Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 52, 2018, Pages E12363-E12369

  Zanini, Fabio ^a   Robinson, Makeda L ^b   Croote, Derek ^a   Sahoo, Malaya Kumar ^b   Sanz, Ana Maria ^c   Ortiz Lasso, Eliana ^c   Albornoz, Ludwig Luis ^c   Rosso, Fernando ^c   Montoya, Jose G ^b   Goo, Leslie ^d   Pinsky, Benjamin A ^b   Quake, Stephen R ^a,d,e   Einav, Shirit ^b  

^a Stanford University   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FUNDACIÓN VALLE DEL LILI   (Colombia)

^d CHAN ZUCKERBERG BIOHUB   (United States)

^e STANFORD UNIVERSITY   (United States)

Author keywords

Biomarkers; Dengue; Single cell; Transcriptomics; Virus host interactions

Indexed keywords

BIOLOGICAL MARKER; CD14 ANTIGEN; CD16 ANTIGEN; CD163 ANTIGEN; CD69 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; IMMUNOGLOBULIN M; INTERFERON; TRANSCRIPTOME; VIRUS RNA;

ARTICLE; B LYMPHOCYTE; BIODIVERSITY; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; DISEASE COURSE; DISEASE SEVERITY; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKOCYTE; MONOCYTE; NONHUMAN; PLASMABLAST; PRIORITY JOURNAL; RNA SEQUENCE; RNA VIRUS; SINGLE CELL ANALYSIS; UPREGULATION; ADULT; BLOOD; DISEASE EXACERBATION; FEMALE; GENETICS; IMMUNOLOGY; MALE; METABOLISM; MONONUCLEAR CELL; PLASMA CELL; PROCEDURES; SEQUENCE ANALYSIS; SEVERE DENGUE; VIROLOGY; VIRUS REPLICATION;

ADULT; B-LYMPHOCYTES; BIOMARKERS; DENGUE; DENGUE VIRUS; DISEASE PROGRESSION; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MONOCYTES; PLASMA CELLS; RNA VIRUSES; RNA, VIRAL; SEQUENCE ANALYSIS, RNA; SEVERE DENGUE; SINGLE-CELL ANALYSIS; TRANSCRIPTOME; VIRUS REPLICATION;

EID: 85059214054     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1813819115     Document Type: Article

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