Proximal tubule-specific deletion of the NHE3 (Na+/H+ exchanger 3) promotes the pressure-natriuresis response and lowers blood pressure in mice

Hypertension

Volumn 72, Issue 6, 2018, Pages 1328-1336

  Li, Xiao C ^a   Soleimani, Manoocher ^b   Zhu, Dongmin ^c   Rubera, Isabelle ^d   Tauc, Michel ^d   Zheng, Xiaowen ^a,e   Zhang, Jianfeng ^a,e   Chen, Xu ^a   Zhuo, Jia L ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c No 1 Affiliated Hospital ^*  (China)

^d CNRS   (France)

^e GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Blood pressure; Hypertension; Kidney; Mice natriuresis

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AQUAPORIN; BICARBONATE; DIURETIC AGENT; ELECTROLYTE; SODIUM CHLORIDE; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2; SODIUM PROTON EXCHANGE PROTEIN 3; SLC9A3 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PH; BODY WEIGHT; CELIAC ARTERY STENOSIS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; EVIDENCE BASED PRACTICE; FEMALE; GENE DELETION; HYPERTENSION; HYPOTENSION; KIDNEY FUNCTION; KIDNEY PERFUSION; KIDNEY PROXIMAL TUBULE; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY OCCLUSION; MOUSE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SALT INTAKE; SODIUM EXCRETION; SYSTOLIC BLOOD PRESSURE; ANIMAL; BLOOD PRESSURE; GENETICS; KIDNEY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOOD PRESSURE; KIDNEY; KIDNEY TUBULES, PROXIMAL; MICE; MICE, KNOCKOUT; NATRIURESIS; SODIUM CHLORIDE, DIETARY; SODIUM-HYDROGEN EXCHANGER 3;

EID: 85058919226     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.118.10884     Document Type: Article

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