-
1
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter,D., MacArthur,J., Morales,J., Burdett,T., Hall,P., Junkins,H., Klemm,A., Flicek,P., Manolio,T., Hindorff,L. et al. (2014) The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res., 42, D1001–D1006.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D1001-D1006
-
-
Welter, D.1
MacArthur, J.2
Morales, J.3
Burdett, T.4
Hall, P.5
Junkins, H.6
Klemm, A.7
Flicek, P.8
Manolio, T.9
Hindorff, L.10
-
2
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher,P.M., Brown,M.A., McCarthy,M.I. and Yang,J. (2012) Five years of GWAS discovery. Am. J. Hum. Genet., 90, 7–24.
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
3
-
-
84873086126
-
Chromatin marks identify critical cell types for fine mapping complex trait variants
-
Trynka,G., Sandor,C., Han,B., Xu,H., Stranger,B.E., Liu,X.S. and Raychaudhuri,S. (2013) Chromatin marks identify critical cell types for fine mapping complex trait variants. Nat. Genet., 45, 124–130.
-
(2013)
Nat. Genet.
, vol.45
, pp. 124-130
-
-
Trynka, G.1
Sandor, C.2
Han, B.3
Xu, H.4
Stranger, B.E.5
Liu, X.S.6
Raychaudhuri, S.7
-
4
-
-
85035746107
-
Estimating the causal tissues for complex traits and diseases
-
Ongen,H., Brown,A.A., Delaneau,O., Panousis,N.I., Nica,A.C. and Dermitzakis,E.T. (2017) Estimating the causal tissues for complex traits and diseases. Nat. Genet., 49, 1676–1683.
-
(2017)
Nat. Genet.
, vol.49
, pp. 1676-1683
-
-
Ongen, H.1
Brown, A.A.2
Delaneau, O.3
Panousis, N.I.4
Nica, A.C.5
Dermitzakis, E.T.6
-
5
-
-
84948686586
-
Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci
-
Martin,P., McGovern,A., Orozco,G., Duffus,K., Yarwood,A., Schoenfelder,S., Cooper,N.J., Barton,A., Wallace,C., Fraser,P. et al. (2015) Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci. Nat. Commun., 6, 10069.
-
(2015)
Nat. Commun.
, vol.6
, pp. 10069
-
-
Martin, P.1
McGovern, A.2
Orozco, G.3
Duffus, K.4
Yarwood, A.5
Schoenfelder, S.6
Cooper, N.J.7
Barton, A.8
Wallace, C.9
Fraser, P.10
-
6
-
-
2142708114
-
A short history of a short RNA
-
Lee,R., Feinbaum,R. and Ambros,V. (2004) A short history of a short RNA. Cell, 116, S89–S92.
-
(2004)
Cell
, vol.116
, pp. S89-S92
-
-
Lee, R.1
Feinbaum, R.2
Ambros, V.3
-
7
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
Lee,R.C. and Ambros,V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science, 294, 862–864.
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
8
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu,J., Getz,G., Miska,E.A., Alvarez-Saavedra,E., Lamb,J., Peck,D., Sweet-Cordero,A., Ebert,B.L., Mak,R.H., Ferrando,A.A. et al. (2005) MicroRNA expression profiles classify human cancers. Nature, 435, 834–838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
-
9
-
-
79952134938
-
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn’s disease
-
Brest,P., Lapaquette,P., Souidi,M., Lebrigand,K., Cesaro,A., Vouret-Craviari,V., Mari,B., Barbry,P., Mosnier,J.-F., Hébuterne,X. et al. (2011) A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn’s disease. Nat. Genet., 43, 242–245.
-
(2011)
Nat. Genet.
, vol.43
, pp. 242-245
-
-
Brest, P.1
Lapaquette, P.2
Souidi, M.3
Lebrigand, K.4
Cesaro, A.5
Vouret-Craviari, V.6
Mari, B.7
Barbry, P.8
Mosnier, J.-F.9
Hébuterne, X.10
-
10
-
-
28444469246
-
Silencing of microRNAs in vivo with ‘antagomirs’
-
Krützfeldt,J., Rajewsky,N., Braich,R., Rajeev,K.G., Tuschl,T., Manoharan,M. and Stoffel,M. (2005) Silencing of microRNAs in vivo with ‘antagomirs’. Nature, 438, 685–689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krützfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
11
-
-
85017125259
-
The race of 10 synthetic RNAi-based drugs to the pharmaceutical market
-
Titze-de-Almeida,R., David,C. and Titze-de-Almeida,S.S. (2017) The race of 10 synthetic RNAi-based drugs to the pharmaceutical market. Pharm. Res., 34, 1339–1363.
-
(2017)
Pharm. Res.
, vol.34
, pp. 1339-1363
-
-
Titze-De-Almeida, R.1
David, C.2
Titze-De-Almeida, S.S.3
-
12
-
-
85028474852
-
An integrated expression atlas of miRNAs and their promoters in human and mouse
-
De Rie,D., Abugessaisa,I., Alam,T., Arner,E., Arner,P., Ashoor,H., Åström,G., Babina,M., Bertin,N., Burroughs,A.M. et al. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nat. Biotechnol., 35, 872–878.
-
(2017)
Nat. Biotechnol.
, vol.35
, pp. 872-878
-
-
De Rie, D.1
Abugessaisa, I.2
Alam, T.3
Arner, E.4
Arner, P.5
Ashoor, H.6
Åström, G.7
Babina, M.8
Bertin, N.9
Burroughs, A.M.10
-
13
-
-
84959477574
-
Significant impact of miRNA – Target gene networks on genetics of human complex traits
-
Okada,Y., Muramatsu,T., Suita,N., Kanai,M., Kawakami,E., Iotchkova,V., Soranzo,N. and Inazawa,J. (2016) Significant impact of miRNA – target gene networks on genetics of human complex traits. Sci. Rep., 6, 22223.
-
(2016)
Sci. Rep.
, vol.6
, pp. 22223
-
-
Okada, Y.1
Muramatsu, T.2
Suita, N.3
Kanai, M.4
Kawakami, E.5
Iotchkova, V.6
Soranzo, N.7
Inazawa, J.8
-
14
-
-
77957342306
-
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
-
Ayellet,V.S., Groop,L., Mootha,V.K., Daly,M.J. and Altshuler,D. (2010) Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet., 6, e1001058.
-
(2010)
PLoS Genet
, vol.6
, pp. e1001058
-
-
Ayellet, V.S.1
Groop, L.2
Mootha, V.K.3
Daly, M.J.4
Altshuler, D.5
-
15
-
-
84933278837
-
Construction of a population-specific HLA imputation reference panel and its application to Graves’ disease risk in Japanese
-
Okada,Y., Momozawa,Y., Ashikawa,K., Kanai,M., Matsuda,K., Kamatani,Y., Takahashi,A. and Kubo,M. (2015) Construction of a population-specific HLA imputation reference panel and its application to Graves’ disease risk in Japanese. Nat. Genet., 47, 798–802.
-
(2015)
Nat. Genet.
, vol.47
, pp. 798-802
-
-
Okada, Y.1
Momozawa, Y.2
Ashikawa, K.3
Kanai, M.4
Matsuda, K.5
Kamatani, Y.6
Takahashi, A.7
Kubo, M.8
-
16
-
-
84966318838
-
Distribution of miRNA expression across human tissues
-
Ludwig,N., Leidinger,P., Becker,K., Backes,C., Fehlmann,T., Pallasch,C., Rheinheimer,S., Meder,B., Stähler,C., Meese,E. et al. (2016) Distribution of miRNA expression across human tissues. Nucleic Acids Res., 44, 3865–3877.
-
(2016)
Nucleic Acids Res
, vol.44
, pp. 3865-3877
-
-
Ludwig, N.1
Leidinger, P.2
Becker, K.3
Backes, C.4
Fehlmann, T.5
Pallasch, C.6
Rheinheimer, S.7
Meder, B.8
Stähler, C.9
Meese, E.10
-
17
-
-
85016438418
-
Overview of the BioBank Japan Project: Study design and profile
-
Nagai,A., Hirata,M., Kamatani,Y., Muto,K., Matsuda,K., Kiyohara,Y., Ninomiya,T., Tamakoshi,A., Yamagata,Z., Mushiroda,T. et al. (2017) Overview of the BioBank Japan Project: Study design and profile. J. Epidemiol., 27, S2–S8.
-
(2017)
J. Epidemiol.
, vol.27
, pp. S2-S8
-
-
Nagai, A.1
Hirata, M.2
Kamatani, Y.3
Muto, K.4
Matsuda, K.5
Kiyohara, Y.6
Ninomiya, T.7
Tamakoshi, A.8
Yamagata, Z.9
Mushiroda, T.10
-
18
-
-
85016420191
-
Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases
-
Hirata,M., Kamatani,Y., Nagai,A., Kiyohara,Y., Ninomiya,T., Tamakoshi,A., Yamagata,Z., Kubo,M., Muto,K., Mushiroda,T. et al. (2017) Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases. J. Epidemiol., 27, S9–S21.
-
(2017)
J. Epidemiol.
, vol.27
, pp. S9-S21
-
-
Hirata, M.1
Kamatani, Y.2
Nagai, A.3
Kiyohara, Y.4
Ninomiya, T.5
Tamakoshi, A.6
Yamagata, Z.7
Kubo, M.8
Muto, K.9
Mushiroda, T.10
-
19
-
-
77956055481
-
Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative
-
Aletaha,D., Neogi,T., Silman,A.J., Funovits,J., Felson,D.T., Bingham,C.O., Birnbaum,N.S., Burmester,G.R., Bykerk,V.P., Cohen,M.D. et al. (2010) 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum., 62, 2569–2581.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.2010
, pp. 2569-2581
-
-
Aletaha, D.1
Neogi, T.2
Silman, A.J.3
Funovits, J.4
Felson, D.T.5
Bingham, C.O.6
Birnbaum, N.S.7
Burmester, G.R.8
Bykerk, V.P.9
Cohen, M.D.10
-
20
-
-
84979648921
-
Evaluation of microRNA alignment techniques
-
Ziemann,M., Kaspi,A. and El-Osta,A. (2016) Evaluation of microRNA alignment techniques. RNA, 22, 1120–1138.
-
(2016)
RNA
, vol.22
, pp. 1120-1138
-
-
Ziemann, M.1
Kaspi, A.2
El-Osta, A.3
-
21
-
-
84894288992
-
Genetics of rheumatoid arthritis contributes to biology and drug discovery
-
Okada,Y., Wu,D., Trynka,G., Raj,T., Terao,C., Ikari,K., Kochi,Y., Ohmura,K., Suzuki,A., Yoshida,S. et al. (2014) Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature, 506, 376–381.
-
(2014)
Nature
, vol.506
, pp. 376-381
-
-
Okada, Y.1
Wu, D.2
Trynka, G.3
Raj, T.4
Terao, C.5
Ikari, K.6
Kochi, Y.7
Ohmura, K.8
Suzuki, A.9
Yoshida, S.10
-
22
-
-
84994175707
-
Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis
-
Okada,Y., Suzuki,A., Ikari,K., Terao,C., Kochi,Y., Ohmura,K., Higasa,K., Akiyama,M., Ashikawa,K., Kanai,M. et al. (2016) Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis. Am. J. Hum. Genet., 99, 366–374.
-
(2016)
Am. J. Hum. Genet.
, vol.99
, pp. 366-374
-
-
Okada, Y.1
Suzuki, A.2
Ikari, K.3
Terao, C.4
Kochi, Y.5
Ohmura, K.6
Higasa, K.7
Akiyama, M.8
Ashikawa, K.9
Kanai, M.10
-
23
-
-
85031313737
-
Genetic effects on gene expression across human tissues
-
GTEx Consortium. (2017) Genetic effects on gene expression across human tissues. Nature, 550, 204–213.
-
(2017)
Nature
, vol.550
, pp. 204-213
-
-
-
24
-
-
85008490305
-
The genetic architecture of gene expression in peripheral blood
-
Lloyd-Jones,L.R., Holloway,A., McRae,A., Yang,J., Small,K., Zhao,J., Zeng,B., Bakshi,A., Metspalu,A., Dermitzakis,M. et al. (2017) The genetic architecture of gene expression in peripheral blood. Am. J. Hum. Genet., 100, 228–237.
-
(2017)
Am. J. Hum. Genet.
, vol.100
, pp. 228-237
-
-
Lloyd-Jones, L.R.1
Holloway, A.2
McRae, A.3
Yang, J.4
Small, K.5
Zhao, J.6
Zeng, B.7
Bakshi, A.8
Metspalu, A.9
Dermitzakis, M.10
-
25
-
-
84961927084
-
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
-
Zhu,Z., Zhang,F., Hu,H., Bakshi,A., Robinson,M.R., Powell,J.E., Montgomery,G.W., Goddard,M.E., Wray,N.R., Visscher,P.M. et al. (2016) Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat. Genet., 48, 481–487.
-
(2016)
Nat. Genet.
, vol.48
, pp. 481-487
-
-
Zhu, Z.1
Zhang, F.2
Hu, H.3
Bakshi, A.4
Robinson, M.R.5
Powell, J.E.6
Montgomery, G.W.7
Goddard, M.E.8
Wray, N.R.9
Visscher, P.M.10
-
26
-
-
84992361866
-
Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set
-
Kanai,M., Tanaka,T. and Okada,Y. (2016) Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set. J. Hum. Genet., 61, 861–866.
-
(2016)
J. Hum. Genet.
, vol.61
, pp. 861-866
-
-
Kanai, M.1
Tanaka, T.2
Okada, Y.3
-
27
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee,S.H., Wray,N.R., Goddard,M.E. and Visscher,P.M. (2011) Estimating missing heritability for disease from genome-wide association studies. Am. J. Hum. Genet., 88, 294–305.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
Visscher, P.M.4
-
28
-
-
84923946495
-
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
-
Bulik-Sullivan,B., Loh,P.R., Finucane,H.K., Ripke,S., Yang,J., Patterson,N., Daly,M.J., Price,A.L., Neale,B.M., Corvin,A. et al. (2015) LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat. Genet., 47, 291–295.
-
(2015)
Nat. Genet.
, vol.47
, pp. 291-295
-
-
Bulik-Sullivan, B.1
Loh, P.R.2
Finucane, H.K.3
Ripke, S.4
Yang, J.5
Patterson, N.6
Daly, M.J.7
Price, A.L.8
Neale, B.M.9
Corvin, A.10
-
29
-
-
84908890496
-
Defining the role of common variation in the genomic and biological architecture of adult human height
-
Wood,A.R., Esko,T., Yang,J., Vedantam,S., Pers,T.H., Gustafsson,S., Chu,A.Y., Estrada,K., Luan,J., Kutalik,Z. et al. (2014) Defining the role of common variation in the genomic and biological architecture of adult human height. Nat. Genet., 46, 1173–1186.
-
(2014)
Nat. Genet.
, vol.46
, pp. 1173-1186
-
-
Wood, A.R.1
Esko, T.2
Yang, J.3
Vedantam, S.4
Pers, T.H.5
Gustafsson, S.6
Chu, A.Y.7
Estrada, K.8
Luan, J.9
Kutalik, Z.10
-
30
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium, Mahajan,A., Go,M.J., Zhang,W., Below,J.E., Gaulton,K.J. et al. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat. Genet., 46, 234–244.
-
(2014)
Nat. Genet.
, vol.46
, pp. 234-244
-
-
Mahajan, A.1
Go, M.J.2
Zhang, W.3
Below, J.E.4
Gaulton, K.J.5
-
31
-
-
84857985148
-
The cellular and signaling networks linking the immune system and metabolism in disease
-
Osborn,O. and Olefsky,J.M. (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nat. Med., 18, 363–374.
-
(2012)
Nat. Med.
, vol.18
, pp. 363-374
-
-
Osborn, O.1
Olefsky, J.M.2
-
32
-
-
85000443086
-
Partitioning heritability by functional annotation using genome-wide association summary statistics
-
Finucane,H.K., Bulik-Sullivan,B., Gusev,A., Trynka,G., Reshef,Y., Loh,P.R., Anttila,V., Xu,H., Zang,C., Farh,K. et al. (2015) Partitioning heritability by functional annotation using genome-wide association summary statistics. Nat. Genet., 47, 1228–1235.
-
(2015)
Nat. Genet.
, vol.47
, pp. 1228-1235
-
-
Finucane, H.K.1
Bulik-Sullivan, B.2
Gusev, A.3
Trynka, G.4
Reshef, Y.5
Loh, P.R.6
Anttila, V.7
Xu, H.8
Zang, C.9
Farh, K.10
-
33
-
-
84995678205
-
The role of microRNAs in the pathogenesis of autoimmune diseases
-
Chen,J.-Q., Papp,G., Szodoray,P. and Zeher,M. (2016) The role of microRNAs in the pathogenesis of autoimmune diseases. Autoimmun. Rev., 15, 1171–1180.
-
(2016)
Autoimmun. Rev.
, vol.15
, pp. 1171-1180
-
-
Chen, J.-Q.1
Papp, G.2
Szodoray, P.3
Zeher, M.4
-
34
-
-
85002263301
-
The immunopathogenesis of seropositive rheumatoid arthritis: From triggering to targeting
-
Malmström,V., Catrina,A.I. and Klareskog,L. (2017) The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting. Nat. Rev. Immunol., 17, 60–75.
-
(2017)
Nat. Rev. Immunol.
, vol.17
, pp. 60-75
-
-
Malmström, V.1
Catrina, A.I.2
Klareskog, L.3
-
35
-
-
84995678205
-
The role of microRNAs in the pathogenesis of autoimmune diseases
-
Chen,J.-Q., Papp,G., Szodoray,P. and Zeher,M. (2016) The role of microRNAs in the pathogenesis of autoimmune diseases. Autoimmun. Rev., 15, 1171–1180.
-
(2016)
Autoimmun. Rev.
, vol.15
, pp. 1171-1180
-
-
Chen, J.-Q.1
Papp, G.2
Szodoray, P.3
Zeher, M.4
-
36
-
-
84896282373
-
MicroRNA-451 Down-Regulates neutrophil Chemotaxis via p38 MAPK
-
Murata,K., Yoshitomi,H., Furu,M., Ishikawa,M., Shibuya,H., Ito,H. and Matsuda,S. (2014) MicroRNA-451 Down-Regulates neutrophil Chemotaxis via p38 MAPK. Arthritis Rheumatol., 66, 549–559.
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 549-559
-
-
Murata, K.1
Yoshitomi, H.2
Furu, M.3
Ishikawa, M.4
Shibuya, H.5
Ito, H.6
Matsuda, S.7
-
37
-
-
85045328177
-
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
-
Finucane,H.K., Reshef,Y.A., Anttila,V., Slowikowski,K., Gusev,A., Byrnes,A., Gazal,S., Loh,P.R., Lareau,C., Shoresh,N. et al. (2018) Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat. Genet., 50, 621–629.
-
(2018)
Nat. Genet.
, vol.50
, pp. 621-629
-
-
Finucane, H.K.1
Reshef, Y.A.2
Anttila, V.3
Slowikowski, K.4
Gusev, A.5
Byrnes, A.6
Gazal, S.7
Loh, P.R.8
Lareau, C.9
Shoresh, N.10
-
38
-
-
85040945128
-
MiRTarBase update 2018: A resource for experimentally validated microRNA-target interactions
-
Chou,C.-H., Shrestha,S., Yang,C.-D., Chang,N.-W., Lin,Y.-L., Liao,K.-W., Huang,W.-C., Sun,T.-H., Tu,S.-J., Lee,W.-H. et al. (2018) miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions. Nucleic Acids Res., 46, D296–D302.
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(2018)
Nucleic Acids Res
, vol.46
, pp. D296-D302
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Chou, C.-H.1
Shrestha, S.2
Yang, C.-D.3
Chang, N.-W.4
Lin, Y.-L.5
Liao, K.-W.6
Huang, W.-C.7
Sun, T.-H.8
Tu, S.-J.9
Lee, W.-H.10
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