메뉴 건너뛰기




Volumn 24, Issue 22, 2019, Pages

A newly discovered phenylethanoid glycoside from Stevia rebaudiana bertoni affects insulin secretion in rat INS-1 islet β cells

Author keywords

DS; Insulin secretion; Phenylethanoid glycoside; Stevia rebaudiana Bertoni; Structure

Indexed keywords

GLYCOSIDE; PLANT EXTRACT;

EID: 85075418886     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules24224178     Document Type: Article
Times cited : (22)

References (40)
  • 2
    • 34247595371 scopus 로고    scopus 로고
    • Characterisation of Stevia rebaudiana by comprehensive two-dimensional liquid chromatography time-of-flight mass spectrometry
    • Pol, J.; Hohnova, B.; Hyotylainen, T. Characterisation of Stevia rebaudiana by comprehensive two-dimensional liquid chromatography time-of-flight mass spectrometry. J. Chromatogr. A 2007, 1150, 85-92. [CrossRef] [PubMed]
    • (2007) J. Chromatogr. A , vol.1150 , pp. 85-92
    • Pol, J.1    Hohnova, B.2    Hyotylainen, T.3
  • 3
    • 0033422220 scopus 로고    scopus 로고
    • Stevioside content of Stevia rebaudiana (Bertoni) Bertoni grown in East Paraguay
    • Tateo, F.; Escobar Sanchez, M.L.; Bononi, M.; Lubian, E. Stevioside content of Stevia rebaudiana (Bertoni) Bertoni grown in East Paraguay. Ital. J. Food Sci. 1999, 11, 265-269.
    • (1999) Ital. J. Food Sci. , vol.11 , pp. 265-269
    • Tateo, F.1    Escobar Sanchez, M.L.2    Bononi, M.3    Lubian, E.4
  • 4
    • 84875231954 scopus 로고    scopus 로고
    • Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana
    • Shivanna, N.; Naika, M.; Khanum, F.; Kaul, V.K. Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana. J. Diabetes Complicat. 2013, 27, 103-113. [CrossRef] [PubMed]
    • (2013) J. Diabetes Complicat. , vol.27 , pp. 103-113
    • Shivanna, N.1    Naika, M.2    Khanum, F.3    Kaul, V.K.4
  • 5
    • 0033818478 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension
    • Chan, P.; Tomlinson, B.; Chen, Y.J.; Liu, J.C.; Hsieh, M.H.; Cheng, J.T. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Brit. J. Clin. Pharmacol. 2000, 50, 215-220. [CrossRef] [PubMed]
    • (2000) Brit. J. Clin. Pharmacol. , vol.50 , pp. 215-220
    • Chan, P.1    Tomlinson, B.2    Chen, Y.J.3    Liu, J.C.4    Hsieh, M.H.5    Cheng, J.T.6
  • 6
    • 77956975964 scopus 로고    scopus 로고
    • Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats
    • Kujur, R.S.; Singh, V.; Ram, M.; Yadava, H.N.; Singh, K.K.; Kumari, S.; Roy, B.K. Antidiabetic activity and phytochemical screening of crude extract of Stevia rebaudiana in alloxan-induced diabetic rats. Pharm. Res. 2010, 2, 258-263.
    • (2010) Pharm. Res. , vol.2 , pp. 258-263
    • Kujur, R.S.1    Singh, V.2    Ram, M.3    Yadava, H.N.4    Singh, K.K.5    Kumari, S.6    Roy, B.K.7
  • 7
  • 9
    • 0020365090 scopus 로고
    • Potential sweetening agents of plant origin. III. Organoleptic evaluation of Stevia leaf herbarium samples for sweetness
    • Soejarto, D.D.; Kinghorn, A.D.; Farnsworth, N.R. Potential sweetening agents of plant origin. III. Organoleptic evaluation of Stevia leaf herbarium samples for sweetness. J. Nat. Prod. 1982, 45, 590. [CrossRef]
    • (1982) J. Nat. Prod. , vol.45 , pp. 590
    • Soejarto, D.D.1    Kinghorn, A.D.2    Farnsworth, N.R.3
  • 12
    • 70449094939 scopus 로고    scopus 로고
    • A new acylated quercetin glycoside from the leaves of Stevia rebaudiana Bertoni
    • Li, J.; Hua, J.; Shi, R. A new acylated quercetin glycoside from the leaves of Stevia rebaudiana Bertoni. Nat. Prod. Res. 2009, 23, 1378-1383. [CrossRef]
    • (2009) Nat. Prod. Res. , vol.23 , pp. 1378-1383
    • Li, J.1    Hua, J.2    Shi, R.3
  • 13
    • 34247150644 scopus 로고    scopus 로고
    • Iridoid glycosides from the stems of Pithecoctenium crucigerum (Bignoniaceae)
    • Martin, F.; Hay, A.E.; Corno, L.; Gupta, M.P.; Hostettmann, K. Iridoid glycosides from the stems of Pithecoctenium crucigerum (Bignoniaceae). Phytochemistry 2007, 68, 1307-1311. [CrossRef] [PubMed]
    • (2007) Phytochemistry , vol.68 , pp. 1307-1311
    • Martin, F.1    Hay, A.E.2    Corno, L.3    Gupta, M.P.4    Hostettmann, K.5
  • 14
    • 79954415300 scopus 로고    scopus 로고
    • Antioxidant and cholinesterases inhibitory activities of Verbascum xanthophoeniceum Griseb. And its phenylethanoid glycosides
    • Georgiev, M.; Alipieva, K.; Orhan, I.; Abrashev, R.; Denev, P.; Angelova, M. Antioxidant and cholinesterases inhibitory activities of Verbascum xanthophoeniceum Griseb. and its phenylethanoid glycosides. Food Chem. 2011, 128, 100-105. [CrossRef] [PubMed]
    • (2011) Food Chem. , vol.128 , pp. 100-105
    • Georgiev, M.1    Alipieva, K.2    Orhan, I.3    Abrashev, R.4    Denev, P.5    Angelova, M.6
  • 15
    • 84858239942 scopus 로고    scopus 로고
    • Cytotoxic and antioxidative activities of Plantago lagopus L. And characterization of its bioactive compounds
    • Harput, U.S.; Genc, Y.; Saracoglu, I. Cytotoxic and antioxidative activities of Plantago lagopus L. and characterization of its bioactive compounds. Food Chem. Toxicol. 2012, 50, 1554-1559. [CrossRef] [PubMed]
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 1554-1559
    • Harput, U.S.1    Genc, Y.2    Saracoglu, I.3
  • 16
    • 78951486316 scopus 로고    scopus 로고
    • Inhibition of aldose reductase by phenylethanoid glycoside isolated from the seeds of Paulownia coreana
    • Kim, J.K.; Lee, Y.S.; Kim, S.H.; Bae, Y.S.; Lim, S.S. Inhibition of aldose reductase by phenylethanoid glycoside isolated from the seeds of Paulownia coreana. Biol. Pharm. Bull. 2011, 34, 160-163. [CrossRef] [PubMed]
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 160-163
    • Kim, J.K.1    Lee, Y.S.2    Kim, S.H.3    Bae, Y.S.4    Lim, S.S.5
  • 17
    • 84931570277 scopus 로고    scopus 로고
    • Hydrolysis enhances bioavailability of proanthocyanidin-derived metabolites and improves beta-cell function in glucose intolerant rats
    • Yang, K.; Hashemi, Z.; Han, W.; Jin, A.; Yang, H.; Ozga, J.; Li, L.; Chan, C.B. Hydrolysis enhances bioavailability of proanthocyanidin-derived metabolites and improves beta-cell function in glucose intolerant rats. J. Nutr. Biochem. 2015, 26, 850-859. [CrossRef]
    • (2015) J. Nutr. Biochem. , vol.26 , pp. 850-859
    • Yang, K.1    Hashemi, Z.2    Han, W.3    Jin, A.4    Yang, H.5    Ozga, J.6    Li, L.7    Chan, C.B.8
  • 18
    • 85046643848 scopus 로고    scopus 로고
    • Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on its antioxidant activity
    • Yang, K.; Chan, C.B. Epicatechin potentiation of glucose-stimulated insulin secretion in INS-1 cells is not dependent on its antioxidant activity. Acta Pharmacol. Sin. 2018, 39, 893-902. [CrossRef]
    • (2018) Acta Pharmacol. Sin. , vol.39 , pp. 893-902
    • Yang, K.1    Chan, C.B.2
  • 21
    • 85065762017 scopus 로고    scopus 로고
    • Quercetin-3-oleoyl derivatives as new GPR40 agonists: Molecular docking studies and functional evaluation
    • Carullo, G.; Perri, M.; Manetti, F.; Aiello, F.; Caroleo, M.C.; Cione, E. Quercetin-3-oleoyl derivatives as new GPR40 agonists: Molecular docking studies and functional evaluation. Bioorg. Med. Chem. Lett. 2019, 29, 1761-1764. [CrossRef]
    • (2019) Bioorg. Med. Chem. Lett. , vol.29 , pp. 1761-1764
    • Carullo, G.1    Perri, M.2    Manetti, F.3    Aiello, F.4    Caroleo, M.C.5    Cione, E.6
  • 22
    • 0030948732 scopus 로고    scopus 로고
    • Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression
    • Clark, S.A.; Quaade, C.; Constandy, H.; Hansen, P.; Halban, P.; Ferber, S.; Newgard, C.B.; Normington, K. Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression. Diabetes 1997, 46, 958. [CrossRef]
    • (1997) Diabetes , vol.46 , pp. 958
    • Clark, S.A.1    Quaade, C.2    Constandy, H.3    Hansen, P.4    Halban, P.5    Ferber, S.6    Newgard, C.B.7    Normington, K.8
  • 24
    • 0035747896 scopus 로고    scopus 로고
    • Substrate specificity of β-primeverosidase, A key enzyme in aroma formation during oolong tea and black tea manufacturing
    • Ma, S.J.; Mizutani, M.; Hiratake, J.; Sakata, K. Substrate specificity of β-primeverosidase, A key enzyme in aroma formation during oolong tea and black tea manufacturing. Biosci. Biotech. Bioch. 2001, 65, 2719-2729. [CrossRef] [PubMed]
    • (2001) Biosci. Biotech. Bioch. , vol.65 , pp. 2719-2729
    • Ma, S.J.1    Mizutani, M.2    Hiratake, J.3    Sakata, K.4
  • 25
    • 0012789594 scopus 로고
    • Phenolic glycosides from the fruit of strychnos nux-vomica
    • Bisset, N.G.; Choudhury, A.K.; Houghton, P.J. Phenolic glycosides from the fruit of strychnos nux-vomica. Phytochemistry 1989, 28, 1553-1554. [CrossRef]
    • (1989) Phytochemistry , vol.28 , pp. 1553-1554
    • Bisset, N.G.1    Choudhury, A.K.2    Houghton, P.J.3
  • 26
    • 77953622153 scopus 로고    scopus 로고
    • Biosynthesis of acteoside in cultured cells of olea europaea
    • Saimaru, H.; Orihara, Y. Biosynthesis of acteoside in cultured cells of olea europaea. J. Nat. Med. 2010, 64, 139-145. [CrossRef]
    • (2010) J. Nat. Med. , vol.64 , pp. 139-145
    • Saimaru, H.1    Orihara, Y.2
  • 27
    • 0033924913 scopus 로고    scopus 로고
    • Identification of lignans as major components in the phenolic fraction of olive oil
    • Owen, R.W.; Mier, W.; Giacosa, A.; Hull, W.E.; Spiegelhalder, B.; Bartsch, H. Identification of lignans as major components in the phenolic fraction of olive oil. Clin. Chem. 2000, 46, 976.
    • (2000) Clin. Chem. , vol.46 , pp. 976
    • Owen, R.W.1    Mier, W.2    Giacosa, A.3    Hull, W.E.4    Spiegelhalder, B.5    Bartsch, H.6
  • 28
    • 84865726859 scopus 로고    scopus 로고
    • NMR-based metabolic profiling and in vitro antioxidant and hepatotoxic assessment of partially purified fractions from Golden germander (Teucrium polium L.) methanolic extract
    • Severina, P.; Brigida, D.A.; Monica, S.; Grazia, D.A.; Marialuisa, G.; Silvia, G.; Pietro, M.; Antonio, F. NMR-based metabolic profiling and in vitro antioxidant and hepatotoxic assessment of partially purified fractions from Golden germander (Teucrium polium L.) methanolic extract. J. Food Chem. 2012, 135, 1957-1967.
    • (2012) J. Food Chem. , vol.135 , pp. 1957-1967
    • Severina, P.1    Brigida, D.A.2    Monica, S.3    Grazia, D.A.4    Marialuisa, G.5    Silvia, G.6    Pietro, M.7    Antonio, F.8
  • 29
    • 78649706279 scopus 로고    scopus 로고
    • The effect of plasma protein binding on in vivo efficacy: Misconceptions in drug discovery
    • Smith, D.A.; Di, L.; Kerns, E.H. The effect of plasma protein binding on in vivo efficacy: Misconceptions in drug discovery. Nat. Rev. Drug Discov. 2010, 9, 929-939. [CrossRef]
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 929-939
    • Smith, D.A.1    Di, L.2    Kerns, E.H.3
  • 30
    • 84904978187 scopus 로고    scopus 로고
    • The log P parameter as a molecular descriptor in the computer-aided drug design-An overview
    • Kujawski, J.; Popielarska, H.; Myka, A.; Drabińska, B.; Bernard, M.K. The log P parameter as a molecular descriptor in the computer-aided drug design-An overview. CMST 2012, 18, 81-88. [CrossRef]
    • (2012) CMST , vol.18 , pp. 81-88
    • Kujawski, J.1    Popielarska, H.2    Myka, A.3    Drabińska, B.4    Bernard, M.K.5
  • 32
    • 84889087917 scopus 로고    scopus 로고
    • Anti-hyperglycemic and hypolipidemic effects of Cistanche tubulosa in type 2 diabetic db/db mice
    • Xiong, W.T.; Gu, L.; Wang, C.; Sun, H.X.; Liu, X. Anti-hyperglycemic and hypolipidemic effects of Cistanche tubulosa in type 2 diabetic db/db mice. J. Ethnopharmacol. 2013, 150, 935-945. [CrossRef]
    • (2013) J. Ethnopharmacol. , vol.150 , pp. 935-945
    • Xiong, W.T.1    Gu, L.2    Wang, C.3    Sun, H.X.4    Liu, X.5
  • 34
    • 0036190439 scopus 로고    scopus 로고
    • Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: Studies in the diabetic Goto-Kakizaki (GK) rats
    • Jeppesen, P.B.; Gregersen, S.; Alstrup, K.K.; Hermansen, K. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: Studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine 2002, 9, 9-14. [CrossRef] [PubMed]
    • (2002) Phytomedicine , vol.9 , pp. 9-14
    • Jeppesen, P.B.1    Gregersen, S.2    Alstrup, K.K.3    Hermansen, K.4
  • 35
    • 77952558121 scopus 로고    scopus 로고
    • Quercitrin, a bioflavonoid improves glucose homeostasis in streptozotocin-induced diabetic tissues by altering glycolytic and gluconeogenic enzymes
    • Babujanarthanam, R.; Kavitha, P.; Pandian, M.R. Quercitrin, a bioflavonoid improves glucose homeostasis in streptozotocin-induced diabetic tissues by altering glycolytic and gluconeogenic enzymes. Fund Clin. Pharmacol. 2010, 24, 357-364. [CrossRef] [PubMed]
    • (2010) Fund Clin. Pharmacol. , vol.24 , pp. 357-364
    • Babujanarthanam, R.1    Kavitha, P.2    Pandian, M.R.3
  • 37
    • 84969766543 scopus 로고    scopus 로고
    • Evaluation of TOPKAT, toxtree, and derek nexus in silico models for ocular irritation and development of a knowledge-based framework to improve the prediction of severe irritation
    • Bhhatarai, B.; Wilson, D.M.; Parks, A.K.; Carney, E.W.; Spencer, P.J. Evaluation of TOPKAT, toxtree, and derek nexus in silico models for ocular irritation and development of a knowledge-based framework to improve the prediction of severe irritation. Chem. Res. Toxicol. 2016, 29, 810-822. [CrossRef] [PubMed]
    • (2016) Chem. Res. Toxicol. , vol.29 , pp. 810-822
    • Bhhatarai, B.1    Wilson, D.M.2    Parks, A.K.3    Carney, E.W.4    Spencer, P.J.5
  • 38
    • 84955278542 scopus 로고    scopus 로고
    • Investigation on the isoform selectivity of novel kinesin-like protein 1 (KIF11) inhibitor using chemical feature based pharmacophore, molecular docking, and quantum mechanical studies
    • Karunagaran, S.; Subhashchandrabose, S.; Lee, K.W.; Meganathan, C. Investigation on the isoform selectivity of novel kinesin-like protein 1 (KIF11) inhibitor using chemical feature based pharmacophore, molecular docking, and quantum mechanical studies. Comput. Biol. Chem. 2016, 61, 47-61. [CrossRef] [PubMed]
    • (2016) Comput. Biol. Chem. , vol.61 , pp. 47-61
    • Karunagaran, S.1    Subhashchandrabose, S.2    Lee, K.W.3    Meganathan, C.4
  • 39
    • 84960338532 scopus 로고    scopus 로고
    • Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking
    • Thiyagarajan, V.; Lin, S.H.; Chang, Y.C.; Weng, C.F. Identification of novel FAK and S6K1 dual inhibitors from natural compounds via ADMET screening and molecular docking. Biomed. Pharm. 2016, 80, 52-62. [CrossRef]
    • (2016) Biomed. Pharm. , vol.80 , pp. 52-62
    • Thiyagarajan, V.1    Lin, S.H.2    Chang, Y.C.3    Weng, C.F.4
  • 40


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.