메뉴 건너뛰기




Volumn 78, Issue 3, 2019, Pages 311-319

Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ALPHA2B INTERFERON; ANAKINRA; AZATHIOPRINE; BOSUTINIB; CANAKINUMAB; CYTOSINE; DASATINIB; DEOXYRIBONUCLEASE; EPIDERMAL GROWTH FACTOR; FINGOLIMOD; GUANINE; HISTONE; IDELALISIB; IMATINIB; INTERFERON; METHOTREXATE; NINTEDANIB; OSIMERTINIB; RUXOLITINIB; TETRAHYDROLIPSTATIN; THYMINE; TOCILIZUMAB; TOFACITINIB; VANDETANIB; KARYOPHERIN ALPHA; KPNA4 PROTEIN, HUMAN; LIM KINASE; LIMK1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NAB1 PROTEIN, HUMAN; PRR12 PROTEIN, HUMAN; REPRESSOR PROTEIN;

EID: 85058877156     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2018-214127     Document Type: Article
Times cited : (83)

References (55)
  • 1
    • 84936891410 scopus 로고    scopus 로고
    • Heterogeneity of autoimmune diseases: Pathophysiologic insights from genetics and implications for new therapies
    • C ho JH, Feldman M. Heterogeneity of autoimmune diseases: Pathophysiologic insights from genetics and implications for new therapies. Nat Med 2015;21:730-8.
    • (2015) Nat Med , vol.21 , pp. 730-738
    • JH Ho, C.1    Feldman, M.2
  • 2
    • 84886591934 scopus 로고    scopus 로고
    • Clinical implications of shared genetics and pathogenesis in autoimmune diseases
    • Zhernakova A, Withoff S, Wijmenga C. Clinical implications of shared genetics and pathogenesis in autoimmune diseases. Nat Rev Endocrinol 2013;9:646-59.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 646-659
    • Zhernakova, A.1    Withoff, S.2    Wijmenga, C.3
  • 3
    • 57749193136 scopus 로고    scopus 로고
    • Detecting shared pathogenesis from the shared genetics of immune-related diseases
    • Zhernakova A, van Diemen CC, Wijmenga C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009;10:43-55.
    • (2009) Nat Rev Genet , vol.10 , pp. 43-55
    • Zhernakova, A.1    Van Diemen, C.C.2    Wijmenga, C.3
  • 4
    • 84888993757 scopus 로고    scopus 로고
    • A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci
    • Martin JE, Assassi S, Diaz-Gallo LM, et al. A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci. Hum Mol Genet 2013;22:4021-9.
    • (2013) Hum Mol Genet , vol.22 , pp. 4021-4029
    • Martin, J.E.1    Assassi, S.2    Diaz-Gallo, L.M.3
  • 5
    • 84983503786 scopus 로고    scopus 로고
    • Cross-disease meta-analysis of genome-wide association studies for systemic sclerosis and rheumatoid arthritis reveals irf4 as a new common susceptibility locus
    • L opez-Isac E, Martin JE, Assassi S, et al. Cross-disease meta-analysis of genome-wide association studies for systemic sclerosis and rheumatoid arthritis reveals irf4 as a new common susceptibility locus. Arthritis Rheumatol 2016;68:2338-44.
    • (2016) Arthritis Rheumatol , vol.68 , pp. 2338-2344
    • E Opez-Isac, L.1    Martin, J.E.2    Assassi, S.3
  • 6
    • 84969940768 scopus 로고    scopus 로고
    • A combined large-scale metaanalysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus
    • Márquez A, Vidal-Bralo L, Rodríguez-Rodríguez L, et al. A combined large-scale metaanalysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 2017;76:286-94.
    • (2017) Ann Rheum Dis , vol.76 , pp. 286-294
    • Márquez, A.1    Vidal-Bralo, L.2    Rodríguez-Rodríguez, L.3
  • 7
    • 70350003968 scopus 로고    scopus 로고
    • Common and different genetic background for rheumatoid arthritis and coeliac disease
    • C oenen MJ, Trynka G, Heskamp S, et al. Common and different genetic background for rheumatoid arthritis and coeliac disease. Hum Mol Genet 2009;18:4195-203.
    • (2009) Hum Mol Genet , vol.18 , pp. 4195-4203
    • MJ Oenen, C.1    Trynka, G.2    Heskamp, S.3
  • 8
    • 84941025159 scopus 로고    scopus 로고
    • Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
    • L i YR, Li J, Zhao SD, et al. Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nat Med 2015;21:1018-27.
    • (2015) Nat Med , vol.21 , pp. 1018-1027
    • Yr, L.I.1    Li, J.2    Zhao, S.D.3
  • 9
    • 84964772502 scopus 로고    scopus 로고
    • Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
    • E llinghaus D, Jostins L, Spain SL, et al. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nat Genet 2016;48:510-8.
    • (2016) Nat Genet , vol.48 , pp. 510-518
    • D Llinghaus, E.1    Jostins, L.2    Spain, S.L.3
  • 10
    • 84962339630 scopus 로고    scopus 로고
    • Management of connective tissue diseases associated interstitial lung disease: A review of the published literature
    • Wallace B, Vummidi D, Khanna D. Management of connective tissue diseases associated interstitial lung disease: A review of the published literature. Curr Opin Rheumatol 2016;28:236-45.
    • (2016) Curr Opin Rheumatol , vol.28 , pp. 236-245
    • Wallace, B.1    Vummidi, D.2    Khanna, D.3
  • 11
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • S tahl EA, Raychaudhuri S, Remmers EF, et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010;42:508-14.
    • (2010) Nat Genet , vol.42 , pp. 508-514
    • EA Tahl, S.1    Raychaudhuri, S.2    Remmers, E.F.3
  • 12
    • 84949097483 scopus 로고    scopus 로고
    • Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
    • Bentham J, Morris DL, Graham DSC, et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nat Genet 2015;47:1457-64.
    • (2015) Nat Genet , vol.47 , pp. 1457-1464
    • Bentham, J.1    Morris, D.L.2    Graham, D.S.C.3
  • 13
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • I nternational Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN)
    • I nternational Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcón-Riquelme ME, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008;40:204-10.
    • (2008) Nat Genet , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcón-Riquelme, M.E.2
  • 14
    • 77950243833 scopus 로고    scopus 로고
    • Multiple common variants for celiac disease influencing immune gene expression
    • Dubois PC, Trynka G, Franke L, et al. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010;42:295-302.
    • (2010) Nat Genet , vol.42 , pp. 295-302
    • Dubois, P.C.1    Trynka, G.2    Franke, L.3
  • 15
    • 77951765348 scopus 로고    scopus 로고
    • Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
    • R adstake TR, Gorlova O, Rueda B, et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 2010;42:426-9.
    • (2010) Nat Genet , vol.42 , pp. 426-429
    • TR Adstake, R.1    Gorlova, O.2    Rueda, B.3
  • 16
    • 84945485554 scopus 로고    scopus 로고
    • Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes
    • Miller FW, Chen W, O'Hanlon TP, et al. Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes. Genes Immun 2015;16:470-80.
    • (2015) Genes Immun , vol.16 , pp. 470-480
    • Miller, F.W.1    Chen, W.2    O'Hanlon, T.P.3
  • 17
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007;81:559-75.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 18
    • 84984598118 scopus 로고    scopus 로고
    • Next-generation genotype imputation service and methods
    • Das S, Forer L, Schönherr S, et al. Next-generation genotype imputation service and methods. Nat Genet 2016;48:1284-7.
    • (2016) Nat Genet , vol.48 , pp. 1284-1287
    • Das, S.1    Forer, L.2    Schönherr, S.3
  • 19
    • 61449086542 scopus 로고    scopus 로고
    • Shape-IT: New rapid and accurate algorithm for haplotype inference
    • Delaneau O, Coulonges C, Zagury JF. Shape-IT: new rapid and accurate algorithm for haplotype inference. BMC Bioinformatics 2008;9
    • (2008) BMC Bioinformatics , vol.9
    • Delaneau, O.1    Coulonges, C.2    Zagury, J.F.3
  • 20
    • 84983479616 scopus 로고    scopus 로고
    • A reference panel of 64, 976 haplotypes for genotype imputation
    • McCarthy S, Das S, Kretzschmar W, et al. A reference panel of 64, 976 haplotypes for genotype imputation. Nat Genet 2016;48:1279-83.
    • (2016) Nat Genet , vol.48 , pp. 1279-1283
    • McCarthy, S.1    Das, S.2    Kretzschmar, W.3
  • 22
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in metaanalysis of genome-wide association studies
    • Han B, Eskin E. Random-effects model aimed at discovering associations in metaanalysis of genome-wide association studies. Am J Hum Genet 2011;88:586-98.
    • (2011) Am J Hum Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 23
    • 84862832570 scopus 로고    scopus 로고
    • Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
    • Yang J, Ferreira T, Morris AP, et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet 2012;44:369-75.
    • (2012) Nat Genet , vol.44 , pp. 369-375
    • Yang, J.1    Ferreira, T.2    Morris, A.P.3
  • 24
    • 78650856517 scopus 로고    scopus 로고
    • GCTA: A tool for genome-wide complex trait analysis
    • Yang J, Lee SH, Goddard ME, et al. GCTA: A tool for genome-wide complex trait analysis. Am J Hum Genet 2011;88:76-82.
    • (2011) Am J Hum Genet , vol.88 , pp. 76-82
    • Yang, J.1    Lee, S.H.2    Goddard, M.E.3
  • 25
    • 61449107734 scopus 로고    scopus 로고
    • SNPnexus: A web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms
    • C helala C, Khan A, Lemoine NR. SNPnexus: A web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms. Bioinformatics 2009;25:655-61.
    • (2009) Bioinformatics , vol.25 , pp. 655-661
    • Chelala, C.1    Khan, A.2    Lemoine, N.R.3
  • 26
    • 75249104228 scopus 로고    scopus 로고
    • Phenopedia and Genopedia: Disease-centered and gene-centered views of the evolving knowledge of human genetic associations
    • Yu W, Clyne M, Khoury MJ, et al. Phenopedia and Genopedia: Disease-centered and gene-centered views of the evolving knowledge of human genetic associations. Bioinformatics 2010;26:145-6.
    • (2010) Bioinformatics , vol.26 , pp. 145-146
    • Yu, W.1    Clyne, M.2    Khoury, M.J.3
  • 28
    • 84976873328 scopus 로고    scopus 로고
    • HaploReg v4: Systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease
    • Ward LD, Kellis M. HaploReg v4: Systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease. Nucleic Acids Res 2016;44(D1):D877-D881.
    • (2016) Nucleic Acids Res , vol.44 , Issue.101 , pp. D877-D881
    • Ward, L.D.1    Kellis, M.2
  • 29
    • 84929001104 scopus 로고    scopus 로고
    • Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • GTEx Consortium
    • GTEx Consortium. Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science 2015;348:648-60.
    • (2015) Science , vol.348 , pp. 648-660
  • 30
    • 84983338572 scopus 로고    scopus 로고
    • CHiCP: A web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets
    • S chofield EC, Carver T, Achuthan P, et al. CHiCP: A web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets. Bioinformatics 2016;32:2511-3.
    • (2016) Bioinformatics , vol.32 , pp. 2511-2513
    • EC Chofield, S.1    Carver, T.2    Achuthan, P.3
  • 31
    • 84941051170 scopus 로고    scopus 로고
    • STRING v10: Protein-protein interaction networks, integrated over the tree of life
    • S zklarczyk D, Franceschini A, Wyder S, et al. STRING v10: Protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res 2015;43(Database issue):D447-D452.
    • (2015) Nucleic Acids Res , vol.43 , pp. D447-D452
    • D Zklarczyk, S.1    Franceschini, A.2    Wyder, S.3
  • 32
    • 85016064721 scopus 로고    scopus 로고
    • Open targets: A platform for therapeutic target identification and validation
    • Koscielny G, An P, Carvalho-Silva D, et al. Open targets: A platform for therapeutic target identification and validation. Nucleic Acids Res 2017;45(D1):D985-D994.
    • (2017) Nucleic Acids Res , vol.45 , Issue.101 , pp. D985-D994
    • Koscielny, G.1    An, P.2    Carvalho-Silva, D.3
  • 33
    • 79953208931 scopus 로고    scopus 로고
    • Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis
    • Mells GF, Floyd JA, Morley KI, et al. Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet 2011;43:329-32.
    • (2011) Nat Genet , vol.43 , pp. 329-332
    • Mells, G.F.1    Floyd, J.A.2    Morley, K.I.3
  • 34
    • 84942244702 scopus 로고    scopus 로고
    • International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
    • C ordell HJ, Han Y, Mells GF, et al. International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. Nat Commun 2015;6:8019.
    • (2015) Nat Commun , vol.6 , pp. 8019
    • Cordell, H.J.1    Han, Y.2    Mells, G.F.3
  • 35
    • 84896394396 scopus 로고    scopus 로고
    • Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation
    • Senapati S, Singh S, Das M, et al. Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation. Pharmacogenet Genomics 2014;24:211-9.
    • (2014) Pharmacogenet Genomics , vol.24 , pp. 211-219
    • Senapati, S.1    Singh, S.2    Das, M.3
  • 36
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • Dustin ML, Cooper JA. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling. Nat Immunol 2000;1:23-9.
    • (2000) Nat Immunol , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 37
    • 84960812388 scopus 로고    scopus 로고
    • A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
    • de Vries PS, Chasman DI, Sabater-Lleal M, et al. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Hum Mol Genet 2016;25:358-70.
    • (2016) Hum Mol Genet , vol.25 , pp. 358-370
    • De Vries, P.S.1    Chasman, D.I.2    Sabater-Lleal, M.3
  • 38
    • 84859715302 scopus 로고    scopus 로고
    • Fibrinogen as a key regulator of inflammation in disease
    • Davalos D, Akassoglou K. Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol 2012;34:43-62.
    • (2012) Semin Immunopathol , vol.34 , pp. 43-62
    • Davalos, D.1    Akassoglou, K.2
  • 39
    • 84988713790 scopus 로고    scopus 로고
    • Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
    • Iotchkova V, Huang J, Morris JA, et al. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nat Genet 2016;48:1303-12.
    • (2016) Nat Genet , vol.48 , pp. 1303-1312
    • Iotchkova, V.1    Huang, J.2    Morris, J.A.3
  • 40
    • 85010392496 scopus 로고    scopus 로고
    • The histone modification code in the pathogenesis of autoimmune dis Diseases
    • A raki Y, Mimura T. The histone modification code in the pathogenesis of autoimmune dis Diseases. Mediators Inflamm 2017;2017:12.
    • (2017) Mediators Inflamm , vol.2017 , pp. 12
    • Y Raki, A.1    Mimura, T.2
  • 41
    • 84938292742 scopus 로고    scopus 로고
    • The support of human genetic evidence for approved drug indications
    • Nelson MR, Tipney H, Painter JL, et al. The support of human genetic evidence for approved drug indications. Nat Genet 2015;47:856-60.
    • (2015) Nat Genet , vol.47 , pp. 856-860
    • Nelson, M.R.1    Tipney, H.2    Painter, J.L.3
  • 42
    • 84884227097 scopus 로고    scopus 로고
    • Type I IFNs downregulate myeloid cell IFN-receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription
    • Kearney SJ, Delgado C, Eshleman EM, et al. Type I IFNs downregulate myeloid cell IFN- receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. J Immunol 2013;191:3384-92.
    • (2013) J Immunol , vol.191 , pp. 3384-3392
    • Kearney, S.J.1    Delgado, C.2    Eshleman, E.M.3
  • 43
    • 84946478272 scopus 로고    scopus 로고
    • Immunogenetics of systemic sclerosis: Defining heritability, functional variants and shared-autoimmunity pathways
    • Bossini-Castillo L, López-Isac E, Martín J. Immunogenetics of systemic sclerosis: Defining heritability, functional variants and shared-autoimmunity pathways. J Autoimmun 2015;64:53-65.
    • (2015) J Autoimmun , vol.64 , pp. 53-65
    • Bossini-Castillo, L.1    López-Isac, E.2    Martín, J.3
  • 44
    • 84898413247 scopus 로고    scopus 로고
    • Type I interferon signature in systemic lupus erythematosus
    • Bezalel S, Guri KM, Elbirt D, et al. Type I interferon signature in systemic lupus erythematosus. Isr Med Assoc J 2014;16:246-9.
    • (2014) Isr Med Assoc J , vol.16 , pp. 246-249
    • Bezalel, S.1    Guri, K.M.2    Elbirt, D.3
  • 45
    • 84928728998 scopus 로고    scopus 로고
    • Interferon gene expression signature in rheumatoid arthritis neutrophils correlates with a good response to TNFi therapy
    • Wright HL, Thomas HB, Moots RJ, et al. Interferon gene expression signature in rheumatoid arthritis neutrophils correlates with a good response to TNFi therapy. Rheumatology 2015;54:188-93.
    • (2015) Rheumatology , vol.54 , pp. 188-193
    • Wright, H.L.1    Thomas, H.B.2    Moots, R.J.3
  • 46
    • 77951464574 scopus 로고    scopus 로고
    • The type I interferon system in idiopathic inflammatory myopathies
    • L undberg IE, Helmers SB. The type I interferon system in idiopathic inflammatory myopathies. Autoimmunity 2010;43:239-43.
    • (2010) Autoimmunity , vol.43 , pp. 239-243
    • IE Undberg, L.1    Helmers, S.B.2
  • 47
    • 84864475765 scopus 로고    scopus 로고
    • Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor
    • van Baal J, de Widt J, Divecha N, et al. Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor. Int J Biochem Cell Biol 2012;44:1791-9.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1791-1799
    • Van Baal, J.1    De Widt, J.2    Divecha, N.3
  • 48
    • 79953852372 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosisassociated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: A case-control study
    • O verbeek MJ, Boonstra A, Voskuyl AE, et al. Platelet-derived growth factor receptor- and epidermal growth factor receptor in pulmonary vasculature of systemic sclerosisassociated pulmonary arterial hypertension versus idiopathic pulmonary arterial hypertension and pulmonary veno-occlusive disease: A case-control study. Arthritis Res Ther 2011;13:R61.
    • (2011) Arthritis Res Ther , vol.13 , pp. R61
    • MJ Verbeek, O.1    Boonstra, A.2    Voskuyl, A.E.3
  • 49
    • 84887116043 scopus 로고    scopus 로고
    • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome
    • L essard CJ, Li H, Adrianto I, et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome. Nat Genet 2013;45:1284-92.
    • (2013) Nat Genet , vol.45 , pp. 1284-1292
    • CJ Essard, L.1    Li, H.2    Adrianto, I.3
  • 50
    • 79954426066 scopus 로고    scopus 로고
    • A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation
    • Paul P, van den Hoorn T, Jongsma ML, et al. A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell 2011;145:268-83.
    • (2011) Cell , vol.145 , pp. 268-283
    • Paul, P.1    Van Den Hoorn, T.2    Jongsma, M.L.3
  • 51
    • 84867164377 scopus 로고    scopus 로고
    • C-reactive protein, fibrinogen, and cardiovascular disease prediction
    • E merging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E, et al. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 2012;367:1310-20.
    • (2012) N Engl J Med , vol.367 , pp. 1310-1320
    • Kaptoge, S.1    Di Angelantonio, E.2
  • 52
    • 35349030411 scopus 로고    scopus 로고
    • Fibrosis in connective tissue disease: The role of the myofibroblast and fibroblast-epithelial cell interactions
    • Suppl 2
    • Krieg T, Abraham D, Lafyatis R. Fibrosis in connective tissue disease: The role of the myofibroblast and fibroblast-epithelial cell interactions. Arthritis Res Ther 2007;9 Suppl 2(Suppl 2):S4.
    • (2007) Arthritis Res Ther , vol.9 , pp. S4
    • Krieg, T.1    Abraham, D.2    Lafyatis, R.3
  • 53
    • 84992490317 scopus 로고    scopus 로고
    • Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers
    • L ópez-Mejías R, Castañeda S, González-Juanatey C, et al. Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers. Autoimmun Rev 2016;15:1013-30.
    • (2016) Autoimmun Rev , vol.15 , pp. 1013-1030
    • R Ópez-Mejías, L.1    Castañeda, S.2    González-Juanatey, C.3
  • 54
    • 85042356174 scopus 로고    scopus 로고
    • Cardiovascular and pulmonary manifestations of systemic lupus erythematosus
    • Tselios K, Urowitz MB. Cardiovascular and pulmonary manifestations of systemic lupus erythematosus. Curr Rheumatol Rev 2017;13:206-18.
    • (2017) Curr Rheumatol Rev , vol.13 , pp. 206-218
    • Tselios, K.1    Urowitz, M.B.2
  • 55
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • L amouille S, Xu J, Derynck R. Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 2014;15:178-96.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • S Amouille, L.1    Xu, J.2    Derynck, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.