Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats

BMC Gastroenterology

Volumn 16, Issue 1, 2016, Pages

  Zhang, Mingming ^a,b   Zhou, Qian ^c   Dorfman, Robert G ^d   Huang, Xiaoli ^e   Fan, Tingting ^c   Zhang, Hao ^f   Zhang, Jun ^b   Yu, Chenggong ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d NORTHWESTERN UNIVERSITY   (United States)

^e Department of Gastroenterology   (China)

^f NANJING UNIVERSITY   (China)

Author keywords

Butyrate; Cytokines; Inflammatory bowel disease; Th17; Treg

Indexed keywords

BUTYRIC ACID; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; SHORT CHAIN FATTY ACID; ANTIINFLAMMATORY AGENT; BUTYRIC ACID DERIVATIVE; CYTOKINE; VOLATILE FATTY ACID;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LYMPHOCYTE DIFFERENTIATION; MALE; MONOCYTE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; REGULATORY T LYMPHOCYTE; SPLEEN CELL; TH17 CELL; ULCERATIVE COLITIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; BODY WEIGHT; CELL CULTURE; CELL DIFFERENTIATION; COLITIS, ULCERATIVE; COLON; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; SPRAGUE DAWLEY RAT;

ADULT; ANIMALS; ANTI-INFLAMMATORY AGENTS; BODY WEIGHT; BUTYRATES; CELL DIFFERENTIATION; CELLS, CULTURED; COLITIS, ULCERATIVE; COLON; CYTOKINES; DISEASE MODELS, ANIMAL; FATTY ACIDS, VOLATILE; FEMALE; HUMANS; INTERLEUKIN-17; MALE; MIDDLE AGED; RATS, SPRAGUE-DAWLEY; T-LYMPHOCYTES, REGULATORY;

EID: 84979651505     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/s12876-016-0500-x     Document Type: Article

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