Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway

Mucosal Immunology

Volumn 8, Issue 1, 2015, Pages 80-93

  Park, J ^a   Kim, M ^a   Kang, S G ^a   Jannasch, A H ^b   Cooper, B ^b   Patterson, J ^b   Kim, C H ^a,c,d  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c PURDUE UNIVERSITY   (United States)

^d Purdue University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; CD3 ANTIGEN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 41; G PROTEIN COUPLED RECEPTOR 43; GAMMA INTERFERON; HISTONE DEACETYLASE; INTERLEUKIN 10; INTERLEUKIN 17; MAMMALIAN TARGET OF RAPAMYCIN; PROPIONIC ACID; S6 KINASE; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; TARGET OF RAPAMYCIN KINASE; VOLATILE FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CITROBACTER RODENTIUM; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; INTRACELLULAR SIGNALING; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; TH1 CELL; TH17 CELL; WEIGHT CHANGE; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; DRUG EFFECTS; ENTEROBACTERIACEAE INFECTION; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

ACETATES; ANIMALS; CELL DIFFERENTIATION; CELLULAR MICROENVIRONMENT; CITROBACTER RODENTIUM; ENTEROBACTERIACEAE INFECTIONS; FATTY ACIDS, VOLATILE; HISTONE DEACETYLASES; IMMUNE TOLERANCE; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS; TOR SERINE-THREONINE KINASES;

EID: 84922163095     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2014.44     Document Type: Article

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