Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: A large, open-label study close to clinical practice

Annals of the Rheumatic Diseases

Volumn 71, Issue 12, 2012, Pages 1950-1954

  Bykerk, Vivian P ^a,b   Östör, Andrew J K ^c   Alvaro Gracia, Jos ^d   Pavelka, Karel ^e   Ivorra, Jos Andrs Romn ^f   Graninger, Winfried ^g   Bensen, William ^h   Nurmohamed, Michael T ⁱ   Krause, Andreas ^j   Bernasconi, Corrado ^k   Stancati, Andrea ^l   Sibilia, Jean ^m  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^e CHARLES UNIVERSITY   (Czech Republic)

^f HOSPITAL UNIVERSITARIO LA FE   (Spain)

^g MEDICAL UNIVERSITY OF GRAZ   (Austria)

^h MCMASTER UNIVERSITY   (Canada)

ⁱ VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^j Medical Centre for Rheumatology Berlin Buch   (Germany)

^k Biostatistics   (Switzerland)

^l Global Medical Affairs   (Switzerland)

^m HÔPITAL DE HAUTEPIERRE   (France)

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Author keywords

[No Author keywords available]

Indexed keywords

EID: 84868484220     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-201087     Document Type: Article

References (15)

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3. Smolen JS, Beaulieu A, Rubbert-Roth A, et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet 2008;371:987-97.
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5. Genovese MC, McKay JD, Nasonov EL, et al. Interleukin-6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease-modifying antirheumatic drugs: the tocilizumab in combination with traditional disease-modifying antirheumatic drug therapy study. Arthritis Rheum 2008;58:2968-80.
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