메뉴 건너뛰기




Volumn 163, Issue , 2019, Pages 113-134

Marine glycan-derived therapeutics in China

Author keywords

Chitosan ester (PS916); Fucoidan (FPS); Marine glycan based drugs; Oligomannurate chromium sodium (HS203); Polyguluronate sulfate sodium (PGS); Polymannuroguluronate sulfate (911); Propylene glycol alginate sodium sulfate (PSS); Propylene glycol mannuronate sulfate (PGMS); Sodium oligomannurarate (GV971)

Indexed keywords

ALGINIC ACID; CHITIN ESTER; CHITOSAN DERIVATIVE; FUCOIDIN; GLYCAN DERIVATIVE; OLIGOMANNURONATE CHROMIUM SODIUM; POLYGULURONATE SULFATE SODIUM; PROPYLENE GLYCOL ALGINATE SODIUM SULFATE; PROPYLENE GLYCOL MANNURONATE SULFATE; SODIUM OLIGOMANNURARATE; UNCLASSIFIED DRUG; POLYSACCHARIDE;

EID: 85063347658     PISSN: 18771173     EISSN: 18780814     Source Type: Book Series    
DOI: 10.1016/bs.pmbts.2019.02.006     Document Type: Chapter
Times cited : (23)

References (136)
  • 1
    • 85032827087 scopus 로고    scopus 로고
    • Overview on the antiviral activities and mechanisms of marine polysaccharides from seaweeds
    • Shi, Q., Wang, A., Lu, Z., Qin, C., Hu, J., Yin, J., Overview on the antiviral activities and mechanisms of marine polysaccharides from seaweeds. Carbohydr Res 453–454 (2017), 1–9.
    • (2017) Carbohydr Res , vol.453-454 , pp. 1-9
    • Shi, Q.1    Wang, A.2    Lu, Z.3    Qin, C.4    Hu, J.5    Yin, J.6
  • 2
    • 84930660813 scopus 로고    scopus 로고
    • Marine polysaccharides from algae with potential biomedical applications
    • de Jesus Raposo, M.F., de Morais, A.M., de Morais, R.M., Marine polysaccharides from algae with potential biomedical applications. Mar Drugs 13:5 (2015), 2967–3028.
    • (2015) Mar Drugs , vol.13 , Issue.5 , pp. 2967-3028
    • de Jesus Raposo, M.F.1    de Morais, A.M.2    de Morais, R.M.3
  • 3
    • 84903819687 scopus 로고    scopus 로고
    • Anticoagulant motifs of marine sulfated glycans
    • Pomin, V.H., Anticoagulant motifs of marine sulfated glycans. Glycoconj J 31:5 (2014), 341–344.
    • (2014) Glycoconj J , vol.31 , Issue.5 , pp. 341-344
    • Pomin, V.H.1
  • 4
    • 79957613570 scopus 로고    scopus 로고
    • An antithrombin-dependent sulfated polysaccharide isolated from the green alga Caulerpa cupressoides has in vivo anti-and prothrombotic effects
    • Rodrigues, J.A.G., Queiroz, I.N.L.D., Quinderé, A.L.G., Vairo, B.C., Mourão, P.A.D.S., Benevides, N.M.B., An antithrombin-dependent sulfated polysaccharide isolated from the green alga Caulerpa cupressoides has in vivo anti-and prothrombotic effects. Cienc Rural 41:4 (2011), 634–639.
    • (2011) Cienc Rural , vol.41 , Issue.4 , pp. 634-639
    • Rodrigues, J.A.G.1    Queiroz, I.N.L.D.2    Quinderé, A.L.G.3    Vairo, B.C.4    Mourão, P.A.D.S.5    Benevides, N.M.B.6
  • 5
    • 84878407280 scopus 로고    scopus 로고
    • The fucoidans from brown algae of far-eastern seas: anti-tumor activity and structure–function relationship
    • Vishchuk, O.S., Ermakova, S.P., Zvyagintseva, T.N., The fucoidans from brown algae of far-eastern seas: anti-tumor activity and structure–function relationship. Food Chem 141:2 (2013), 1211–1217.
    • (2013) Food Chem , vol.141 , Issue.2 , pp. 1211-1217
    • Vishchuk, O.S.1    Ermakova, S.P.2    Zvyagintseva, T.N.3
  • 6
    • 34147092057 scopus 로고    scopus 로고
    • Antioxidant activities of sulfated polysaccharides from brown and red seaweeds
    • Souza, M.C.R.D., Marques, C.T., Dore, C.M.G., Rocha, H.A.O., Leite, E.L., Antioxidant activities of sulfated polysaccharides from brown and red seaweeds. J Appl Psychol 19:2 (2007), 153–160.
    • (2007) J Appl Psychol , vol.19 , Issue.2 , pp. 153-160
    • Souza, M.C.R.D.1    Marques, C.T.2    Dore, C.M.G.3    Rocha, H.A.O.4    Leite, E.L.5
  • 8
    • 78650557997 scopus 로고    scopus 로고
    • Evaluation of in vitro antioxidant and antibacterial activities of Laminaria japonica polysaccharides
    • Li, L., Li, L., Guo, C., Evaluation of in vitro antioxidant and antibacterial activities of Laminaria japonica polysaccharides. J Med Plant Res 4:21 (2010), 2194–2198.
    • (2010) J Med Plant Res , vol.4 , Issue.21 , pp. 2194-2198
    • Li, L.1    Li, L.2    Guo, C.3
  • 9
    • 84908610688 scopus 로고    scopus 로고
    • Fucoidan—a α-d-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy
    • Kumar, T.V., Lakshmanasenthil, S., Geetharamani, D., Marudhupandi, T., Suja, G., Suganya, P., Fucoidan—a α-d-glucosidase inhibitor from Sargassum wightii with relevance to type 2 diabetes mellitus therapy. Int J Biol Macromol 72 (2015), 1044–1047.
    • (2015) Int J Biol Macromol , vol.72 , pp. 1044-1047
    • Kumar, T.V.1    Lakshmanasenthil, S.2    Geetharamani, D.3    Marudhupandi, T.4    Suja, G.5    Suganya, P.6
  • 10
    • 85007454275 scopus 로고    scopus 로고
    • Marine algae as a potential source for anti-obesity agents
    • Wan-Loy, C., Siew-Moi, P., Marine algae as a potential source for anti-obesity agents. Mar Drugs 14:12 (2016), 222–240.
    • (2016) Mar Drugs , vol.14 , Issue.12 , pp. 222-240
    • Wan-Loy, C.1    Siew-Moi, P.2
  • 11
    • 84921280672 scopus 로고    scopus 로고
    • The beneficial properties of marine polysaccharides in alleviation of allergic responses
    • Vo, T.S., Ngo, D.H., Kang, K.H., Jung, W.K., Kim, S.K., The beneficial properties of marine polysaccharides in alleviation of allergic responses. Mol Nutr Food Res 59:1 (Jan 2015), 129–138.
    • (2015) Mol Nutr Food Res , vol.59 , Issue.1 , pp. 129-138
    • Vo, T.S.1    Ngo, D.H.2    Kang, K.H.3    Jung, W.K.4    Kim, S.K.5
  • 12
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki, A., Medzhitov, R., Regulation of adaptive immunity by the innate immune system. Science, 327(5963), 2010, 291.
    • (2010) Science , vol.327 , Issue.5963 , pp. 291
    • Iwasaki, A.1    Medzhitov, R.2
  • 13
    • 85044944700 scopus 로고    scopus 로고
    • Polyguluronate sulfate (PGS) attenuates immunological liver injury in vitro and in vivo
    • Gao, Y., Liu, W., Wang, W., Zhao, X., Wang, F., Polyguluronate sulfate (PGS) attenuates immunological liver injury in vitro and in vivo. Int J Biol Macromol 114 (2018), 592–598.
    • (2018) Int J Biol Macromol , vol.114 , pp. 592-598
    • Gao, Y.1    Liu, W.2    Wang, W.3    Zhao, X.4    Wang, F.5
  • 14
    • 84921403651 scopus 로고    scopus 로고
    • Antioxidative, hypolipidemic, and anti-inflammatory activities of sulfated polysaccharides from Monostroma nitidum
    • Hoang, M.H., Kim, J.-Y., Lee, J.H., You, S., Lee, S.-J., Antioxidative, hypolipidemic, and anti-inflammatory activities of sulfated polysaccharides from Monostroma nitidum. Food Sci Biotechnol 24:1 (2015), 199–205.
    • (2015) Food Sci Biotechnol , vol.24 , Issue.1 , pp. 199-205
    • Hoang, M.H.1    Kim, J.-Y.2    Lee, J.H.3    You, S.4    Lee, S.-J.5
  • 15
    • 79955748482 scopus 로고    scopus 로고
    • Rising from the sea: correlations between sulfated polysaccharides and salinity in plants
    • Aquino, R.S., Grativol, C., Mourao, P.A., Rising from the sea: correlations between sulfated polysaccharides and salinity in plants. PLoS One, 6(4), 2011, e18862.
    • (2011) PLoS One , vol.6 , Issue.4
    • Aquino, R.S.1    Grativol, C.2    Mourao, P.A.3
  • 16
    • 84929518279 scopus 로고    scopus 로고
    • Salinity-induced anti-angiogenesis activities and structural changes of the polysaccharides from cultured Cordyceps Militaris
    • Zeng, Y., Han, Z., Qiu, P., et al. Salinity-induced anti-angiogenesis activities and structural changes of the polysaccharides from cultured Cordyceps Militaris. PLoS One., 9(9), 2014, e103880.
    • (2014) PLoS One. , vol.9 , Issue.9
    • Zeng, Y.1    Han, Z.2    Qiu, P.3
  • 17
    • 85063103784 scopus 로고    scopus 로고
    • Heparin: an essential drug for modern medicine
    • Hao, C., Xu, H., Yu, L., Zhang, L., Heparin: an essential drug for modern medicine. Prog Mol Biol Transl Sci 163 (2019), 1–19.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 1-19
    • Hao, C.1    Xu, H.2    Yu, L.3    Zhang, L.4
  • 18
    • 85063203346 scopus 로고    scopus 로고
    • Low molecular weight heparins and their clinical applications
    • Hao, C., Sun, M., Wang, H., Zhang, L., Wang, W., Low molecular weight heparins and their clinical applications. Prog Mol Biol Transl Sci 163 (2019), 21–39.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 21-39
    • Hao, C.1    Sun, M.2    Wang, H.3    Zhang, L.4    Wang, W.5
  • 19
    • 85063102370 scopus 로고    scopus 로고
    • Heparinoids danaparoid and sulodexide as clinically used drugs
    • Dou, H., Song, A., Jia, S., Zhang, L., Heparinoids danaparoid and sulodexide as clinically used drugs. Prog Mol Biol Transl Sci 163 (2019), 55–74.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 55-74
    • Dou, H.1    Song, A.2    Jia, S.3    Zhang, L.4
  • 20
    • 85007153711 scopus 로고    scopus 로고
    • A century of heparin: past, present and future
    • Hemker, H.C., A century of heparin: past, present and future. J Thromb Haemost 14:12 (Dec 2016), 2329–2338.
    • (2016) J Thromb Haemost , vol.14 , Issue.12 , pp. 2329-2338
    • Hemker, H.C.1
  • 21
    • 77749298749 scopus 로고    scopus 로고
    • Oversulfated chondroitin sulfate is not the sole contaminant in heparin
    • Pan, J., Qian, Y., Zhou, X., et al. Oversulfated chondroitin sulfate is not the sole contaminant in heparin. Nat Biotechnol, 28(3), 2010, 203.
    • (2010) Nat Biotechnol , vol.28 , Issue.3 , pp. 203
    • Pan, J.1    Qian, Y.2    Zhou, X.3
  • 22
    • 85050891991 scopus 로고    scopus 로고
    • Glycosaminoglycans in development, health and disease. Preface
    • Zhang, L., Glycosaminoglycans in development, health and disease. Preface. Prog Mol Biol Transl Sci 93 (2010), xvii–xviii.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. xvii-xviii
    • Zhang, L.1
  • 23
    • 84871799778 scopus 로고    scopus 로고
    • The antiviral activities and mechanisms of marine polysaccharides: an overview
    • Wang, W., Wang, S., Guan, H., The antiviral activities and mechanisms of marine polysaccharides: an overview. Mar Drugs 10:12 (2012), 2795–2816.
    • (2012) Mar Drugs , vol.10 , Issue.12 , pp. 2795-2816
    • Wang, W.1    Wang, S.2    Guan, H.3
  • 24
    • 84925878913 scopus 로고    scopus 로고
    • Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death via Bcl-2/Bax signal pathway
    • Hao, C., Gao, L., Zhang, Y., et al. Acetylated chitosan oligosaccharides act as antagonists against glutamate-induced PC12 cell death via Bcl-2/Bax signal pathway. Mar Drugs 13:3 (2015), 1267–1289.
    • (2015) Mar Drugs , vol.13 , Issue.3 , pp. 1267-1289
    • Hao, C.1    Gao, L.2    Zhang, Y.3
  • 25
    • 85063213392 scopus 로고    scopus 로고
    • Efficacy of heparinoid PSS in treating cardiovascular diseases and beyond—a review of 31 years clinical experiences in China
    • Shan, M., Feng, N., Zhang, L., Efficacy of heparinoid PSS in treating cardiovascular diseases and beyond—a review of 31 years clinical experiences in China. Prog Mol Biol Transl Sci 163 (2019), 75–93.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 75-93
    • Shan, M.1    Feng, N.2    Zhang, L.3
  • 26
    • 85063356637 scopus 로고    scopus 로고
    • Use of fucoidan to treat renal diseases: a review of 15 years of clinic studies
    • Wang, J., Geng, L., Yue, Y., Zhang, Q., Use of fucoidan to treat renal diseases: a review of 15 years of clinic studies. Prog Mol Biol Transl Sci 163 (2019), 95–111.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 95-111
    • Wang, J.1    Geng, L.2    Yue, Y.3    Zhang, Q.4
  • 27
    • 77749298749 scopus 로고    scopus 로고
    • Oversulfated chondroitin sulfate is not the sole contaminant in heparin
    • [author reply 207–211]
    • Pan, J., Qian, Y., Zhou, X., et al. Oversulfated chondroitin sulfate is not the sole contaminant in heparin. Nat Biotechnol 28:3 (Mar 2010), 203–207 [author reply 207–211].
    • (2010) Nat Biotechnol , vol.28 , Issue.3 , pp. 203-207
    • Pan, J.1    Qian, Y.2    Zhou, X.3
  • 28
    • 61449171129 scopus 로고    scopus 로고
    • Lessons learned from the contamination of heparin
    • Liu, H., Zhang, Z., Linhardt, R.J., Lessons learned from the contamination of heparin. Nat Prod Rep 26:3 (Mar 2009), 313–321.
    • (2009) Nat Prod Rep , vol.26 , Issue.3 , pp. 313-321
    • Liu, H.1    Zhang, Z.2    Linhardt, R.J.3
  • 29
    • 77953644228 scopus 로고    scopus 로고
    • Chemically oversulfated glycosaminoglycans are potent modulators of contact system activation and different cell signaling pathways
    • Pan, J., Qian, Y., Zhou, X., Lu, H., Ramacciotti, E., Zhang, L., Chemically oversulfated glycosaminoglycans are potent modulators of contact system activation and different cell signaling pathways. J Biol Chem 285:30 (2010), 22966–22975.
    • (2010) J Biol Chem , vol.285 , Issue.30 , pp. 22966-22975
    • Pan, J.1    Qian, Y.2    Zhou, X.3    Lu, H.4    Ramacciotti, E.5    Zhang, L.6
  • 30
    • 77749277014 scopus 로고    scopus 로고
    • Identification of chemically sulfated/desulfated glycosaminoglycans in contaminated heparins and development of a simple assay for the detection of most contaminants in heparin
    • Pan, J., Qian, Y., Zhou, X., et al. Identification of chemically sulfated/desulfated glycosaminoglycans in contaminated heparins and development of a simple assay for the detection of most contaminants in heparin. Glycobiol Insights 2010:2 (2010), 1–12.
    • (2010) Glycobiol Insights , vol.2010 , Issue.2 , pp. 1-12
    • Pan, J.1    Qian, Y.2    Zhou, X.3
  • 31
    • 45149118311 scopus 로고    scopus 로고
    • Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events
    • Guerrini, M., Beccati, D., Shriver, Z., et al. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nat Biotechnol 26:6 (Jun 2008), 669–675.
    • (2008) Nat Biotechnol , vol.26 , Issue.6 , pp. 669-675
    • Guerrini, M.1    Beccati, D.2    Shriver, Z.3
  • 32
    • 77958183682 scopus 로고    scopus 로고
    • Molecular mechanism underlines heparin-induced thrombocytopenia and thrombosis
    • Qian, Y., Pan, J., Zhou, X., Weiser, P., Lu, H., Zhang, L., Molecular mechanism underlines heparin-induced thrombocytopenia and thrombosis. Prog Mol Biol Transl Sci 93 (2010), 395–421.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 395-421
    • Qian, Y.1    Pan, J.2    Zhou, X.3    Weiser, P.4    Lu, H.5    Zhang, L.6
  • 33
    • 77953632789 scopus 로고    scopus 로고
    • Contaminated heparin-affected patient plasmas are associated with activated contact systems
    • Qian, Y., Pan, J., Zhou, X., et al. Contaminated heparin-affected patient plasmas are associated with activated contact systems. Clin Appl Thromb Hemost 16:3 (2010), 261–265.
    • (2010) Clin Appl Thromb Hemost , vol.16 , Issue.3 , pp. 261-265
    • Qian, Y.1    Pan, J.2    Zhou, X.3
  • 34
    • 77958176290 scopus 로고    scopus 로고
    • Glycosaminoglycans and activated contact system in cancer patient plasmas
    • Pan, J., Qian, Y., Weiser, P., et al. Glycosaminoglycans and activated contact system in cancer patient plasmas. Prog Mol Biol Transl Sci 93 (2010), 473–495.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 473-495
    • Pan, J.1    Qian, Y.2    Weiser, P.3
  • 35
    • 84870844193 scopus 로고    scopus 로고
    • Novel procedures for the extraction of fucoidan from brown algae
    • Hahn, T., Lang, S., Ulber, R., Muffler, K., Novel procedures for the extraction of fucoidan from brown algae. Process Biochem 47:12 (2012), 1691–1698.
    • (2012) Process Biochem , vol.47 , Issue.12 , pp. 1691-1698
    • Hahn, T.1    Lang, S.2    Ulber, R.3    Muffler, K.4
  • 36
    • 79961026340 scopus 로고    scopus 로고
    • Microwave-assisted extraction of sulfated polysaccharides (fucoidan) from brown seaweed
    • Rodriguez-Jasso, R.M., Mussatto, S.I., Pastrana, L., Aguilar, C.N., Teixeira, J.A., Microwave-assisted extraction of sulfated polysaccharides (fucoidan) from brown seaweed. Carbohydr Polym 86:3 (2011), 1137–1144.
    • (2011) Carbohydr Polym , vol.86 , Issue.3 , pp. 1137-1144
    • Rodriguez-Jasso, R.M.1    Mussatto, S.I.2    Pastrana, L.3    Aguilar, C.N.4    Teixeira, J.A.5
  • 37
    • 34247868925 scopus 로고    scopus 로고
    • Characterization of polysaccharides extracted from brown seaweeds
    • Rioux, L.E., Turgeon, S.L., Beaulieu, M., Characterization of polysaccharides extracted from brown seaweeds. Carbohydr Polym 69:3 (2007), 530–537.
    • (2007) Carbohydr Polym , vol.69 , Issue.3 , pp. 530-537
    • Rioux, L.E.1    Turgeon, S.L.2    Beaulieu, M.3
  • 38
    • 85063315573 scopus 로고    scopus 로고
    • n.d. A method for extracting brown algae polysaccharide sulfate. CN Patent 200710014573.X.2007-9-19.
    • Li P, Chen X, Xing R, Yu H, Liu S. n.d. A method for extracting brown algae polysaccharide sulfate. CN Patent 200710014573.X.2007-9-19.
    • Li, P.1    Chen, X.2    Xing, R.3    Yu, H.4    Liu, S.5
  • 39
    • 0037488481 scopus 로고    scopus 로고
    • Effects of fucoidan on chronic renal failure in rats
    • Zhang, Q., Li, Z., Xu, Z., Niu, X., Zhang, H., Effects of fucoidan on chronic renal failure in rats. Planta Med, 69(6), 2003, 537.
    • (2003) Planta Med , vol.69 , Issue.6 , pp. 537
    • Zhang, Q.1    Li, Z.2    Xu, Z.3    Niu, X.4    Zhang, H.5
  • 40
    • 85063325899 scopus 로고    scopus 로고
    • Observation of the curative effect of Shen Hai Kang in the treatment of chronic renal failure
    • Bian, L., Xia, P., La, Y., Observation of the curative effect of Shen Hai Kang in the treatment of chronic renal failure. Chin J Integr Tradit West Nephrol 5:1 (2004), 45–46.
    • (2004) Chin J Integr Tradit West Nephrol , vol.5 , Issue.1 , pp. 45-46
    • Bian, L.1    Xia, P.2    La, Y.3
  • 41
    • 21344470130 scopus 로고    scopus 로고
    • Inhibitory effect of fucoidan on the adhesion of adenocarcinoma cells to fibronectin
    • Liu, J.M., Bignon, J., Haroun-Bouhedja, F., et al. Inhibitory effect of fucoidan on the adhesion of adenocarcinoma cells to fibronectin. Anticancer Res, 25(3B), 2005, 2129.
    • (2005) Anticancer Res , vol.25 , Issue.3B , pp. 2129
    • Liu, J.M.1    Bignon, J.2    Haroun-Bouhedja, F.3
  • 42
    • 79551626046 scopus 로고    scopus 로고
    • Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
    • Ikeguchi, M., Yamamoto, M., Arai, Y., et al. Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer. Oncol Lett 2:2 (2011), 319–322.
    • (2011) Oncol Lett , vol.2 , Issue.2 , pp. 319-322
    • Ikeguchi, M.1    Yamamoto, M.2    Arai, Y.3
  • 43
    • 84945932924 scopus 로고    scopus 로고
    • Fucoidan elevates microRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells
    • Yan, M.D., Yao, C.J., Chow, J.M., et al. Fucoidan elevates microRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells. Mar Drugs 13:10 (2015), 6099–6116.
    • (2015) Mar Drugs , vol.13 , Issue.10 , pp. 6099-6116
    • Yan, M.D.1    Yao, C.J.2    Chow, J.M.3
  • 44
    • 85049095377 scopus 로고    scopus 로고
    • Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice
    • Xu, Y., Xu, J., Ge, K., Tian, Q., Zhao, P., Guo, Y., Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice. Int J Biol Macromol 118:pt A (2018), 365–374.
    • (2018) Int J Biol Macromol , vol.118 , pp. 365-374
    • Xu, Y.1    Xu, J.2    Ge, K.3    Tian, Q.4    Zhao, P.5    Guo, Y.6
  • 45
    • 85039696941 scopus 로고    scopus 로고
    • Comparative study of the effect of different fucoidans from Sargassum maclurei and Saccharina japonica on FGFs/FGFR signaling activation in BaF3 cells
    • Geng, L., Hou, N., Zhang, M., et al. Comparative study of the effect of different fucoidans from Sargassum maclurei and Saccharina japonica on FGFs/FGFR signaling activation in BaF3 cells. Int J Biol Macromol 107:Pt B (2018), 2429–2435.
    • (2018) Int J Biol Macromol , vol.107 , pp. 2429-2435
    • Geng, L.1    Hou, N.2    Zhang, M.3
  • 46
    • 85026834779 scopus 로고    scopus 로고
    • The structure property and endothelial protective activity of fucoidan from Laminaria japonica
    • Chen, A., Ying, L., Liu, J., et al. The structure property and endothelial protective activity of fucoidan from Laminaria japonica. Int J Biol Macromol 105:Pt 2 (2017), 1421–1429.
    • (2017) Int J Biol Macromol , vol.105 , pp. 1421-1429
    • Chen, A.1    Ying, L.2    Liu, J.3
  • 47
    • 84892381888 scopus 로고    scopus 로고
    • Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects
    • Fedorov, S.N., Ermakova, S.P., Zvyagintseva, T.N., Stonik, V.A., Anticancer and cancer preventive properties of marine polysaccharides: some results and prospects. Mar Drugs 11:12 (2013), 4876–4901.
    • (2013) Mar Drugs , vol.11 , Issue.12 , pp. 4876-4901
    • Fedorov, S.N.1    Ermakova, S.P.2    Zvyagintseva, T.N.3    Stonik, V.A.4
  • 48
    • 84969508719 scopus 로고    scopus 로고
    • Are multifunctional marine polysaccharides a myth or reality?
    • Ermakova, S., Kusaykin, M., Trincone, A., Tatiana, Z., Are multifunctional marine polysaccharides a myth or reality?. Front Chem, 3, 2015, 39.
    • (2015) Front Chem , vol.3 , pp. 39
    • Ermakova, S.1    Kusaykin, M.2    Trincone, A.3    Tatiana, Z.4
  • 49
    • 85046743527 scopus 로고    scopus 로고
    • Marine polysaccharides attenuate metabolic syndrome by fermentation products and altering gut microbiota: an overview
    • Wang, X., Wang, X., Jiang, H., et al. Marine polysaccharides attenuate metabolic syndrome by fermentation products and altering gut microbiota: an overview. Carbohydr Polym 195 (Sep 1 2018), 601–612.
    • (2018) Carbohydr Polym , vol.195 , pp. 601-612
    • Wang, X.1    Wang, X.2    Jiang, H.3
  • 50
    • 85029513905 scopus 로고    scopus 로고
    • Marine polysaccharides: therapeutic efficacy and biomedical applications
    • Lee, Y.E., Kim, H., Seo, C., et al. Marine polysaccharides: therapeutic efficacy and biomedical applications. Arch Pharm Res 40:9 (Sep 2017), 1006–1020.
    • (2017) Arch Pharm Res , vol.40 , Issue.9 , pp. 1006-1020
    • Lee, Y.E.1    Kim, H.2    Seo, C.3
  • 52
    • 84907148468 scopus 로고    scopus 로고
    • Anti-HIV activity of fucoidans from three brown seaweed species
    • Thuy, T.T.T., Ly, B.M., Van, T.T.T., et al. Anti-HIV activity of fucoidans from three brown seaweed species. Carbohydr Polym, 115, 2015, 122.
    • (2015) Carbohydr Polym , vol.115 , pp. 122
    • Thuy, T.T.T.1    Ly, B.M.2    Van, T.T.T.3
  • 53
    • 84923261249 scopus 로고    scopus 로고
    • Fucoidan from Fucus vesiculosus protects against alcohol-induced liver damage by modulating inflammatory mediators in mice and HepG2 cells
    • Lim, J.D., Lee, S.R., Kim, T., et al. Fucoidan from Fucus vesiculosus protects against alcohol-induced liver damage by modulating inflammatory mediators in mice and HepG2 cells. Mar Drugs 13:2 (2015), 1051–1067.
    • (2015) Mar Drugs , vol.13 , Issue.2 , pp. 1051-1067
    • Lim, J.D.1    Lee, S.R.2    Kim, T.3
  • 54
    • 84962674706 scopus 로고    scopus 로고
    • Pretreatment with fucoidan from Fucus vesiculosus protected against ConA-induced acute liver injury by inhibiting both intrinsic and extrinsic apoptosis
    • Li, J., Chen, K., Li, S., et al. Pretreatment with fucoidan from Fucus vesiculosus protected against ConA-induced acute liver injury by inhibiting both intrinsic and extrinsic apoptosis. PLoS One, 11(4), 2016, e0152570.
    • (2016) PLoS One , vol.11 , Issue.4
    • Li, J.1    Chen, K.2    Li, S.3
  • 55
    • 50949098274 scopus 로고    scopus 로고
    • Fucoidan: structure and bioactivity
    • Li, B., Lu, F., Wei, X., Zhao, R., Fucoidan: structure and bioactivity. Molecules 13:8 (2008), 1671–1695.
    • (2008) Molecules , vol.13 , Issue.8 , pp. 1671-1695
    • Li, B.1    Lu, F.2    Wei, X.3    Zhao, R.4
  • 56
    • 85063341381 scopus 로고    scopus 로고
    • 40 cases of chronic renal failure treated by Haikunshenxi capsules
    • Du, L., 40 cases of chronic renal failure treated by Haikunshenxi capsules. Shaanxi J Tradit Chin Med 30:12 (2009), 1582–1583.
    • (2009) Shaanxi J Tradit Chin Med , vol.30 , Issue.12 , pp. 1582-1583
    • Du, L.1
  • 57
    • 85063340511 scopus 로고    scopus 로고
    • Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure and its antioxidant mechanism
    • Shi, D., Study on clinical effect of Haikunshenxi capsules in treatment of patients with chronic renal failure and its antioxidant mechanism. J Clin Exp Med 14:4 (2015), 307–310.
    • (2015) J Clin Exp Med , vol.14 , Issue.4 , pp. 307-310
    • Shi, D.1
  • 58
    • 33751548703 scopus 로고    scopus 로고
    • Bioanalysis and pharmacokinetics of chitosan ester in rabbit serum by HPLC with postcolumn fluorescence derivatization
    • Han, Y., Lv, Z., Jiang, T., Wang, Y., Bioanalysis and pharmacokinetics of chitosan ester in rabbit serum by HPLC with postcolumn fluorescence derivatization. J Chromatogr B 845:1 (2007), 138–142.
    • (2007) J Chromatogr B , vol.845 , Issue.1 , pp. 138-142
    • Han, Y.1    Lv, Z.2    Jiang, T.3    Wang, Y.4
  • 59
    • 85027260597 scopus 로고    scopus 로고
    • Studies on the antiatherosclerotic effects of chitosan ester
    • Ding, H., Zhu, Q., Xu, L., Wu, B., Li, Y., Lv, Z., Studies on the antiatherosclerotic effects of chitosan ester. Chin J Mar Drugs 20:1 (2001), 12–16.
    • (2001) Chin J Mar Drugs , vol.20 , Issue.1 , pp. 12-16
    • Ding, H.1    Zhu, Q.2    Xu, L.3    Wu, B.4    Li, Y.5    Lv, Z.6
  • 60
    • 85063352813 scopus 로고    scopus 로고
    • Study on the antioxidant effect of chitin derivative (916) in vitro
    • Hu, J., Geng, M., Yu, G., Li, Y., Xu, J., Study on the antioxidant effect of chitin derivative (916) in vitro. Chin J Mar Drugs 20:1 (2001), 25–27.
    • (2001) Chin J Mar Drugs , vol.20 , Issue.1 , pp. 25-27
    • Hu, J.1    Geng, M.2    Yu, G.3    Li, Y.4    Xu, J.5
  • 61
    • 0001109070 scopus 로고    scopus 로고
    • Prophylactic effects of chitin derivative “916” on atherogenesis in hypercholesterolemic rabbits
    • Hu, J., Geng, M., Chen, K., Ran, Z., Xu, J., Guan, H., Prophylactic effects of chitin derivative “916” on atherogenesis in hypercholesterolemic rabbits. Chin J Mar Drugs 19:3 (2000), 18–21.
    • (2000) Chin J Mar Drugs , vol.19 , Issue.3 , pp. 18-21
    • Hu, J.1    Geng, M.2    Chen, K.3    Ran, Z.4    Xu, J.5    Guan, H.6
  • 62
    • 0036961162 scopus 로고    scopus 로고
    • Polysaccharide sulfate 916 inhibits neutrophil-endothelial adhesion
    • Ren, D., Geng, M., Du, G., Zhang, J., Polysaccharide sulfate 916 inhibits neutrophil-endothelial adhesion. Chin Med J (Engl) 115:12 (2002), 1855–1858.
    • (2002) Chin Med J (Engl) , vol.115 , Issue.12 , pp. 1855-1858
    • Ren, D.1    Geng, M.2    Du, G.3    Zhang, J.4
  • 64
    • 85063356318 scopus 로고    scopus 로고
    • Using HPCE Method to Study Marine Sulfated Polysaccharide 916 and Human Serum Albumin Interactions
    • Ocean University of China Qingdao
    • Yang, Z., Using HPCE Method to Study Marine Sulfated Polysaccharide 916 and Human Serum Albumin Interactions. 2010, Ocean University of China, Qingdao.
    • (2010)
    • Yang, Z.1
  • 65
    • 85063350026 scopus 로고    scopus 로고
    • The Influence of Marine Sulfated Polysaccharide 916 on Exterior and Interior Pharmacokinetics of Lovastatin in Rats
    • Ocean University of China Qingdao
    • Sun, W., The Influence of Marine Sulfated Polysaccharide 916 on Exterior and Interior Pharmacokinetics of Lovastatin in Rats. 2008, Ocean University of China, Qingdao.
    • (2008)
    • Sun, W.1
  • 66
    • 85063330792 scopus 로고    scopus 로고
    • The Influence of Marine Sulfated Polysaccharide 916 on the Pharmacokinetics of Pravastatin in Rats
    • Ocean University of China Qingdao
    • Zhang, R., The Influence of Marine Sulfated Polysaccharide 916 on the Pharmacokinetics of Pravastatin in Rats. 2008, Ocean University of China, Qingdao.
    • (2008)
    • Zhang, R.1
  • 67
    • 85027284116 scopus 로고    scopus 로고
    • Pharmacokinetics, tissue distribution and excretion study of fluorescein-labeled PS916 in rats
    • Yu, M., Wang, Y., Ma, F., Yu, W., Jiang, T., LV, Z., Pharmacokinetics, tissue distribution and excretion study of fluorescein-labeled PS916 in rats. Curr Pharm Biotechnol 18:5 (2017), 391–399.
    • (2017) Curr Pharm Biotechnol , vol.18 , Issue.5 , pp. 391-399
    • Yu, M.1    Wang, Y.2    Ma, F.3    Yu, W.4    Jiang, T.5    LV, Z.6
  • 68
    • 84876979065 scopus 로고    scopus 로고
    • An HPLC method for microanalysis and pharmacokinetics of marine sulfated polysaccharide PSS-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles in rat plasma
    • Li, P.L., Li, C.X., Xue, Y.T., et al. An HPLC method for microanalysis and pharmacokinetics of marine sulfated polysaccharide PSS-loaded poly lactic-co-glycolic acid (PLGA) nanoparticles in rat plasma. Mar Drugs 11:4 (2013), 1113–1125.
    • (2013) Mar Drugs , vol.11 , Issue.4 , pp. 1113-1125
    • Li, P.L.1    Li, C.X.2    Xue, Y.T.3
  • 69
    • 84893157571 scopus 로고    scopus 로고
    • Progress of marine drug propylene glycol alginate sodium sulfate (PSS) and inspiration
    • Li, C., Sun, Y., Guan, H., Progress of marine drug propylene glycol alginate sodium sulfate (PSS) and inspiration. Chin Bull Life Sci 24:9 (2012), 1019–1025.
    • (2012) Chin Bull Life Sci , vol.24 , Issue.9 , pp. 1019-1025
    • Li, C.1    Sun, Y.2    Guan, H.3
  • 70
    • 84958960139 scopus 로고    scopus 로고
    • Dynamic observation of hemorrheology in patients with cerebral infarction treated by PSS
    • Chen, J., Dynamic observation of hemorrheology in patients with cerebral infarction treated by PSS. Chin Pract Med 7:14 (2012), 159–160.
    • (2012) Chin Pract Med , vol.7 , Issue.14 , pp. 159-160
    • Chen, J.1
  • 71
    • 34347355392 scopus 로고    scopus 로고
    • The influence of molecular mass of sulfated propylene glycol ester of low-molecular-weight alginate on anticoagulant activities
    • Lin, C., Guan, H., Li, H., Yu, G., Gu, C., Li, G., The influence of molecular mass of sulfated propylene glycol ester of low-molecular-weight alginate on anticoagulant activities. Eur Polym J 43:7 (2007), 3009–3015.
    • (2007) Eur Polym J , vol.43 , Issue.7 , pp. 3009-3015
    • Lin, C.1    Guan, H.2    Li, H.3    Yu, G.4    Gu, C.5    Li, G.6
  • 72
    • 85063190628 scopus 로고    scopus 로고
    • Efficacy of polysaccharide sulfate for acute cerebral infarction and comparison of four items plasma biomoleculars in before and after treatment
    • Xu, J., Zhou, Q., Xu, C., et al. Efficacy of polysaccharide sulfate for acute cerebral infarction and comparison of four items plasma biomoleculars in before and after treatment. Chin J New Drugs Clin Remed 21:10 (2002), 591–594.
    • (2002) Chin J New Drugs Clin Remed , vol.21 , Issue.10 , pp. 591-594
    • Xu, J.1    Zhou, Q.2    Xu, C.3
  • 73
    • 84958965193 scopus 로고    scopus 로고
    • Clinical observation of 50 hyperlipidemia patients injected polysaccharide sulfate
    • Zhang, X., Wang, Y., Guo, A., Liu, Z., Zhang, B., Guo, Y., Clinical observation of 50 hyperlipidemia patients injected polysaccharide sulfate. Hebei Med 14:11 (2011), 1473–1477.
    • (2011) Hebei Med , vol.14 , Issue.11 , pp. 1473-1477
    • Zhang, X.1    Wang, Y.2    Guo, A.3    Liu, Z.4    Zhang, B.5    Guo, Y.6
  • 74
    • 85063345221 scopus 로고    scopus 로고
    • The effect of patients with diabetic nephropathy treated by polysaccharide sodium
    • Zhai, H., Duan, Y., Wang, Y., Zhang, Y., The effect of patients with diabetic nephropathy treated by polysaccharide sodium. J Pract Med Technol 14:19 (2007), 2535–2536.
    • (2007) J Pract Med Technol , vol.14 , Issue.19 , pp. 2535-2536
    • Zhai, H.1    Duan, Y.2    Wang, Y.3    Zhang, Y.4
  • 75
    • 85063221723 scopus 로고    scopus 로고
    • Neuroprotective role of PSS following cerebral ischemic reperfusion in rats
    • Liu, B., Zhang, Y., Zang, H., et al. Neuroprotective role of PSS following cerebral ischemic reperfusion in rats. J Clin Neurol 18:5 (2005), 363–366.
    • (2005) J Clin Neurol , vol.18 , Issue.5 , pp. 363-366
    • Liu, B.1    Zhang, Y.2    Zang, H.3
  • 76
    • 34547252247 scopus 로고    scopus 로고
    • Effect of polysaccharide sulfate on insulin-resistance in treatment of type 2 diabetes mellitus and hyperlipidemia
    • Zhang, C., Jiang, L., Liu, K., et al. Effect of polysaccharide sulfate on insulin-resistance in treatment of type 2 diabetes mellitus and hyperlipidemia. Chin J Clin Pharmacol 12:1 (2003), 24–26.
    • (2003) Chin J Clin Pharmacol , vol.12 , Issue.1 , pp. 24-26
    • Zhang, C.1    Jiang, L.2    Liu, K.3
  • 77
    • 85063320036 scopus 로고    scopus 로고
    • Effect of PSS on high sensitivity C reactive protein in patients with acute cerebral infarction
    • San, X., Lin, S., Gao, P., Effect of PSS on high sensitivity C reactive protein in patients with acute cerebral infarction. Mod J Integr Tradit Chin West Med 19:32 (2010), 4729–4730.
    • (2010) Mod J Integr Tradit Chin West Med , vol.19 , Issue.32 , pp. 4729-4730
    • San, X.1    Lin, S.2    Gao, P.3
  • 78
    • 85016720651 scopus 로고    scopus 로고
    • The polysaccharide sulfate enhance neovascularization of aeidie fibroblast growth factor
    • Zhang, J., Zhang, A., Chen, S., et al. The polysaccharide sulfate enhance neovascularization of aeidie fibroblast growth factor. Chin J Cardiovasc Med 2:1 (1997), 12–14.
    • (1997) Chin J Cardiovasc Med , vol.2 , Issue.1 , pp. 12-14
    • Zhang, J.1    Zhang, A.2    Chen, S.3
  • 79
    • 84904136950 scopus 로고    scopus 로고
    • Preparation, characterization and pharmacokinetics of fluorescence labeled propylene glycol alginate sodium sulfate
    • Li, P., Li, C., Xue, Y., et al. Preparation, characterization and pharmacokinetics of fluorescence labeled propylene glycol alginate sodium sulfate. J Ocean Univ China 13:4 (2014), 683–690.
    • (2014) J Ocean Univ China , vol.13 , Issue.4 , pp. 683-690
    • Li, P.1    Li, C.2    Xue, Y.3
  • 80
    • 85063352124 scopus 로고    scopus 로고
    • Effect of ASA combined with PSS on the prevention of ischemic cardio-cerebrovascular diseases among high-risk population
    • Xu, B., Xu, Q., Yan, Y., et al. Effect of ASA combined with PSS on the prevention of ischemic cardio-cerebrovascular diseases among high-risk population. Occup Health 23:3 (2007), 166–168.
    • (2007) Occup Health , vol.23 , Issue.3 , pp. 166-168
    • Xu, B.1    Xu, Q.2    Yan, Y.3
  • 81
    • 85063332195 scopus 로고    scopus 로고
    • Effect of aspirin combined with PSS on prevention of recurrent cerebral infarction
    • Bai, Z., Zhang, H., Ge, L., Han, H., Effect of aspirin combined with PSS on prevention of recurrent cerebral infarction. Shandong Med J 49:32 (2009), 100–101.
    • (2009) Shandong Med J , vol.49 , Issue.32 , pp. 100-101
    • Bai, Z.1    Zhang, H.2    Ge, L.3    Han, H.4
  • 82
    • 85063355076 scopus 로고    scopus 로고
    • Observation on therapeutic effect of sodium alginate diester combined with benzafibrate on dyslipidemia
    • Jin, M., Sui, X., Observation on therapeutic effect of sodium alginate diester combined with benzafibrate on dyslipidemia. Heilongjiang Med Pharm, 31(3), 2008, 91.
    • (2008) Heilongjiang Med Pharm , vol.31 , Issue.3 , pp. 91
    • Jin, M.1    Sui, X.2
  • 83
    • 85063320222 scopus 로고    scopus 로고
    • Clinical observation of bezafibrate combined with propylene glycol alginate sodium in the treatment of acute hyperlipidemic pancreatitis
    • Liang, Y., Clinical observation of bezafibrate combined with propylene glycol alginate sodium in the treatment of acute hyperlipidemic pancreatitis. Intern Med Chin 6:5 (2011), 430–433.
    • (2011) Intern Med Chin , vol.6 , Issue.5 , pp. 430-433
    • Liang, Y.1
  • 84
    • 85063204674 scopus 로고    scopus 로고
    • Effect of cinepazide maleate combined with alginic sodium diester on treatment of otogenic vertigo
    • Sun, J., Jiang, L., Effect of cinepazide maleate combined with alginic sodium diester on treatment of otogenic vertigo. Clin J Med Off 43:10 (2015), 1010–1012.
    • (2015) Clin J Med Off , vol.43 , Issue.10 , pp. 1010-1012
    • Sun, J.1    Jiang, L.2
  • 85
    • 85063331311 scopus 로고    scopus 로고
    • Advances in the study of the pharmacological and clinical application of PGMS
    • Zhang, P., Xia, Q., Zhao, X., Advances in the study of the pharmacological and clinical application of PGMS. Jiangsu Pharmacol Clin Res 9:1 (2001), 38–40.
    • (2001) Jiangsu Pharmacol Clin Res , vol.9 , Issue.1 , pp. 38-40
    • Zhang, P.1    Xia, Q.2    Zhao, X.3
  • 86
    • 0041667057 scopus 로고
    • The study of antithrombotic effect and mechanism of propylene glycol mannate sufate
    • Jiang, G., Yuan, W., Zhang, S., The study of antithrombotic effect and mechanism of propylene glycol mannate sufate. Chin J Mar Drugs 1 (1994), 6–13.
    • (1994) Chin J Mar Drugs , vol.1 , pp. 6-13
    • Jiang, G.1    Yuan, W.2    Zhang, S.3
  • 87
    • 0031292166 scopus 로고    scopus 로고
    • Effects of PGMS on the functions of human platelets and endothelial cells
    • Weng, J., Zhu, X., Lin, Y., Wang, Z., Effects of PGMS on the functions of human platelets and endothelial cells. Acta Acad Med Sin 19:6 (1997), 414–418.
    • (1997) Acta Acad Med Sin , vol.19 , Issue.6 , pp. 414-418
    • Weng, J.1    Zhu, X.2    Lin, Y.3    Wang, Z.4
  • 88
    • 85063339242 scopus 로고    scopus 로고
    • Protective effect of PGMS on acute cerebral ischemia reperfusion injury in rats
    • Zhang, M., Lin, H., Zhang, X., Wei, X., Protective effect of PGMS on acute cerebral ischemia reperfusion injury in rats. China Foreign Med Treat 22 (2011), 30–31.
    • (2011) China Foreign Med Treat , vol.22 , pp. 30-31
    • Zhang, M.1    Lin, H.2    Zhang, X.3    Wei, X.4
  • 89
    • 84979955384 scopus 로고    scopus 로고
    • Effects of propylene glycol mannite sulfate on the expression of tumor necrosis factor-α and interleukin-1β in the rat with diabetic retinopathy
    • Zhou, W., Wang, H., Du, X., Dong, W., Effects of propylene glycol mannite sulfate on the expression of tumor necrosis factor-α and interleukin-1β in the rat with diabetic retinopathy. Int J Ophthalmol 16:8 (2016), 1444–1448.
    • (2016) Int J Ophthalmol , vol.16 , Issue.8 , pp. 1444-1448
    • Zhou, W.1    Wang, H.2    Du, X.3    Dong, W.4
  • 90
    • 85063317201 scopus 로고
    • Studies on the in Vivo pharmackinetics of propylene glycol mannurate sulfate in mice
    • Sheng, S., Li, Y., Ma, J., Yuan, W., Studies on the in Vivo pharmackinetics of propylene glycol mannurate sulfate in mice. Chin J Mar Drugs 14:2 (1995), 15–17.
    • (1995) Chin J Mar Drugs , vol.14 , Issue.2 , pp. 15-17
    • Sheng, S.1    Li, Y.2    Ma, J.3    Yuan, W.4
  • 91
    • 85063319903 scopus 로고    scopus 로고
    • Effect of PGMSr on blood lipid level and hemorheology in hyperlipidemia
    • Gong, H., Liu, X., Effect of PGMSr on blood lipid level and hemorheology in hyperlipidemia. Clin Focus 15:11 (2000), 513–514.
    • (2000) Clin Focus , vol.15 , Issue.11 , pp. 513-514
    • Gong, H.1    Liu, X.2
  • 92
    • 85063334867 scopus 로고    scopus 로고
    • Effects of mannose ester on blood lipids, serum oxidized low density lipoprotein, C-reactive protein in patients with coronary heart disease complicated with hyperlipidemia
    • Tan, L., Wang, C., Zhang, W., Effects of mannose ester on blood lipids, serum oxidized low density lipoprotein, C-reactive protein in patients with coronary heart disease complicated with hyperlipidemia. Chin J Mar Drugs 27:3 (2008), 28–30.
    • (2008) Chin J Mar Drugs , vol.27 , Issue.3 , pp. 28-30
    • Tan, L.1    Wang, C.2    Zhang, W.3
  • 93
    • 85063316363 scopus 로고    scopus 로고
    • An exploration on the mechanism of antioxidant effect of PGMS in patients with chronic cor-pul-monale
    • Chen, Z., Zhao, X., Yang, S., Liu, Q., Guan, H., Li, G., An exploration on the mechanism of antioxidant effect of PGMS in patients with chronic cor-pul-monale. Chin J Mar Drugs 1 (1997), 50–52.
    • (1997) Chin J Mar Drugs , vol.1 , pp. 50-52
    • Chen, Z.1    Zhao, X.2    Yang, S.3    Liu, Q.4    Guan, H.5    Li, G.6
  • 94
    • 34247206544 scopus 로고    scopus 로고
    • Preparation of low-molecular-weight polyguluronate sulfate and its anticoagulant and anti-inflammatory activities
    • Zhao, X., Yu, G., Guan, H., Yue, N., Zhang, Z., Li, H., Preparation of low-molecular-weight polyguluronate sulfate and its anticoagulant and anti-inflammatory activities. Carbohydr Polym 69:2 (2007), 272–279.
    • (2007) Carbohydr Polym , vol.69 , Issue.2 , pp. 272-279
    • Zhao, X.1    Yu, G.2    Guan, H.3    Yue, N.4    Zhang, Z.5    Li, H.6
  • 95
    • 36348962444 scopus 로고    scopus 로고
    • Effects of low-molecular-weight polyguluronate sulfate on experimental urolithiasis in rats
    • Zhao, X., Yu, G., Yue, N., Guan, H., Effects of low-molecular-weight polyguluronate sulfate on experimental urolithiasis in rats. Urol Res 35:6 (Dec 2007), 301–306.
    • (2007) Urol Res , vol.35 , Issue.6 , pp. 301-306
    • Zhao, X.1    Yu, G.2    Yue, N.3    Guan, H.4
  • 96
    • 0026766970 scopus 로고
    • The effect of two new semi-synthetic glycosaminoglycans (G871, G872) on the zeta potential of calcium oxalate crystals and on growth and agglomeration
    • Cao, L.C., Boevé, E.R., Schröder, F.H., Robertson, W.G., Ketelaars, G.A.M., Bruijn, W.C.D., The effect of two new semi-synthetic glycosaminoglycans (G871, G872) on the zeta potential of calcium oxalate crystals and on growth and agglomeration. J Urol 147:6 (1992), 1643–1646.
    • (1992) J Urol , vol.147 , Issue.6 , pp. 1643-1646
    • Cao, L.C.1    Boevé, E.R.2    Schröder, F.H.3    Robertson, W.G.4    Ketelaars, G.A.M.5    Bruijn, W.C.D.6
  • 97
    • 0029656030 scopus 로고    scopus 로고
    • Effect of two new polysaccharides on growth, agglomeration and zeta potential of calcium phosphate crystals
    • Boevé, E.R., Schröder, F.H., Cao, L.C., Deng, G., Bruijn, W.C.D., Effect of two new polysaccharides on growth, agglomeration and zeta potential of calcium phosphate crystals. J Urol 155:1 (1996), 368–373.
    • (1996) J Urol , vol.155 , Issue.1 , pp. 368-373
    • Boevé, E.R.1    Schröder, F.H.2    Cao, L.C.3    Deng, G.4    Bruijn, W.C.D.5
  • 99
    • 84958257959 scopus 로고    scopus 로고
    • Anti-HBV activity and mechanism of marine-derived polyguluronate sulfate (PGS) in vitro
    • Wu, L., Wang, W., Zhang, X., Zhao, X., Yu, G., Anti-HBV activity and mechanism of marine-derived polyguluronate sulfate (PGS) in vitro. Carbohydr Polym 143 (Jun 5 2016), 139–148.
    • (2016) Carbohydr Polym , vol.143 , pp. 139-148
    • Wu, L.1    Wang, W.2    Zhang, X.3    Zhao, X.4    Yu, G.5
  • 100
    • 85063330984 scopus 로고    scopus 로고
    • A method for preparation PGS and its application. n.d. CN. Patent. 200310105718.9.2004-11-10.
    • Guan H, Li G, Zhao X. A method for preparation PGS and its application. n.d. CN. Patent. 200310105718.9.2004-11-10.
    • Guan, H.1    Li, G.2    Zhao, X.3
  • 101
    • 27844450565 scopus 로고    scopus 로고
    • Sulfated polymannuroguluronate (SPMG), a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, inhibits T cell apoptosis via combating oxidative damage of mitochondria
    • Miao, B., Li, J., Fu, X., Gan, L., Xin, X., Geng, M., Sulfated polymannuroguluronate (SPMG), a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, inhibits T cell apoptosis via combating oxidative damage of mitochondria. Mol Pharmacol 68:6 (2005), 1716–1727.
    • (2005) Mol Pharmacol , vol.68 , Issue.6 , pp. 1716-1727
    • Miao, B.1    Li, J.2    Fu, X.3    Gan, L.4    Xin, X.5    Geng, M.6
  • 102
    • 0043207423 scopus 로고    scopus 로고
    • The potential molecular targets of marine sulfated polymannuroguluronate interfering with HIV-1 entryInteraction between SPMG and HIV-1 rgp120 and CD4 molecule
    • Geng, M., Li, F., Xin, X., Li, J., Yan, Z., Guan, H., The potential molecular targets of marine sulfated polymannuroguluronate interfering with HIV-1 entryInteraction between SPMG and HIV-1 rgp120 and CD4 molecule. Antiviral Res 59:2 (2003), 127–135.
    • (2003) Antiviral Res , vol.59 , Issue.2 , pp. 127-135
    • Geng, M.1    Li, F.2    Xin, X.3    Li, J.4    Yan, Z.5    Guan, H.6
  • 103
    • 0041961155 scopus 로고    scopus 로고
    • Study on the mechanism of inhibitory action of 911 on replication of HIV-1 in vitro
    • Xin, X., Geng, M., Guan, H., Li, Z., Study on the mechanism of inhibitory action of 911 on replication of HIV-1 in vitro. Chin J Mar Drugs 19:4 (2000), 15–18.
    • (2000) Chin J Mar Drugs , vol.19 , Issue.4 , pp. 15-18
    • Xin, X.1    Geng, M.2    Guan, H.3    Li, Z.4
  • 104
    • 14644400703 scopus 로고    scopus 로고
    • Studies of the anti-AIDS effects of marine polysaccharide drug 911 and its related mechanisms of action
    • Xin, X., Ding, H., Geng, M., Liang, P., Li, Y., Guan, H., Studies of the anti-AIDS effects of marine polysaccharide drug 911 and its related mechanisms of action. Chin J Mar Drugs 19:6 (2000), 4–8.
    • (2000) Chin J Mar Drugs , vol.19 , Issue.6 , pp. 4-8
    • Xin, X.1    Ding, H.2    Geng, M.3    Liang, P.4    Li, Y.5    Guan, H.6
  • 105
    • 24044513314 scopus 로고    scopus 로고
    • Multiple and multivalent interactions of novel anti-AIDS drug candidates, sulfated polymannuronate (SPMG)-derived oligosaccharides, with gp120 and their anti-HIV activities
    • Liu, H., Geng, M., Xin, X., et al. Multiple and multivalent interactions of novel anti-AIDS drug candidates, sulfated polymannuronate (SPMG)-derived oligosaccharides, with gp120 and their anti-HIV activities. Glycobiology 15:5 (May 2005), 501–510.
    • (2005) Glycobiology , vol.15 , Issue.5 , pp. 501-510
    • Liu, H.1    Geng, M.2    Xin, X.3
  • 106
    • 34548818511 scopus 로고    scopus 로고
    • Sulfated polymannuroguluronate, a novel anti-AIDS drug candidate, inhibits HIV-1 Tat-induced angiogenesis in Kaposi's sarcoma cells
    • Lu, C., Li, J., Sun, Y., et al. Sulfated polymannuroguluronate, a novel anti-AIDS drug candidate, inhibits HIV-1 Tat-induced angiogenesis in Kaposi's sarcoma cells. Biochem Pharmacol 74:9 (2007), 1330–1339.
    • (2007) Biochem Pharmacol , vol.74 , Issue.9 , pp. 1330-1339
    • Lu, C.1    Li, J.2    Sun, Y.3
  • 107
    • 41149123450 scopus 로고    scopus 로고
    • Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, decreased vulnerability of PC12 cells to human immunodeficiency virus Tat protein through attenuating calcium overload
    • Hui, B., Li, J., Geng, M., Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, decreased vulnerability of PC12 cells to human immunodeficiency virus Tat protein through attenuating calcium overload. J Neurosci Res 86:5 (Apr 2008), 1169–1177.
    • (2008) J Neurosci Res , vol.86 , Issue.5 , pp. 1169-1177
    • Hui, B.1    Li, J.2    Geng, M.3
  • 108
    • 79959721660 scopus 로고    scopus 로고
    • Sulfated polymannuroguluronate inhibits tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad
    • Wu, Y., Ai, J., Zhao, J., et al. Sulfated polymannuroguluronate inhibits tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad. Acta Pharmacol Sin 32:5 (May 2011), 647–654.
    • (2011) Acta Pharmacol Sin , vol.32 , Issue.5 , pp. 647-654
    • Wu, Y.1    Ai, J.2    Zhao, J.3
  • 109
    • 0036986866 scopus 로고    scopus 로고
    • Research status and prospect of seaweed sulfated polysaccharide in anti HIV activity
    • Zhong, J., Xie, M., Gan, C., Research status and prospect of seaweed sulfated polysaccharide in anti HIV activity. Chin J Pharm 37:12 (2002), 884–887.
    • (2002) Chin J Pharm , vol.37 , Issue.12 , pp. 884-887
    • Zhong, J.1    Xie, M.2    Gan, C.3
  • 110
    • 84871767895 scopus 로고    scopus 로고
    • Study on “911” anti-HBV effect in HepG2.2.15 cells culture
    • Jiang, F., Xu, X., Li, L., Yuan, W., Study on “911” anti-HBV effect in HepG2.2.15 cells culture. Mod Prev Med 30:4 (2003), 517–518.
    • (2003) Mod Prev Med , vol.30 , Issue.4 , pp. 517-518
    • Jiang, F.1    Xu, X.2    Li, L.3    Yuan, W.4
  • 111
    • 33645914138 scopus 로고    scopus 로고
    • Preparation and identification of a series of mannose glucuronic acid oligosaccharides
    • Liu, B., Wang, C., Zhang, H., et al. Preparation and identification of a series of mannose glucuronic acid oligosaccharides. Chem J Chin Univ 27:3 (2006), 485–487.
    • (2006) Chem J Chin Univ , vol.27 , Issue.3 , pp. 485-487
    • Liu, B.1    Wang, C.2    Zhang, H.3
  • 112
    • 31644449884 scopus 로고    scopus 로고
    • Effects of acidic oligose on differentially expressed genes in the mice model of Alzhemier’ s disease by microarray
    • Kong, L., Geng, M., Mou, L., Xin, X., Yang, N., Zuo, P., Effects of acidic oligose on differentially expressed genes in the mice model of Alzhemier’ s disease by microarray. Acta Pharm Sin 40:12 (2005), 1105–1109.
    • (2005) Acta Pharm Sin , vol.40 , Issue.12 , pp. 1105-1109
    • Kong, L.1    Geng, M.2    Mou, L.3    Xin, X.4    Yang, N.5    Zuo, P.6
  • 113
    • 85063346201 scopus 로고    scopus 로고
    • GV-971, a new drug against Alzheimer's disease
    • Geng, M., GV-971, a new drug against Alzheimer's disease. Chin J Pharmacol Toxicol 31:5 (2017), 459–460.
    • (2017) Chin J Pharmacol Toxicol , vol.31 , Issue.5 , pp. 459-460
    • Geng, M.1
  • 114
    • 85063343059 scopus 로고    scopus 로고
    • Establishment of Immunoassay for Clinical Pharmacokinetic Studies of Oligomannurarate(971), a Novel Anti-Alzheimer's Drug Candidate
    • Ocean University of China Qingdao
    • Liu, P., Establishment of Immunoassay for Clinical Pharmacokinetic Studies of Oligomannurarate(971), a Novel Anti-Alzheimer's Drug Candidate. 2009, Ocean University of China, Qingdao.
    • (2009)
    • Liu, P.1
  • 115
    • 80052832267 scopus 로고    scopus 로고
    • Insulin sensitizing effects of oligomannuronate-chromium (III) complexes in C2C12 skeletal muscle cells
    • Hao, C., Hao, J., Wang, W., et al. Insulin sensitizing effects of oligomannuronate-chromium (III) complexes in C2C12 skeletal muscle cells. PLoS One, 6(9), 2011, e24598.
    • (2011) PLoS One , vol.6 , Issue.9
    • Hao, C.1    Hao, J.2    Wang, W.3
  • 116
    • 85063337660 scopus 로고    scopus 로고
    • A marine oligosaccharide compounds with activity against type 2 diabetes. n.d. CN. Patent 200910177710.0.2010-2-17.
    • Zhao X, Yu G, Guan H, Li G, Hao C. A marine oligosaccharide compounds with activity against type 2 diabetes. n.d. CN. Patent 200910177710.0.2010-2-17.
    • Zhao, X.1    Yu, G.2    Guan, H.3    Li, G.4    Hao, C.5
  • 117
    • 85063323921 scopus 로고    scopus 로고
    • Studies on the Preparation and Anti-Type 2 Diabetes Mechanisms of Marine Oligosaccharide Derivatives
    • Ocean University of China Qingdao
    • Cui, H., Studies on the Preparation and Anti-Type 2 Diabetes Mechanisms of Marine Oligosaccharide Derivatives. 2011, Ocean University of China, Qingdao.
    • (2011)
    • Cui, H.1
  • 118
    • 84861101929 scopus 로고    scopus 로고
    • Microanalysis of oligosaccharide HS203 in beagle dog plasma by postcolumn fluorescence derivatization method
    • Sun, S., Zhao, X., Li, G., et al. Microanalysis of oligosaccharide HS203 in beagle dog plasma by postcolumn fluorescence derivatization method. Carbohydr Polym 89:2 (2012), 661–666.
    • (2012) Carbohydr Polym , vol.89 , Issue.2 , pp. 661-666
    • Sun, S.1    Zhao, X.2    Li, G.3
  • 119
    • 33845706310 scopus 로고    scopus 로고
    • Analysis of plasma proteins that bind to glycosaminoglycans
    • Saito, A., Munakata, H., Analysis of plasma proteins that bind to glycosaminoglycans. Biochim Biophys Acta 1770:2 (Feb 2007), 241–246.
    • (2007) Biochim Biophys Acta , vol.1770 , Issue.2 , pp. 241-246
    • Saito, A.1    Munakata, H.2
  • 121
    • 79957592466 scopus 로고    scopus 로고
    • A systems biology approach for the investigation of the heparin/heparan sulfate interactome
    • Ori, A., Wilkinson, M.C., Fernig, D.G., A systems biology approach for the investigation of the heparin/heparan sulfate interactome. J Biol Chem 286:22 (2011), 19892–19904.
    • (2011) J Biol Chem , vol.286 , Issue.22 , pp. 19892-19904
    • Ori, A.1    Wilkinson, M.C.2    Fernig, D.G.3
  • 122
    • 84901448041 scopus 로고    scopus 로고
    • Heparin-protein interactions: from affinity and kinetics to biological roles. Application to an interaction network regulating angiogenesis
    • Peysselon, F., Ricard-Blum, S., Heparin-protein interactions: from affinity and kinetics to biological roles. Application to an interaction network regulating angiogenesis. Matrix Biol 35 (Apr 2014), 73–81.
    • (2014) Matrix Biol , vol.35 , pp. 73-81
    • Peysselon, F.1    Ricard-Blum, S.2
  • 123
    • 77953684080 scopus 로고    scopus 로고
    • Proteins that bind sulfated glycosaminoglycans
    • A. Varki R.D. Cummings et al. (eds.) Cold Spring Harbor NY
    • Esko, J.D., HP, J., Linhardt, R.J., Proteins that bind sulfated glycosaminoglycans. Varki, A., Cummings, R.D., et al. (eds.) Essentials of Glycobiology, 2015, Cold Spring Harbor, NY, 493–502.
    • (2015) Essentials of Glycobiology , pp. 493-502
    • Esko, J.D.1    HP, J.2    Linhardt, R.J.3
  • 124
    • 77958189486 scopus 로고    scopus 로고
    • Glycosaminoglycan (GAG) biosynthesis and GAG-binding proteins
    • Zhang, L., Glycosaminoglycan (GAG) biosynthesis and GAG-binding proteins. Prog Mol Biol Transl Sci 93 (2010), 1–17.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 1-17
    • Zhang, L.1
  • 125
    • 43149107206 scopus 로고    scopus 로고
    • Survival of heparins, oral anticoagulants, and aspirin after the year 2010
    • Fareed, J., Hoppensteadt, D.A., Fareed, D., et al. Survival of heparins, oral anticoagulants, and aspirin after the year 2010. Semin Thromb Hemost 34:1 (Feb 2008), 58–73.
    • (2008) Semin Thromb Hemost , vol.34 , Issue.1 , pp. 58-73
    • Fareed, J.1    Hoppensteadt, D.A.2    Fareed, D.3
  • 126
    • 0034852346 scopus 로고    scopus 로고
    • Heparan sulfate: anchor for viral intruders?
    • Spillmann, D., Heparan sulfate: anchor for viral intruders?. Biochimie 83:8 (2001), 811–817.
    • (2001) Biochimie , vol.83 , Issue.8 , pp. 811-817
    • Spillmann, D.1
  • 127
    • 85063110424 scopus 로고    scopus 로고
    • The clinical use of fondaparinux: a synthetic heparin pentasaccharide
    • Zhang, Y., Zhang, M., Tan, L., Pan, L., Zhang, L., The clinical use of fondaparinux: a synthetic heparin pentasaccharide. Prog Mol Biol Transl Sci 163 (2019), 41–53.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 41-53
    • Zhang, Y.1    Zhang, M.2    Tan, L.3    Pan, L.4    Zhang, L.5
  • 128
    • 85063325378 scopus 로고    scopus 로고
    • Mushroom polysaccharide lentinan for treating different types of cancers: a review of 12 years clinical studies in China
    • Zhang, M., Zhang, Y., Zhang, L., Tian, Q., Mushroom polysaccharide lentinan for treating different types of cancers: a review of 12 years clinical studies in China. Prog Mol Biol Transl Sci 163 (2019), 297–328.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 297-328
    • Zhang, M.1    Zhang, Y.2    Zhang, L.3    Tian, Q.4
  • 129
    • 85063302708 scopus 로고    scopus 로고
    • Ganoderma sinense polysaccharide: an adjunctive drug used for cancer treatment
    • Zhang, Y., Jiang, Y., Zhang, M., Zhang, L., Ganoderma sinense polysaccharide: an adjunctive drug used for cancer treatment. Prog Mol Biol Transl Sci 163 (2019), 165–177.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 165-177
    • Zhang, Y.1    Jiang, Y.2    Zhang, M.3    Zhang, L.4
  • 130
    • 85063253201 scopus 로고    scopus 로고
    • Ganoderma lucidum polysaccharide used for treating physical frailty in China
    • Zeng, P., Chen, Y., Zhang, L., Xing, M., Ganoderma lucidum polysaccharide used for treating physical frailty in China. Prog Mol Biol Transl Sci 163 (2019), 179–219.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 179-219
    • Zeng, P.1    Chen, Y.2    Zhang, L.3    Xing, M.4
  • 131
    • 85063083932 scopus 로고    scopus 로고
    • An overview of fungal glycan-based therapeutics
    • Yang, D., Zhou, Z., Zhang, L., An overview of fungal glycan-based therapeutics. Prog Mol Biol Transl Sci 163 (2019), 135–163.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 135-163
    • Yang, D.1    Zhou, Z.2    Zhang, L.3
  • 132
    • 85063342394 scopus 로고    scopus 로고
    • Tremella polysaccharide: the molecular mechanisms of its drug action
    • Yang, D., Liu, Y., Zhang, L., Tremella polysaccharide: the molecular mechanisms of its drug action. Prog Mol Biol Transl Sci 163 (2019), 383–421.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 383-421
    • Yang, D.1    Liu, Y.2    Zhang, L.3
  • 133
    • 85063351151 scopus 로고    scopus 로고
    • Molecular basis for Poria cocos mushroom polysaccharide used as an antitumor drug in China
    • Li, X., Ma, L., Zhang, L., Molecular basis for Poria cocos mushroom polysaccharide used as an antitumor drug in China. Prog Mol Biol Transl Sci 163 (2019), 263–296.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 263-296
    • Li, X.1    Ma, L.2    Zhang, L.3
  • 134
    • 85063317109 scopus 로고    scopus 로고
    • The efficacy of Polyporus Umbellatus polysaccharide in treating hepatitis B in China
    • Guo, Z., Zang, Y., Zhang, L., The efficacy of Polyporus Umbellatus polysaccharide in treating hepatitis B in China. Prog Mol Biol Transl Sci 163 (2019), 329–360.
    • (2019) Prog Mol Biol Transl Sci , vol.163 , pp. 329-360
    • Guo, Z.1    Zang, Y.2    Zhang, L.3
  • 135
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans fine-tune mammalian physiology
    • Bishop, J.R., Schuksz, M., Esko, J.D., Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446:7139 (2007), 1030–1037.
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 136
    • 84945216719 scopus 로고    scopus 로고
    • Studies on Fluorescent Labeling and Pharmacokinetics of Marine Sulfated Polysaccharide PS916
    • Ocean University of China Qingdao
    • Lv, Z., Studies on Fluorescent Labeling and Pharmacokinetics of Marine Sulfated Polysaccharide PS916. 2008, Ocean University of China, Qingdao.
    • (2008)
    • Lv, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.