메뉴 건너뛰기




Volumn 19, Issue 10, 2002, Pages 1537-1543

Receptor-mediated pharmacokinetic/pharmacodynamic model of interferon-β 1a in humans

Author keywords

Humans; Interferon beta; Mathematical modeling; Pharmacodynamics; Pharmacokinetics

Indexed keywords

BETA1A INTERFERON; NEOPTERIN; NEUTRALIZING ANTIBODY; RECEPTOR;

EID: 0036803408     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020468902694     Document Type: Article
Times cited : (54)

References (25)
  • 2
    • 0002028093 scopus 로고    scopus 로고
    • Type I cytokines and interferons and their receptors
    • W. Paul (ed.), Lippincott-Raven, Philadelphia, Pennsylvania
    • W. Leonard. Type I cytokines and interferons and their receptors. In W. Paul (ed.), Fundamental Immunology, Lippincott-Raven, Philadelphia, Pennsylvania, 1999 pp. 741-774.
    • (1999) Fundamental Immunology , pp. 741-774
    • Leonard, W.1
  • 4
    • 0030949180 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of two recombinant human interferon beta-1a (IFN beta-1 a) products administered intramuscularly in healthy male and female volunteers
    • J. Alam, S. Goelz, P. Rioux, J. Scaramucci, W. Jones, A. McAllister, M. Campion, and M. Rogge. Comparative pharmacokinetics and pharmacodynamics of two recombinant human interferon beta-1a (IFN beta-1 a) products administered intramuscularly in healthy male and female volunteers. Pharm. Res. 14:546-549 (1997).
    • (1997) Pharm. Res. , vol.14 , pp. 546-549
    • Alam, J.1    Goelz, S.2    Rioux, P.3    Scaramucci, J.4    Jones, W.5    McAllister, A.6    Campion, M.7    Rogge, M.8
  • 5
    • 0027414663 scopus 로고
    • Pharmacokinetics of recombinant human interferon-beta ser in healthy volunteers and its effect on serum neopterin
    • J. Chiang, C. A. Gloff, C. N. Yoshizawa, and G. J. Williams. Pharmacokinetics of recombinant human interferon-beta ser in healthy volunteers and its effect on serum neopterin. Pharm. Res. 10:567-572 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 567-572
    • Chiang, J.1    Gloff, C.A.2    Yoshizawa, C.N.3    Williams, G.J.4
  • 8
    • 0029912760 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers
    • P. Salmon, J. Y. Le Cotonnec, A. Galazka, A. Abdul-Ahad, and A. Darragh. Pharmacokinetics and pharmacodynamics of recombinant human interferon- beta in healthy male volunteers. J. Interferon Cytokine Res. 16:759-764 (1996).
    • (1996) J. Interferon Cytokine Res. , vol.16 , pp. 759-764
    • Salmon, P.1    Le Cotonnec, J.Y.2    Galazka, A.3    Abdul-Ahad, A.4    Darragh, A.5
  • 9
    • 0011166036 scopus 로고    scopus 로고
    • Receptor-mediated pharmacokinetics and pharmacodynamics of IFN-beta 1a following intravenous and subcutaneous dosing in monkeys
    • AAPS, Orlando, Florida
    • D. E. Mager, B. Neuteboom, A. Murafo, C. Efthymiopoulos, and W. J. Jusko. Receptor-mediated pharmacokinetics and pharmacodynamics of IFN-beta 1a following intravenous and subcutaneous dosing in monkeys. In Pharmaceutical Congress of the Americas. AAPS, Orlando, Florida, 2001.
    • (2001) Pharmaceutical Congress of the Americas
    • Mager, D.E.1    Neuteboom, B.2    Murafo, A.3    Efthymiopoulos, C.4    Jusko, W.J.5
  • 10
    • 0035730322 scopus 로고    scopus 로고
    • General pharmacokinetic model for drugs exhibiting target-mediated drug disposition
    • D. E. Mager and W. J. Jusko. General pharmacokinetic model for drugs exhibiting target-mediated drug disposition. J. Pharmacokinet. Pharmacodyn. 28:507-532 (2001).
    • (2001) J. Pharmacokinet. Pharmacodyn. , vol.28 , pp. 507-532
    • Mager, D.E.1    Jusko, W.J.2
  • 12
    • 0021253765 scopus 로고
    • Studies of the interferon receptors
    • K. C. Zoon and H. Arnheiter. Studies of the interferon receptors. Pharmacol. Ther. 24:259-278 (1984).
    • (1984) Pharmacol. Ther. , vol.24 , pp. 259-278
    • Zoon, K.C.1    Arnheiter, H.2
  • 14
    • 0025287316 scopus 로고
    • Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration
    • A. Supersaxo, W. Hein, and H. Steffen. Effect of molecular weight on the lymphatic absorption of water-soluble compounds following subcutaneous administration. Pharm. Res. 7:167-169 (1990).
    • (1990) Pharm. Res. , vol.7 , pp. 167-169
    • Supersaxo, A.1    Hein, W.2    Steffen, H.3
  • 15
    • 0027066967 scopus 로고
    • The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases
    • D. Fuchs, G. Weiss, G. Reibnegger, and H. Wachter. The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases. Crit. Rev. Clin. Lab. Sci. 29:307-341 (1992).
    • (1992) Crit. Rev. Clin. Lab. Sci. , vol.29 , pp. 307-341
    • Fuchs, D.1    Weiss, G.2    Reibnegger, G.3    Wachter, H.4
  • 16
    • 0031742890 scopus 로고    scopus 로고
    • Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomena
    • A. Sharma, W. F. Ebling, and W. J. Jusko. Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomena. J. Pharm. Sci. 87:1577-1584 (1998).
    • (1998) J. Pharm. Sci. , vol.87 , pp. 1577-1584
    • Sharma, A.1    Ebling, W.F.2    Jusko, W.J.3
  • 17
    • 0003117506 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of protein therapeutics
    • R. E. Reid (ed.), University of British Columbia, Vancouver
    • R. Braeckman. Pharmacokinetics and pharmacodynamics of protein therapeutics. In R. E. Reid (ed.), Peptide and Protein Drug Analysis, University of British Columbia, Vancouver, 1999 pp. 633-669.
    • (1999) Peptide and Protein Drug Analysis , pp. 633-669
    • Braeckman, R.1
  • 18
    • 0027769745 scopus 로고
    • Comparison of four basic models of indirect pharmacodynamic responses
    • N. L. Dayneka, V. Garg, and W. J. Jusko. Comparison of four basic models of indirect pharmacodynamic responses. J. Pharmacokinet. Biopharm. 21:457-478 (1993).
    • (1993) J. Pharmacokinet. Biopharm. , vol.21 , pp. 457-478
    • Dayneka, N.L.1    Garg, V.2    Jusko, W.J.3
  • 19
    • 0023858202 scopus 로고
    • An area function method for estimating the apparent absorption rate constant
    • H. Cheng, A. Staubus, and L. Shum. An area function method for estimating the apparent absorption rate constant. Pharm. Res. 5:57-60 (1988).
    • (1988) Pharm. Res. , vol.5 , pp. 57-60
    • Cheng, H.1    Staubus, A.2    Shum, L.3
  • 21
    • 0035949741 scopus 로고    scopus 로고
    • Serum IFN neutralizing antibodies and neopterin levels in a cross-section of MS patients
    • S. D. Cook, J. R. Quinless, A. Jotkowitz, P. Beaton, and the Neutralizing Antibody Study Group. Serum IFN neutralizing antibodies and neopterin levels in a cross-section of MS patients. Neurology 57:1080-1084 (2001).
    • (2001) Neurology , vol.57 , pp. 1080-1084
    • Cook, S.D.1    Quinless, J.R.2    Jotkowitz, A.3    Beaton, P.4
  • 22
    • 0024634393 scopus 로고
    • Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body
    • Y. Sugiyama and M. Hanano. Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body. Pharm. Res. 6:192-202 (1989).
    • (1989) Pharm. Res. , vol.6 , pp. 192-202
    • Sugiyama, Y.1    Hanano, M.2
  • 23
    • 0027998106 scopus 로고
    • Pharmacologic target-mediated drug disposition
    • G. Levy. Pharmacologic target-mediated drug disposition. Clin. Pharmacol. Ther. 56:248-252 (1994).
    • (1994) Clin. Pharmacol. Ther. , vol.56 , pp. 248-252
    • Levy, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.