Fatty acid binding proteins stabilize leukotriene A4: Competition with arachidonic acid but not other lipoxygenase products

Journal of Lipid Research

Volumn 45, Issue 11, 2004, Pages 2138-2144

  Dickinson Zimmer, Jennifer S ^a,b   Dyckes, Douglas F ^c   Bernlohr, David A ^d   Murphy, Robert C ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Half life; Leukotriene biosynthesis; Transcellular biosynthesis

Indexed keywords

5 HYDROXYICOSATETRAENOIC ACID; 5,6 DIHYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; ARACHIDONIC ACID; FATTY ACID BINDING PROTEIN; LEUKOTRIENE A4; LIPOXYGENASE; MYOGLOBIN; UNCLASSIFIED DRUG; 5,6 DIHYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; 5,6-DIHYDROXY-7,9,11,14-EICOSATETRAENOIC ACID; 5-HYDROXY-6,8,11,14-EICOSATETRAENOIC ACID; CARRIER PROTEIN; HYDROXYICOSATETRAENOIC ACID;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; FATTY ACID SYNTHESIS; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; MAST CELL LEUKEMIA; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN STABILITY; RAT; TEMPERATURE; ANIMAL; BIOCHEMISTRY; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; DOSE RESPONSE; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; TIME;

ANIMALS; ARACHIDONIC ACID; BINDING SITES; BINDING, COMPETITIVE; BIOCHEMISTRY; CARRIER PROTEINS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACID-BINDING PROTEINS; HYDROGEN-ION CONCENTRATION; HYDROXYEICOSATETRAENOIC ACIDS; LEUKOTRIENE A4; LIPOXYGENASE; MASS SPECTROMETRY; MODELS, BIOLOGICAL; PROTEIN BINDING; RATS; TEMPERATURE; TIME FACTORS;

EID: 21644440188     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M400240-JLR200     Document Type: Article

References (37)

1. 2 activation. J. Leukoc. Biol. 65: 330-336.
2. 2 in eicosanoid generation. Am. J. Respir. Crit. Care Med. 161 (Suppl.): 32-35.
3. Ford-Hutchinson, A. W., M. Gresser, and R. N. Young. 1994. 5-Lipoxygenase. Annu. Rev. Biochem. 63: 383-417.
4. Brock, T. G., R. Paine III, and M. Peters-Golden. 1994. Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells. J. Biol. Chem. 269: 22059-22066.
5. Rouzer, C., and S. Kargman. 1988. Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J. Biol. Chem. 263: 10980-10988.
6. Miller, D. K., J. W. Gillard, P. J. Vickers, S. Sadowski, C. Léveillé, J. A. Mancini, P. Charleson, R. A. F. Dixon, A. W. Ford-Hutchinson, R. Fortin, J. Y. Gauthier, J. Rodkey, R. Rosen, C. Rouzer, I. S. Sigal, C. D. Strader, and J. F. Evans. 1990. Identification and isolation of a membrane protein necessary for leukotriene production. Nature. 343: 278-281.
7. Mancini, J. A., M. Abramovitz, M. E. Cox, E. Wong, S. Charleson, H. Perrier, Z. Wang, P. Prasit, and P. J. Vickers. 1993. 5-Lipoxygenase-activating protein is an arachidonate binding protein. FEBS Lett. 318: 277-281.
8. Shimizu, T., O. Rådmark, and B. Samuelsson. 1984. Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc. Natl. Acad. Sci. USA. 81: 689-693.
9. 4 hydrolase. Prostaglandins Other Lipid Med. 68-69: 495-510.
10. 4 synthase. Prostaglandins Leukot. Essent. Fatty Acids. 69: 111-116.
11. 4. J. Biol. Chem. 257: 4680-4683.
12. Borgeat, P., and B. Samuelsson. 1979. Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. Proc. Natl. Acad. Sci. USA. 76: 3213-3217.
13. 4 by epithelial fatty acid binding protein in the rat basophilic leukemia cell. J. Biol. Chem. 279: 7420-7426.
14. Kane, C. D., N. Ribarik Coe, B. Vanlandingham, P. Krieg, and D. A. Bernlohr. 1996. Expression, purification, and ligand-binding analysis of recombinant keratinocyte lipid-binding protein (MAL-1), an intracellular lipid-binding protein overexpressed in neoplastic skin cells. Biochemistry. 35: 2894-2900.
15. Widstrom, R. L., A. W. Norris, and A. A. Spector. 2001. Binding of cytochrome P450 and lipoxygenase pathway products by heart fatty acid-binding protein. Biochemistry. 40: 1070-1076.
16. Widstrom, R. L., A. W. Norris, J. Van Der Veer, and A. A. Spector. 2003. Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase. Biochemistry. 42: 11762-11767.
17. Storch, J., and A. E. A. Thumser. 2000. The fatty acid transport function of fatty acid-binding proteins. Biochim. Biophys. Acta. 1486: 28-44.
18. Sacchettini, J. C., J. I. Gordon, and L. J. Banaszak. 1989. Crystal structure of rat intestinal fatty-acid-binding protein. Refinement and analysis of the Escherichia coli-derived protein with bound palmitate. J. Mol. Biol. 208: 327-339.
19. Zimmerman, A. W., H. T. B. van Moerkerk, and J. H. Veerkamp. 2001. Ligand specificity and conformational stability of human fatty acid-binding proteins. Int. J. Biochem. Cell Biol. 33: 865-876.
20. Glatz, J. F. C., J. J. F. P. Luiken, M. van Bilsen, and G. J. van der Vusse. 2002. Cellular lipid binding proteins as facilitators and regulators of lipid metabolism. Mol. Cell. Biochem. 239: 3-7.
21. 4 obtained from hydrolysis of its methyl ester. Prostaglandins Leukot. Essent. Fatty Acids. 34: 27-30.
22. Jenkins-Kruchten, A. E., A. Bennars-Eiden, J. R. Ross, W. J. Shen, F. B. Kraemer, and D. A. Bernlohr. 2003. Fatty acid binding protein-hormone sensitive lipase interaction: fatty acid dependence on binding. J. Biol. Chem. 278: 47636-47643.
23. 4 and other chemically reactive metabolites of arachidonic acid. J. Am. Soc. Mass Spectrom. 13: 1227-1234.
24. Hertzel, A. V., and D. A. Bernlohr. 2000. The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol. Metab. 11: 175-180.
25. Guthmann, F., C. Hohoff, H. Fechner, P. Humber, T. Börchers, F. Spener, and B. Rüstow. 1998. Expression of fatty-acid-binding-proteins in cells involved in lung-specific lipid metabolism. Eur. J. Biochem. 253: 430-436.
26. Owada, Y., S. A. Abdelwahab, R. Suzuki, H. Iwasa, and H. Sakagami. 2001. Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung. Histochem. J. 33: 453-457.
27. Bigby, T. D., and N. Meslier. 1989. Transcellular lipoxygenase metabolism between monocytes and platelets. J. Immunol. 143: 1948-1954.
28. Ockner, R. K., J. A. Manning, and J. P. Kane. 1982. Fatty acid binding protein: isolation from rat liver, characterization and immunochemical quantification. J. Biol. Chem. 257: 7872-7878.
29. 4. Arch. Biochem. Biophys. 305: 378-384.
30. Fukai, F., Y. Suzuki, Y. Nishizawa, and T. Katayama. 1996. Transcellular biosynthesis of cysteinyl leukotrienes by Kupffer cell-hepatocyte cooperation in rat liver. Cell Biol. Int. 20: 423-428.
31. Antohe, F., D. Popov, L. Radulescu, N. Simionescu, T. Borchers, F. Spener, and M. Simionescu. 1998. Heart microvessels and aortic endothelial cells express the 15kDa heart-type fatty acid-binding proteins. Eur. J. Cell Biol. 76: 102-109.
32. 4 synthesized by polymorphonuclear leukocytes. J. Biol. Chem. 264: 16466-16472.
33. Sala, A., G. Rossoni, F. Berti, C. Buccellati, A. Bonazzi, J. Maclouf, and G. Folco. 2000. Monoclonal anti-CD18 antibody prevents transcellular biosynthesis of cysteinyl leukotrienes in vitro and in vivo and protects against leukotriene-dependent increase in coronary vascular resistance and myocardial stiffness. Circulation. 101: 1436-1440.
34. Coe, N. R., and D. A. Bernlohr. 1998. Physiological properties and functions of intracellular fatty acid-binding proteins. Biochim. Biophys. Acta. 1391: 287-306.
35. Alonso, F., P. M. Henson, and C. C. Leslie. 1986. A cytosolic phospholipase in human neutrophils that hydrolyzes arachidonoyl-containing phosphatidylcholine. Biochim. Biophys. Acta. 878: 273-280.
36. Chilton, F. H., and R. C. Murphy. 1986. Remodeling of arachidonate-containing phosphoglycerides within the human neutrophil. J. Biol. Chem. 261: 7771-7777.
37. Wong, A., M. N. Cook, J. P. Foley, H. M. Sarau, and S. M. Hwang. 1991. Influx of extracellular calcium is required for the membrane translocation of 5-lipoxygenase and leukotriene synthesis. Biochemistry. 30: 9346-9354.