메뉴 건너뛰기




Volumn 14, Issue , 2018, Pages 2367-2378

PTSD patients show increasing cytokine levels during treatment despite reduced psychological distress

Author keywords

Cytokines; Immune activation; Inflammation; PTSD; Trauma

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR;

EID: 85057529932     PISSN: None     EISSN: 11782021     Source Type: Journal    
DOI: 10.2147/NDT.S173659     Document Type: Article
Times cited : (33)

References (36)
  • 2
    • 84901433013 scopus 로고    scopus 로고
    • Neuroimmunoendocrine interactions in post-traumatic stress disorder: Focus on long-term implications of childhood maltreatment
    • Wieck A, Grassi-Oliveira R, Hartmann do Prado C, Teixeira AL, Bauer ME. Neuroimmunoendocrine interactions in post-traumatic stress disorder: focus on long-term implications of childhood maltreatment. Neuroim-munomodulation. 2014;21(2–3):145–151.
    • (2014) Neuroim-Munomodulation , vol.21 , Issue.2-3 , pp. 145-151
    • Wieck, A.1    Grassi-Oliveira, R.2    Hartmann Do Prado, C.3    Teixeira, A.L.4    Bauer, M.E.5
  • 3
    • 85017002844 scopus 로고    scopus 로고
    • Peripheral cytokine and chemokine alterations in depression: A meta-analysis of 82 studies
    • Köhler CA, Freitas TH, Maes M, et al. Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies. Acta Psychiatr Scand. 2017;135(5):373–387.
    • (2017) Acta Psychiatr Scand , vol.135 , Issue.5 , pp. 373-387
    • Köhler, C.A.1    Freitas, T.H.2    Maes, M.3
  • 4
    • 85020741434 scopus 로고    scopus 로고
    • Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis
    • Köhler CA, Freitas TH, Stubbs B, et al. Peripheral Alterations in Cytokine and Chemokine Levels After Antidepressant Drug Treatment for Major Depressive Disorder: Systematic Review and Meta-Analysis. Mol Neurobiol. 2018;55(5):4195–4206.
    • (2018) Mol Neurobiol , vol.55 , Issue.5 , pp. 4195-4206
    • Köhler, C.A.1    Freitas, T.H.2    Stubbs, B.3
  • 5
    • 85032068919 scopus 로고    scopus 로고
    • PTSD, a Disorder with an Immunological Component
    • Wang Z, Young MR. PTSD, a Disorder with an Immunological Component. Front Immunol. 2016;7:219.
    • (2016) Front Immunol , vol.7 , pp. 219
    • Wang, Z.1    Young, M.R.2
  • 6
    • 84951017668 scopus 로고    scopus 로고
    • Inflammatory markers in post-traumatic stress disorder: A systematic review, meta-analysis, and meta-regression
    • Passos IC, Vasconcelos-Moreno MP, Costa LG, et al. Inflammatory markers in post-traumatic stress disorder: a systematic review, meta-analysis, and meta-regression. Lancet Psychiatry. 2015;2(11): 1002–1012.
    • (2015) Lancet Psychiatry , vol.2 , Issue.11 , pp. 1002-1012
    • Passos, I.C.1    Vasconcelos-Moreno, M.P.2    Costa, L.G.3
  • 7
    • 84973636666 scopus 로고    scopus 로고
    • Recovery from major depressive disorder episode after nonpharmacological treatment is associated with normalized cytokine levels
    • Dahl J, Ormstad H, Aass HC, Sandvik L, Malt UF, Andreassen OA. Recovery from major depressive disorder episode after nonpharmacological treatment is associated with normalized cytokine levels. Acta Psychiatr Scand. 2016;134(1):40–47.
    • (2016) Acta Psychiatr Scand , vol.134 , Issue.1 , pp. 40-47
    • Dahl, J.1    Ormstad, H.2    Aass, H.C.3    Sandvik, L.4    Malt, U.F.5    Andreassen, O.A.6
  • 8
    • 84875244813 scopus 로고    scopus 로고
    • Women in recovery from PTSD have similar inflammation and quality of life as non-traumatized controls
    • Gill JM, Saligan L, Lee H, Rotolo S, Szanton S. Women in recovery from PTSD have similar inflammation and quality of life as non-traumatized controls. J Psychosom Res. 2013;74(4):301–306.
    • (2013) J Psychosom Res , vol.74 , Issue.4 , pp. 301-306
    • Gill, J.M.1    Saligan, L.2    Lee, H.3    Rotolo, S.4    Szanton, S.5
  • 9
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurode-generative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression
    • Maes M, Yirmyia R, Noraberg J, et al. The inflammatory & neurode-generative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression. Metab Brain Dis. 2009; 24(1):27–53.
    • (2009) Metab Brain Dis , vol.24 , Issue.1 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3
  • 10
    • 85047931333 scopus 로고    scopus 로고
    • A Systematic Review of Interleukin-1β in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies
    • Waheed A, Dalton B, Wesemann U, Ibrahim MAA, Himmerich H. A Systematic Review of Interleukin-1β in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies. J Interferon Cytokine Res. 2018;38(1):1–11.
    • (2018) J Interferon Cytokine Res , vol.38 , Issue.1 , pp. 1-11
    • Waheed, A.1    Dalton, B.2    Wesemann, U.3    Ibrahim, M.A.A.4    Himmerich, H.5
  • 12
    • 84867582069 scopus 로고    scopus 로고
    • Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study
    • Abbasi SH, Hosseini F, Modabbernia A, Ashrafi M, Akhondzadeh S. Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: randomized double-blind placebo-controlled study. J Affect Disord. 2012;141(2–3):308–314.
    • (2012) J Affect Disord , vol.141 , Issue.2-3 , pp. 308-314
    • Abbasi, S.H.1    Hosseini, F.2    Modabbernia, A.3    Ashrafi, M.4    Akhondzadeh, S.5
  • 13
    • 79959343388 scopus 로고    scopus 로고
    • Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans
    • Warner-Schmidt JL, Vanover KE, Chen EY, Marshall JJ, Greengard P. Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans. Proc Natl Acad Sci U S A. 2011;108(22):9262–9267.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.22 , pp. 9262-9267
    • Warner-Schmidt, J.L.1    Vanover, K.E.2    Chen, E.Y.3    Marshall, J.J.4    Greengard, P.5
  • 14
    • 85045210568 scopus 로고    scopus 로고
    • The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment
    • Toft H, Neupane SP, Bramness JG, Tilden T, Wampold BE, Lien L. The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment. BMC Psychiatry. 2018;18(1):95.
    • (2018) BMC Psychiatry , vol.18 , Issue.1 , pp. 95
    • Toft, H.1    Neupane, S.P.2    Bramness, J.G.3    Tilden, T.4    Wampold, B.E.5    Lien, L.6
  • 15
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • Sheehan DV, Lecrubier Y, Sheehan KH. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl 20):34–57.
    • (1998) J Clin Psychiatry , vol.59 , pp. 34-57
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3
  • 17
    • 84898599060 scopus 로고    scopus 로고
    • Psychometric validation of the Hopkins Symptom Checklist (SCL-90) subscales for depression, anxiety, and interpersonal sensitivity
    • Bech P, Bille J, Møller SB, Hellström LC, Østergaard SD. Psychometric validation of the Hopkins Symptom Checklist (SCL-90) subscales for depression, anxiety, and interpersonal sensitivity. J Affect Disord. 2014;160:98–103.
    • (2014) J Affect Disord , vol.160 , pp. 98-103
    • Bech, P.1    Bille, J.2    Møller, S.B.3    Hellström, L.C.4    Østergaard, S.D.5
  • 18
    • 4344573247 scopus 로고    scopus 로고
    • Is SCL-90R helpful for the clinician in assessing DSM-IV symptom disorders?
    • Pedersen G, Karterud S. Is SCL-90R helpful for the clinician in assessing DSM-IV symptom disorders? Acta Psychiatr Scand. 2004; 110(3):215–224.
    • (2004) Acta Psychiatr Scand , vol.110 , Issue.3 , pp. 215-224
    • Pedersen, G.1    Karterud, S.2
  • 20
    • 84936853890 scopus 로고
    • A test of Missing Completely at Random for Multivariate Data with Missing Values
    • Little RJA. A test of Missing Completely at Random for Multivariate Data with Missing Values. J Am Stat Assoc. 1988;83(404):1198–1202.
    • (1988) J am Stat Assoc , vol.83 , Issue.404 , pp. 1198-1202
    • Little, R.J.A.1
  • 21
    • 84927169281 scopus 로고    scopus 로고
    • Circulating levels of hormones, lipids, and immune mediators in post-traumatic stress disorder – a 3-month follow-up study
    • Jergović M, Bendelja K, Savić Mlakar A, et al. Circulating levels of hormones, lipids, and immune mediators in post-traumatic stress disorder – a 3-month follow-up study. Front Psychiatry. 2015;14;6:49.
    • (2015) Front Psychiatry , vol.14 , Issue.6 , pp. 49
    • Jergović, M.1    Bendelja, K.2    Savić Mlakar, A.3
  • 22
    • 3042520734 scopus 로고    scopus 로고
    • Neuroimmune and cortisol changes in selective serotonin reuptake inhibitor and placebo treatment of chronic posttraumatic stress disorder
    • Tucker P, Ruwe WD, Masters B, et al. Neuroimmune and cortisol changes in selective serotonin reuptake inhibitor and placebo treatment of chronic posttraumatic stress disorder. Biol Psychiatry. 2004; 56(2):121–128.
    • (2004) Biol Psychiatry , vol.56 , Issue.2 , pp. 121-128
    • Tucker, P.1    Ruwe, W.D.2    Masters, B.3
  • 23
    • 84989927214 scopus 로고    scopus 로고
    • Serum concentrations of TNF-α and its soluble receptors during psychotherapy in German soldiers suffering from combat-related PTSD
    • Himmerich H, Willmund GD, Zimmermann P, et al. Serum concentrations of TNF-α and its soluble receptors during psychotherapy in German soldiers suffering from combat-related PTSD. Psychiatr Danub. 2016;28(3):293–298.
    • (2016) Psychiatr Danub , vol.28 , Issue.3 , pp. 293-298
    • Himmerich, H.1    Willmund, G.D.2    Zimmermann, P.3
  • 24
    • 61849166110 scopus 로고    scopus 로고
    • Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD
    • Gill J, Vythilingam M, Page GG. Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD. J Trauma Stress. 2008;21(6):530–539.
    • (2008) J Trauma Stress , vol.21 , Issue.6 , pp. 530-539
    • Gill, J.1    Vythilingam, M.2    Page, G.G.3
  • 25
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: The role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
    • Raison CL, Miller AH. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry. 2003;160(9):1554–1565.
    • (2003) Am J Psychiatry , vol.160 , Issue.9 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 26
    • 85037099902 scopus 로고    scopus 로고
    • A Systematic Review of Tumor Necrosis Factor-α in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies
    • Hussein S, Dalton B, Willmund GD, Ibrahim MAA, Himmerich H. A Systematic Review of Tumor Necrosis Factor-α in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies. Psychiatr Danub. 2017;29(4):407–420.
    • (2017) Psychiatr Danub , vol.29 , Issue.4 , pp. 407-420
    • Hussein, S.1    Dalton, B.2    Willmund, G.D.3    Ibrahim, M.A.A.4    Himmerich, H.5
  • 27
    • 34247547482 scopus 로고    scopus 로고
    • Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder
    • von Känel R, Hepp U, Kraemer B, et al. Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. J Psychiatr Res. 2007;41(9):744–752.
    • (2007) J Psychiatr Res , vol.41 , Issue.9 , pp. 744-752
    • von Känel, R.1    Hepp, U.2    Kraemer, B.3
  • 28
    • 85033570997 scopus 로고    scopus 로고
    • Posttraumatic Stress Disorder: An Immunological Disorder?
    • Wang Z, Caughron B, Young MRI. Posttraumatic Stress Disorder: An Immunological Disorder? Front Psychiatry. 2017;8:222.
    • (2017) Front Psychiatry , vol.8 , pp. 222
    • Wang, Z.1    Caughron, B.2    Young, M.R.I.3
  • 29
    • 85044213318 scopus 로고    scopus 로고
    • Oxidative Stress, Inflammation, and Neuroprogression in Chronic PTSD
    • Miller MW, Lin AP, Wolf EJ, Miller DR. Oxidative Stress, Inflammation, and Neuroprogression in Chronic PTSD. Harv Rev Psychiatry. 2018;26(2):57–69.
    • (2018) Harv Rev Psychiatry , vol.26 , Issue.2 , pp. 57-69
    • Miller, M.W.1    Lin, A.P.2    Wolf, E.J.3    Miller, D.R.4
  • 30
    • 84863358869 scopus 로고    scopus 로고
    • Study on serum cytokine levels in posttraumatic stress disorder patients
    • Guo M, Liu T, Guo JC, Jiang XL, Chen F, Gao YS. Study on serum cytokine levels in posttraumatic stress disorder patients. Asian Pac J Trop Med. 2012;5(4):323–325.
    • (2012) Asian Pac J Trop Med , vol.5 , Issue.4 , pp. 323-325
    • Guo, M.1    Liu, T.2    Guo, J.C.3    Jiang, X.L.4    Chen, F.5    Gao, Y.S.6
  • 31
    • 84872914326 scopus 로고    scopus 로고
    • Posttraumatic stress disorder is associated with an enhanced spontaneous production of proinflammatory cytokines by peripheral blood mononuclear cells
    • Gola H, Engler H, Sommershof A, et al. Posttraumatic stress disorder is associated with an enhanced spontaneous production of proinflammatory cytokines by peripheral blood mononuclear cells. BMC Psychiatry. 2013;13(1):1.
    • (2013) BMC Psychiatry , vol.13 , Issue.1 , pp. 1
    • Gola, H.1    Engler, H.2    Sommershof, A.3
  • 32
    • 84896490306 scopus 로고    scopus 로고
    • Cytokines plasma levels during antidepressant treatment with sertraline and transcranial direct current stimulation (TDCS): Results from a factorial, randomized, controlled trial
    • Brunoni AR, Machado-Vieira R, Zarate CA, et al. Cytokines plasma levels during antidepressant treatment with sertraline and transcranial direct current stimulation (tDCS): results from a factorial, randomized, controlled trial. Psychopharmacology. 2014;231(7):1315–1323.
    • (2014) Psychopharmacology , vol.231 , Issue.7 , pp. 1315-1323
    • Brunoni, A.R.1    Machado-Vieira, R.2    Zarate, C.A.3
  • 34
    • 79952337627 scopus 로고    scopus 로고
    • Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production
    • Dixit VD, Yang H, Sayeed KS, et al. Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production. J Inflamm. 2011;8(1):1.
    • (2011) J Inflamm , vol.8 , Issue.1 , pp. 1
    • Dixit, V.D.1    Yang, H.2    Sayeed, K.S.3
  • 35
    • 84902328863 scopus 로고    scopus 로고
    • The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: An exploratory study
    • Pisetsky DS, Trace SE, Brownley KA, et al. The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study. Cytokine. 2014;69(1): 110–115.
    • (2014) Cytokine , vol.69 , Issue.1 , pp. 110-115
    • Pisetsky, D.S.1    Trace, S.E.2    Brownley, K.A.3
  • 36
    • 84903642413 scopus 로고    scopus 로고
    • Smoking enhances the proinflammatory effects of nucleotides on cytokine release from human lung
    • Belchamber K, Hall DA, Hourani SM. Smoking enhances the proinflammatory effects of nucleotides on cytokine release from human lung. PLoS One. 2014;9(6):e99711.
    • (2014) Plos One , vol.9 , Issue.6
    • Belchamber, K.1    Hall, D.A.2    Hourani, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.