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Volumn 1, Issue 21, 2016, Pages

Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity

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EID: 85069272661     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.89073     Document Type: Article
Times cited : (54)

References (30)
  • 1
    • 84971282268 scopus 로고    scopus 로고
    • Systemic sclerosis: An update in 2016
    • Desbois AC, Cacoub P. Systemic sclerosis: An update in 2016. Autoimmun Rev. 2016; 15(5):417-426.
    • (2016) Autoimmun Rev , vol.15 , Issue.5 , pp. 417-426
    • Desbois, AC1    Cacoub, P.2
  • 2
    • 84937966982 scopus 로고    scopus 로고
    • Management of systemic sclerosis-related skin disease: a review of existing and experimental therapeutic approaches
    • Volkmann ER, Furst DE. Management of systemic sclerosis-related skin disease: a review of existing and experimental therapeutic approaches. Rheum Dis Clin North Am. 2015; 41(3):399-417.
    • (2015) Rheum Dis Clin North Am , vol.41 , Issue.3 , pp. 399-417
    • Volkmann, ER1    Furst, DE.2
  • 3
    • 75749095228 scopus 로고    scopus 로고
    • A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis
    • Farina G, Lafyatis D, Lemaire R, Lafyatis R. A four-gene biomarker predicts skin disease in patients with diffuse cutaneous systemic sclerosis. Arthritis Rheum. 2010; 62(2):580-588.
    • (2010) Arthritis Rheum , vol.62 , Issue.2 , pp. 580-588
    • Farina, G1    Lafyatis, D2    Lemaire, R3    Lafyatis, R.4
  • 4
    • 84961923078 scopus 로고    scopus 로고
    • Local skin gene expression reflects both local and systemic skin disease in patients with systemic sclerosis
    • Rice LM, Stifano G, Ziemek J, Lafyatis R. Local skin gene expression reflects both local and systemic skin disease in patients with systemic sclerosis. Rheumatology (Oxford). 2016; 55(2):377-379.
    • (2016) Rheumatology (Oxford) , vol.55 , Issue.2 , pp. 377-379
    • Rice, LM1    Stifano, G2    Ziemek, J3    Lafyatis, R.4
  • 5
    • 84946024731 scopus 로고    scopus 로고
    • A longitudinal biomarker for the extent of skin disease in patients with diffuse cutaneous systemic sclerosis
    • Rice LM, et al. A longitudinal biomarker for the extent of skin disease in patients with diffuse cutaneous systemic sclerosis. Arthritis Rheumatol. 2015; 67(11):3004-3015.
    • (2015) Arthritis Rheumatol , vol.67 , Issue.11 , pp. 3004-3015
    • Rice, LM1
  • 6
    • 59649118981 scopus 로고    scopus 로고
    • Molecular framework for response to imatinib mesylate in systemic sclerosis
    • Chung L, et al. Molecular framework for response to imatinib mesylate in systemic sclerosis. Arthritis Rheum. 2009; 60(2):584-591.
    • (2009) Arthritis Rheum , vol.60 , Issue.2 , pp. 584-591
    • Chung, L1
  • 7
    • 84939440702 scopus 로고    scopus 로고
    • Nilotinib (Tasigna™) in the treatment of early diffuse systemic sclerosis: an open-label, pilot clinical trial
    • Gordon JK, et al. Nilotinib (Tasigna™) in the treatment of early diffuse systemic sclerosis: an open-label, pilot clinical trial. Arthritis Res Ther. 2015; 17:213.
    • (2015) Arthritis Res Ther , vol.17 , pp. 213
    • Gordon, JK1
  • 8
    • 84880326024 scopus 로고    scopus 로고
    • Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis
    • Hinchcliff M, et al. Molecular signatures in skin associated with clinical improvement during mycophenolate treatment in systemic sclerosis. J Invest Dermatol. 2013; 133(8):1979-1989.
    • (2013) J Invest Dermatol , vol.133 , Issue.8 , pp. 1979-1989
    • Hinchcliff, M1
  • 9
    • 84933518561 scopus 로고    scopus 로고
    • Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis
    • Chakravarty EF, et al. Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis. Arthritis Res Ther. 2015; 17:159.
    • (2015) Arthritis Res Ther , vol.17 , pp. 159
    • Chakravarty, EF1
  • 10
    • 84859760888 scopus 로고    scopus 로고
    • Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies
    • Pendergrass SA, Lemaire R, Francis IP, Mahoney JM, Lafyatis R, Whitfield ML. Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies. J Invest Dermatol. 2012; 132(5):1363-1373.
    • (2012) J Invest Dermatol , vol.132 , Issue.5 , pp. 1363-1373
    • Pendergrass, SA1    Lemaire, R2    Francis, IP3    Mahoney, JM4    Lafyatis, R5    Whitfield, ML.6
  • 11
    • 49949114547 scopus 로고    scopus 로고
    • Molecular subsets in the gene expression signatures of scleroderma skin
    • Milano A, et al. Molecular subsets in the gene expression signatures of scleroderma skin. PLoS One. 2008; 3(7):e2696.
    • (2008) PLoS One , vol.3 , Issue.7 , pp. e2696
    • Milano, A1
  • 12
    • 84940898743 scopus 로고    scopus 로고
    • Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis
    • Assassi S et al. Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis. Arthritis Rheumatol. 2015; 67(11):3016-3026.
    • (2015) Arthritis Rheumatol , vol.67 , Issue.11 , pp. 3016-3026
    • Assassi, S1
  • 13
    • 85016160000 scopus 로고    scopus 로고
    • Methods to increase reproducibility in differential gene expression via meta-analysis
    • [published online ahead of print September 14, 2016]
    • Sweeney TE, Haynes WA, Vallania F, Ioannidis JP, Khatri P. Methods to increase reproducibility in differential gene expression via meta-analysis [published online ahead of print September 14, 2016]. Nucleic Acids Res. doi: 10.1093/nar/gkw797.
    • Nucleic Acids Res
    • Sweeney, TE1    Haynes, WA2    Vallania, F3    Ioannidis, JP4    Khatri, P.5
  • 14
    • 84886849594 scopus 로고    scopus 로고
    • A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation
    • Khatri P, et al. A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation. J Exp Med. 2013; 210(11):2205-2221.
    • (2013) J Exp Med , vol.210 , Issue.11 , pp. 2205-2221
    • Khatri, P1
  • 15
    • 84902333080 scopus 로고    scopus 로고
    • SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
    • Mazur PK, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 2014; 510(7504):283-287.
    • (2014) Nature , vol.510 , Issue.7504 , pp. 283-287
    • Mazur, PK1
  • 16
    • 84901273733 scopus 로고    scopus 로고
    • A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma
    • Chen R, et al. A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma. Cancer Res. 2014; 74(10):2892-2902.
    • (2014) Cancer Res , vol.74 , Issue.10 , pp. 2892-2902
    • Chen, R1
  • 17
    • 84929629371 scopus 로고    scopus 로고
    • A comprehensive time-course-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set
    • Sweeney TE, Shidham A, Wong HR, Khatri P. A comprehensive time-course-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set. Sci Transl Med. 2015; 7(287):287ra71.
    • (2015) Sci Transl Med , vol.7 , Issue.287 , pp. 287ra71
    • Sweeney, TE1    Shidham, A2    Wong, HR3    Khatri, P.4
  • 18
    • 84983096128 scopus 로고    scopus 로고
    • Comprehensive validation of the FAIM3:PLAC8 ratio in time-matched public gene expression data
    • Sweeney TE, Khatri P. Comprehensive validation of the FAIM3:PLAC8 ratio in time-matched public gene expression data. Am J Respir Crit Care Med. 2015; 192(10):1260-1261.
    • (2015) Am J Respir Crit Care Med , vol.192 , Issue.10 , pp. 1260-1261
    • Sweeney, TE1    Khatri, P.2
  • 19
    • 84963517248 scopus 로고    scopus 로고
    • Integrated, multi-cohort analysis identifies conserved transcriptional signatures across multiple respiratory viruses
    • Andres-Terre M, et al. Integrated, multi-cohort analysis identifies conserved transcriptional signatures across multiple respiratory viruses. Immunity. 2015; 43(6):1199-1211.
    • (2015) Immunity , vol.43 , Issue.6 , pp. 1199-1211
    • Andres-Terre, M1
  • 20
    • 84959505947 scopus 로고    scopus 로고
    • Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
    • Sweeney TE, Braviak L, Tato CM, Khatri P. Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis. Lancet Respir Med. 2016; 4(3):213-224.
    • (2016) Lancet Respir Med , vol.4 , Issue.3 , pp. 213-224
    • Sweeney, TE1    Braviak, L2    Tato, CM3    Khatri, P.4
  • 21
    • 84965089714 scopus 로고    scopus 로고
    • Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases
    • Li MD, Burns TC, Morgan AA, Khatri P. Integrated multi-cohort transcriptional meta-analysis of neurodegenerative diseases. Acta Neuropathol Commun. 2014; 2:93.
    • (2014) Acta Neuropathol Commun , vol.2 , pp. 93
    • Li, MD1    Burns, TC2    Morgan, AA3    Khatri, P.4
  • 22
    • 0038004796 scopus 로고    scopus 로고
    • Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
    • Mori Y, Chen SJ, Varga J. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts. Arthritis Rheum. 2003; 48(7):1964-1978.
    • (2003) Arthritis Rheum , vol.48 , Issue.7 , pp. 1964-1978
    • Mori, Y1    Chen, SJ2    Varga, J.3
  • 23
    • 34548400259 scopus 로고    scopus 로고
    • A systems biology approach for pathway level analysis
    • Draghici S, et al. A systems biology approach for pathway level analysis. Genome Res. 2007; 17(10):1537-1545.
    • (2007) Genome Res , vol.17 , Issue.10 , pp. 1537-1545
    • Draghici, S1
  • 24
    • 84922224910 scopus 로고    scopus 로고
    • Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms
    • Mahoney JM, et al. Systems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms. PLoS Comput Biol. 2015; 11(1):e1004005.
    • (2015) PLoS Comput Biol , vol.11 , Issue.1 , pp. e1004005
    • Mahoney, JM1
  • 25
    • 23644448110 scopus 로고    scopus 로고
    • Scleroderma, fibroblasts, signaling, and excessive extracellular matrix
    • Ihn H. Scleroderma, fibroblasts, signaling, and excessive extracellular matrix. Curr Rheumatol Rep. 2005; 7(2):156-162.
    • (2005) Curr Rheumatol Rep , vol.7 , Issue.2 , pp. 156-162
    • Ihn, H.1
  • 26
    • 0037310629 scopus 로고    scopus 로고
    • Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice
    • Planque S, et al. Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice. FASEB J. 2003; 17(2):136-143.
    • (2003) FASEB J , vol.17 , Issue.2 , pp. 136-143
    • Planque, S1
  • 27
    • 84861123691 scopus 로고    scopus 로고
    • Ten years of pathway analysis: current approaches and outstanding challenges
    • Khatri P, Sirota M, Butte AJ. Ten years of pathway analysis: current approaches and outstanding challenges. PLoS Comput Biol. 2012; 8(2):e1002375.
    • (2012) PLoS Comput Biol , vol.8 , Issue.2 , pp. e1002375
    • Khatri, P1    Sirota, M2    Butte, AJ.3
  • 28
    • 53149135477 scopus 로고    scopus 로고
    • Key issues in conducting a meta-analysis of gene expression microarray datasets
    • Ramasamy A, Mondry A, Holmes CC, Altman DG. Key issues in conducting a meta-analysis of gene expression microarray datasets. PLoS Med. 2008; 5(9):e184.
    • (2008) PLoS Med , vol.5 , Issue.9 , pp. e184
    • Ramasamy, A1    Mondry, A2    Holmes, CC3    Altman, DG.4
  • 29
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Stat Soc Series B Stat Methodol. 1995; 57(1):289-300.
    • (1995) J R Stat Soc Series B Stat Methodol , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y1    Hochberg, Y.2


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