Combination of lymphocyte number and function in evaluating host immunity

Aging

Volumn 11, Issue 24, 2019, Pages 12685-12707

  Luo, Ying ^a   Xie, Yalong ^a   Zhang, Weijie ^a   Lin, Qun ^a   Tang, Guoxing ^a   Wu, Shiji ^a   Huang, Min ^a   Yin, Botao ^a   Huang, Jin ^a   Wei, Wei ^a   Yu, Jing ^a   Hou, Hongyan ^a   Mao, Liyan ^a   Liu, Weiyong ^a   Wang, Feng ^a   Sun, Ziyong ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Evaluation; Host immunity; Lymphocyte function; Lymphocyte number

Indexed keywords

CALCIUM IONOPHORE; GAMMA INTERFERON; IONOMYCIN; PHORBOL ESTER; PHORBOL-12,13-DIACETATE;

ADOLESCENT; ADULT; AGED; CELLULAR IMMUNITY; CHILD; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFANT; LYMPHOCYTE; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PRESCHOOL CHILD; RISK; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CALCIUM IONOPHORES; CHILD; CHILD, PRESCHOOL; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, CELLULAR; INFANT; INTERFERON-GAMMA; IONOMYCIN; LYMPHOCYTES; MALE; MIDDLE AGED; PHORBOL ESTERS; RISK; YOUNG ADULT;

EID: 85077475791     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.102595     Document Type: Article

References (53)

1. Albert-Vega C, Tawfik DM, Trouillet-Assant S, Vachot L, Mallet F, Textoris J. Immune Functional Assays, From Custom to Standardized Tests for Precision Medicine. Front Immunol. 2018; 9:2367. https://doi.org/10.3389/fimmu.2018.02367 PMID:30386334
2. Barten MJ, Gummert JF, van Gelder T, Shorthouse R, Morris RE. Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. J Immunol Methods. 2001; 253:95-112. https://doi.org/10.1016/S0022-1759(01)00369-6 PMID:11384672
3. Burleson GR, Burleson FG, Dietert RR. The cytotoxic T lymphocyte assay for evaluating cell-mediated immune function. Methods Mol Biol. 2010; 598:195-205. https://doi.org/10.1007/978-1-60761-401-2_14 PMID:19967515
4. Burleson GR, Burleson FG, Dietert RR. Evaluation of Cell-Mediated Immune Function Using the Cytotoxic T-Lymphocyte Assay. Methods Mol Biol. 2018; 1803:199-208. https://doi.org/10.1007/978-1-4939-8549-4_13 PMID:29882141
5. Fauce SR, Yang OO, Effros RB. Autologous CD4/CD8 co-culture assay: a physiologically-relevant composite measure of CD8+ T lymphocyte function in HIV-infected persons. J Immunol Methods. 2007; 327:75-81. https://doi.org/10.1016/j.jim.2007.07.017 PMID:17716683
6. Fleisher TA, Oliveira JB. Functional and molecular evaluation of lymphocytes. J Allergy Clin Immunol. 2004; 114:227-34. https://doi.org/10.1016/j.jaci.2004.06.001 PMID:15316494
7. Locke BA, Dasu T, Verbsky JW. Laboratory diagnosis of primary immunodeficiencies. Clin Rev Allergy Immunol. 2014; 46:154-68. https://doi.org/10.1007/s12016-014-8412-4 PMID:24569953
8. Reddy M, Eirikis E, Davis C, Davis HM, Prabhakar U. Comparative analysis of lymphocyte activation marker expression and cytokine secretion profile in stimulated human peripheral blood mononuclear cell cultures: an in vitro model to monitor cellular immune function. J Immunol Methods. 2004; 293:127-42. https://doi.org/10.1016/j.jim.2004.07.006 PMID:15541283
9. Rubin TS, Zhang K, Gifford C, Lane A, Choo S, Bleesing JJ, Marsh RA. Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH. Blood. 2017; 129:2993-99. https://doi.org/10.1182/blood-2016-12-753830 PMID:28270454
10. Chraa D, Naim A, Olive D, Badou A. T lymphocyte subsets in cancer immunity: Friends or foes. J Leukoc Biol. 2019; 105:243-255. https://doi.org/10.1002/JLB.MR0318-097R PMID:30387907
11. Folds JD, Schmitz JL. 24. Clinical and laboratory assessment of immunity. J Allergy Clin Immunol. 2003 (2 Suppl); 111:S702-11. https://doi.org/10.1067/mai.2003.122 PMID:12592315
12. Nagata T, Kiriike N, Tobitani W, Kawarada Y, Matsunaga H, Yamagami S. Lymphocyte subset, lymphocyte proliferative response, and soluble interleukin-2 receptor in anorexic patients. Biol Psychiatry. 1999; 45:471-74. https://doi.org/10.1016/S0006-3223(98)00082-1 PMID:10071720
13. Richards SJ, Norfolk DR, Swirsky DM, Hillmen P. Lymphocyte subset analysis and glycosylphosphatidylinositol phenotype in patients with paroxysmal nocturnal hemoglobinuria. Blood. 1998; 92:1799-806. https://doi.org/10.1182/blood.V92.5.1799 PMID:9716611
14. Semnani RT, Nutman TB, Hochman P, Shaw S, van Seventer GA. Costimulation by purified intercellular adhesion molecule 1 and lymphocyte function-associated antigen 3 induces distinct proliferation, cytokine and cell surface antigen profiles in human "naive" and "memory" CD4+ T cells. J Exp Med. 1994; 180:2125-35. https://doi.org/10.1084/jem.180.6.2125 PMID:7525848
15. Speciale L, Calabrese E, Saresella M, Tinelli C, Mariani C, Sanvito L, Longhi R, Ferrante P. Lymphocyte subset patterns and cytokine production in Alzheimer's disease patients. Neurobiol Aging. 2007; 28:1163-69. https://doi.org/10.1016/j.neurobiolaging.2006.05.020 PMID:16814429
16. Hou H, Zhou Y, Yu J, Mao L, Bosco MJ, Wang J, Lu Y, Mao L, Wu X, Wang F, Sun Z. Establishment of the Reference Intervals of Lymphocyte Function in Healthy Adults Based on IFN-γ Secretion Assay upon Phorbol-12-Myristate-13-Acetate/Ionomycin Stimulation. Front Immunol. 2018; 9:172. https://doi.org/10.3389/fimmu.2018.00172 PMID:29467761
17. Lindemann M. Ex vivo assessment of cellular immune function -applications in patient care and clinical studies. Tissue Antigens. 2014; 84:439-49. https://doi.org/10.1111/tan.12454 PMID:25329632
18. Marits P, Wikström AC, Popadic D, Winqvist O, Thunberg S. Evaluation of T and B lymphocyte function in clinical practice using a flow cytometry based proliferation assay. Clin Immunol. 2014; 153:332-42. https://doi.org/10.1016/j.clim.2014.05.010 PMID:24909732
19. Bol SJ, Rosdorff HJ, Ronteltap CP, Hennen LA. Cellular cytotoxicity assessed by the 51Cr release assay. Biological interpretation of mathematical parameters. J Immunol Methods. 1986; 90:15-23. https://doi.org/10.1016/0022-1759(86)90378-9 PMID:3486921
20. Hu VW, Black GE, Torres-Duarte A, Abramson FP. 3H-thymidine is a defective tool with which to measure rates of DNA synthesis. FASEB J. 2002; 16:1456-57. https://doi.org/10.1096/fj.02-0142fje PMID:12205046
21. Laštovicka J, Rataj M, Bartunková J. Assessment of lymphocyte proliferation for diagnostic purpose: comparison of CFSE staining, Ki-67 expression and 3H-thymidine incorporation. Hum Immunol. 2016; 77:1215-22. https://doi.org/10.1016/j.humimm.2016.08.012 PMID:27562802
22. Quah BJ, Warren HS, Parish CR. Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl ester. Nat Protoc. 2007; 2:2049-56. https://doi.org/10.1038/nprot.2007.296 PMID:17853860
23. Stulting RD, Berke G. The use of 51Cr release as a measure of lymphocyte-mediated cytolysis in vitro. Cell Immunol. 1973; 9:474-76. https://doi.org/10.1016/0008-8749(73)90062-2 PMID:4758877
24. Choi J, Lee SJ, Lee YA, Maeng HG, Lee JK, Kang YW. Reference values for peripheral blood lymphocyte subsets in a healthy korean population. Immune Netw. 2014; 14:289-95. https://doi.org/10.4110/in.2014.14.6.289 PMID:25550695
25. Qin L, Jing X, Qiu Z, Cao W, Jiao Y, Routy JP, Li T. Aging of immune system: immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults. Aging (Albany NY). 2016; 8:848-59. https://doi.org/10.18632/aging.100894 PMID:26886066
26. Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara DW, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, et al, and Pediatric AIDS Clinical Trials Group. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol. 2003; 112:973-80. https://doi.org/10.1016/j.jaci.2003.07.003 PMID:14610491
27. Zhang K, Wang F, Zhang M, Cao X, Yang S, Jia S, Wang L, Luo J, Deng S, Chen M. Reference ranges of lymphocyte subsets balanced for age and gender from a population of healthy adults in Chongqing District of China. Cytometry B Clin Cytom. 2016; 90:538-42. https://doi.org/10.1002/cyto.b.21323 PMID:26352589
28. Gardner EM, Murasko DM. Age-related changes in Type 1 and Type 2 cytokine production in humans. Biogerontology. 2002; 3:271-90. https://doi.org/10.1023/A:1020151401826 PMID:12237564
29. Rink L, Cakman I, Kirchner H. Altered cytokine production in the elderly. Mech Ageing Dev. 1998; 102:199-209. https://doi.org/10.1016/S0047-6374(97)00153-X PMID:9720652
30. Valiathan R, Ashman M, Asthana D. Effects of Ageing on the Immune System: infants to Elderly. Scand J Immunol. 2016; 83:255-66. https://doi.org/10.1111/sji.12413 PMID:26808160
31. Jia L, Li J, Zhang Y, Shi Y, Yuan E, Liu J, Wang P, Rong S, Xing J, Tian Y, Li J. Age-and sex-related reference intervals of lymphocyte subsets in healthy ethnic Han Chinese children. Cytometry A. 2015; 87:1116-26. https://doi.org/10.1002/cyto.a.22716 PMID:26155000
32. Jiao Y, Qiu Z, Xie J, Li D, Li T. Reference ranges and age-related changes of peripheral blood lymphocyte subsets in Chinese healthy adults. Sci China C Life Sci. 2009; 52:643-50. https://doi.org/10.1007/s11427-009-0086-4 PMID:19641869
33. Batool R, Butt MS, Sultan MT, Saeed F, Naz R. Protein-energy malnutrition: a risk factor for various ailments. Crit Rev Food Sci Nutr. 2015; 55:242-53. https://doi.org/10.1080/10408398.2011.651543 PMID:24915388
34. Katz M. Malnutrition and immunity. J Infect Dis. 1992; 166:1458. https://doi.org/10.1093/infdis/166.6.1458-a PMID:1431266
35. Schaible UE, Kaufmann SH. Malnutrition and infection: complex mechanisms and global impacts. PLoS Med. 2007; 4:e115. https://doi.org/10.1371/journal.pmed.0040115 PMID:17472433
36. Cardemil CV, Jonas A, Gerber S, Weldon WC 3rd, Oberste MS, Beukes A, Sawadogo S, Patel SV, Zeko S, Muroua C, Gaeb E, Wannemuehler K, Goodson JL. Poliovirus immunity among pregnant females aged 15-44 years, Namibia, 2010. J Infect Dis. 2014 (Suppl 1); 210:S136-42. https://doi.org/10.1093/infdis/jiu086 PMID:25316828
37. Liu P, Xu L, Sun Y, Wang Z. The prevalence and risk of human papillomavirus infection in pregnant women. Epidemiol Infect. 2014; 142:1567-78. https://doi.org/10.1017/S0950268814000636 PMID:24667102
38. Morales-Suárez-Varela M, Kaerlev L, Zhu JL, Llopis-González A, Gimeno-Clemente N, Nohr EA, Bonde JP, Olsen J. Risk of infection and adverse outcomes among pregnant working women in selected occupational groups: A study in the Danish National Birth Cohort. Environ Health. 2010; 9:70. https://doi.org/10.1186/1476-069X-9-70 PMID:21078155
39. Berrou J, Fougeray S, Venot M, Chardiny V, Gautier JF, Dulphy N, Toubert A, Peraldi MN. Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes. PLoS One. 2013; 8:e62418. https://doi.org/10.1371/journal.pone.0062418 PMID:23638076
40. Sakowicz-Burkiewicz M, Pawelczyk T. Recent advances in understanding the relationship between adenosine metabolism and the function of T and B lymphocytes in diabetes. J Physiol Pharmacol. 2011; 62:505-12. PMID:22204797
41. Wang H, Wang C, Wang L, Liu T, Wang Z, You H, Zheng Y, Luo D. Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus. Biochem Biophys Res Commun. 2018; 500:384-90. https://doi.org/10.1016/j.bbrc.2018.04.083 PMID:29654766
42. Wesselius LJ, Wheaton DL, Manahan-Wahl LJ, Sherard SL, Taylor SA, Abdou NA. Lymphocyte subsets in lung cancer. Chest. 1987; 91:725-29. https://doi.org/10.1378/chest.91.5.725 PMID:3032522
43. Xiang FF, Zhu JM, Cao XS, Shen B, Zou JZ, Liu ZH, Zhang H, Teng J, Liu H, Ding XQ. Lymphocyte depletion and subset alteration correlate to renal function in chronic kidney disease patients. Ren Fail. 2016; 38:7-14. https://doi.org/10.3109/0886022X.2015.1106871 PMID:26539739
44. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, et al. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2010; 69:1580-88. https://doi.org/10.1136/ard.2010.138461 PMID:20699241
45. Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010; 62:2569-81. https://doi.org/10.1002/art.27584 PMID:20872595
46. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger TA, Mitchell DM, Neustadt DH, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988; 31:315-24. https://doi.org/10.1002/art.1780310302 PMID:3358796
47. Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, et al, and International Autoimmune Hepatitis Group. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology. 2008; 48:169-76. https://doi.org/10.1002/hep.22322 PMID:18537184
48. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997; 40:1725. https://doi.org/10.1002/art.1780400928 PMID:9324032
49. Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol Suppl. 1989; 170:2-6. https://doi.org/10.3109/00365528909091339 PMID:2617184
50. Sharp CC. Diagnostic criteria for classification of MCTD. In: Kasukawa R, Sharp GC, editors. Mixed connective tissue diseases and anti-nuclear antibodies. Amsterdam: Elsevier; 1987. pp. 23-32.
51. Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X, and International Sjögren's Syndrome Criteria Working Group. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjögren's syndrome: A consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis. 2017; 76:9-16. https://doi.org/10.1136/annrheumdis-2016-210571 PMID:27789466
52. Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, Mariette X, and International Sjögren's Syndrome Criteria Working Group. 2016 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Primary Sjögren's Syndrome: A Consensus and Data-Driven Methodology Involving Three International Patient Cohorts. Arthritis Rheumatol. 2017; 69:35-45. https://doi.org/10.1002/art.39859 PMID:27785888
53. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982; 25:1271-77. https://doi.org/10.1002/art.1780251101 PMID:7138600