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Volumn 3, Issue 1, 2017, Pages

Combinatorial biosynthesis of novel multi-hydroxy carotenoids in the red yeast Xanthophyllomyces dendrorhous

Author keywords

4,4 dihydroxy nostoxanthin; 4,4 diketo nostoxanthin; Carotenoid biosynthesis; Genetic engineering; HPLC separation; MS MS spectra; Xanthophyllomyces dendrorhous

Indexed keywords


EID: 85056773221     PISSN: None     EISSN: 2309608X     Source Type: Journal    
DOI: 10.3390/jof3010009     Document Type: Article
Times cited : (10)

References (32)
  • 1
    • 0000180004 scopus 로고
    • ′R)-Astaxanthin from the yeast Phaffia rhodozyma
    • ′R)-Astaxanthin from the yeast Phaffia rhodozyma. Phytochemistry 1976, 15, 1009–1011. [CrossRef]
    • (1976) Phytochemistry , vol.15 , pp. 1009-1011
    • Andrewes, A.G.1    Starr, M.P.2
  • 2
    • 4143116359 scopus 로고    scopus 로고
    • The Mycota X; industrial application; Osiewacz, H.D., Ed.; Springer: Berlin, Germany
    • Sandmann, G.; Misawa, N. Fungal carotenoids. In The Mycota X; industrial application; Osiewacz, H.D., Ed.; Springer: Berlin, Germany, 2002; pp. 247–262.
    • (2002) Fungal Carotenoids , pp. 247-262
    • Sandmann, G.1    Misawa, N.2
  • 3
    • 78149359483 scopus 로고    scopus 로고
    • Xanthophyllomyces dendrorhous for the industrial production of astaxanthin
    • Rodriguez-Saiz, M.; de la Fuente, J.L.; Barredo, J.L. Xanthophyllomyces dendrorhous for the industrial production of astaxanthin. Appl. Microbiol. Biotechnol. 2010, 88, 645–658. [CrossRef] [PubMed]
    • (2010) Appl. Microbiol. Biotechnol. , vol.88 , pp. 645-658
    • Rodriguez-Saiz, M.1    de la Fuente, J.L.2    Barredo, J.L.3
  • 5
    • 84930196882 scopus 로고    scopus 로고
    • Carotenoids of biotechnological importance
    • Schrader, J., Bohlmann, J., Eds.; Springer: Berlin/Heidelberg, Germany
    • Sandmann, G. Carotenoids of biotechnological importance. In Biotechnology of Isoprenoids, Advances in Biochemical Engineering/Biotechnology; Schrader, J., Bohlmann, J., Eds.; Springer: Berlin/Heidelberg, Germany, 2014; Volume 148, pp. 449–467.
    • (2014) Biotechnology of Isoprenoids, Advances in Biochemical Engineering/Biotechnology , vol.148 , pp. 449-467
    • Sandmann, G.1
  • 6
    • 32444435890 scopus 로고    scopus 로고
    • Xanthophylls in fungi: Metabolic engineering of the astaxanthin biosynthetic pathway in Xantophyllomyces. dendrorhous
    • Humana: Totowa, NJ, USA
    • Visser, H.; Sandmann, G.; Verdoes, J.C. Xanthophylls in fungi: metabolic engineering of the astaxanthin biosynthetic pathway in Xantophyllomyces. dendrorhous. In Methods in Biotechnology: Microbial Processes and Products; Humana: Totowa, NJ, USA, 2005.
    • Methods in Biotechnology: Microbial Processes and Products , pp. 2005
    • Visser, H.1    Sandmann, G.2    Verdoes, J.C.3
  • 7
    • 84891857645 scopus 로고    scopus 로고
    • Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant
    • Gassel, S.; Breitenbach, J.; Sandmann, G. Genetic engineering of the complete carotenoid pathway towards enhanced astaxanthin formation in Xanthophyllomyces dendrorhous starting from a high-yield mutant. Appl. Microbiol. Biotechnol. 2014, 98, 345–350. [CrossRef] [PubMed]
    • (2014) Appl. Microbiol. Biotechnol. , vol.98 , pp. 345-350
    • Gassel, S.1    Breitenbach, J.2    Sandmann, G.3
  • 9
    • 84926609326 scopus 로고    scopus 로고
    • The genome of the basal agaricomycete Xanthophyllomyces dendrorhous provides insights into the organization of its acetyl-CoA derived pathways and the evolution of agaricomycotina
    • Sharma, R.; Gassel, S.; Steiger, S.; Xia, X.; Bauer, R.; Sandmann, G.; Thines, M. The genome of the basal agaricomycete Xanthophyllomyces dendrorhous provides insights into the organization of its acetyl-CoA derived pathways and the evolution of agaricomycotina. BMC Genom. 2015, 16, 233. [CrossRef] [PubMed]
    • (2015) BMC Genom , vol.16 , pp. 233
    • Sharma, R.1    Gassel, S.2    Steiger, S.3    Xia, X.4    Bauer, R.5    Sandmann, G.6    Thines, M.7
  • 11
    • 32444444375 scopus 로고    scopus 로고
    • Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a β-carotene 3-hydroxylase/4-ketolase
    • Ojima, K.; Breitenbach, J.; Visser, H.; Setoguchi, Y.; Tabata, K.; Hoshino, T.; van den Berg, J.; Sandmann, G. Cloning of the astaxanthin synthase gene from Xanthophyllomyces dendrorhous (Phaffia rhodozyma) and its assignment as a β-carotene 3-hydroxylase/4-ketolase. Mol. Genet. Genom. 2006, 275, 148–158. [CrossRef] [PubMed]
    • (2006) Mol. Genet. Genom. , vol.275 , pp. 148-158
    • Ojima, K.1    Breitenbach, J.2    Visser, H.3    Setoguchi, Y.4    Tabata, K.5    Hoshino, T.6    van den Berg, J.7    Sandmann, G.8
  • 12
    • 84982166189 scopus 로고    scopus 로고
    • Engineering of the carotenoid pathway in Xanthophyllomyces dendrorhous leading to the synthesis of zeaxanthin
    • Pollmann, H.; Breitenbach, J.; Sandmann, G. Engineering of the carotenoid pathway in Xanthophyllomyces dendrorhous leading to the synthesis of zeaxanthin. Appl. Microbiol. Biotechnol. 2016, 101, 103–111. [CrossRef] [PubMed]
    • (2016) Appl. Microbiol. Biotechnol. , vol.101 , pp. 103-111
    • Pollmann, H.1    Breitenbach, J.2    Sandmann, G.3
  • 13
    • 0032883216 scopus 로고    scopus 로고
    • Metabolic engineering of the terpenoid biosynthetic pathway of Escherichia coli for production of the carotenoids β-carotene and zeaxanthin
    • Albrecht, M.; Misawa, N.; Sandmann, G. Metabolic engineering of the terpenoid biosynthetic pathway of Escherichia coli for production of the carotenoids β-carotene and zeaxanthin. Biotechnol. Lett. 1999, 21, 791–795. [CrossRef]
    • (1999) Biotechnol. Lett. , vol.21 , pp. 791-795
    • Albrecht, M.1    Misawa, N.2    Sandmann, G.3
  • 14
    • 79954627687 scopus 로고    scopus 로고
    • Production of caloxanthin-β-D-glucoside, zeaxanthin 3,3-β-D-diglucoside, and nostoxanthin in a recombinant Escherichia coli expressing system harbouring seven carotenoid biosynthesis genes, including crtX and crtG
    • Osawa, A.; Harada, H.; Choi, S.-K.; Misawa, N.; Shindo, K. Production of caloxanthin-β-D-glucoside, zeaxanthin 3,3-β-D-diglucoside, and nostoxanthin in a recombinant Escherichia coli expressing system harbouring seven carotenoid biosynthesis genes, including crtX and crtG. Phytochemistry 2011, 72, 711–716. [CrossRef] [PubMed]
    • (2011) Phytochemistry , vol.72 , pp. 711-716
    • Osawa, A.1    Harada, H.2    Choi, S.-K.3    Misawa, N.4    Shindo, K.5
  • 15
    • 0033876920 scopus 로고    scopus 로고
    • Novel hydroxycarotenoids with improved antioxidative properties produced by gene combination in Escherichia coli
    • Albrecht, M.; Takaichi, S.; Steiger, S.; Wang, Z.Y.; Sandmann, G. Novel hydroxycarotenoids with improved antioxidative properties produced by gene combination in Escherichia coli. Nat. Biotechnol. 2000, 18, 843–846. [CrossRef] [PubMed]
    • (2000) Nat. Biotechnol. , vol.18 , pp. 843-846
    • Albrecht, M.1    Takaichi, S.2    Steiger, S.3    Wang, Z.Y.4    Sandmann, G.5
  • 17
    • 0030996054 scopus 로고    scopus 로고
    • XcmI-Containing vector for direct cloning of PCR products
    • Borovkov, A.Y.; Rivkin, M.I. XcmI-Containing vector for direct cloning of PCR products. BioTechniques 1997, 22, 812–814.
    • (1997) Biotechniques , vol.22 , pp. 812-814
    • Borovkov, A.Y.1    Rivkin, M.I.2
  • 18
    • 0028817748 scopus 로고
    • Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level
    • Misawa, N.; Satomi, Y.; Kondo, K.; Yokoyama, A.; Kajiwara, S.; Saito, T.; Ohtani, T.; Miki, W. Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level. J. Bacteriol. 1995, 177, 6575–6584. [CrossRef] [PubMed]
    • (1995) J. Bacteriol. , vol.177 , pp. 6575-6584
    • Misawa, N.1    Satomi, Y.2    Kondo, K.3    Yokoyama, A.4    Kajiwara, S.5    Saito, T.6    Ohtani, T.7    Miki, W.8
  • 19
    • 79960220136 scopus 로고    scopus 로고
    • Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis
    • Zhong, Y.J.; Huang, J.C.; Liu, J.; Li, Y.; Jiang, Y.; Xu, Z.F.; Sandmann, G.; Chen, F. Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis. J. Exp. Bot. 2011, 62, 3659–3669. [CrossRef] [PubMed]
    • (2011) J. Exp. Bot. , vol.62 , pp. 3659-3669
    • Zhong, Y.J.1    Huang, J.C.2    Liu, J.3    Li, Y.4    Jiang, Y.5    Xu, Z.F.6    Sandmann, G.7    Chen, F.8
  • 20
    • 84871888089 scopus 로고    scopus 로고
    • Catalytic properties and reaction mechanism of the CrtO carotenoid ketolase from the cyanobacterium Synechocystis sp. PCC 6803
    • Breitenbach, J.; Gerjets, T.; Sandmann, G. Catalytic properties and reaction mechanism of the CrtO carotenoid ketolase from the cyanobacterium Synechocystis sp. PCC 6803. Arch. Biochem. Biophys. 2013, 529, 86–91. [CrossRef] [PubMed]
    • (2013) Arch. Biochem. Biophys. , vol.529 , pp. 86-91
    • Breitenbach, J.1    Gerjets, T.2    Sandmann, G.3
  • 21
    • 33749872408 scopus 로고    scopus 로고
    • Characterization of bacterial β-carotene 3,3'-hydroxylases, CrtZ, and P450 in astaxanthin biosynthetic pathway and adonirubin production by gene combination in Escherichia coli
    • Choi, S.K.; Matsuda, S.; Hoshino, T.; Peng, X.; Misawa, N. Characterization of bacterial β-carotene 3,3'-hydroxylases, CrtZ, and P450 in astaxanthin biosynthetic pathway and adonirubin production by gene combination in Escherichia coli. Appl. Microbiol. Biotechnol. 2006, 72, 1238–1246. [CrossRef] [PubMed]
    • (2006) Appl. Microbiol. Biotechnol. , vol.72 , pp. 1238-1246
    • Choi, S.K.1    Matsuda, S.2    Hoshino, T.3    Peng, X.4    Misawa, N.5
  • 22
    • 0002689082 scopus 로고
    • Chemical derivatization: Microsomale tests for the presence of common functional groups in carotenoids
    • Britton, G., Liaaen-Jensen, S., Pfander, H., Eds.; Birkhäuser Verlag: Basel, Switzerland
    • Eugster, C.H. Chemical derivatization: Microsomale tests for the presence of common functional groups in carotenoids. In Carotenoid Volume 1A Isolation and Analysis; Britton, G., Liaaen-Jensen, S., Pfander, H., Eds.; Birkhäuser Verlag: Basel, Switzerland, 1995; pp. 71–80.
    • (1995) Carotenoid Volume 1A Isolation and Analysis , pp. 71-80
    • Eugster, C.H.1
  • 23
    • 84920920575 scopus 로고    scopus 로고
    • Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria Bacillus indicus and Bacillus firmus
    • Steiger, S.; Perez-Fons, L.; Cutting, S.M.; Fraser, P.D.; Sandmann, G. Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria Bacillus indicus and Bacillus firmus. Microbiology 2015, 161, 194–202. [CrossRef] [PubMed]
    • (2015) Microbiology , vol.161 , pp. 194-202
    • Steiger, S.1    Perez-Fons, L.2    Cutting, S.M.3    Fraser, P.D.4    Sandmann, G.5
  • 24
    • 84902318915 scopus 로고    scopus 로고
    • Yeast homologous recombination cloning leading to the novel peptides ambactin and xenolindicin
    • Schimming, O.; Fleischhacker, F.; Nollmann, F.I.; Bode, H.B. Yeast homologous recombination cloning leading to the novel peptides ambactin and xenolindicin. ChemBioChem 2014, 15, 1290–1294. [CrossRef] [PubMed]
    • (2014) Chembiochem , vol.15 , pp. 1290-1294
    • Schimming, O.1    Fleischhacker, F.2    Nollmann, F.I.3    Bode, H.B.4
  • 25
    • 0036901989 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of carotenoids in a heterologous host: A powerfull approach for the biosynthesis of novel structures
    • Sandmann, G. Combinatorial biosynthesis of carotenoids in a heterologous host: A powerfull approach for the biosynthesis of novel structures. ChemBioChem 2002, 3, 629–635. [CrossRef]
    • (2002) Chembiochem , vol.3 , pp. 629-635
    • Sandmann, G.1
  • 27
    • 0345033765 scopus 로고
    • Carotenoids of Anacystis nidulans, structures of caloxanthin and nostoxanthin
    • Buchecker, R.; Liaaen-Jensen, S.; Borch, G.; Siegelman, H.W. Carotenoids of Anacystis nidulans, structures of caloxanthin and nostoxanthin. Phytochemistry 1976, 15, 1015–1018. [CrossRef]
    • (1976) Phytochemistry , vol.15 , pp. 1015-1018
    • Buchecker, R.1    Liaaen-Jensen, S.2    Borch, G.3    Siegelman, H.W.4
  • 28
    • 0030068742 scopus 로고    scopus 로고
    • New trihydroxy-keto-carotenoids Isolated from an astaxanthin-producing marine bacterium
    • Yokoyama, A.; Miki, W.; Zumida, H.; Shizuri, Y. New trihydroxy-keto-carotenoids Isolated from an astaxanthin-producing marine bacterium. Biosci. Biotech. Biochem. 1996, 60, 200–203. [CrossRef] [PubMed]
    • (1996) Biosci. Biotech. Biochem. , vol.60 , pp. 200-203
    • Yokoyama, A.1    Miki, W.2    Zumida, H.3    Shizuri, Y.4
  • 29
    • 0018597254 scopus 로고
    • Carotenoids of Rhizobia. IV. Isolation and structure elucidation of the carotenoids of a mutant of Rhizobium lupine
    • Beyer, P.; Kleinig, H.; Englert, G.; Meister, W.; Noaek, K. Carotenoids of Rhizobia. IV. Isolation and structure elucidation of the carotenoids of a mutant of Rhizobium lupine. Helvetica Chim. Acta 1979, 260, 2551–2557. [CrossRef]
    • (1979) Helvetica Chim. Acta , vol.260 , pp. 2551-2557
    • Beyer, P.1    Kleinig, H.2    Englert, G.3    Meister, W.4    Noaek, K.5
  • 30
    • 23844437374 scopus 로고    scopus 로고
    • Heat-induced and light-induced isomerization of the xanthophyll pigment zeaxanthin
    • Milanowska, J.; Gruszecki, W.I. Heat-induced and light-induced isomerization of the xanthophyll pigment zeaxanthin. J. Photochem. Photobiol. 2005, 80, 178–186. [CrossRef] [PubMed]
    • (2005) J. Photochem. Photobiol. , vol.80 , pp. 178-186
    • Milanowska, J.1    Gruszecki, W.I.2
  • 31
    • 84905565957 scopus 로고    scopus 로고
    • Identification of carotenoids using mass spectrometry
    • Rivera, S.M.; Christou, P.; Canela-Garayoa, R. Identification of carotenoids using mass spectrometry. Mass Spectromet. Rev. 2014, 33, 353–372. [CrossRef] [PubMed]
    • (2014) Mass Spectromet. Rev. , vol.33 , pp. 353-372
    • Rivera, S.M.1    Christou, P.2    Canela-Garayoa, R.3
  • 32
    • 84894124115 scopus 로고    scopus 로고
    • Multiple transformation with the crtYB gene of the limiting enzyme increased carotenoid synthesis and generated novel derivatives in Xanthophyllomyces dendrorhous
    • Ledetzky, N.; Osawa, A.; Iki, K.; Pollmann, H.; Gassel, S.; Breitenbach, J.; Shindo, K.; Sandmann, G. Multiple transformation with the crtYB gene of the limiting enzyme increased carotenoid synthesis and generated novel derivatives in Xanthophyllomyces dendrorhous. Arch. Biochem. Biophys. 2014, 545, 141–147. [CrossRef] [PubMed]
    • (2014) Arch. Biochem. Biophys. , vol.545 , pp. 141-147
    • Ledetzky, N.1    Osawa, A.2    Iki, K.3    Pollmann, H.4    Gassel, S.5    Breitenbach, J.6    Shindo, K.7    Sandmann, G.8


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