Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis

Inflammatory Bowel Diseases

Volumn 25, Issue 9, 2019, Pages 1450-1461

  Chen, Liang ^a,b   Sun, Mingming ^a,b   Wu, Wei ^a,b   Yang, Wenjing ^a,b   Huang, Xiangsheng ^a   Xiao, Yi ^a   Ma, Chunyan ^a   Xu, Leiqi ^a   Yao, Suxia ^a   Liu, Zhanju ^b   Cong, Yingzi ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b TONGJI UNIVERSITY   (China)

Author keywords

butyrate; colitis; IL 10; Th1 cells; Th17 cells

Indexed keywords

ANTIGEN; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BUTYRIC ACID; CBIR1 PROTEIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 43; GAMMA INTERFERON; HISTONE DEACETYLASE; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR ANTIBODY; INTERLEUKIN 17; PROTEIN ANTIBODY; RAG1 PROTEIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; BUTYRIC ACID DERIVATIVE; IL10 PROTEIN, MOUSE; INTERLEUKIN 10; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME INHIBITION; IN VIVO STUDY; INTESTINE FLORA; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAG1 GENE; REGULATORY MECHANISM; TH1 CELL; TH17 CELL; ANIMAL; C57BL MOUSE; DRUG EFFECT; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; BUTYRATES; CELL DIFFERENTIATION; COLITIS; GASTROINTESTINAL MICROBIOME; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-17; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH17 CELLS;

EID: 85068142395     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1093/ibd/izz046     Document Type: Article

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