-
1
-
-
84855854046
-
Chronic kidney disease
-
Levey AS, Coresh J. Chronic kidney disease. Lancet 2012; 379: 165-80
-
(2012)
Lancet
, vol.379
, pp. 165-180
-
-
Levey, A.S.1
Coresh, J.2
-
2
-
-
34347334551
-
Chronic kidney disease management in the United Kingdom: NEOERICA project results
-
Stevens PE, O'Donoghue DJ, de Lusignan S et al. Chronic kidney disease management in the United Kingdom: NEOERICA project results. Kidney Int 2007; 72: 92-99
-
(2007)
Kidney Int
, vol.72
, pp. 92-99
-
-
Stevens, P.E.1
O'Donoghue, D.J.2
De Lusignan, S.3
-
3
-
-
84924044822
-
The future burden of CKD in the United States: A simulation model for the CDC CKD Initiative
-
Hoerger TJ, Simpson SA, Yarnoff BO et al. The future burden of CKD in the United States: a simulation model for the CDC CKD Initiative. Am J Kidney Dis 2015; 65: 403-411
-
(2015)
Am J Kidney Dis
, vol.65
, pp. 403-411
-
-
Hoerger, T.J.1
Simpson, S.A.2
Yarnoff, B.O.3
-
4
-
-
84880511470
-
Chronic kidney disease: Global dimension and perspectives
-
Jha V, Garcia-Garcia G, Iseki K et al. Chronic kidney disease: global dimension and perspectives. Lancet 2013; 382: 260-272
-
(2013)
Lancet
, vol.382
, pp. 260-272
-
-
Jha, V.1
Garcia-Garcia, G.2
Iseki, K.3
-
5
-
-
85062010702
-
-
US Renal Data System. USRDS. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
-
US Renal Data System. USRDS. 2014 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2014, 2
-
(2014)
2014 Annual Data Report: Atlas of End-Stage Renal Disease in the United States
, pp. 2
-
-
-
6
-
-
84868540565
-
Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: A meta-analysis
-
Fox CS, Matsushita K, Woodward M et al. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet 2012; 380: 1662-1673
-
(2012)
Lancet
, vol.380
, pp. 1662-1673
-
-
Fox, C.S.1
Matsushita, K.2
Woodward, M.3
-
7
-
-
84928897701
-
What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease?
-
Kent S, Schlackow I, Lozano-Kühne J et al. What is the impact of chronic kidney disease stage and cardiovascular disease on the annual cost of hospital care in moderate-to-severe kidney disease? BMC Nephrol 2015; 16: 65
-
(2015)
BMC Nephrol
, vol.16
, pp. 65
-
-
Kent, S.1
Schlackow, I.2
Lozano-Kühne, J.3
-
8
-
-
84868547745
-
Estimating the financial cost of chronic kidney disease to the NHS in England
-
Kerr M, Bray B, Medcalf J et al. Estimating the financial cost of chronic kidney disease to the NHS in England. Nephrol Dial Transplant 2012; 27(Suppl 3): iii73-iii80
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. iii73-iii80
-
-
Kerr, M.1
Bray, B.2
Medcalf, J.3
-
9
-
-
77953291706
-
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: A collaborative meta-analysis
-
Matsushita K, van der Velde M, Astor BC, et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010; 375: 2073-2081
-
(2010)
Lancet
, vol.375
, pp. 2073-2081
-
-
Matsushita, K.1
Van Der Velde, M.2
Astor, B.C.3
-
10
-
-
0035902622
-
Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data
-
Jafar TH, Schmid CH, Landa M, et al. Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data. Ann Intern Med 2001; 135: 73-87
-
(2001)
Ann Intern Med
, vol.135
, pp. 73-87
-
-
Jafar, T.H.1
Schmid, C.H.2
Landa, M.3
-
11
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
12
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
De Zeeuw, D.3
-
13
-
-
84887467090
-
Combined angiotensin inhibition for the treatment of diabetic nephropathy
-
Fried LF, Emanuele N, Zhang JH et al. Combined angiotensin inhibition for the treatment of diabetic nephropathy. N Engl J Med 2013; 369: 1892-1903
-
(2013)
N Engl J Med
, vol.369
, pp. 1892-1903
-
-
Fried, L.F.1
Emanuele, N.2
Zhang, J.H.3
-
14
-
-
85016474227
-
The effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: A meta-analysis of individual participant data from randomised controlled trials
-
Zoungas S, Arima H, Gerstein HC et al. The effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials. Lancet Diabetes Endocrinol 2017; 5: 431-437
-
(2017)
Lancet Diabetes Endocrinol
, vol.5
, pp. 431-437
-
-
Zoungas, S.1
Arima, H.2
Gerstein, H.C.3
-
15
-
-
85016479722
-
Tightening our understanding of intensive glycaemic control
-
Herrington WG, Preiss D. Tightening our understanding of intensive glycaemic control. Lancet Diabetes Endocrinol 2017; 5: 405-407
-
(2017)
Lancet Diabetes Endocrinol
, vol.5
, pp. 405-407
-
-
Herrington, W.G.1
Preiss, D.2
-
16
-
-
84892375403
-
Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study
-
de Boer IH. Kidney disease and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care 2014; 37: 24-30
-
(2014)
Diabetes Care
, vol.37
, pp. 24-30
-
-
De Boer, I.H.1
-
17
-
-
84907862963
-
Follow-up of blood-pressure lowering and glucose control in type 2 diabetes
-
Zoungas S, Chalmers J, Neal B et al. Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. N Engl J Med 2014; 371: 1392-1406
-
(2014)
N Engl J Med
, vol.371
, pp. 1392-1406
-
-
Zoungas, S.1
Chalmers, J.2
Neal, B.3
-
18
-
-
0028215329
-
The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of diet in renal Disease Study group
-
Klahr S, Levey AS, Beck GJ et al. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med 1994; 330: 877-884
-
(1994)
N Engl J Med
, vol.330
, pp. 877-884
-
-
Klahr, S.1
Levey, A.S.2
Beck, G.J.3
-
19
-
-
84881488953
-
Effects of intensive blood pressure lowering on the progression of chronic kidney disease: A systematic review and meta-analysis
-
Lv J, Ehteshami P, Sarnak MJ et al. Effects of intensive blood pressure lowering on the progression of chronic kidney disease: a systematic review and meta-analysis. CMAJ 2013; 185: 949-957
-
(2013)
CMAJ
, vol.185
, pp. 949-957
-
-
Lv, J.1
Ehteshami, P.2
Sarnak, M.J.3
-
20
-
-
0037145856
-
Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: Results from the AASK trial
-
Wright JT Jr, Bakris G, Greene T, et al. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA 2002; 288: 2421-2431
-
(2002)
JAMA
, vol.288
, pp. 2421-2431
-
-
Wright, J.T.1
Bakris, G.2
Greene, T.3
-
21
-
-
84960094179
-
Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis
-
Ettehad D, Emdin CA, Kiran A et al. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet 2016; 387: 957-967
-
(2016)
Lancet
, vol.387
, pp. 957-967
-
-
Ettehad, D.1
Emdin, C.A.2
Kiran, A.3
-
22
-
-
84979729781
-
How are the effects of reducing LDL cholesterol with a statin-based regime influenced by renal function? Meta-analysis of individual data from 28 randomised trials
-
Herrington W, Emberson J, Mihaylova B, et al. How are the effects of reducing LDL cholesterol with a statin-based regime influenced by renal function? Meta-analysis of individual data from 28 randomised trials. Lancet Diabetes Endocrinol 2016; 4: 829-839
-
(2016)
Lancet Diabetes Endocrinol
, vol.4
, pp. 829-839
-
-
Herrington, W.1
Emberson, J.2
Mihaylova, B.3
-
23
-
-
84888016838
-
KDIGO clinical practice guideline for lipid management in chronic kidney disease
-
Kidney Disease: Improving Global Outcomes (KDIGO) Lipid Guideline Development Work Group. KDIGO clinical practice guideline for lipid management in chronic kidney disease. Kidney Int Suppl 2013; 3: 263-26
-
(2013)
Kidney Int Suppl
, vol.3
, pp. 263-326
-
-
-
25
-
-
84867162439
-
Associations between kidney function and subclinical cardiac abnormalities in CKD
-
Park M, Hsu C-Y, Li Y et al. Associations between kidney function and subclinical cardiac abnormalities in CKD. J Am Soc Nephrol 2012; 23: 1725-1734
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1725-1734
-
-
Park, M.1
Hsu, C.-Y.2
Li, Y.3
-
26
-
-
0031727746
-
Long-term evolution of cardiomyopathy in dialysis patients
-
Foley RN, Parfrey PS, Kent GM et al. Long-term evolution of cardiomyopathy in dialysis patients. Kidney Int 1998; 54: 1720-1725
-
(1998)
Kidney Int
, vol.54
, pp. 1720-1725
-
-
Foley, R.N.1
Parfrey, P.S.2
Kent, G.M.3
-
27
-
-
0033053766
-
Left ventricular mass index increase in early renal disease: Impact of decline in hemoglobin
-
Levin A, Thompson CR, Ethier J et al. Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin. Am J Kidney Dis 1999; 34: 125-134
-
(1999)
Am J Kidney Dis
, vol.34
, pp. 125-134
-
-
Levin, A.1
Thompson, C.R.2
Ethier, J.3
-
28
-
-
84886914661
-
Blood pressure lowering and major cardiovascular events in people with and without chronic kidney disease: Meta-analysis of randomised controlled trials
-
Ninomiya T, Perkovic V, Turnbull F et al. Blood pressure lowering and major cardiovascular events in people with and without chronic kidney disease: meta-analysis of randomised controlled trials. BMJ 2013; 347: f5680
-
(2013)
BMJ
, vol.347
, pp. f5680
-
-
Ninomiya, T.1
Perkovic, V.2
Turnbull, F.3
-
29
-
-
85018306708
-
Heart failure
-
Metra M, Teerlink JR. Heart failure. Lancet 2017; 390: 1981-1995
-
(2017)
Lancet
, vol.390
, pp. 1981-1995
-
-
Metra, M.1
Teerlink, J.R.2
-
30
-
-
67349189212
-
Renal sodium-glucose transport: Role in diabetes mellitus and potential clinical implications
-
Bakris GL, Fonseca VA, Sharma K et al. Renal sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Kidney Int 2009; 75: 1272-1277
-
(2009)
Kidney Int
, vol.75
, pp. 1272-1277
-
-
Bakris, G.L.1
Fonseca, V.A.2
Sharma, K.3
-
31
-
-
85034766786
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
Neal B, Perkovic V, Mahaffey KW et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med 2017; 377: 644-657
-
(2017)
N Engl J Med
, vol.377
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
-
32
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
Zinman B, Wanner C, Lachin JM et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 2015; 373: 2117-2128
-
(2015)
N Engl J Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
-
33
-
-
84979895487
-
Empagliflozin and progression of kidney disease in type 2 diabetes
-
Wanner C, Inzucchi SE, Lachin JM et al. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med 2016; 375: 323-334
-
(2016)
N Engl J Med
, vol.375
, pp. 323-334
-
-
Wanner, C.1
Inzucchi, S.E.2
Lachin, J.M.3
-
34
-
-
84865479822
-
Why do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans?
-
Liu JJ, Lee T, DeFronzo RA. Why do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans? Diabetes 2012; 61: 2199-2204
-
(2012)
Diabetes
, vol.61
, pp. 2199-2204
-
-
Liu, J.J.1
Lee, T.2
DeFronzo, R.A.3
-
35
-
-
75749094398
-
Familial renal glucosuria and SGLT2: From a mendelian trait to a therapeutic target
-
Santer R, Calado J. Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target. Clin J Am Soc Nephrol 2010; 5: 133-141
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, pp. 133-141
-
-
Santer, R.1
Calado, J.2
-
36
-
-
85016626296
-
SGLT2 protein expression is increased in human diabetic nephropathy
-
Wang XX, Levi J, Luo Y et al. SGLT2 protein expression is increased in human diabetic nephropathy. J Biol Chem 2017; 292: 5335-5348
-
(2017)
J Biol Chem
, vol.292
, pp. 5335-5348
-
-
Wang, X.X.1
Levi, J.2
Luo, Y.3
-
37
-
-
85047818222
-
SGLT2 inhibition for the prevention and treatment of diabetic kidney disease: A review
-
Alicic RZ, Johnson EJ, Tuttle KR. SGLT2 inhibition for the prevention and treatment of diabetic kidney disease: a review. Am J Kidney Dis 2018; 72: 267-277
-
(2018)
Am J Kidney Dis
, vol.72
, pp. 267-277
-
-
Alicic, R.Z.1
Johnson, E.J.2
Tuttle, K.R.3
-
38
-
-
84996486377
-
Targeting renal glucose reabsorption to treat hyperglycaemia: The pleiotropic effects of SGLT2 inhibition
-
Vallon V, Thomson SC. Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition. Diabetologia 2017; 60: 215-225
-
(2017)
Diabetologia
, vol.60
, pp. 215-225
-
-
Vallon, V.1
Thomson, S.C.2
-
39
-
-
84891534541
-
Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans
-
Abdul-Ghani MA, DeFronzo RA, Norton L. Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans. Diabetes 2013; 62: 3324-3328
-
(2013)
Diabetes
, vol.62
, pp. 3324-3328
-
-
Abdul-Ghani, M.A.1
DeFronzo, R.A.2
Norton, L.3
-
40
-
-
85030993345
-
Effects of the selective sodium-glucose cotransporter 2 inhibitor empagliflozin on vascular function and central hemodynamics in patients with type 2 diabetes mellitus
-
Striepe K, Jumar A, Ott C et al. Effects of the selective sodium-glucose cotransporter 2 inhibitor empagliflozin on vascular function and central hemodynamics in patients with type 2 diabetes mellitus. Circulation 2017; 136: 1167-1169
-
(2017)
Circulation
, vol.136
, pp. 1167-1169
-
-
Striepe, K.1
Jumar, A.2
Ott, C.3
-
41
-
-
84980320178
-
Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: Cardiovascular and kidney effects, potential mechanisms, and clinical applications
-
Heerspink HJ, Perkins BA, Fitchett DH et al. Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications. Circulation 2016; 134: 752-772
-
(2016)
Circulation
, vol.134
, pp. 752-772
-
-
Heerspink, H.J.1
Perkins, B.A.2
Fitchett, D.H.3
-
42
-
-
85027965828
-
The potential role and rationale for treatment of heart failure with sodium-glucose co-transporter 2 inhibitors
-
Butler J, Hamo CE, Filippatos G et al. The potential role and rationale for treatment of heart failure with sodium-glucose co-transporter 2 inhibitors. Eur J Heart Fail 2017; 19: 1390-1400
-
(2017)
Eur J Heart Fail
, vol.19
, pp. 1390-1400
-
-
Butler, J.1
Hamo, C.E.2
Filippatos, G.3
-
43
-
-
85020448574
-
Glomerular hyperfiltration in diabetes: Mechanisms, clinical significance, and treatment
-
Tonneijck L, Muskiet MHA, Smits MM et al. Glomerular hyperfiltration in diabetes: mechanisms, clinical significance, and treatment. J Am Soc Nephrol 2017; 28: 1023-1039
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 1023-1039
-
-
Tonneijck, L.1
Muskiet, M.H.A.2
Smits, M.M.3
-
44
-
-
85021254729
-
Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: An exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial
-
Cherney DZI, Zinman B, Inzucchi SE et al. Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial. Lancet Diabetes Endocrinol 2017; 5: 610-621
-
(2017)
Lancet Diabetes Endocrinol
, vol.5
, pp. 610-621
-
-
Cherney, D.Z.I.1
Zinman, B.2
Inzucchi, S.E.3
-
45
-
-
85048935795
-
Canagliflozin and renal outcomes in type 2 diabetes: Results from the CANVAS Program randomised clinical trials
-
Perkovic V, de Zeeum D, Mahaffey KW et al. Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS Program randomised clinical trials. Lancet Diabetes Endocrinol 2018; 6: 691-704
-
(2018)
Lancet Diabetes Endocrinol
, vol.6
, pp. 691-704
-
-
Perkovic, V.1
De Zeeum, D.2
Mahaffey, K.W.3
-
46
-
-
0025763907
-
Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport
-
Lorenz JN, Weihprecht H, Schnermann J et al. Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport. Am J Physiol 1991; 260(4 Pt 2): F486-F493
-
(1991)
Am J Physiol
, vol.260
, Issue.4
, pp. F486-F493
-
-
Lorenz, J.N.1
Weihprecht, H.2
Schnermann, J.3
-
47
-
-
84896988257
-
The kidney in congestive heart failure: 'are natriuresis, sodium, and diuretics really the good, the bad and the ugly?
-
Verbrugge FH, Dupont M, Steels P et al. The kidney in congestive heart failure: 'are natriuresis, sodium, and diuretics really the good, the bad and the ugly?'. Eur J Heart Fail 2014; 16: 133-142
-
(2014)
Eur J Heart Fail
, vol.16
, pp. 133-142
-
-
Verbrugge, F.H.1
Dupont, M.2
Steels, P.3
-
48
-
-
84866359727
-
Glomerular hyperfiltration: A marker of early renal damage in pre-diabetes and pre-hypertension
-
Palatini P. Glomerular hyperfiltration: a marker of early renal damage in pre-diabetes and pre-hypertension. Nephrol Dial Transplant 2012; 27: 1708-1714
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 1708-1714
-
-
Palatini, P.1
-
49
-
-
84929439992
-
Association between obesity and glomerular hyperfiltration: The confounding effect of smoking and sodium and protein intakes
-
Ogna A, Forni Ogna V, Bochud M et al. Association between obesity and glomerular hyperfiltration: the confounding effect of smoking and sodium and protein intakes. Eur J Nutr 2016; 55: 1089-1097
-
(2016)
Eur J Nutr
, vol.55
, pp. 1089-1097
-
-
Ogna, A.1
Forni Ogna, V.2
Bochud, M.3
-
50
-
-
84860279587
-
Glomerular hyperfiltration: Definitions, mechanisms and clinical implications
-
Helal I, Fick-Brosnahan GM, Reed-Gitomer B et al. Glomerular hyperfiltration: definitions, mechanisms and clinical implications. Nat Rev Nephrol 2012; 8: 293-300
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 293-300
-
-
Helal, I.1
Fick-Brosnahan, G.M.2
Reed-Gitomer, B.3
-
51
-
-
0029902698
-
The hyperfiltration theory: A paradigm shift in nephrology
-
Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int 1996; 49: 1774-1777
-
(1996)
Kidney Int
, vol.49
, pp. 1774-1777
-
-
Brenner, B.M.1
Lawler, E.V.2
Mackenzie, H.S.3
-
52
-
-
84903271292
-
Evaluating the contribution of the cause of kidney disease to prognosis in CKD: Results from the Study of heart and renal protection (SHARP)
-
Haynes R, Staplin N, Emberson J et al. Evaluating the contribution of the cause of kidney disease to prognosis in CKD: results from the Study of Heart and Renal Protection (SHARP). Am J Kidney Dis 2014; 64: 40-48
-
(2014)
Am J Kidney Dis
, vol.64
, pp. 40-48
-
-
Haynes, R.1
Staplin, N.2
Emberson, J.3
-
53
-
-
85018324492
-
ACE and SGLT2 inhibitors: The future for non-diabetic and diabetic proteinuric renal disease
-
Perico N, Ruggenenti P, Remuzzi G. ACE and SGLT2 inhibitors: the future for non-diabetic and diabetic proteinuric renal disease. Curr Opin Pharmacol 2017; 33: 34-40
-
(2017)
Curr Opin Pharmacol
, vol.33
, pp. 34-40
-
-
Perico, N.1
Ruggenenti, P.2
Remuzzi, G.3
-
54
-
-
84964608804
-
Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes
-
Ferrannini E, Baldi S, Frascerra S et al. Shift to fatty substrate utilization in response to sodium-glucose cotransporter 2 inhibition in subjects without diabetes and patients with type 2 diabetes. Diabetes 2016; 65: 1190-1195
-
(2016)
Diabetes
, vol.65
, pp. 1190-1195
-
-
Ferrannini, E.1
Baldi, S.2
Frascerra, S.3
-
55
-
-
85021083050
-
Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes
-
Al-Jobori H, Daniele G, Cersosimo E et al. Empagliflozin and kinetics of renal glucose transport in healthy individuals and individuals with type 2 diabetes. Diabetes 2017; 66: 1999-2006
-
(2017)
Diabetes
, vol.66
, pp. 1999-2006
-
-
Al-Jobori, H.1
Daniele, G.2
Cersosimo, E.3
-
56
-
-
84897447957
-
Canagliflozin: Effects in overweight and obese subjects without diabetes mellitus
-
Bays HE, Weinstein R, Law G et al. Canagliflozin: effects in overweight and obese subjects without diabetes mellitus. Obesity (Silver Spring) 2014; 22: 1042-1049
-
(2014)
Obesity (Silver Spring)
, vol.22
, pp. 1042-1049
-
-
Bays, H.E.1
Weinstein, R.2
Law, G.3
-
57
-
-
84960433486
-
SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: A systematic review and network meta-analysis
-
Shyangdan DS, Uthman OA, Waugh N. SGLT-2 receptor inhibitors for treating patients with type 2 diabetes mellitus: a systematic review and network meta-analysis. BMJ Open 2016; 6: e009417
-
(2016)
BMJ Open
, vol.6
-
-
Shyangdan, D.S.1
Uthman, O.A.2
Waugh, N.3
-
58
-
-
84882251091
-
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic review and meta-analysis
-
Vasilakou D, Karagiannis T, Athanasiadou E et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med 2013; 159: 262-274
-
(2013)
Ann Intern Med
, vol.159
, pp. 262-274
-
-
Vasilakou, D.1
Karagiannis, T.2
Athanasiadou, E.3
-
59
-
-
77956921439
-
Dapagliflozin mono-therapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: A randomized, double-blind, placebo-controlled, phase 3 trial
-
Ferrannini E, Ramos SJ, Salsali A et al. Dapagliflozin mono-therapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial. Diabetes Care 2010; 33: 2217-2224
-
(2010)
Diabetes Care
, vol.33
, pp. 2217-2224
-
-
Ferrannini, E.1
Ramos, S.J.2
Salsali, A.3
-
60
-
-
84885954870
-
Empagliflozin monother-apy with sitagliptin as an active comparator in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled, phase 3 trial
-
Roden M, Weng J, Eilbracht J et al. Empagliflozin monother-apy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol 2013; 1: 208-219
-
(2013)
Lancet Diabetes Endocrinol
, vol.1
, pp. 208-219
-
-
Roden, M.1
Weng, J.2
Eilbracht, J.3
-
61
-
-
85021694438
-
Differential effects of dapagliflozin on cardiovascular risk factors at varying degrees of renal function
-
Petrykiv S, Sjostrom CD, Greasley PJ et al. Differential effects of dapagliflozin on cardiovascular risk factors at varying degrees of renal function. Clin J Am Soc Nephrol 2017; 12: 751-759
-
(2017)
Clin J Am Soc Nephrol
, vol.12
, pp. 751-759
-
-
Petrykiv, S.1
Sjostrom, C.D.2
Greasley, P.J.3
-
62
-
-
85028413629
-
Pooled analysis of phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozin
-
Cherney DZI, Cooper ME, Tikkanen I et al. Pooled analysis of phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozin. Kidney Int 2018; 93: 231-244
-
(2018)
Kidney Int
, vol.93
, pp. 231-244
-
-
Cherney, D.Z.I.1
Cooper, M.E.2
Tikkanen, I.3
-
63
-
-
79956331954
-
Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects
-
Sha S, Devineni D, Ghosh A et al. Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects. Diabetes Obes Metab 2011; 13: 669-672
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 669-672
-
-
Sha, S.1
Devineni, D.2
Ghosh, A.3
-
64
-
-
84880320337
-
Pharmacokinetics and pharmacodynamics of canagliflozin, a sodium glucose cotransporter 2 inhibitor, in subjects with type 2 diabetes mellitus
-
Devineni D, Curtin CR, Polidori D et al. Pharmacokinetics and pharmacodynamics of canagliflozin, a sodium glucose cotransporter 2 inhibitor, in subjects with type 2 diabetes mellitus. J Clin Pharmacol 2013; 53: 601-610
-
(2013)
J Clin Pharmacol
, vol.53
, pp. 601-610
-
-
Devineni, D.1
Curtin, C.R.2
Polidori, D.3
-
66
-
-
84898854471
-
Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis
-
Baker WL, Smyth LR, Riche DM et al. Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis. J Am Soc Hypertens 2014; 8: 262-275.e9
-
(2014)
J Am Soc Hypertens
, vol.8
, pp. 262e9-275e9
-
-
Baker, W.L.1
Smyth, L.R.2
Riche, D.M.3
-
67
-
-
84908332537
-
Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: A 104-week randomised, active-controlled, double-blind, phase 3 trial
-
Ridderstråle M, Andersen KR, Zeller C et al. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol 2014; 2: 691-700
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 691-700
-
-
Ridderstråle, M.1
Andersen, K.R.2
Zeller, C.3
-
68
-
-
84951906012
-
Energy balance after sodium-glucose cotransporter 2 inhibition
-
Ferrannini G, Hach T, Crowe S et al. Energy balance after sodium-glucose cotransporter 2 inhibition. Diabetes Care 2015; 38: 1730-1735
-
(2015)
Diabetes Care
, vol.38
, pp. 1730-1735
-
-
Ferrannini, G.1
Hach, T.2
Crowe, S.3
-
69
-
-
84897394040
-
Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control
-
Kohan DE, Fioretto P, Tang W et al. Long-term study of patients with type 2 diabetes and moderate renal impairment shows that dapagliflozin reduces weight and blood pressure but does not improve glycemic control. Kidney Int 2014; 85: 962-971
-
(2014)
Kidney Int
, vol.85
, pp. 962-971
-
-
Kohan, D.E.1
Fioretto, P.2
Tang, W.3
-
70
-
-
85034093732
-
Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis
-
Hallow KM, Helmlinger G, Greasley PJ et al. Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis. Diabetes Obes Metab 2018; 20: 479-487
-
(2018)
Diabetes Obes Metab
, vol.20
, pp. 479-487
-
-
Hallow, K.M.1
Helmlinger, G.2
Greasley, P.J.3
-
71
-
-
84994853573
-
Impact of empagliflozin on blood pressure in patients with type 2 diabetes mellitus and hypertension by background antihypertensive medication
-
Mancia G, Cannon CP, Tikkanen I et al. Impact of empagliflozin on blood pressure in patients with type 2 diabetes mellitus and hypertension by background antihypertensive medication. Hypertension 2016; 68: 1355-1364
-
(2016)
Hypertension
, vol.68
, pp. 1355-1364
-
-
Mancia, G.1
Cannon, C.P.2
Tikkanen, I.3
-
72
-
-
85021849793
-
Canagliflozin slows progression of renal function decline independently of glycemic effects
-
Heerspink HJ, Desai M, Jardine M et al. Canagliflozin slows progression of renal function decline independently of glycemic effects. J Am Soc Nephrol 2017; 28: 368-375
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 368-375
-
-
Heerspink, H.J.1
Desai, M.2
Jardine, M.3
-
73
-
-
85062021440
-
Canagliflozin and renal outcomes in patients with chronic kidney disease
-
Austin, Texas. 13 April 2018, date last accessed
-
Neuen BL, Ohkuma T, Neal B, et al. Canagliflozin and Renal Outcomes in Patients with Chronic Kidney Disease. Poster at the National Kidney Federation Spring Clinical Meetings - April 10-14 2018, Austin, Texas. http://jgl_nkf2018.scientificpresenta tions.org/Neuen_JGL63181.pdf (13 April 2018, date last accessed)
-
Poster at the National Kidney Federation Spring Clinical Meetings - April 10-14 2018
-
-
Neuen, B.L.1
Ohkuma, T.2
Neal, B.3
-
75
-
-
85038113623
-
The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study rationale, design, and baseline characteristics
-
Jardine MJ, Mahaffey KW, Neal B et al. The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study rationale, design, and baseline characteristics. Am J Nephrol 2017; 46: 462-472
-
(2017)
Am J Nephrol
, vol.46
, pp. 462-472
-
-
Jardine, M.J.1
Mahaffey, K.W.2
Neal, B.3
-
78
-
-
85020040943
-
Cardiovascular protection by sodium glucose cotransporter 2 inhibitors: Potential mechanisms
-
Staels B. Cardiovascular protection by sodium glucose cotransporter 2 inhibitors: potential mechanisms. Am J Med 2017; 130: S30-S39
-
(2017)
Am J Med
, vol.130
, pp. S30-S39
-
-
Staels, B.1
-
79
-
-
84975775560
-
The failing heart relies on ketone bodies as a fuel
-
Aubert G, Martin OJ, Horton JL et al. The failing heart relies on ketone bodies as a fuel. Circulation 2016; 133: 698-705
-
(2016)
Circulation
, vol.133
, pp. 698-705
-
-
Aubert, G.1
Martin, O.J.2
Horton, J.L.3
-
81
-
-
84981185386
-
Heart failure with preserved ejection fraction: A kidney disorder?
-
Fang JC. Heart failure with preserved ejection fraction: a kidney disorder? Circulation 2016; 134: 435-437
-
(2016)
Circulation
, vol.134
, pp. 435-437
-
-
Fang, J.C.1
-
82
-
-
85062019230
-
-
10 September 2018, date last accessed
-
www.empakidney.org (10 September 2018, date last accessed)
-
-
-
-
85
-
-
85041180129
-
How does empagliflozin reduce cardiovascular mortality? Insights from a mediation analysis of the EMPA-REG OUTCOME trial
-
Inzucchi SE, Zinman B, Fitchett D et al. How does empagliflozin reduce cardiovascular mortality? insights from a mediation analysis of the EMPA-REG OUTCOME trial. Diabetes Care 2018; 41: 356-363
-
(2018)
Diabetes Care
, vol.41
, pp. 356-363
-
-
Inzucchi, S.E.1
Zinman, B.2
Fitchett, D.3
-
86
-
-
85042792101
-
Empagliflozin and clinical outcomes in patients with type 2 diabetes, established cardiovascular disease and chronic kidney disease
-
Wanner C, Lachin JM, Inzucchi SE et al. Empagliflozin and clinical outcomes in patients with type 2 diabetes, established cardiovascular disease and chronic kidney disease. Circulation 2017; 132: 119-129
-
(2017)
Circulation
, vol.132
, pp. 119-129
-
-
Wanner, C.1
Lachin, J.M.2
Inzucchi, S.E.3
-
87
-
-
85021054097
-
Safety and tolerability of empagliflozin in patients with type 2 diabetes: Pooled analysis of Phase I-III clinical trials
-
Kohler S, Zeller C, Iliev H et al. Safety and tolerability of empagliflozin in patients with type 2 diabetes: pooled analysis of Phase I-III clinical trials. Adv Ther 2017; 34: 1707-1726
-
(2017)
Adv Ther
, vol.34
, pp. 1707-1726
-
-
Kohler, S.1
Zeller, C.2
Iliev, H.3
|