-
1
-
-
33748748732
-
Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy
-
Agoram B, Heatherington AC, Gastonguay MR (2006) Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy. AAPS J 8(3):E552-E563.
-
(2006)
AAPS J
, vol.8
, Issue.3
-
-
Agoram, B.1
Heatherington, A.C.2
Gastonguay, M.R.3
-
2
-
-
34848915402
-
A data integration approach for cell cycle analysis oriented to model simulation in systems biology
-
doi:10.1186/1752-0509-1-35
-
Alfieri R, Merelli I, Mosca E, Milanesi L (2007) A data integration approach for cell cycle analysis oriented to model simulation in systems biology. BMC Syst Biol. doi:10.1186/1752-0509-1-35.
-
(2007)
BMC Syst Biol
-
-
Alfieri, R.1
Merelli, I.2
Mosca, E.3
Milanesi, L.4
-
3
-
-
0002833130
-
Conceptual frameworks for mathematical modeling of tumor growth dynamics
-
Bajzer Z, Marusic M, Vuk-Pavlocic S (1996) Conceptual frameworks for mathematical modeling of tumor growth dynamics. Math Comput Model 23:31-46.
-
(1996)
Math Comput Model
, vol.23
, pp. 31-46
-
-
Bajzer, Z.1
Marusic, M.2
Vuk-Pavlocic, S.3
-
4
-
-
67449092662
-
Predictive modelling in hormone-refractory prostate cancer (HRPC)
-
Bellmunt J, Carles J, Albanell J (2009) Predictive modelling in hormone-refractory prostate cancer (HRPC). Clin Translat Oncol 11:82-85.
-
(2009)
Clin Translat Oncol
, vol.11
, pp. 82-85
-
-
Bellmunt, J.1
Carles, J.2
Albanell, J.3
-
5
-
-
33644700937
-
Survival and prognostic factors in BRCA1-associated breast cancer
-
Brekelmans CT, Seynaeve C, Menke-Pluymers M, Brüggenwirth HT, Tilanus-Linthorst MM, Bartels CC, Kriege M, van Geel AN, Crepin CM, Blom JC, Meijers-Heijboer H, Klijn JG (2006) Survival and prognostic factors in BRCA1-associated breast cancer. Ann Oncol 17:391-400.
-
(2006)
Ann Oncol
, vol.17
, pp. 391-400
-
-
Brekelmans, C.T.1
Seynaeve, C.2
Menke-Pluymers, M.3
Brüggenwirth, H.T.4
Tilanus-Linthorst, M.M.5
Bartels, C.C.6
Kriege, M.7
van Geel, A.N.8
Crepin, C.M.9
Blom, J.C.10
Meijers-Heijboer, H.11
Klijn, J.G.12
-
6
-
-
33847668823
-
Tumor characteristics, survival and prognostic factors of hereditary breast cancer from BRCA2-, BRCA1- and non-BRCA1/2 families as compared to sporadic breast cancer cases
-
Brekelmans CT, Tilanus-Linthorst MM, Seynaeve C, vd Ouweland A, Menke-Pluymers MB, Bartels CC, Kriege M, van Geel AN, Burger CW, Eggermont AM, Meijers-Heijboer H, Klijn JG (2007) Tumor characteristics, survival and prognostic factors of hereditary breast cancer from BRCA2-, BRCA1- and non-BRCA1/2 families as compared to sporadic breast cancer cases. Eur J Cancer 43:867-876.
-
(2007)
Eur J Cancer
, vol.43
, pp. 867-876
-
-
Brekelmans, C.T.1
Tilanus-Linthorst, M.M.2
Seynaeve, C.3
Ouweland, A.4
Menke-Pluymers, M.B.5
Bartels, C.C.6
Kriege, M.7
van Geel, A.N.8
Burger, C.W.9
Eggermont, A.M.10
Meijers-Heijboer, H.11
Klijn, J.G.12
-
7
-
-
37849186485
-
Approaches to biosimulation of cellular processes
-
Bruggeman FJ, Westerhoff HV (2006) Approaches to biosimulation of cellular processes. J Biol Phys 32:273-288.
-
(2006)
J Biol Phys
, vol.32
, pp. 273-288
-
-
Bruggeman, F.J.1
Westerhoff, H.V.2
-
8
-
-
67651162021
-
On the use of change in tumor size to predict survival in clinical oncology studies: Toward a new paradigm to design and evaluate phase II studies
-
Bruno R, Claret L (2009) On the use of change in tumor size to predict survival in clinical oncology studies: toward a new paradigm to design and evaluate phase II studies. Clin Pharmacol Ther 86(2):136-138.
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.2
, pp. 136-138
-
-
Bruno, R.1
Claret, L.2
-
9
-
-
63949087251
-
Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients
-
Bulitta JB, Zhao P, Arnold RD, Kessler DR, Daifuku R, Pratt J, Luciano G, Hanauske AR, Gelderblom H, Awada A, Jusko WJ (2009) Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients. Cancer Chemother Pharmacol 63(6):1035-1048.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, Issue.6
, pp. 1035-1048
-
-
Bulitta, J.B.1
Zhao, P.2
Arnold, R.D.3
Kessler, D.R.4
Daifuku, R.5
Pratt, J.6
Luciano, G.7
Hanauske, A.R.8
Gelderblom, H.9
Awada, A.10
Jusko, W.J.11
-
10
-
-
42949145995
-
Evaluation of tumor response, disease control, progression-free survival, and time to progression as potential surrogate end points in metastatic breast cancer
-
Burzykowski T, Buyse M, Piccart-Gebhart MJ, Sledge G, Carmichael J, L̈uck HJ, Mackey JR, Nabholtz JM, Paridaens R, Biganzoli L, Jassem J, Bontenbal M, Bonneterre J, Chan S, Basaran AG, Therasse P (2008) Evaluation of tumor response, disease control, progression-free survival, and time to progression as potential surrogate end points in metastatic breast cancer. J Clin Oncol 26:1987-1992.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1987-1992
-
-
Burzykowski, T.1
Buyse, M.2
Piccart-Gebhart, M.J.3
Sledge, G.4
Carmichael, J.5
Lück, H.J.6
Mackey, J.R.7
Nabholtz, J.M.8
Paridaens, R.9
Biganzoli, L.10
Jassem, J.11
Bontenbal, M.12
Bonneterre, J.13
Chan, S.14
Basaran, A.G.15
Therasse, P.16
-
11
-
-
70350156608
-
Use of meta-analysis for the validation of surrogate endpoints and biomarkers in cancer trials
-
Buyse M (2009) Use of meta-analysis for the validation of surrogate endpoints and biomarkers in cancer trials. Cancer J 15:421-425.
-
(2009)
Cancer J
, vol.15
, pp. 421-425
-
-
Buyse, M.1
-
12
-
-
77953127347
-
Biomarkers and surrogate end points-the challenge of statistical validation
-
Buyse M, Sargent DJ, Grothey A, Matheson A, de Gramont A (2010) Biomarkers and surrogate end points-the challenge of statistical validation. Nat Rev Clin Oncol 7(6):309-317.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.6
, pp. 309-317
-
-
Buyse, M.1
Sargent, D.J.2
Grothey, A.3
Matheson, A.4
de Gramont, A.5
-
13
-
-
0029946895
-
Mathematical modelling of tumor response in primary breast cancer
-
Cameron DA, Gregory WM, Bowman A, Leonard RC (1996) Mathematical modelling of tumor response in primary breast cancer. Br J Cancer 73(11):1409-1416.
-
(1996)
Br J Cancer
, vol.73
, Issue.11
, pp. 1409-1416
-
-
Cameron, D.A.1
Gregory, W.M.2
Bowman, A.3
Leonard, R.C.4
-
14
-
-
34547794152
-
Determination of the optimal therapeutic protocols in cancer immunotherapy
-
Cappuccio A, Castiglione F, Piccoli B (2007) Determination of the optimal therapeutic protocols in cancer immunotherapy. Mathl Biosci 209:1-13.
-
(2007)
Mathl Biosci
, vol.209
, pp. 1-13
-
-
Cappuccio, A.1
Castiglione, F.2
Piccoli, B.3
-
15
-
-
70249104257
-
Cancer metastasis networks and the prediction of progression patterns
-
Chen LL, Blumm N, Christakis NA, Barabási AL, Deisboeck TS (2009) Cancer metastasis networks and the prediction of progression patterns. Br J Cancer 101:749-758.
-
(2009)
Br J Cancer
, vol.101
, pp. 749-758
-
-
Chen, L.L.1
Blumm, N.2
Christakis, N.A.3
Barabási, A.L.4
Deisboeck, T.S.5
-
16
-
-
70249134646
-
Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics
-
Claret L, Girard P, Hoff PM, Van Cutsem E, Zuideveld KP, Jorga K, Fagerberg J, Bruno R (2009) Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics. J Clin Oncol 27(25):4103-4108.
-
(2009)
J Clin Oncol
, vol.27
, Issue.25
, pp. 4103-4108
-
-
Claret, L.1
Girard, P.2
Hoff, P.M.3
van Cutsem, E.4
Zuideveld, K.P.5
Jorga, K.6
Fagerberg, J.7
Bruno, R.8
-
17
-
-
78449281238
-
Cancer therapy beyond apoptosis: Autophagy and anoikis as mechanisms of cell death
-
doi:10.1016/j.jss.2009.07.011
-
Coates JM, Galante JM, Bold RJ (2009) Cancer therapy beyond apoptosis: Autophagy and anoikis as mechanisms of cell death. J Surg Res. doi:10.1016/j.jss.2009.07.011.
-
(2009)
J Surg Res
-
-
Coates, J.M.1
Galante, J.M.2
Bold, R.J.3
-
19
-
-
24044497597
-
Mechanism-based pharmacokinetic- pharmacodynamic modeling-a new classification of biomarkers
-
Danhof M, Alvan G, Dahl SG, Kuhlmann J, Paintaud G (2005) Mechanism-based pharmacokinetic- pharmacodynamic modeling-a new classification of biomarkers. Pharm Res 22 (9):1432-1437.
-
(2005)
Pharm Res
, vol.22
, Issue.9
, pp. 1432-1437
-
-
Danhof, M.1
Alvan, G.2
Dahl, S.G.3
Kuhlmann, J.4
Paintaud, G.5
-
20
-
-
65549100701
-
Tumor burden influences exposure and response to rituximab: Pharmacokinetic- pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20
-
Daydé D, Ternant D, Ohresser M, Lerondel S, Pesnel S, Watier H, Le Pape A, Bardos P, Paintaud G, Cartron G (2009) Tumor burden influences exposure and response to rituximab: pharmacokinetic- pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20. Blood 113(16):3765-3772.
-
(2009)
Blood
, vol.113
, Issue.16
, pp. 3765-3772
-
-
Daydé, D.1
Ternant, D.2
Ohresser, M.3
Lerondel, S.4
Pesnel, S.5
Watier, H.6
Le Pape, A.7
Bardos, P.8
Paintaud, G.9
Cartron, G.10
-
21
-
-
0027769745
-
Comparison of four basic models of indirect pharmacodynamic responses
-
Dayneka NL, Garg V, Jusko WJ (1993) Comparison of four basic models of indirect pharmacodynamic responses. J Pharmacokinet Biopharm 21:457-478
-
(1993)
J Pharmacokinet Biopharm
, vol.21
, pp. 457-478
-
-
Dayneka, N.L.1
Garg, V.2
Jusko, W.J.3
-
22
-
-
67349199539
-
Development and external validation of prognostic model for 2-year survival of non-small-cell lung cancer patients treated with chemoradiotherapy
-
Dehing-Oberije C, Yu S, De Ruysscher D, Meersschout S, Van Beek K, Lievens Y, Van Meerbeeck J, De Neve W, Rao B, van der Weide H, Lambin P (2009) Development and external validation of prognostic model for 2-year survival of non-small-cell lung cancer patients treated with chemoradiotherapy. Int J Radiat Oncol Biol Phys 74(2):355-362
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.74
, Issue.2
, pp. 355-362
-
-
Dehing-Oberije, C.1
Yu, S.2
de Ruysscher, D.3
Meersschout, S.4
van Beek, K.5
Lievens, Y.6
van Meerbeeck, J.7
de Neve, W.8
Rao, B.9
van der Weide, H.10
Lambin, P.11
-
23
-
-
0035030266
-
Pattern of self-organization in tumor systems: Complex growth dynamics in a novel brain tumor spheroid model
-
Deisboeck T (2001) Pattern of self-organization in tumor systems: complex growth dynamics in a novel brain tumor spheroid model. Cell Prolif 34:115-134
-
(2001)
Cell Prolif
, vol.34
, pp. 115-134
-
-
Deisboeck, T.1
-
24
-
-
77950516191
-
The missing link between clinical endpoints and drug targets in depression
-
Della Pasqua O, Santen GW, Danhof M (2010) The missing link between clinical endpoints and drug targets in depression. Trends Pharmacol Sci 31:144-152
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 144-152
-
-
Della Pasqua, O.1
Santen, G.W.2
Danhof, M.3
-
25
-
-
34848894497
-
Modelling spatially correlated survival data for individuals with multiple cancers
-
Diva U, Banerjee S, Dey DK (2007) Modelling spatially correlated survival data for individuals with multiple cancers. Stat Modelling 7:191-213
-
(2007)
Stat Modelling
, vol.7
, pp. 191-213
-
-
Diva, U.1
Banerjee, S.2
Dey, D.K.3
-
26
-
-
0018822793
-
Kinetics of bone marrow cell production in human acute and chronic myeloid leukemias
-
Dormer P, Lau B, Wilmanns W (1980) Kinetics of bone marrow cell production in human acute and chronic myeloid leukemias. Leuk Res 4:231-237
-
(1980)
Leuk Res
, vol.4
, pp. 231-237
-
-
Dormer, P.1
Lau, B.2
Wilmanns, W.3
-
27
-
-
34250370236
-
-
European Medicines Agency. Committee for Medicinal Products for Human Use, (CHMP/ewp/ 205/95 rev.3). Methodological considerations for using progression-free survival (PFS) as primary endpoint in confirmatory trials for registration
-
European Medicines Agency. Committee for Medicinal Products for Human Use (2006) Appendix 1 to the guideline on the evaluation of anticancer medicinal products in man (CHMP/ewp/ 205/95 rev.3). Methodological considerations for using progression-free survival (PFS) as primary endpoint in confirmatory trials for registration. http://www.emea.europa.eu/pdfs/human/ewp/26757506en.pdf
-
(2006)
Appendix 1 to the Guideline On the Evaluation of Anticancer Medicinal Products In Man
-
-
-
28
-
-
53249131199
-
Pharmacokinetic/pharmacodynamic modeling and simulation of neutropenia during phase I development of liposome-entrapped paclitaxel
-
Fetterly GJ, Grasela TH, Sherman JW, Dul JL, Grahn A, Lecomte D, Fiedler-Kelly J, Damjanov N, Fishman M, Kane MP, Rubin EH, Tan AR (2008) Pharmacokinetic/pharmacodynamic modeling and simulation of neutropenia during phase I development of liposome-entrapped paclitaxel. Clin Cancer Res 14(18):5856-5863
-
(2008)
Clin Cancer Res
, vol.14
, Issue.18
, pp. 5856-5863
-
-
Fetterly, G.J.1
Grasela, T.H.2
Sherman, J.W.3
Dul, J.L.4
Grahn, A.5
Lecomte, D.6
Fiedler-Kelly, J.7
Damjanov, N.8
Fishman, M.9
Kane, M.P.10
Rubin, E.H.11
Tan, A.R.12
-
29
-
-
0035999133
-
Critical determinants of metastasis
-
Fidler IJ (2002) Critical determinants of metastasis. Semin Cancer Biol 12(2):89-96
-
(2002)
Semin Cancer Biol
, vol.12
, Issue.2
, pp. 89-96
-
-
Fidler, I.J.1
-
30
-
-
70449397174
-
A statistical model for the dependence between progression-free survival and overall survival
-
Fleischer F, Gaschler-Markefski B, Bluhmki E (2009) A statistical model for the dependence between progression-free survival and overall survival. Stat Med 28:2669-2686
-
(2009)
Stat Med
, vol.28
, pp. 2669-2686
-
-
Fleischer, F.1
Gaschler-Markefski, B.2
Bluhmki, E.3
-
31
-
-
37349051416
-
New strategies in controlling drug resistance in chronic myeloid leukemia
-
Frame D (2007) New strategies in controlling drug resistance in chronic myeloid leukemia. Am J Health Syst Pharm 64:S16-S21
-
(2007)
Am J Health Syst Pharm
, vol.64
-
-
Frame, D.1
-
32
-
-
0038826703
-
Mechanistic models for myelosuppression
-
Friberg LE, Karlsson MO (2003) Mechanistic models for myelosuppression. Invest New Drugs 21:183-194
-
(2003)
Invest New Drugs
, vol.21
, pp. 183-194
-
-
Friberg, L.E.1
Karlsson, M.O.2
-
33
-
-
0033667166
-
Models of schedule dependent haematological toxicity of 2'-deoxy-2'-methylidenecytidine (DMDC)
-
Friberg LE, Brindley CJ, Karlsson MO, Devlin AJ (2000) Models of schedule dependent haematological toxicity of 2'-deoxy-2'-methylidenecytidine (DMDC). Eur J Clin Pharmacol 56:567-574
-
(2000)
Eur J Clin Pharmacol
, vol.56
, pp. 567-574
-
-
Friberg, L.E.1
Brindley, C.J.2
Karlsson, M.O.3
Devlin, A.J.4
-
34
-
-
0037115430
-
Model of chemotherapyinduced myelosuppression with parameter consistency across drugs
-
Friberg LE, Henningsson A, Maas H, Nguyen L, Karlsson MO (2002) Model of chemotherapyinduced myelosuppression with parameter consistency across drugs. J Clin Oncol 20:4713-4721
-
(2002)
J Clin Oncol
, vol.20
, pp. 4713-4721
-
-
Friberg, L.E.1
Henningsson, A.2
Maas, H.3
Nguyen, L.4
Karlsson, M.O.5
-
35
-
-
67650608192
-
Modeling and simulation of the time course of asenapine exposure response and dropout patterns in acute schizophrenia
-
Friberg LE, de Greef R, Kerbusch T, Karlsson MO (2009) Modeling and simulation of the time course of asenapine exposure response and dropout patterns in acute schizophrenia. Clin Pharmacol Ther 86(1):84-91
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.1
, pp. 84-91
-
-
Friberg, L.E.1
de Greef, R.2
Kerbusch, T.3
Karlsson, M.O.4
-
36
-
-
0034163504
-
A mechanistic, predictive model of dose-response curves for cell cycle phasespecific and -nonspecific drugs
-
Gardner SN (2000) A mechanistic, predictive model of dose-response curves for cell cycle phasespecific and -nonspecific drugs. Cancer Res 60:1417-1425
-
(2000)
Cancer Res
, vol.60
, pp. 1417-1425
-
-
Gardner, S.N.1
-
37
-
-
0035110051
-
Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapy
-
Gasparini G, Biganzoli E, Bonoldi E, Morabito A, Fanelli A, Boracchi P (2001) Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapy. Breast Cancer Res Treat 65:71-75
-
(2001)
Breast Cancer Res Treat
, vol.65
, pp. 71-75
-
-
Gasparini, G.1
Biganzoli, E.2
Bonoldi, E.3
Morabito, A.4
Fanelli, A.5
Boracchi, P.6
-
38
-
-
0037352930
-
Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients
-
Gieschke R, Burger HU, Reigner B, Blesch KS, Steimer JL (2003) Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients. Br J Clin Pharmacol 55:252-263
-
(2003)
Br J Clin Pharmacol
, vol.55
, pp. 252-263
-
-
Gieschke, R.1
Burger, H.U.2
Reigner, B.3
Blesch, K.S.4
Steimer, J.L.5
-
39
-
-
33845466196
-
Computational methodologies for modelling, analysis and simulation of signalling networks
-
Gilbert D, Fuss H, Gu X, Orton R, Robinson S, Vyshemirsky V, Kurth MJ, Downes CS, Dubitzky W (2006) Computational methodologies for modelling, analysis and simulation of signalling networks. Brief Bioinform 7:339-353
-
(2006)
Brief Bioinform
, vol.7
, pp. 339-353
-
-
Gilbert, D.1
Fuss, H.2
Gu, X.3
Orton, R.4
Robinson, S.5
Vyshemirsky, V.6
Kurth, M.J.7
Downes, C.S.8
Dubitzky, W.9
-
40
-
-
38149033365
-
Biological systems modeling and analysis: A biomolecular technique of the twenty-first century
-
Goel G, Chou IC, Voit EO (2006) Biological systems modeling and analysis: a biomolecular technique of the twenty-first century. J Biomol Tech 17:252-269
-
(2006)
J Biomol Tech
, vol.17
, pp. 252-269
-
-
Goel, G.1
Chou, I.C.2
Voit, E.O.3
-
41
-
-
2342448515
-
Population pharmacokinetic modelling of Emfilermin (recombinant human leukaemia inhibitory factor, r-hLIF) in healthy postmenopausal women and in infertile patients undergoing in vitro fertilization and embryo transfer
-
Goggin T, Nguyen QT, Munafo A (2004) Population pharmacokinetic modelling of Emfilermin (recombinant human leukaemia inhibitory factor, r-hLIF) in healthy postmenopausal women and in infertile patients undergoing in vitro fertilization and embryo transfer. Br J Clin Pharmacol 57(5):576-585
-
(2004)
Br J Clin Pharmacol
, vol.57
, Issue.5
, pp. 576-585
-
-
Goggin, T.1
Nguyen, Q.T.2
Munafo, A.3
-
43
-
-
0028568315
-
Cell cycle control and cancer
-
Hartwell LH, Kastan MB (1994) Cell cycle control and cancer. Science 266:1821-1828
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
44
-
-
45849095049
-
-
Abstract 929
-
Hénin E, Zuideveld KP, Dartois C, Tranchand B, Freyer G, Girard P (2006) A KPD model for ordered categorical data: application to toxicity score in colorectal cancer patients treated with capecitabine PAGE 15 (2006) Abstract 929. www.page-meeting.org/?abstract1/4929
-
(2006)
A KPD Model For Ordered Categorical Data: Application to Toxicity Score In Colorectal Cancer Patients Treated With Capecitabine
, pp. 15
-
-
Hénin, E.1
Zuideveld, K.P.2
Dartois, C.3
Tranchand, B.4
Freyer, G.5
Girard, P.6
-
45
-
-
37549038238
-
Mechanism-based pharmacokinetic/pharmacodynamic meta-analysis of trabectedin (ET-743, Yondelis) induced neutropenia
-
Hing J, Perez-Ruixo JJ, Stuyckens K, Soto-Matos A, Lopez-Lazaro L, Zannikos P (2008) Mechanism-based pharmacokinetic/pharmacodynamic meta-analysis of trabectedin (ET-743, Yondelis) induced neutropenia. Clin Pharmacol Ther 83:130-143
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 130-143
-
-
Hing, J.1
Perez-Ruixo, J.J.2
Stuyckens, K.3
Soto-Matos, A.4
Lopez-Lazaro, L.5
Zannikos, P.6
-
47
-
-
0001654004
-
Nuclear incorporation of P-32 as demonstrated by autoradiographs
-
Howard A, Pelc SR (1951) Nuclear incorporation of P-32 as demonstrated by autoradiographs. Exp Cell Res 2:178-187
-
(1951)
Exp Cell Res
, vol.2
, pp. 178-187
-
-
Howard, A.1
Pelc, S.R.2
-
48
-
-
77953544231
-
Basic PK/PD principles of drug effects in circular/ proliferative systems for disease modelling
-
Jacqmin P, McFadyen L, Wade JR (2010) Basic PK/PD principles of drug effects in circular/ proliferative systems for disease modelling. J Pharmacokinet Pharmacodyn 37(2):157-177
-
(2010)
J Pharmacokinet Pharmacodyn
, vol.37
, Issue.2
, pp. 157-177
-
-
Jacqmin, P.1
McFadyen, L.2
Wade, J.R.3
-
49
-
-
35948943122
-
Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: A study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group
-
Joerger M, Huitema AD, Richel DJ, Dittrich C, Pavlidis N, Briasoulis E, Vermorken JB, Strocchi E, Martoni A, Sorio R, Sleeboom HP, Izquierdo MA, Jodrell DI, Calvert H, Boddy AV, Hollema H, Fety R, van derVijgh WF, Hempel G, Chatelut E, Karlsson M, Wilkins J, Tranchand B, Schrijvers AHGL, Twelves C, Beijnen JH, Schellens JHM (2007a) Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group. Clin Cancer Res 13:6410-6418
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6410-6418
-
-
Joerger, M.1
Huitema, A.D.2
Richel, D.J.3
Dittrich, C.4
Pavlidis, N.5
Briasoulis, E.6
Vermorken, J.B.7
Strocchi, E.8
Martoni, A.9
Sorio, R.10
Sleeboom, H.P.11
Izquierdo, M.A.12
Jodrell, D.I.13
Calvert, H.14
Boddy, A.V.15
Hollema, H.16
Fety, R.17
van derVijgh, W.F.18
Hempel, G.19
Chatelut, E.20
Karlsson, M.21
Wilkins, J.22
Tranchand, B.23
Schrijvers, A.H.G.L.24
Twelves, C.25
Beijnen, J.H.26
Schellens, J.H.M.27
more..
-
50
-
-
36249031853
-
Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: A study by the EORTC-PAMM-NDDG
-
Joerger M, Huitema AD, Richel DJ et al (2007b) Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG. Clin Pharmacokinet 46:1051-1068
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 1051-1068
-
-
Joerger, M.1
Huitema, A.D.2
Richel, D.J.3
-
51
-
-
0037986306
-
Endpoints and United States Food and Drug Administration approval of oncology drugs
-
Johnson JR, Williams G, Pazdur R (2003) Endpoints and United States Food and Drug Administration approval of oncology drugs. J Clin Oncol 21:1404-1411
-
(2003)
J Clin Oncol
, vol.21
, pp. 1404-1411
-
-
Johnson, J.R.1
Williams, G.2
Pazdur, R.3
-
52
-
-
33644764720
-
Modelling competing risks in cancer studies
-
Klein JP (2006) Modelling competing risks in cancer studies. Stat Med 25:1015-1034
-
(2006)
Stat Med
, vol.25
, pp. 1015-1034
-
-
Klein, J.P.1
-
53
-
-
47149089801
-
Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells
-
Krzyzanski W, Perez-Ruixo JJ, Vermeulen A (2008) Basic pharmacodynamic models for agents that alter the lifespan distribution of natural cells. J Pharmacokinet Pharmacodyn 35(3):349-377
-
(2008)
J Pharmacokinet Pharmacodyn
, vol.35
, Issue.3
, pp. 349-377
-
-
Krzyzanski, W.1
Perez-Ruixo, J.J.2
Vermeulen, A.3
-
54
-
-
0015386298
-
The gross rates of growth of human mammary cancer
-
Kusama S, Spratt JS Jr, Donegan WL, Watson FR, Cunningham C (1972) The gross rates of growth of human mammary cancer. Cancer 30:594-599
-
(1972)
Cancer
, vol.30
, pp. 594-599
-
-
Kusama, S.1
Spratt Jr., J.S.2
Donegan, W.L.3
Watson, F.R.4
Cunningham, C.5
-
55
-
-
0032534995
-
Modeling of the time-dependency of in vitro drug cytotoxicity and resistance
-
Levasseur LM, Slocum HK, Rustum YM, Greco WR (1998) Modeling of the time-dependency of in vitro drug cytotoxicity and resistance. Cancer Res 58:5749-5761
-
(1998)
Cancer Res
, vol.58
, pp. 5749-5761
-
-
Levasseur, L.M.1
Slocum, H.K.2
Rustum, Y.M.3
Greco, W.R.4
-
56
-
-
27644472628
-
Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft
-
Luo FR, Yang Z, Dong H, Camuso A, McGlinchey K, Fager K, Flefleh C, Kan D, Inigo I, Castaneda S, Rose WC, Kramer RA, Wild R, Lee FY (2005) Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft. Cancer Chemother Pharmacol 56:455-464
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, pp. 455-464
-
-
Luo, F.R.1
Yang, Z.2
Dong, H.3
Camuso, A.4
McGlinchey, K.5
Fager, K.6
Flefleh, C.7
Kan, D.8
Inigo, I.9
Castaneda, S.10
Rose, W.C.11
Kramer, R.A.12
Wild, R.13
Lee, F.Y.14
-
57
-
-
0036803408
-
Receptor-mediated pharmacokinetic/pharmacodynamic model of interferon-beta 1a in humans
-
Mager DE, Jusko WJ (2002) Receptor-mediated pharmacokinetic/pharmacodynamic model of interferon-beta 1a in humans. Pharm Res 19:1537-1543
-
(2002)
Pharm Res
, vol.19
, pp. 1537-1543
-
-
Mager, D.E.1
Jusko, W.J.2
-
58
-
-
67649312041
-
Scaling pharmacodynamics from in vitro and preclinical animal studies to humans
-
Mager DE, Woo S, Jusko WJ (2009) Scaling pharmacodynamics from in vitro and preclinical animal studies to humans. Drug Metab Pharmacokinet 24(1):16-24
-
(2009)
Drug Metab Pharmacokinet
, vol.24
, Issue.1
, pp. 16-24
-
-
Mager, D.E.1
Woo, S.2
Jusko, W.J.3
-
59
-
-
33646040109
-
A mathematical model to study the effects of drugs administration on tumor growth dynamics
-
Magni P, Simeoni M, Poggesi I, Rocchetti M, de Nicolao G (2006) A mathematical model to study the effects of drugs administration on tumor growth dynamics. Math Biosci 200:127-151
-
(2006)
Math Biosci
, vol.200
, pp. 127-151
-
-
Magni, P.1
Simeoni, M.2
Poggesi, I.3
Rocchetti, M.4
de Nicolao, G.5
-
60
-
-
0035754079
-
Milestones in cell division: Cell senescence and cancer
-
Mathon NF, Lloyd AC (2001) Milestones in cell division: Cell senescence and cancer. Nature Rev Cancer 1:203-213
-
(2001)
Nature Rev Cancer
, vol.1
, pp. 203-213
-
-
Mathon, N.F.1
Lloyd, A.C.2
-
61
-
-
0001628564
-
On the law of growth in Jensen's rat sarcoma
-
Mayneord WV (1932) On the law of growth in Jensen's rat sarcoma. Am J Cancer 16:841-846
-
(1932)
Am J Cancer
, vol.16
, pp. 841-846
-
-
Mayneord, W.V.1
-
62
-
-
33745918670
-
Mathematical modelling of dynamic adaptive tumor-induced angiogenesis: Clinical implications and therapeutic targeting strategies
-
McDougall SR, Anderson AR, Chaplain MA (2006) Mathematical modelling of dynamic adaptive tumor-induced angiogenesis: clinical implications and therapeutic targeting strategies. J Theor Biol 241:564-589
-
(2006)
J Theor Biol
, vol.241
, pp. 564-589
-
-
McDougall, S.R.1
Anderson, A.R.2
Chaplain, M.A.3
-
63
-
-
75149145545
-
Pharmacokinetics and pharmacodynamics of monoclonal antibodies: Concepts and lessons for drug development
-
Mould DR, Green B (2010) Pharmacokinetics and pharmacodynamics of monoclonal antibodies: concepts and lessons for drug development. Biodrugs 24:23-39
-
(2010)
Biodrugs
, vol.24
, pp. 23-39
-
-
Mould, D.R.1
Green, B.2
-
64
-
-
67651202352
-
A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma
-
Mould DR, Sweeney K, Duffull SB, Neylon E, Hamlin P, Horwitz S, Sirotnak F, Fleisher M, Saunders ME, O'Connor OA (2009) A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma. Clin Pharmacol Ther 86(2):190-196
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.2
, pp. 190-196
-
-
Mould, D.R.1
Sweeney, K.2
Duffull, S.B.3
Neylon, E.4
Hamlin, P.5
Horwitz, S.6
Sirotnak, F.7
Fleisher, M.8
Saunders, M.E.9
O'Connor, O.A.10
-
65
-
-
37349061349
-
Mathematical modelling for the assessment of the effect of drug application delays in metronomic chemotherapy of cancer due to physiological constraints
-
Mukherjee A, Majumder D (2008) Mathematical modelling for the assessment of the effect of drug application delays in metronomic chemotherapy of cancer due to physiological constraints. Biosystems 91:108-116
-
(2008)
Biosystems
, vol.91
, pp. 108-116
-
-
Mukherjee, A.1
Majumder, D.2
-
66
-
-
70449720511
-
Dynamics of target-mediated drug disposition
-
Peletier LA, Gabrielsson J (2009) Dynamics of target-mediated drug disposition. Eur J Pharm Sci 38(5):445-464
-
(2009)
Eur J Pharm Sci
, vol.38
, Issue.5
, pp. 445-464
-
-
Peletier, L.A.1
Gabrielsson, J.2
-
68
-
-
40049096141
-
The association of dropout and outcome in trials of antipsychotic medication and its implications for dealing with missing data
-
Rabinowitz J, Davidov O (2008) The association of dropout and outcome in trials of antipsychotic medication and its implications for dealing with missing data. Schizophr Bull 34(2):286-291
-
(2008)
Schizophr Bull
, vol.34
, Issue.2
, pp. 286-291
-
-
Rabinowitz, J.1
Davidov, O.2
-
69
-
-
16544380415
-
Phase II studies of modern drugs directed against new targets: If you are fazed, too, then resist RECIST
-
Ratain MJ, Eckhardt SG (2004) Phase II studies of modern drugs directed against new targets: if you are fazed, too, then resist RECIST. J Clin Oncol 22(22):4442-4445
-
(2004)
J Clin Oncol
, vol.22
, Issue.22
, pp. 4442-4445
-
-
Ratain, M.J.1
Eckhardt, S.G.2
-
70
-
-
0033957112
-
Modelling in tumor biology part 1: Modelling concepts and structures
-
Rew DA (2000a) Modelling in tumor biology part 1: modelling concepts and structures. Eur J Surg Oncol 26:87-94
-
(2000)
Eur J Surg Oncol
, vol.26
, pp. 87-94
-
-
Rew, D.A.1
-
71
-
-
0034061987
-
Modelling in tumor biology part II: Modelling cancer therapy
-
Rew DA (2000b) Modelling in tumor biology part II: modelling cancer therapy. Eur J Surg Oncol 26:181-188
-
(2000)
Eur J Surg Oncol
, vol.26
, pp. 181-188
-
-
Rew, D.A.1
-
72
-
-
0034109745
-
Cell production rates in human tissues and tumors and their significance. Part 1: An introduction to the techniques of measurement and their limitations
-
Rew DA, Wilson GD (2000a) Cell production rates in human tissues and tumors and their significance. Part 1: an introduction to the techniques of measurement and their limitations. Eur J Surg Oncol 26:227-238
-
(2000)
Eur J Surg Oncol
, vol.26
, pp. 227-238
-
-
Rew, D.A.1
Wilson, G.D.2
-
73
-
-
0033940198
-
Cell production rates in human tissues and tumors and their significance. Part II: Clinical data
-
Rew DA, Wilson GD (2000b) Cell production rates in human tissues and tumors and their significance. Part II: clinical data. Eur J Surg Oncol 26:405-417
-
(2000)
Eur J Surg Oncol
, vol.26
, pp. 405-417
-
-
Rew, D.A.1
Wilson, G.D.2
-
74
-
-
34547842118
-
Predicting the active doses in humans from animal studies: A novel approach in oncology
-
Rocchetti M, Simeoni M, Pesenti E, de Nicolao G, Poggesi I (2007) Predicting the active doses in humans from animal studies: a novel approach in oncology. Eur J Cancer 43:1862-1868
-
(2007)
Eur J Cancer
, vol.43
, pp. 1862-1868
-
-
Rocchetti, M.1
Simeoni, M.2
Pesenti, E.3
de Nicolao, G.4
Poggesi, I.5
-
75
-
-
77949321968
-
Progression-free survival as surrogate and as true end point: Insights from the breast and colorectal cancer literature
-
Saad ED, Katz A, Hoff PM, Buyse M (2010) Progression-free survival as surrogate and as true end point: insights from the breast and colorectal cancer literature. Ann Oncol 21:7-12
-
(2010)
Ann Oncol
, vol.21
, pp. 7-12
-
-
Saad, E.D.1
Katz, A.2
Hoff, P.M.3
Buyse, M.4
-
76
-
-
69449097334
-
From trial and error to trial simulation. Part 2: An appraisal of current beliefs in the design and analysis of clinical trials for antidepressant drugs
-
Santen G, Horrigan J, Danhof M, Della Pasqua O (2009) From trial and error to trial simulation. Part 2: an appraisal of current beliefs in the design and analysis of clinical trials for antidepressant drugs. Clin Pharmacol Ther 86(3):255-262
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.3
, pp. 255-262
-
-
Santen, G.1
Horrigan, J.2
Danhof, M.3
Della Pasqua, O.4
-
77
-
-
55949094052
-
Relationship between effects on time-to-disease progression and overall survival in studies of metastatic breast cancer
-
Sherrill B, Amonkar M, Wu Y, Hirst C, Stein S, Walker M, Cuzick J (2008) Relationship between effects on time-to-disease progression and overall survival in studies of metastatic breast cancer. Br J Cancer 99:1572-1578
-
(2008)
Br J Cancer
, vol.99
, pp. 1572-1578
-
-
Sherrill, B.1
Amonkar, M.2
Wu, Y.3
Hirst, C.4
Stein, S.5
Walker, M.6
Cuzick, J.7
-
78
-
-
0346666718
-
Cancer treatment by telomerase inhibitors: Predictions by a kinetic model
-
Sidorov IA, Hirsch KS, Harley CB, Dimitrov DS (2003) Cancer treatment by telomerase inhibitors: predictions by a kinetic model. Math Biosci 181:209-221
-
(2003)
Math Biosci
, vol.181
, pp. 209-221
-
-
Sidorov, I.A.1
Hirsch, K.S.2
Harley, C.B.3
Dimitrov, D.S.4
-
79
-
-
0842282616
-
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents
-
Simeoni M, Magni P, Cammia C, De Nicolao G, Croci V, Pesenti E, Germani M, Poggesi I, Rocchetti M (2004) Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents. Cancer Res 64:1094-1101
-
(2004)
Cancer Res
, vol.64
, pp. 1094-1101
-
-
Simeoni, M.1
Magni, P.2
Cammia, C.3
de Nicolao, G.4
Croci, V.5
Pesenti, E.6
Germani, M.7
Poggesi, I.8
Rocchetti, M.9
-
81
-
-
71049148896
-
Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics
-
Steimer JL, Dahl SG, De Alwis DP, Gundert-Remy U, Karlsson MO, Martinkova J, Aarons L, Ahr HJ, Clairambault J, Freyer G, Friberg LE, Kern SE, Kopp-Schneider A, Ludwig WD, De Nicolao G, Rocchetti M, Troconiz IF (2010) Modelling the genesis and treatment of cancer: the potential role of physiologically based pharmacodynamics. Eur J Cancer 46:21-32
-
(2010)
Eur J Cancer
, vol.46
, pp. 21-32
-
-
Steimer, J.L.1
Dahl, S.G.2
de Alwis, D.P.3
Gundert-Remy, U.4
Karlsson, M.O.5
Martinkova, J.6
Aarons, L.7
Ahr, H.J.8
Clairambault, J.9
Freyer, G.10
Friberg, L.E.11
Kern, S.E.12
Kopp-Schneider, A.13
Ludwig, W.D.14
de Nicolao, G.15
Rocchetti, M.16
Troconiz, I.F.17
-
82
-
-
0242607878
-
Virtual and real brain tumors: Using mathematical modeling to quantify glioma growth and invasion
-
Swanson KR, Bridge C, Murray JD, Alvord EC Jr (2003) Virtual and real brain tumors: using mathematical modeling to quantify glioma growth and invasion. J Neurol Sci 216(1):1-10
-
(2003)
J Neurol Sci
, vol.216
, Issue.1
, pp. 1-10
-
-
Swanson, K.R.1
Bridge, C.2
Murray, J.D.3
Alvord Jr., E.C.4
-
83
-
-
0032406190
-
Stochastic modeling of carcinogenesis: Some new insights
-
Tan WY, Chen CW (1998) Stochastic modeling of carcinogenesis: some new insights. Math Comput Modelling 28(11):49-71
-
(1998)
Math Comput Modelling
, vol.28
, Issue.11
, pp. 49-71
-
-
Tan, W.Y.1
Chen, C.W.2
-
84
-
-
0022635857
-
Experimental chemotherapy and concepts related to the cell cycle
-
Tannock I (1986) Experimental chemotherapy and concepts related to the cell cycle. Int J Radiat Biol 49:335-355
-
(1986)
Int J Radiat Biol
, vol.49
, pp. 335-355
-
-
Tannock, I.1
-
85
-
-
24144455629
-
Pharmacokinetics and concentration-effect relationships of therapeutic monoclonal antibodies and fusion proteins
-
Ternant D, Paintaud G (2005) Pharmacokinetics and concentration-effect relationships of therapeutic monoclonal antibodies and fusion proteins. Expert Opin Biol There 5(Suppl 1):S37-S47
-
(2005)
Expert Opin Biol There
, vol.5
, Issue.SUPPL. 1
-
-
Ternant, D.1
Paintaud, G.2
-
86
-
-
48249084994
-
A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients
-
Tham LS, Wang L, Soo RA, Lee SC, Lee HS, Yong PW, Goh BC, Holford NHG (2008) A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients. Clin Cancer Res 14(13):4213-4218
-
(2008)
Clin Cancer Res
, vol.14
, Issue.13
, pp. 4213-4218
-
-
Tham, L.S.1
Wang, L.2
Soo, R.A.3
Lee, S.C.4
Lee, H.S.5
Yong, P.W.6
Goh, B.C.7
Holford, N.H.G.8
-
87
-
-
0028936012
-
A mathematical model of glioma growth: The effect of chemotherapy on spatio-temporal growth
-
Tracqui P, Cruywagen GC, Woodward DE, Bartoo GT, Murray JD, Alvord EC Jr (1995) A mathematical model of glioma growth: the effect of chemotherapy on spatio-temporal growth. Cell Prolif 28:17-31
-
(1995)
Cell Prolif
, vol.28
, pp. 17-31
-
-
Tracqui, P.1
Cruywagen, G.C.2
Woodward, D.E.3
Bartoo, G.T.4
Murray, J.D.5
Alvord Jr., E.C.6
-
88
-
-
85089317937
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Guidance for industry: Clinical trial endpoints for the approval of cancer drugs and biologics
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (2007) Guidance for industry: Clinical trial endpoints for the approval of cancer drugs and biologics.
-
(2007)
-
-
-
89
-
-
0038826619
-
Pharmacokinetic-pharmacodynamic guided trial design in oncology
-
van Kesteren Ch, Mathôt RA, Beijnen JH, Schellens JH (2003) Pharmacokinetic-pharmacodynamic guided trial design in oncology. Invest New Drugs 21(2):225-241
-
(2003)
Invest New Drugs
, vol.21
, Issue.2
, pp. 225-241
-
-
van Kesteren, C.1
Mathôt, R.A.2
Beijnen, J.H.3
Schellens, J.H.4
-
90
-
-
0034520354
-
Clinical trial simulation of docetaxel in patients with cancer as a tool for dosage optimization
-
Veyrat-Follet C, Bruno R, Olivares R, Rhodes GR, Chaikin P (2000) Clinical trial simulation of docetaxel in patients with cancer as a tool for dosage optimization. Clin Pharmacol Ther 68 (6):677-687
-
(2000)
Clin Pharmacol Ther
, vol.68
, Issue.6
, pp. 677-687
-
-
Veyrat-Follet, C.1
Bruno, R.2
Olivares, R.3
Rhodes, G.R.4
Chaikin, P.5
-
91
-
-
67651171223
-
Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development
-
Wang Y, Sung C, Dartois C, Ramchandani R, Booth BP, Rock E, Gobburu J (2009) Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development. Clin Pharmacol Ther 86(2):167-174
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.2
, pp. 167-174
-
-
Wang, Y.1
Sung, C.2
Dartois, C.3
Ramchandani, R.4
Booth, B.P.5
Rock, E.6
Gobburu, J.7
-
92
-
-
73149095170
-
The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models
-
Williamson MJ, Silva MD, Terkelsen J, Robertson R, Yu L, Xia C, Hatsis P, Bannerman B, Babcock T, Cao Y, Kupperman E (2009) The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models. Mol Cancer Ther 8:3234-3243
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3234-3243
-
-
Williamson, M.J.1
Silva, M.D.2
Terkelsen, J.3
Robertson, R.4
Yu, L.5
Xia, C.6
Hatsis, P.7
Bannerman, B.8
Babcock, T.9
Cao, Y.10
Kupperman, E.11
-
93
-
-
0026345347
-
Assessment of human tumor proliferation using bromodeoxyuridine - current status
-
Wilson GD (1991) Assessment of human tumor proliferation using bromodeoxyuridine - current status. Acta Oncol 30:903-910
-
(1991)
Acta Oncol
, vol.30
, pp. 903-910
-
-
Wilson, G.D.1
-
94
-
-
46449090520
-
Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models
-
Yamazaki S, Skaptason J, Romero D, Lee JH, Zou HY, Christensen JG, Koup JR, Smith BJ, Koudriakova T (2008) Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models. Drug Metab Dispos 36(7):1267-1274
-
(2008)
Drug Metab Dispos
, vol.36
, Issue.7
, pp. 1267-1274
-
-
Yamazaki, S.1
Skaptason, J.2
Romero, D.3
Lee, J.H.4
Zou, H.Y.5
Christensen, J.G.6
Koup, J.R.7
Smith, B.J.8
Koudriakova, T.9
-
95
-
-
46549087597
-
Advantages of prostate-specific antigen (PSA) clearance model over simple PSA half-life computation to describe PSA decrease after prostate adenomectomy
-
You B, Perrin P, Freyer G, Ruffion A, Tranchand B, Hénin E, Paparel P, Ribba B, Devonec M, Falandry C, Fournel C, Tod M, Girard P (2008a) Advantages of prostate-specific antigen (PSA) clearance model over simple PSA half-life computation to describe PSA decrease after prostate adenomectomy. Clin Biochem 41:785-795
-
(2008)
Clin Biochem
, vol.41
, pp. 785-795
-
-
You, B.1
Perrin, P.2
Freyer, G.3
Ruffion, A.4
Tranchand, B.5
Hénin, E.6
Paparel, P.7
Ribba, B.8
Devonec, M.9
Falandry, C.10
Fournel, C.11
Tod, M.12
Girard, P.13
-
96
-
-
55249103429
-
Etoposide pharmacokinetics and survival in patients with small cell lung cancer: A multicentre study
-
You B, Tranchand B, Girard P, Falandry C, Ribba B, Chabaud S, Souquet PJ, Court-Fortune I, Trillet-Lenoir V, Fournel C, Tod M, Freyer G (2008b) Etoposide pharmacokinetics and survival in patients with small cell lung cancer: a multicentre study. Lung Cancer 62(2):261-272
-
(2008)
Lung Cancer
, vol.62
, Issue.2
, pp. 261-272
-
-
You, B.1
Tranchand, B.2
Girard, P.3
Falandry, C.4
Ribba, B.5
Chabaud, S.6
Souquet, P.J.7
Court-Fortune, I.8
Trillet-Lenoir, V.9
Fournel, C.10
Tod, M.11
Freyer, G.12
-
97
-
-
67650917743
-
Prognostic value of modeled PSA clearance on biochemical relapse free survival after radical prostatectomy
-
You B, Girard P, Paparel P, Freyer G, Ruffion A, Charrié A, Hénin E, Tod M, Perrin P (2009) Prognostic value of modeled PSA clearance on biochemical relapse free survival after radical prostatectomy. Prostate 69(12):1325-1333
-
(2009)
Prostate
, vol.69
, Issue.12
, pp. 1325-1333
-
-
You, B.1
Girard, P.2
Paparel, P.3
Freyer, G.4
Ruffion, A.5
Charrié, A.6
Hénin, E.7
Tod, M.8
Perrin, P.9
-
98
-
-
77955232710
-
Predictive values of hCG clearance for risk of methotrexate resistance in low-risk gestational trophoblastic neoplasias
-
doi:10.1093/annonc/mdq033
-
You B, Pollet-Villard M, Fronton L, Labrousse C, Schott AM, Hajri T, Girard P, Freyer G, Tod M, Tranchand B, Colomban O, Ribba B, Raudrant D, Massardier J, Chabaud S, Golfier F (2010) Predictive values of hCG clearance for risk of methotrexate resistance in low-risk gestational trophoblastic neoplasias. Ann Oncol. doi:10.1093/annonc/mdq033
-
(2010)
Ann Oncol
-
-
You, B.1
Pollet-Villard, M.2
Fronton, L.3
Labrousse, C.4
Schott, A.M.5
Hajri, T.6
Girard, P.7
Freyer, G.8
Tod, M.9
Tranchand, B.10
Colomban, O.11
Ribba, B.12
Raudrant, D.13
Massardier, J.14
Chabaud, S.15
Golfier, F.16
-
99
-
-
51649109206
-
Population pharmacokinetic and pharmacodynamic analysis to support treatment optimization of combination chemotherapy with indisulam and carboplatin
-
Zandvliet AS, Schellens JHM, Dittrich C, Wanders J, Beijnen JH, Huitema ADR (2008) Population pharmacokinetic and pharmacodynamic analysis to support treatment optimization of combination chemotherapy with indisulam and carboplatin. Br J Clin Pharmacol 66(4):485-497
-
(2008)
Br J Clin Pharmacol
, vol.66
, Issue.4
, pp. 485-497
-
-
Zandvliet, A.S.1
Schellens, J.H.M.2
Dittrich, C.3
Wanders, J.4
Beijnen, J.H.5
Huitema, A.D.R.6
|