Preanalytical challenges-time for solutions

Clinical Chemistry and Laboratory Medicine

Volumn 57, Issue 7, 2019, Pages 974-981

  Lippi, Giuseppe ^a   Betsou, Fay ^b   Cadamuro, Janne ^c   Cornes, Michael ^d   Fleischhacker, Michael ^e   Fruekilde, Palle ^f   Neumaier, Michael ^g   Nybo, Mads ^f   Padoan, Andrea ^h   Plebani, Mario ^h   Sciacovelli, Laura ^h   Vermeersch, Pieter ⁱ   Von Meyer, Alexander ^j   Simundic, Ana Maria ^k  

^a UNIVERSITY HOSPITAL OF VERONA   (Italy)

^b INTEGRATED BIOBANK OF LUXEMBOURG   (Luxembourg)

^c PARACELSUS MEDICAL UNIVERSITY   (Austria)

^d WORCESTERSHIRE ACUTE HOSPITALS NHS TRUST   (United Kingdom)

^e German Red Cross Hospital   (Germany)

^f ODENSE UNIVERSITY HOSPITAL   (Denmark)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h UNIVERSITY HOSPITAL OF PADOVA   (Italy)

ⁱ UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^j Kliniken Nordoberpfalz and Klinikum St Marien   (Germany)

^k Croatian Academy of Medical Sciences   (Croatia)

more..

Author keywords

education; errors; laboratory medicine; preanalytical phase; quality

Indexed keywords

ARTICLE; CLINICAL CHEMISTRY; CONTROLLED STUDY; EDUCATION; ERROR; EUROPE; FECES ANALYSIS; HEMATOLOGY; HUMAN; HUMAN EXPERIMENT; LABORATORY AUTOMATION; MASS SPECTROMETRY; NEXT GENERATION SEQUENCING; PRE-ANALYTICAL PHASE; SAMPLING; BLOOD SAMPLING; CHEMISTRY; DEVICES; FECES; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABORATORY TECHNIQUE; PROCEDURES; QUALITY CONTROL; SPECIMEN HANDLING;

AUTOMATION, LABORATORY; BLOOD SPECIMEN COLLECTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLINICAL LABORATORY TECHNIQUES; FECES; HEMOLYSIS; HUMANS; MASS SPECTROMETRY; PRE-ANALYTICAL PHASE; QUALITY CONTROL; SPECIMEN HANDLING;

EID: 85061125814     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2018-1334     Document Type: Article

References (44)

1. Cornes MP, Church S, van Dongen-Lases E, Grankvist K, Guimaraes JT, Ibarz M, et al. The role of European Federation of Clinical Chemistry and Laboratory Medicine Working Group for Preanalytical Phase in standardization and harmonization of the preanalytical phase in Europe. Ann Clin Biochem 2016;53:539-47.
2. Lippi G, Simundic AM. The EFLM strategy for harmonization of the preanalytical phase. Clin Chem Lab Med 2018;56:1660-6.
3. Lippi G, Chance JJ, Church S, Dazzi P, Fontana R, Giavarina D, et al. Preanalytical quality improvement: From dream to reality. Clin Chem Lab Med 2011;49:1113-26.
4. Lippi G, Becan-McBride K, Behulova D, Bowen RA, Church S, Delanghe J, et al. Preanalytical quality improvement: In quality we trust. Clin Chem Lab Med 2013;51:229-41.
5. Lippi G, Banfi G, Church S, Cornes M, De Carli G, Grankvist K, et al. Preanalytical quality improvement. In pursuit of harmony, on behalf of European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE). Clin Chem Lab Med 2015;53:357-70.
6. Lippi G, Baird GS, Banfi G, Bolenius K, Cadamuro J, Church S, et al. Improving quality in the preanalytical phase through innovation, on behalf of the European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE). Clin Chem Lab Med 2017;55:489-500.
7. Hawker CD. Nonanalytic laboratory automation: A quarter century of progress. Clin Chem 2017;63:1074-82.
8. Lou AH, Elnenaei MO, Sadek I, Thompson S, Crocker BD, Nassar B. Evaluation of the impact of a total automation system in a large core laboratory on turnaround time. Clin Biochem 2016;49:1254-8.
9. Carraro P, Plebani M. Errors in a stat laboratory: Types and frequencies 10 years later. Clin Chem 2007;53:1338-42.
10. Jensen E, Blaabjerg O, Petersen PH, Hegedus L. Sampling time is important but may be overlooked in establishment and use of thyroid-stimulating hormone reference intervals. Clin Chem 2007;53:355-6.
11. Schumacher GE. Choosing optimal sampling times for therapeutic drug monitoring. Clin Pharm 1985;4:84-92.
12. Montagnana M, Salvagno GL, Lippi G. Circadian variation within hemostasis: An underrecognized link between biology and disease Semin Thromb Hemost 2009;35:23-33.
13. Cadamuro J, Gaksch M, Wiedemann H, Lippi G, von Meyer A, Pertersmann A, et al. Are laboratory tests always needed Frequency and causes of laboratory overuse in a hospital setting. Clin Biochem 2018;54:85-91.
14. Horvath A. From evidence to best practice in laboratory medicine. Clin Biochem Rev 2013;34:47-60.
15. Cadamuro J, Ibarz M, Cornes M, Nybo M, Haschke-Becher E, von Meyer A, et al. Managing inappropriate utilization of laboratory resources. Diagnosis (Berl) 2019;6:5-13.
16. Buoro S, Lippi G. Harmonization of laboratory hematology: A long and winding journey. Clin Chem Lab Med 2018;56: 1575-8.
17. Banfi G, Salvagno GL, Lippi G. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med 2007;45:565-76.
18. Lippi G, Plebani M. EDTA-dependent pseudothrombocytopenia: Further insights and recommendations for prevention of a clinically threatening artifact. Clin Chem Lab Med 2012;50:1281-5.
19. Rapi S, Cellai F, Rubeca R. Is it possible to correctly assess the pre-analytical characteristics of faecal tests J Lab Precis Med 2018;3:1.
20. Padoan A, D' Inca R, Scapellato ML, De Bastiani R, Caccaro R, Mescoli C, et al. Improving IBD diagnosis and monitoring by understanding preanalytical, analytical and biological fecal calprotectin variability. Clin Chem Lab Med 2018;56:1926-35.
21. Cadamuro J, Simundic AM, Ajzner E, Sandberg S. A pragmatic approach to sample acceptance and rejection. Clin Biochem 2017;50:579-81.
22. von Meyer A, Cadamuro J, Lippi G, Simundic AM. Call for more transparency in manufacturers declarations on serum indices: On behalf of the Working Group for Preanalytical Phase (WGPRE), European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). Clin Chim Acta 2018;484:328-32.
23. Lippi G, Cadamuro J, von Meyer A, Simundic AM. European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE). Practical recommendations for managing hemolyzed samples in clinical chemistry testing. Clin Chem Lab Med 2018;56:718-27.
24. Lippi G, Cadamuro J, von Meyer A, Simundic AM, European Federation of Clinical Chemistry, Laboratory Medicine (EFLM) Working Group; for Preanalytical Phase (WG-PRE). Local quality assurance of serum or plasma (HIL) indices. Clin Biochem 2018;54:112-8.
25. Gomez Rioja R, Martinez Espartosa D, Segovia M, Ibarz M, Llopis MA, Bauca JM, et al. Laboratory sample stability. Is it possible to define a consensus stability function An example of five blood magnitudes. Clin Chem Lab Med 2018;56:1806-18.
26. Oddoze C, Lombard E, Portugal H. Stability study of 81 analytes in human whole blood, in serum and in plasma. Clin Biochem 2012;45:464-9.
27. STARD guidelines. Available from: Http://www.equator-network. org/reporting-guidelines/stard/. Accessed 19 Oct 2018.
28. Sciacovelli L, Panteghini M, Lippi G, Sumarac Z, Cadamuro J, Galoro CA, et al. Defining a roadmap for harmonizing quality indicators in Laboratory Medicine: A consensus statement on behalf of the IFCC Working Group "Laboratory Error and Patient Safety" and EFLM Task and Finish Group "Performance specifications for the extra-analytical phases". Clin Chem Lab Med 2017;55:1478-88.
29. Plebani M, Sciacovelli L, Aita A, Pelloso M, Chiozza ML. Performance criteria and quality indicators for the pre-analytical phase. Clin Chem Lab Med 2015;53:943-8.
30. Plebani M, Sciacovelli L, Aita A. Quality indicators for the total testing process. Clin Lab Med 2017;37:187-205.
31. Grebe SK, Singh RJ. LC-MS/MS in the clinical laboratory-where to from here Clin Biochem Rev 2011;32:5-31.
32. Salvagno GL, Danese E, Lippi G. Preanalytical variables for liquid chromatography-mass spectrometry (LC-MS) analysis of human blood specimens. Clin Biochem 2017;50:582-6.
33. Yin P, Lehmann R, Xu G. Effects of pre-analytical processes on blood samples used in metabolomics studies. Anal Bioanal Chem 2015;407:4879-92.
34. Heitzer E, Haque IS, Roberts CE, Speicher MR. Current and future perspectives of liquid biopsies in genomics-driven oncology. Nat Rev Genet 2018 Nov 8. doi: 10.1038/s41576-018-0071-5. [Epub ahead of print].
35. Jung K, Fleischhacker M, Rabien A. Cell-free DNA in the blood as a solid tumor biomarker-a critical appraisal of the literature. Clin Chim Acta 2010;411:1611-24.
36. Schmidt B, Reinicke D, Reindl I, Bork I, Wollschlager B, Lambrecht N, et al. Liquid biopsy-Performance of the PAXgeneR blood ccfDNA tubes for the isolation and characterization of cell-free plasma DNA from tumor patients. Clin Chim Acta 2017;469:94-8.
37. Betsou F. Biospecimen processing method validation. Biopreserv Biobank 2015;13:69.
38. Gaignaux A, Ashton G, Coppola D, De Souza Y, De Wilde A, Eliason J, et al. A biospecimen proficiency testing program for biobank accreditation: Four years of experience. Biopreserv Biobank 2016;14:429-39.
39. Betsou F, Bulla A, Cho SY, Clements J, Chuaqui R, Coppola D, et al. Assays for qualification and quality stratification of clinical biospecimens used in research. Biopreserv Biobank 2016;14:398-409.
40. Lundberg GD. Managing the patient-focused laboratory. Oradell, NJ: Medical Economics Co, 1975:9-42.
41. 41., erson NL, Anderson NG. The human plasma proteome: History, character, and diagnostic prospects. Mol Cell Proteomics 2002;1:845-67.
42. Zimmer JS, Dyckes DF, Bernlohr DA, Murphy RC. Fatty acid binding proteins stabilize leukotriene A4: Competition with arachidonic acid but not other lipoxygenase products. J Lipid Res 2004;45:2138-44.
43. Thelen MH, Huisman W. Harmonization of accreditation to ISO15189. Clin Chem Lab Med 2018;56:1637-43.
44. Antonelli G, Padoan A, Aita A, Sciacovelli L, Plebani M. Verification of examination procedures in clinical laboratory for imprecision, trueness and diagnostic accuracy according to ISO 15189:2012: A pragmatic approach. Clin Chem Lab Med 2017;55:1501-8.