 3133-3140
-
-
Chung, E.S.1
Packer, M.2
Lo, K.H.3
Fasanmade, A.A.4
Willerson, J.T.5
-
39
-
-
11144355760
-
Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL)
-
COI: 1:CAS:528:DC%2BD2cXisFOqtr4%3D, PID: 15023878
-
Mann DL, McMurray JJ, Packer M, et al. Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL). Circulation. 2004;109:1594–602.
-
(2004)
Circulation
, vol.109
, pp. 1594-1602
-
-
Mann, D.L.1
McMurray, J.J.2
Packer, M.3
-
40
-
-
84885190017
-
Heart failure risk among patients with rheumatoid arthritis starting a TNF antagonist
-
COI: 1:CAS:528:DC%2BC3sXhslymsbzK, PID: 23155221
-
Solomon DH, Rassen JA, Kuriya B, et al. Heart failure risk among patients with rheumatoid arthritis starting a TNF antagonist. Ann Rheum Dis. 2013;72:1813–8.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 1813-1818
-
-
Solomon, D.H.1
Rassen, J.A.2
Kuriya, B.3
-
41
-
-
84901789226
-
Biologic therapies in rheumatoid arthritis and the risk of opportunistic infections: a meta-analysis
-
PID: 24647016
-
Kourbeti IS, Ziakas PD, Mylonakis E. Biologic therapies in rheumatoid arthritis and the risk of opportunistic infections: a meta-analysis. Clin Infect Dis. 2014;58:1649–57.
-
(2014)
Clin Infect Dis
, vol.58
, pp. 1649-1657
-
-
Kourbeti, I.S.1
Ziakas, P.D.2
Mylonakis, E.3
-
42
-
-
34249007153
-
Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis
-
COI: 1:CAS:528:DC%2BD2sXms1Ogtrg%3D, PID: 17471434
-
Plessner HL, Lin PL, Kohno T, et al. Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis. J Infect Dis. 2007;195:1643–50.
-
(2007)
J Infect Dis
, vol.195
, pp. 1643-1650
-
-
Plessner, H.L.1
Lin, P.L.2
Kohno, T.3
-
43
-
-
67650096563
-
Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: the three-year prospective French Research Axed on Tolerance of Biotherapies registry
-
COI: 1:CAS:528:DC%2BD1MXptlKktLo%3D, PID: 19565495
-
Tubach F, Salmon D, Ravaud P, et al. Risk of tuberculosis is higher with anti-tumor necrosis factor monoclonal antibody therapy than with soluble tumor necrosis factor receptor therapy: the three-year prospective French Research Axed on Tolerance of Biotherapies registry. Arthritis Rheum. 2009;60:1884–94.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1884-1894
-
-
Tubach, F.1
Salmon, D.2
Ravaud, P.3
-
44
-
-
34547768152
-
Abatacept treatment does not exacerbate chronic Mycobacterium tuberculosis infection in mice
-
COI: 1:CAS:528:DC%2BD2sXhtVWqu7vE, PID: 17665452
-
Bigbee CL, Gonchoroff DG, Vratsanos G, Nadler SG, Haggerty HG, Flynn JL. Abatacept treatment does not exacerbate chronic Mycobacterium tuberculosis infection in mice. Arthritis Rheum. 2007;56:2557–65.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2557-2565
-
-
Bigbee, C.L.1
Gonchoroff, D.G.2
Vratsanos, G.3
Nadler, S.G.4
Haggerty, H.G.5
Flynn, J.L.6
-
45
-
-
84941588323
-
Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2sXivV2qsbc%3D, PID: 26318385
-
Winthrop KL, Park SH, Gul A, et al. Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis. Ann Rheum Dis. 2016;75:1133–8.
-
(2016)
Ann Rheum Dis
, vol.75
, pp. 1133-1138
-
-
Winthrop, K.L.1
Park, S.H.2
Gul, A.3
-
46
-
-
79952013541
-
Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials
-
COI: 1:CAS:528:DC%2BC3MXis1Cgsbg%3D
-
Campbell L, Chen C, Bhagat SS, Parker RA, Ostor AJ. Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials. Rheumatology (Oxford). 2011;50:552–62.
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 552-562
-
-
Campbell, L.1
Chen, C.2
Bhagat, S.S.3
Parker, R.A.4
Ostor, A.J.5
-
47
-
-
84903447241
-
Effect of methotrexate, anti-tumor necrosis factor alpha, and rituximab on the immune response to influenza and pneumococcal vaccines in patients with rheumatoid arthritis: a systematic review and meta-analysis
-
COI: 1:CAS:528:DC%2BC2cXhtVOgtrnM
-
Hua C, Barnetche T, Combe B, Morel J. Effect of methotrexate, anti-tumor necrosis factor alpha, and rituximab on the immune response to influenza and pneumococcal vaccines in patients with rheumatoid arthritis: a systematic review and meta-analysis. Arthritis Care Res (Hoboken). 2014;66:1016–26.
-
(2014)
Arthritis Care Res (Hoboken)
, vol.66
, pp. 1016-1026
-
-
Hua, C.1
Barnetche, T.2
Combe, B.3
Morel, J.4
-
48
-
-
85028283541
-
Effect of methotrexate discontinuation on efficacy of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial
-
Park JK, Lee MA, Lee EY, et al. Effect of methotrexate discontinuation on efficacy of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial. Ann Rheum Dis. doi:10.1136/annrheumdis-2017-211128.
-
(2017)
Annals of the Rheumatic Diseases
, vol.76
, Issue.9
, pp. 1559-1565
-
-
Park, J.K.1
Lee, M.A.2
Lee, E.Y.3
Song, Y.W.4
Choi, Y.5
Winthrop, K.L.6
Lee, E.B.7
-
49
-
-
84929600615
-
The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2sXptVemsA%3D%3D, PID: 25795907
-
Winthrop KL, Silverfield J, Racewicz A, et al. The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis. Ann Rheum Dis. 2016;75:687–95.
-
(2016)
Ann Rheum Dis
, vol.75
, pp. 687-695
-
-
Winthrop, K.L.1
Silverfield, J.2
Racewicz, A.3
-
50
-
-
84880134524
-
Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tocilizumab therapy
-
COI: 1:CAS:528:DC%2BC2cXjtVensrs%3D, PID: 23345600
-
Mori S, Ueki Y, Akeda Y, et al. Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tocilizumab therapy. Ann Rheum Dis. 2013;72:1362–6.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 1362-1366
-
-
Mori, S.1
Ueki, Y.2
Akeda, Y.3
-
51
-
-
84978805792
-
Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional synthetic DMARDs
-
COI: 1:STN:280:DC%2BC2s3gtVCgtg%3D%3D, PID: 27405509
-
Strangfeld A, Richter A, Siegmund B, et al. Risk for lower intestinal perforations in patients with rheumatoid arthritis treated with tocilizumab in comparison to treatment with other biologic or conventional synthetic DMARDs. Ann Rheum Dis. 2017;76:504–10.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 504-510
-
-
Strangfeld, A.1
Richter, A.2
Siegmund, B.3
-
52
-
-
84978983306
-
Risk of invasive melanoma in patients with rheumatoid arthritis treated with biologics: results from a collaborative project of 11 European biologic registers
-
Mercer LK, Askling J, Raaschou P, et al. Risk of invasive melanoma in patients with rheumatoid arthritis treated with biologics: results from a collaborative project of 11 European biologic registers. Ann Rheum Dis. 2017;76:386–91.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 386-391
-
-
Mercer, L.K.1
Askling, J.2
Raaschou, P.3
-
53
-
-
84893803131
-
Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2cXmsFWku7g%3D, PID: 24401994
-
Ramiro S, Gaujoux-Viala C, Nam JL, et al. Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis. Ann Rheum Dis. 2014;73:529–35.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 529-535
-
-
Ramiro, S.1
Gaujoux-Viala, C.2
Nam, J.L.3
-
54
-
-
33749365296
-
Safety of the selective costimulation modulator abatacept in rheumatoid arthritis patients receiving background biologic and nonbiologic disease-modifying antirheumatic drugs: a 1-year randomized, placebo-controlled study
-
COI: 1:CAS:528:DC%2BD28XhtFWksLjJ, PID: 16947384
-
Weinblatt M, Combe B, Covucci A, Aranda R, Becker JC, Keystone E. Safety of the selective costimulation modulator abatacept in rheumatoid arthritis patients receiving background biologic and nonbiologic disease-modifying antirheumatic drugs: a 1-year randomized, placebo-controlled study. Arthritis Rheum. 2006;54:2807–16.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2807-2816
-
-
Weinblatt, M.1
Combe, B.2
Covucci, A.3
Aranda, R.4
Becker, J.C.5
Keystone, E.6
-
55
-
-
2342551979
-
Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate
-
COI: 1:CAS:528:DC%2BD2cXkvFykurw%3D, PID: 15146410
-
Genovese MC, Cohen S, Moreland L, et al. Combination therapy with etanercept and anakinra in the treatment of patients with rheumatoid arthritis who have been treated unsuccessfully with methotrexate. Arthritis Rheum. 2004;50:1412–9.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1412-1419
-
-
Genovese, M.C.1
Cohen, S.2
Moreland, L.3
-
56
-
-
79953718761
-
Evaluation of the safety of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis: results from a randomized controlled trial
-
COI: 1:CAS:528:DC%2BC3MXksFWrsr8%3D, PID: 21360491
-
Greenwald MW, Shergy WJ, Kaine JL, Sweetser MT, Gilder K, Linnik MD. Evaluation of the safety of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis: results from a randomized controlled trial. Arthritis Rheum. 2011;63:622–32.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 622-632
-
-
Greenwald, M.W.1
Shergy, W.J.2
Kaine, J.L.3
Sweetser, M.T.4
Gilder, K.5
Linnik, M.D.6
-
57
-
-
84934914576
-
Rituximab versus an alternative TNF inhibitor in patients with rheumatoid arthritis who failed to respond to a single previous TNF inhibitor: SWITCH-RA, a global, observational, comparative effectiveness study
-
COI: 1:CAS:528:DC%2BC28XitFKqtrrN, PID: 24442884
-
Emery P, Gottenberg JE, Rubbert-Roth A, et al. Rituximab versus an alternative TNF inhibitor in patients with rheumatoid arthritis who failed to respond to a single previous TNF inhibitor: SWITCH-RA, a global, observational, comparative effectiveness study. Ann Rheum Dis. 2015;74:979–84.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 979-984
-
-
Emery, P.1
Gottenberg, J.E.2
Rubbert-Roth, A.3
-
58
-
-
34248545097
-
B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents
-
PID: 17469098
-
Finckh A, Ciurea A, Brulhart L, et al. B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents. Arthritis Rheum. 2007;56:1417–23.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1417-1423
-
-
Finckh, A.1
Ciurea, A.2
Brulhart, L.3
-
59
-
-
34447319146
-
Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice
-
COI: 1:CAS:528:DC%2BD2sXosVSjt74%3D
-
Bombardieri S, Ruiz AA, Fardellone P, et al. Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice. Rheumatology (Oxford). 2007;46:1191–9.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 1191-1199
-
-
Bombardieri, S.1
Ruiz, A.A.2
Fardellone, P.3
-
60
-
-
79955650444
-
Clinical relevance of switching to a second tumour necrosis factor-alpha inhibitor after discontinuation of a first tumour necrosis factor-alpha inhibitor in rheumatoid arthritis: a systematic literature review and meta-analysis
-
PID: 21269578
-
Remy A, Avouac J, Gossec L, Combe B. Clinical relevance of switching to a second tumour necrosis factor-alpha inhibitor after discontinuation of a first tumour necrosis factor-alpha inhibitor in rheumatoid arthritis: a systematic literature review and meta-analysis. Clin Exp Rheumatol. 2011;29:96–103.
-
(2011)
Clin Exp Rheumatol
, vol.29
, pp. 96-103
-
-
Remy, A.1
Avouac, J.2
Gossec, L.3
Combe, B.4
-
61
-
-
67650379733
-
Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial
-
COI: 1:CAS:528:DC%2BD1MXos12ru7o%3D, PID: 19560810
-
Smolen JS, Kay J, Doyle MK, et al. Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial. Lancet. 2009;374:210–21.
-
(2009)
Lancet
, vol.374
, pp. 210-221
-
-
Smolen, J.S.1
Kay, J.2
Doyle, M.K.3
-
62
-
-
80755132171
-
Outcomes of switching anti-TNF drugs in rheumatoid arthritis—a study based on observational data from the Finnish Register of Biological Treatment (ROB-FIN)
-
PID: 21644062
-
Virkki LM, Valleala H, Takakubo Y, et al. Outcomes of switching anti-TNF drugs in rheumatoid arthritis—a study based on observational data from the Finnish Register of Biological Treatment (ROB-FIN). Clin Rheumatol. 2011;30:1447–54.
-
(2011)
Clin Rheumatol
, vol.30
, pp. 1447-1454
-
-
Virkki, L.M.1
Valleala, H.2
Takakubo, Y.3
-
63
-
-
84922243078
-
Rheumatoid arthritis secondary non-responders to TNF can attain an efficacious and safe response by switching to certolizumab pegol: a phase IV, randomised, multicentre, double-blind, 12-week study, followed by a 12-week open-label phase
-
COI: 1:CAS:528:DC%2BC2MXislWnsg%3D%3D, PID: 24972708
-
Schiff MH, von Kempis J, Goldblum R, Tesser JR, Mueller RB. Rheumatoid arthritis secondary non-responders to TNF can attain an efficacious and safe response by switching to certolizumab pegol: a phase IV, randomised, multicentre, double-blind, 12-week study, followed by a 12-week open-label phase. Ann Rheum Dis. 2014;73:2174–7.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 2174-2177
-
-
Schiff, M.H.1
von Kempis, J.2
Goldblum, R.3
Tesser, J.R.4
Mueller, R.B.5
-
64
-
-
84892529958
-
The role of DMARDs in reducing the immunogenicity of TNF inhibitors in chronic inflammatory diseases
-
COI: 1:CAS:528:DC%2BC2cXhtVOhtL8%3D
-
Jani M, Barton A, Warren RB, Griffiths CE, Chinoy H. The role of DMARDs in reducing the immunogenicity of TNF inhibitors in chronic inflammatory diseases. Rheumatology (Oxford). 2014;53:213–22.
-
(2014)
Rheumatology (Oxford)
, vol.53
, pp. 213-222
-
-
Jani, M.1
Barton, A.2
Warren, R.B.3
Griffiths, C.E.4
Chinoy, H.5
-
65
-
-
24944498854
-
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
-
COI: 1:CAS:528:DC%2BD2MXhtVWhsbnI, PID: 16162882
-
Genovese MC, Becker JC, Schiff M, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005;353:1114–23.
-
(2005)
N Engl J Med
, vol.353
, pp. 1114-1123
-
-
Genovese, M.C.1
Becker, J.C.2
Schiff, M.3
-
66
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
COI: 1:CAS:528:DC%2BD28XhtFWksLjI, PID: 16947627
-
Cohen SB, Emery P, Greenwald MW, et al. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum. 2006;54:2793–806.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
-
67
-
-
77955896561
-
Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab’s Efficacy in MTX iNadequate rEsponders (SERENE))
-
COI: 1:CAS:528:DC%2BC3cXhtFyit7%2FI, PID: 20488885
-
Emery P, Deodhar A, Rigby WF, et al. Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab’s Efficacy in MTX iNadequate rEsponders (SERENE)). Ann Rheum Dis. 2010;69:1629–35.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1629-1635
-
-
Emery, P.1
Deodhar, A.2
Rigby, W.F.3
-
68
-
-
77951777466
-
Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: results from the SUNRISE trial
-
COI: 1:CAS:528:DC%2BC3cXnsFOrsrY%3D, PID: 20194448
-
Mease PJ, Cohen S, Gaylis NB, et al. Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: results from the SUNRISE trial. J Rheumatol. 2010;37:917–27.
-
(2010)
J Rheumatol
, vol.37
, pp. 917-927
-
-
Mease, P.J.1
Cohen, S.2
Gaylis, N.B.3
-
69
-
-
84868484220
-
Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: a large, open-label study close to clinical practice
-
COI: 1:CAS:528:DC%2BC3sXosVKhsw%3D%3D, PID: 22615456
-
Bykerk VP, Ostor AJ, Alvaro-Gracia J, et al. Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: a large, open-label study close to clinical practice. Ann Rheum Dis. 2012;71:1950–4.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 1950-1954
-
-
Bykerk, V.P.1
Ostor, A.J.2
Alvaro-Gracia, J.3
-
70
-
-
52149099504
-
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
-
COI: 1:CAS:528:DC%2BD1cXhtl2gsbbI, PID: 18625622
-
Emery P, Keystone E, Tony HP, et al. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann Rheum Dis. 2008;67:1516–23.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1516-1523
-
-
Emery, P.1
Keystone, E.2
Tony, H.P.3
-
71
-
-
84873707288
-
Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial
-
COI: 1:CAS:528:DC%2BC3sXkvFOqsw%3D%3D, PID: 23294500
-
Burmester GR, Blanco R, Charles-Schoeman C, et al. Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial. Lancet. 2013;381:451–60.
-
(2013)
Lancet
, vol.381
, pp. 451-460
-
-
Burmester, G.R.1
Blanco, R.2
Charles-Schoeman, C.3
-
72
-
-
84962375370
-
Baricitinib in patients with refractory rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC28Xht1Kisr3E, PID: 27028914
-
Genovese MC, Kremer J, Zamani O, et al. Baricitinib in patients with refractory rheumatoid arthritis. N Engl J Med. 2016;374:1243–52.
-
(2016)
N Engl J Med
, vol.374
, pp. 1243-1252
-
-
Genovese, M.C.1
Kremer, J.2
Zamani, O.3
-
73
-
-
58349113392
-
Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials
-
COI: 1:STN:280:DC%2BD1M%2FhtlOrsg%3D%3D, PID: 18203761
-
Salliot C, Dougados M, Gossec L. Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials. Ann Rheum Dis. 2009;68:25–32.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 25-32
-
-
Salliot, C.1
Dougados, M.2
Gossec, L.3
-
74
-
-
84871016290
-
Rituximab (RTX) as an alternative to TNF-alpha antagonists in patients with rheumatoid arthritis and high risk of severe infections: a systematic analysis of the experience in one center
-
COI: 1:CAS:528:DC%2BC38Xhs1eqtbjI, PID: 23002410
-
Xanthouli P, Sailer S, Fiehn C. Rituximab (RTX) as an alternative to TNF-alpha antagonists in patients with rheumatoid arthritis and high risk of severe infections: a systematic analysis of the experience in one center. Open Rheumatol J. 2012;6:286–9.
-
(2012)
Open Rheumatol J
, vol.6
, pp. 286-289
-
-
Xanthouli, P.1
Sailer, S.2
Fiehn, C.3
-
75
-
-
84881475884
-
Long-term safety of rituximab in rheumatoid arthritis: 9.5-year follow-up of the global clinical trial programme with a focus on adverse events of interest in RA patients
-
PID: 23136242
-
van Vollenhoven RF, Emery P, Bingham CO III, et al. Long-term safety of rituximab in rheumatoid arthritis: 9.5-year follow-up of the global clinical trial programme with a focus on adverse events of interest in RA patients. Ann Rheum Dis. 2013;72:1496–502.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 1496-1502
-
-
van Vollenhoven, R.F.1
Emery, P.2
Bingham, C.O.3
-
76
-
-
85013393351
-
Baricitinib versus placebo or adalimumab in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC2sXhtlyktbvK, PID: 28199814
-
Taylor PC, Keystone EC, Van der HD, et al. Baricitinib versus placebo or adalimumab in rheumatoid arthritis. N Engl J Med. 2017;376:652–62.
-
(2017)
N Engl J Med
, vol.376
, pp. 652-662
-
-
Taylor, P.C.1
Keystone, E.C.2
Van der, H.D.3
-
77
-
-
85021855305
-
Risk of serious adverse effects of biological and targeted drugs in patients with rheumatoid arthritis: a systematic review meta-analysis
-
COI: 1:CAS:528:DC%2BC1cXitFKgsbzO
-
Tarp S, Eric FD, Boers M, et al. Risk of serious adverse effects of biological and targeted drugs in patients with rheumatoid arthritis: a systematic review meta-analysis. Rheumatology (Oxford). 2017;56:417–25.
-
(2017)
Rheumatology (Oxford)
, vol.56
, pp. 417-425
-
-
Tarp, S.1
Eric, F.D.2
Boers, M.3
-
78
-
-
70449709528
-
The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: the ARRIVE trial
-
COI: 1:CAS:528:DC%2BD1MXhs1WitbfN, PID: 19074911
-
Schiff M, Pritchard C, Huffstutter JE, et al. The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: the ARRIVE trial. Ann Rheum Dis. 2009;68:1708–14.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1708-1714
-
-
Schiff, M.1
Pritchard, C.2
Huffstutter, J.E.3
-
79
-
-
84954317028
-
Efficacy and safety of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional DMARDs in patients with RA at week 97 (SUMMACTA)
-
COI: 1:CAS:528:DC%2BC28XhsVektL3J, PID: 26056119
-
Burmester GR, Rubbert-Roth A, Cantagrel A, et al. Efficacy and safety of subcutaneous tocilizumab versus intravenous tocilizumab in combination with traditional DMARDs in patients with RA at week 97 (SUMMACTA). Ann Rheum Dis. 2016;75:68–74.
-
(2016)
Ann Rheum Dis
, vol.75
, pp. 68-74
-
-
Burmester, G.R.1
Rubbert-Roth, A.2
Cantagrel, A.3
-
80
-
-
84963491033
-
Change from subcutaneous to intravenous abatacept and back in patients with rheumatoid arthritis as simulation of a vacation: a prospective phase IV, open-label trial (A-BREAK)
-
Mueller RB, Gengenbacher M, Richter S, Dudler J, Moller B, von Kempis J. Change from subcutaneous to intravenous abatacept and back in patients with rheumatoid arthritis as simulation of a vacation: a prospective phase IV, open-label trial (A-BREAK). Arthritis Res Ther. 2016;18:88.
-
(2016)
Arthritis Res Ther
, vol.18
-
-
Mueller, R.B.1
Gengenbacher, M.2
Richter, S.3
Dudler, J.4
Moller, B.5
von Kempis, J.6
-
81
-
-
45149128195
-
Patient self-injection of methotrexate for inflammatory arthritis: a study evaluating the introduction of a new type of syringe and exploring patients’ sense of empowerment
-
Hiley J, Homer D, Clifford C. Patient self-injection of methotrexate for inflammatory arthritis: a study evaluating the introduction of a new type of syringe and exploring patients’ sense of empowerment. Musculoskelet Care. 2008;6:15–30.
-
(2008)
Musculoskelet Care
, vol.6
, pp. 15-30
-
-
Hiley, J.1
Homer, D.2
Clifford, C.3
-
82
-
-
85010871775
-
Sarilumab and nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis and inadequate response or intolerance to tumor necrosis factor inhibitors
-
COI: 1:CAS:528:DC%2BC2sXhslWrsLY%3D, PID: 27860410
-
Fleischmann R, van Adelsberg J, Lin Y, et al. Sarilumab and nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis and inadequate response or intolerance to tumor necrosis factor inhibitors. Arthritis Rheumatol. 2017;69:277–90.
-
(2017)
Arthritis Rheumatol
, vol.69
, pp. 277-290
-
-
Fleischmann, R.1
van Adelsberg, J.2
Lin, Y.3
-
83
-
-
84929881847
-
Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a phase III study
-
COI: 1:CAS:528:DC%2BC2MXpt1Wqs7c%3D, PID: 25733246
-
Genovese MC, Fleischmann R, Kivitz AJ, et al. Sarilumab plus methotrexate in patients with active rheumatoid arthritis and inadequate response to methotrexate: results of a phase III study. Arthritis Rheumatol. 2015;67:1424–37.
-
(2015)
Arthritis Rheumatol
, vol.67
, pp. 1424-1437
-
-
Genovese, M.C.1
Fleischmann, R.2
Kivitz, A.J.3
-
84
-
-
85019144284
-
Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial
-
COI: 1:CAS:528:DC%2BC1cXnt1WitLw%3D, PID: 27856432
-
Burmester GR, Lin Y, Patel R, et al. Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial. Ann Rheum Dis. 2017;76:840–7.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 840-847
-
-
Burmester, G.R.1
Lin, Y.2
Patel, R.3
-
85
-
-
85011115927
-
A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate
-
COI: 1:CAS:528:DC%2BC1cXnt1Witbw%3D, PID: 28087506
-
Smolen JS, Agarwal SK, Ilivanova E, et al. A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate. Ann Rheum Dis. 2017;76:831–9.
-
(2017)
Ann Rheum Dis
, vol.76
, pp. 831-839
-
-
Smolen, J.S.1
Agarwal, S.K.2
Ilivanova, E.3
-
86
-
-
84895465850
-
One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study
-
COI: 1:CAS:528:DC%2BC2cXotlOitLg%3D, PID: 24429175
-
Genovese MC, Durez P, Richards HB, et al. One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study. J Rheumatol. 2014;41:414–21.
-
(2014)
J Rheumatol
, vol.41
, pp. 414-421
-
-
Genovese, M.C.1
Durez, P.2
Richards, H.B.3
-
87
-
-
84886226230
-
A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis
-
PID: 24286136
-
Martin DA, Churchill M, Flores-Suarez L, et al. A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis. Arthritis Res Ther. 2013;15:R164.
-
(2013)
Arthritis Res Ther
, vol.15
, pp. R164
-
-
Martin, D.A.1
Churchill, M.2
Flores-Suarez, L.3
-
88
-
-
84903478179
-
A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors
-
COI: 1:CAS:528:DC%2BC2cXhsVCiu73L, PID: 24623718
-
Genovese MC, Greenwald M, Cho CS, et al. A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors. Arthritis Rheumatol. 2014;66:1693–704.
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 1693-1704
-
-
Genovese, M.C.1
Greenwald, M.2
Cho, C.S.3
-
89
-
-
85020791952
-
-
Accessed 23 June 2017
-
Generics and Biosimilars Initiative Online. Biosimilars approved in Europe. 2017. http://www.gabionline.net/Biosimilars/General/Biosimilars-approved-in-Europe. Accessed 23 June 2017.
-
(2017)
Biosimilars approved in Europe
-
-
-
91
-
-
84874983369
-
Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trial
-
COI: 1:CAS:528:DC%2BC3sXhtFKqs74%3D, PID: 23332236
-
Smolen JS, Nash P, Durez P, et al. Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trial. Lancet. 2013;381:918–29.
-
(2013)
Lancet
, vol.381
, pp. 918-929
-
-
Smolen, J.S.1
Nash, P.2
Durez, P.3
-
92
-
-
84928023549
-
Disease activity guided dose reduction and withdrawal of adalimumab or etanercept compared with usual care in rheumatoid arthritis: open label, randomised controlled, non-inferiority trial
-
PID: 25858265
-
van Herwaarden N, Van der MA, Minten MJ, et al. Disease activity guided dose reduction and withdrawal of adalimumab or etanercept compared with usual care in rheumatoid arthritis: open label, randomised controlled, non-inferiority trial. BMJ. 2015;350:h1389.
-
(2015)
BMJ
, vol.350
, pp. h1389
-
-
van Herwaarden, N.1
Van der, M.A.2
Minten, M.J.3
-
93
-
-
84917726540
-
Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study
-
COI: 1:CAS:528:DC%2BC2MXitFCiu7o%3D, PID: 25169728
-
Huizinga TW, Conaghan PG, Martin-Mola E, et al. Clinical and radiographic outcomes at 2 years and the effect of tocilizumab discontinuation following sustained remission in the second and third year of the ACT-RAY study. Ann Rheum Dis. 2015;74:35–43.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 35-43
-
-
Huizinga, T.W.1
Conaghan, P.G.2
Martin-Mola, E.3
-
94
-
-
84926623879
-
Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BC2MXhtFCmtr3E, PID: 24431394
-
Smolen JS, Emery P, Ferraccioli GF, et al. Certolizumab pegol in rheumatoid arthritis patients with low to moderate activity: the CERTAIN double-blind, randomised, placebo-controlled trial. Ann Rheum Dis. 2015;74:843–50.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 843-850
-
-
Smolen, J.S.1
Emery, P.2
Ferraccioli, G.F.3
-
95
-
-
84877634558
-
Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study
-
PID: 22798566
-
Gremese E, Salaffi F, Bosello SL, et al. Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study. Ann Rheum Dis. 2013;72:858–62.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 858-862
-
-
Gremese, E.1
Salaffi, F.2
Bosello, S.L.3
-
96
-
-
33750717549
-
Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: The BeSt study
-
Allaart CF, Goekoop-Ruiterman YP, Vries-Bouwstra JK, Breedveld FC, Dijkmans BA. Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study. Clin Exp Rheumatol. 2006;24:S-82.
-
(2006)
Clin Exp Rheumatol
, pp. S-82
-
-
Allaart, C.F.1
Goekoop-Ruiterman, Y.P.2
Vries-Bouwstra, J.K.3
Breedveld, F.C.4
Dijkmans, B.A.5
-
97
-
-
0037231533
-
Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial
-
COI: 1:CAS:528:DC%2BD3sXhtFGnsb0%3D, PID: 12528101
-
Weinblatt ME, Keystone EC, Furst DE, et al. Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum. 2003;48:35–45.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 35-45
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
-
98
-
-
2342658406
-
Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial
-
COI: 1:CAS:528:DC%2BD2cXkvFykur4%3D, PID: 15146409
-
Keystone EC, Kavanaugh AF, Sharp JT, et al. Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum. 2004;50:1400–11.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1400-1411
-
-
Keystone, E.C.1
Kavanaugh, A.F.2
Sharp, J.T.3
-
99
-
-
55849112632
-
Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a 52 week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
-
COI: 1:CAS:528:DC%2BD1cXhsV2hs7nM, PID: 18975346
-
Keystone E, Heijde D, Mason D Jr, et al. Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a 52 week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum. 2008;58:3319–29.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3319-3329
-
-
Keystone, E.1
Heijde, D.2
Mason, D.3
-
100
-
-
67449124634
-
Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial
-
COI: 1:CAS:528:DC%2BD1MXotVCjtLo%3D, PID: 19015207
-
Smolen J, Landewe RB, Mease P, et al. Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial. Ann Rheum Dis. 2009;68:797–804.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 797-804
-
-
Smolen, J.1
Landewe, R.B.2
Mease, P.3
-
101
-
-
0033574147
-
Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial
-
COI: 1:CAS:528:DyaK1MXitFChs7Y%3D, PID: 10075615
-
Moreland LW, Schiff MH, Baumgartner SW, et al. Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann Intern Med. 1999;130:478–86.
-
(1999)
Ann Intern Med
, vol.130
, pp. 478-486
-
-
Moreland, L.W.1
Schiff, M.H.2
Baumgartner, S.W.3
-
102
-
-
42449157502
-
Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: a randomized, double-blind, placebo-controlled, dose-ranging study
-
COI: 1:CAS:528:DC%2BD1cXltFGisbw%3D, PID: 18383539
-
Kay J, Matteson EL, Dasgupta B, et al. Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: a randomized, double-blind, placebo-controlled, dose-ranging study. Arthritis Rheum. 2008;58:964–75.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 964-975
-
-
Kay, J.1
Matteson, E.L.2
Dasgupta, B.3
-
103
-
-
67449133560
-
Golimumab, a human antibody to tumour necrosis factor alpha given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD study
-
COI: 1:CAS:528:DC%2BD1MXotVCjtL0%3D, PID: 19066176
-
Keystone EC, Genovese MC, Klareskog L, et al. Golimumab, a human antibody to tumour necrosis factor alpha given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD study. Ann Rheum Dis. 2009;68:789–96.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 789-796
-
-
Keystone, E.C.1
Genovese, M.C.2
Klareskog, L.3
-
104
-
-
0033524159
-
Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group
-
COI: 1:CAS:528:DC%2BD3cXit1Oquw%3D%3D, PID: 10622295
-
Maini R, St Clair EW, Breedveld F, et al. Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet. 1999;354:1932–9.
-
(1999)
Lancet
, vol.354
, pp. 1932-1939
-
-
Maini, R.1
St Clair, E.W.2
Breedveld, F.3
-
105
-
-
30144442293
-
A multicenter, double-blind, randomized, placebo controlled trial of infliximab combined with low dose methotrexate in Japanese patients with rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD28Xps1ajug%3D%3D, PID: 16395748
-
Abe T, Takeuchi T, Miyasaka N, et al. A multicenter, double-blind, randomized, placebo controlled trial of infliximab combined with low dose methotrexate in Japanese patients with rheumatoid arthritis. J Rheumatol. 2006;33:37–44.
-
(2006)
J Rheumatol
, vol.33
, pp. 37-44
-
-
Abe, T.1
Takeuchi, T.2
Miyasaka, N.3
-
106
-
-
33745291091
-
Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial
-
COI: 1:CAS:528:DC%2BD28XntF2jsr8%3D, PID: 16785475
-
Kremer JM, Genant HK, Moreland LW, et al. Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med. 2006;144:865–76.
-
(2006)
Ann Intern Med
, vol.144
, pp. 865-876
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
-
107
-
-
23644455857
-
Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase IIb, double-blind, randomized, placebo-controlled trial
-
COI: 1:CAS:528:DC%2BD2MXpslGhtr4%3D, PID: 16052582
-
Kremer JM, Dougados M, Emery P, et al. Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase IIb, double-blind, randomized, placebo-controlled trial. Arthritis Rheum. 2005;52:2263–71.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2263-2271
-
-
Kremer, J.M.1
Dougados, M.2
Emery, P.3
-
108
-
-
2942537697
-
Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD2cXkvFKntrc%3D, PID: 15201414
-
Edwards JC, Szczepanski L, Szechinski J, et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med. 2004;350:2572–81.
-
(2004)
N Engl J Med
, vol.350
, pp. 2572-2581
-
-
Edwards, J.C.1
Szczepanski, L.2
Szechinski, J.3
-
109
-
-
33646483031
-
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
-
COI: 1:CAS:528:DC%2BD28XlsFSquro%3D, PID: 16649186
-
Emery P, Fleischmann R, Filipowicz-Sosnowska A, et al. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum. 2006;54:1390–400.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1390-1400
-
-
Emery, P.1
Fleischmann, R.2
Filipowicz-Sosnowska, A.3
-
110
-
-
40749114497
-
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
-
COI: 1:CAS:528:DC%2BD1cXjs1Sltbc%3D, PID: 18358926
-
Smolen JS, Beaulieu A, Rubbert-Roth A, et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet. 2008;371:987–97.
-
(2008)
Lancet
, vol.371
, pp. 987-997
-
-
Smolen, J.S.1
Beaulieu, A.2
Rubbert-Roth, A.3
-
111
-
-
33749363027
-
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
-
COI: 1:CAS:528:DC%2BD28XhtFWksLjK, PID: 16947782
-
Maini RN, Taylor PC, Szechinski J, et al. Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum. 2006;54:2817–29.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2817-2829
-
-
Maini, R.N.1
Taylor, P.C.2
Szechinski, J.3
-
112
-
-
84874402383
-
Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four-month phase III randomized radiographic study
-
van der Heijde, Tanaka Y, Fleischmann R, et al. Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: twelve-month data from a twenty-four-month phase III randomized radiographic study. Arthritis Rheum. 2013;65:559–570.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 559-570
-
-
van Der Heijde, T.Y.1
Fleischmann, R.2
-
113
-
-
84921475867
-
Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate
-
COI: 1:CAS:528:DC%2BC2MXksVSltbc%3D, PID: 25431052
-
Keystone EC, Taylor PC, Drescher E, et al. Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate. Ann Rheum Dis. 2015;74:333–40.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 333-340
-
-
Keystone, E.C.1
Taylor, P.C.2
Drescher, E.3
|