SARS-CoV-2: A storm is raging

Journal of Clinical Investigation

Volumn 130, Issue 5, 2020, Pages 2202-2205

  Pedersen, Savannah F ^a   Ho, Ya Chi ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; VIRUS VACCINE;

CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL FEATURE; CLINICAL OUTCOME; COMMON COLD; CORONAVIRUS DISEASE 2019; CYTOKINE PRODUCTION; CYTOKINE STORM; DISEASE ASSOCIATION; DISEASE SEVERITY; HOSPITAL ADMISSION; HUMAN; IMMUNOLOGICAL PARAMETERS; IMMUNOTHERAPY; LYMPHOCYTOPENIA; NONHUMAN; PANDEMIC; PRIORITY JOURNAL; RESPIRATORY DISTRESS; REVIEW; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VACCINATION;

EID: 85083161939     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI137647     Document Type: Review

References (19)

1. Huang C, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.
2. Zhu N, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-733.
3. Chan JF, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514-523.
4. Li Q, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. NEnglJMed. 2020;382(13):1199-1207.
5. van Doremalen N, et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 [published online March 17, 2020]. N Engl J Med. https://doi.org/10.1056/nejmc2004973.
6. Rothe C, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med. 2020;382(10):970-971.
7. Bai Y, et al. Presumed asymptomatic carrier transmission of COVID-19 [published online February 21, 2020]. Jama. https://doi.org/10.1001/jama.2020.2565.
8. Li R, et al. Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) [published online March 16, 2020]. Science. https://doi.org/10.1126/science.abb3221.
9. Peiris JS, Yuen KY, Osterhaus AD, Stöhr K. The severe acute respiratory syndrome. N Engl J Med. 2003;349(25):2431-2441.
10. Graham RL, Donaldson EF, Baric RS. A decade after SARS: strategies for controlling emerging coronaviruses. Nat Rev Microbiol. 2013;11(12):836-848.
11. Lu R, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395(10224):565-574.
12. Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 [published online March 4, 2020]. Science. https://doi.org/10.1126/science.abb2762.
13. Guan WJ, et al. Clinical characteristics of coronavirus disease 2019 in China [published online February 28, 2020]. N Engl J Med. https://doi.org/10.1056/nejmoa2002032.
14. WHO. Coronavirus disease 2019 (COVID-19) Situation Report - 46. https://www.who.int/docs/default-source/coronaviruse/ situation-reports/20200306-sitrep-46-covid-19.pdf. Updated March 6, 2020. Accessed March 27, 2020.
15. Chen G, et al. Clinical and immunological features of severe and moderate coronavirus disease 2019. J Clin Invest. 2020;130(5):2620-2629.
16. Channappanavar R, Perlman S. Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Semin Immunopathol. 2017;39(5):529-539.
17. Channappanavar R, et al. Dysregulated type I interferon and inflammatory monocytemacrophage responses cause lethal pneumonia in SARS-CoV-infected mice. Cell Host Microbe. 2016;19(2):181-193.
18. Diao B, et al. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19). medRxiv. 2020:2020.02.18.20024364. Posted on medRxiv February 20, 2020. https://doi.org/10. 1101/2020.02.18.20024364.
19. Liao M, et al. The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing [preprint]. Posted on medRxiv February 26, 2020. https://doi.org/10.1101/2020.02.23.20026690.