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Volumn 381, Issue 7, 2019, Pages 668-676

The "all of us" research program

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOMEDICAL TECHNOLOGY ASSESSMENT; BODY MASS; CLINICAL PROTOCOL; COHORT ANALYSIS; CONTROLLED STUDY; DIGITAL LITERACY; ELECTRONIC HEALTH RECORD; FUNDING; GENETIC COUNSELING; GENOTYPE; HEALTH CARE ACCESS; HEALTH CARE PERSONNEL; HEALTH CARE POLICY; HEALTH CARE SYSTEM; HEALTH PROGRAM; HUMAN; LONGITUDINAL STUDY; MACHINE LEARNING; MEDICAL RESEARCH; NATIONAL HEALTH ORGANIZATION; PERSONALIZED MEDICINE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REPRODUCIBILITY; TAXONOMY; WHOLE GENOME SEQUENCING; BIOBANK; HEALTH SURVEY; INFORMATION PROCESSING; METHODOLOGY; OBSERVATIONAL STUDY; UNITED STATES;

EID: 85070840174     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMsr1809937     Document Type: Article
Times cited : (1048)

References (42)
  • 1
    • 84991669666 scopus 로고    scopus 로고
    • Genomics is failing on diversity
    • Popejoy AB, Fullerton SM. Genomics is failing on diversity. Nature 2016; 538: 161-4.
    • (2016) Nature , vol.538 , pp. 161-164
    • Popejoy, A.B.1    Fullerton, S.M.2
  • 2
    • 84962269370 scopus 로고    scopus 로고
    • The FAIR Guiding Principles for scientific data management and stewardship
    • Wilkinson MD, Dumontier M, Aalbersberg IJ, et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 2016; 3: 160018.
    • (2016) Sci Data , vol.3 , pp. 160018
    • Wilkinson, M.D.1    Dumontier, M.2    Aalbersberg, I.J.3
  • 3
    • 84982187833 scopus 로고    scopus 로고
    • Genetic misdiagnoses and the potential for health disparities
    • Manrai AK, Funke BH, Rehm HL, et al. Genetic misdiagnoses and the potential for health disparities. N Engl J Med 2016; 375: 655-65.
    • (2016) N Engl J Med , vol.375 , pp. 655-665
    • Manrai, A.K.1    Funke, B.H.2    Rehm, H.L.3
  • 4
    • 84893351797 scopus 로고    scopus 로고
    • Policy: NIH plans to enhance reproducibility
    • Collins FS, Tabak LA. Policy: NIH plans to enhance reproducibility. Nature 2014; 505: 612-3.
    • (2014) Nature , vol.505 , pp. 612-613
    • Collins, F.S.1    Tabak, L.A.2
  • 5
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015; 372: 793-5.
    • (2015) N Engl J Med , vol.372 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 6
    • 84937824271 scopus 로고    scopus 로고
    • Agency for Healthcare Research and Quality
    • Agency for Healthcare Research and Quality. 2016 National healthcare quality and disparities report (https://www.ahrq.gov/research/ findings/ nhqrdr/ nhqdr16/ index .html).
    • 2016 National Healthcare Quality and Disparities Report
  • 8
    • 84984822363 scopus 로고    scopus 로고
    • A survey of U.S adults' opinions about conduct of a nationwide Precision Medicine Initiative cohort study of genes and environment
    • Kaufman DJ, Baker R, Milner LC, Devaney S, Hudson KL. A survey of U.S adults' opinions about conduct of a nationwide Precision Medicine Initiative cohort study of genes and environment. PLoS One 2016; 11(8): e0160461.
    • (2016) PLoS One , vol.11 , Issue.8 , pp. e0160461
    • Kaufman, D.J.1    Baker, R.2    Milner, L.C.3    Devaney, S.4    Hudson, K.L.5
  • 9
    • 85070839875 scopus 로고    scopus 로고
    • NEJM Catalyst. February 12
    • Wilkins CH. Precision medicine for everyone. NEJM Catalyst. February 12, 2018 (https://catalyst .nejm .org/ precision-medicine-initiative-everyone/ ).
    • (2018) Precision Medicine for Everyone
    • Wilkins, C.H.1
  • 10
    • 85067215674 scopus 로고    scopus 로고
    • Development of the initial surveys for the All of Us Research Program
    • Cronin RM, Jerome RN, Mapes B, et al. Development of the initial surveys for the All of Us Research Program. Epidemiology 2019; 30: 597-608.
    • (2019) Epidemiology , vol.30 , pp. 597-608
    • Cronin, R.M.1    Jerome, R.N.2    Mapes, B.3
  • 11
    • 85067812736 scopus 로고    scopus 로고
    • National Institutes of Health August 4
    • National Institutes of Health. The All of Us Research Program initial protocol. August 4, 2017 (https://allofus .nih.gov/news-events-and-media/ announcements/ all-us-research-program-initial-protocol).
    • (2017) The All of Us Research Program Initial Protocol
  • 12
    • 84952672589 scopus 로고    scopus 로고
    • Demographics Research Group Charlottesville, VA: Weldon Cooper Center for Public Service, July
    • Demographics Research Group. The racial dot map. Charlottesville, VA: Weldon Cooper Center for Public Service, July 2013 (https://demographics .coopercenter .org/ racial-dot-map/ ).
    • (2013) The Racial Dot Map
  • 13
    • 84977265918 scopus 로고    scopus 로고
    • Characterizing treatment pathways at scale using the OHDSI network
    • Hripcsak G, Ryan PB, Duke JD, et al. Characterizing treatment pathways at scale using the OHDSI network. Proc Natl Acad Sci U S A 2016; 113: 7329-36.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , pp. 7329-7336
    • Hripcsak, G.1    Ryan, P.B.2    Duke, J.D.3
  • 14
    • 84926430250 scopus 로고    scopus 로고
    • UK Biobank: An open access resource for identifying the causes of a wide range of complex diseases of middle and old age
    • Sudlow C, Gallacher J, Allen N, et al. UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med 2015; 12(3): e1001779.
    • (2015) PLoS Med , vol.12 , Issue.3 , pp. e1001779
    • Sudlow, C.1    Gallacher, J.2    Allen, N.3
  • 15
    • 85070802815 scopus 로고    scopus 로고
    • Workbench-All of Us research hub
    • Workbench-All of Us research hub (https://www.researchallofus .org/ data/ workbench/ ).
  • 17
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
    • Relling MV, Klein TE. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther 2011; 89: 464-7.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 18
    • 85011835129 scopus 로고    scopus 로고
    • Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): A policy statement of the American College of Medical Genetics and Genomics
    • Kalia SS, Adelman K, Bale SJ, et al. Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics. Genet Med 2017; 19: 249-55.
    • (2017) Genet Med , vol.19 , pp. 249-255
    • Kalia, S.S.1    Adelman, K.2    Bale, S.J.3
  • 19
    • 85007028930 scopus 로고    scopus 로고
    • Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study
    • Dewey FE, Murray MF, Overton JD, et al. Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study. Science 2016; 354: aaf6814-1-10.
    • (2016) Science , vol.354 , pp. aaf681401-aaf681410
    • Dewey, F.E.1    Murray, M.F.2    Overton, J.D.3
  • 20
    • 84896637856 scopus 로고    scopus 로고
    • Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing
    • Van Driest SL, Shi Y, Bowton EA, et al. Clinically actionable genotypes among 10,000 patients with preemptive pharmacogenomic testing. Clin Pharmacol Ther 2014; 95: 423-31.
    • (2014) Clin Pharmacol Ther , vol.95 , pp. 423-431
    • Van Driest, S.L.1    Shi, Y.2    Bowton, E.A.3
  • 21
    • 72949132104 scopus 로고
    • Factors of risk in the development of coronary heart disease-six year follow-up experience: The Framingham Study
    • Kannel WB, Dawber TR, Kagan A, Revotskie N, Stokes J III. Factors of risk in the development of coronary heart disease-six year follow-up experience: the Framingham Study. Ann Intern Med 1961; 55: 33-50.
    • (1961) Ann Intern Med , vol.55 , pp. 33-50
    • Kannel, W.B.1    Dawber, T.R.2    Kagan, A.3    Revotskie, N.4    Stokes, J.5
  • 23
    • 0030848434 scopus 로고    scopus 로고
    • Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: The Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993
    • Chambless LE, Heiss G, Folsom AR, et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am J Epidemiol 1997; 146: 483-94.
    • (1997) Am J Epidemiol , vol.146 , pp. 483-494
    • Chambless, L.E.1    Heiss, G.2    Folsom, A.R.3
  • 24
    • 85009262100 scopus 로고    scopus 로고
    • The 21st Century Cures Act-a view from the NIH
    • Hudson KL, Collins FS. The 21st Century Cures Act-a view from the NIH. N Engl J Med 2017; 376: 111-3.
    • (2017) N Engl J Med , vol.376 , pp. 111-113
    • Hudson, K.L.1    Collins, F.S.2
  • 25
    • 85070808455 scopus 로고    scopus 로고
    • H.R 34, 114th Cong.: 21st Century Cures Act (2015-2016) Congress.gov
    • H.R. 34, 114th Cong.: 21st Century Cures Act (2015-2016). Congress.gov (https://www.congress.gov/bill/ 114th-congress/ house-bill/ 34).
  • 26
    • 84957436835 scopus 로고    scopus 로고
    • Million Veteran Program: A mega-biobank to study genetic influences on health and disease
    • Gaziano JM, Concato J, Brophy M, et al. Million Veteran Program: a mega-biobank to study genetic influences on health and disease. J Clin Epidemiol 2016; 70: 214-23.
    • (2016) J Clin Epidemiol , vol.70 , pp. 214-223
    • Gaziano, J.M.1    Concato, J.2    Brophy, M.3
  • 27
    • 83455213326 scopus 로고    scopus 로고
    • China Kadoorie Biobank of 0.5 million people: Survey methods, baseline characteristics and long-term follow-up
    • Chen Z, Chen J, Collins R, et al. China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up. Int J Epidemiol 2011; 40: 1652-66.
    • (2011) Int J Epidemiol , vol.40 , pp. 1652-1666
    • Chen, Z.1    Chen, J.2    Collins, R.3
  • 28
    • 84880059657 scopus 로고    scopus 로고
    • The Electronic Medical Records and Genomics (eMERGE) Network: Past, present, and future
    • Gottesman O, Kuivaniemi H, Tromp G, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genet Med 2013; 15: 761-71.
    • (2013) Genet Med , vol.15 , pp. 761-771
    • Gottesman, O.1    Kuivaniemi, H.2    Tromp, G.3
  • 29
    • 85127431078 scopus 로고    scopus 로고
    • Scalable and accurate deep learning with electronic health records
    • Rajkomar A, Oren E, Chen K, et al. Scalable and accurate deep learning with electronic health records. NPJ Digital Med 2018; 1(1): 18.
    • (2018) NPJ Digital Med , vol.1 , Issue.1 , pp. 18
    • Rajkomar, A.1    Oren, E.2    Chen, K.3
  • 30
    • 84968813824 scopus 로고    scopus 로고
    • Deep patient: An unsupervised representation to predict the future of patients from the electronic health records
    • Miotto R, Li L, Kidd BA, Dudley JT. Deep patient: an unsupervised representation to predict the future of patients from the electronic health records. Sci Rep 2016; 6: 26094.
    • (2016) Sci Rep , vol.6 , pp. 26094
    • Miotto, R.1    Li, L.2    Kidd, B.A.3    Dudley, J.T.4
  • 31
    • 84906250701 scopus 로고    scopus 로고
    • EMERGEing progress in genomics-the first seven years
    • Crawford DC, Crosslin DR, Tromp G, et al. eMERGEing progress in genomics-the first seven years. Front Genet 2014; 5: 184.
    • (2014) Front Genet , vol.5 , pp. 184
    • Crawford, D.C.1    Crosslin, D.R.2    Tromp, G.3
  • 32
    • 85059493084 scopus 로고    scopus 로고
    • Precision medicine approaches and the health of populations: Study design concerns and considerations
    • Galea S, Abdalla SM. Precision medicine approaches and the health of populations: study design concerns and considerations. Perspect Biol Med 2018; 61: 527-36.
    • (2018) Perspect Biol Med , vol.61 , pp. 527-536
    • Galea, S.1    Abdalla, S.M.2
  • 33
    • 84941623940 scopus 로고    scopus 로고
    • Seven questions for personalized medicine
    • Joyner MJ, Paneth N. Seven questions for personalized medicine. JAMA 2015; 314: 999-1000.
    • (2015) JAMA , vol.314 , pp. 999-1000
    • Joyner, M.J.1    Paneth, N.2
  • 34
    • 84930422966 scopus 로고    scopus 로고
    • A public health perspective on a national precision medicine cohort: Balancing long-term knowledge generation with early health benefit
    • Khoury MJ, Evans JP. A public health perspective on a national precision medicine cohort: balancing long-term knowledge generation with early health benefit. JAMA 2015; 313: 2117-8.
    • (2015) JAMA , vol.313 , pp. 2117-2118
    • Khoury, M.J.1    Evans, J.P.2
  • 35
    • 85052591990 scopus 로고    scopus 로고
    • Comparison of 2 treatment models: Precision medicine and preventive medicine
    • Psaty BM, Dekkers OM, Cooper RS. Comparison of 2 treatment models: precision medicine and preventive medicine. JAMA 2018; 320: 751-2.
    • (2018) JAMA , vol.320 , pp. 751-752
    • Psaty, B.M.1    Dekkers, O.M.2    Cooper, R.S.3
  • 36
    • 84857165460 scopus 로고    scopus 로고
    • Impact of data fragmentation across healthcare centers on the accuracy of a highthroughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus
    • Wei W-Q, Leibson CL, Ransom JE, et al. Impact of data fragmentation across healthcare centers on the accuracy of a highthroughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus. J Am Med Inform Assoc 2012; 19: 219-24.
    • (2012) J Am Med Inform Assoc , vol.19 , pp. 219-224
    • Wei, W.-Q.1    Leibson, C.L.2    Ransom, J.E.3
  • 37
    • 79955035027 scopus 로고    scopus 로고
    • Electronic medical records for genetic research: Results of the eMERGE consortium
    • Kho AN, Pacheco JA, Peissig PL, et al. Electronic medical records for genetic research: results of the eMERGE consortium. Sci Transl Med 2011; 3: 79re1.
    • (2011) Sci Transl Med , vol.3 , pp. 79re1
    • Kho, A.N.1    Pacheco, J.A.2    Peissig, P.L.3
  • 38
    • 84890107642 scopus 로고    scopus 로고
    • Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
    • Denny JC, Bastarache L, Ritchie MD, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat Biotechnol 2013; 31: 1102-10.
    • (2013) Nat Biotechnol , vol.31 , pp. 1102-1110
    • Denny, J.C.1    Bastarache, L.2    Ritchie, M.D.3
  • 39
    • 85058906993 scopus 로고    scopus 로고
    • Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
    • Giri A, Hellwege JN, Keaton JM, et al. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nat Genet 2019; 51: 51-62.
    • (2019) Nat Genet , vol.51 , pp. 51-62
    • Giri, A.1    Hellwege, J.N.2    Keaton, J.M.3
  • 40
    • 84993133873 scopus 로고    scopus 로고
    • Will precision medicine improve population health?
    • Khoury MJ, Galea S. Will precision medicine improve population health? JAMA 2016; 316: 1357-8.
    • (2016) JAMA , vol.316 , pp. 1357-1358
    • Khoury, M.J.1    Galea, S.2
  • 42
    • 85005980701 scopus 로고    scopus 로고
    • Genetic risk, adherence to a healthy lifestyle, and coronary disease
    • Khera AV, Emdin CA, Drake I, et al. Genetic risk, adherence to a healthy lifestyle, and coronary disease. N Engl J Med 2016; 375: 2349-58.
    • (2016) N Engl J Med , vol.375 , pp. 2349-2358
    • Khera, A.V.1    Emdin, C.A.2    Drake, I.3


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