Novel high-sensitivity cardiac troponin i assay in patients with suspected acute coronary syndrome

Heart

Volumn 105, Issue 8, 2019, Pages 616-622

  Chapman, Andrew R ^a   Fujisawa, Takeshi ^a   Lee, Kuan Ken ^a   Andrews, Jack Patrick ^a   Anand, Atul ^a   Sandeman, Dennis ^a   Ferry, Amy V ^a   Stewart, Stacey ^a   Marshall, Lucy ^a   Strachan, Fiona E ^a   Gray, Alasdair ^b   Newby, David E ^a   Shah, Anoop S V ^a   Mills, Nicholas L ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

acute coronary syndromes

Indexed keywords

TROPONIN I; BIOLOGICAL MARKER;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; CLINICAL PRACTICE; FEMALE; HEART DEATH; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; MIDDLE AGED; PREDICTIVE VALUE; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; BLOOD; CLINICAL PATHWAY; CLINICAL TRIAL; DEATH; EARLY DIAGNOSIS; EPIDEMIOLOGY; MORTALITY; OUTCOME ASSESSMENT; PROCEDURES; RISK ASSESSMENT; SCOTLAND;

ACUTE CORONARY SYNDROME; AGED; BIOMARKERS; CRITICAL PATHWAYS; DEATH; EARLY DIAGNOSIS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OUTCOME ASSESSMENT (HEALTH CARE); RISK ASSESSMENT; SCOTLAND; TROPONIN I;

EID: 85056701131     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/heartjnl-2018-314093     Document Type: Article

References (26)

1. T hygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Eur Heart J 2012;33:2551-67.
2. C hapman AR, Lee KK, McAllister DA, et al. Association of high-sensitivity cardiac troponin i concentration with cardiac outcomes in patients with suspected acute coronary syndrome. JAMA 2017;318:1913-24.
3. C hapman AR, Anand A, Boeddinghaus J, et al. Comparison of the efficacy and safety of early rule-out pathways for acute myocardial infarction. Circulation 2017;135:1586-96.
4. Boeddinghaus J, Twerenbold R, Nestelberger T, et al. Clinical validation of a novel high-sensitivity cardiac troponin i assay for early diagnosis of acute myocardial infarction. Clin Chem 2018;64:1347-60.
5. R offi M, Patrono C, Collet JP, et al. 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: task force for the management of acute coronary syndromes in patients presenting without persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 2016;37:267-315.
6. Mueller C, Giannitsis E, Christ M, et al. Multicenter evaluation of a 0-hour/1-hour algorithm in the diagnosis of myocardial infarction with high-sensitivity cardiac troponin T. Ann Emerg Med 2016;68:76-87.
7. Pickering JW, Greenslade JH, Cullen L, et al. Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction. Heart 2016;102:1270-8.
8. S hah AS, Anand A, Sandoval Y, et al. High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study. Lancet 2015;386:2481-8.
9. T hygesen K, Mair J, Giannitsis E, et al. How to use high-sensitivity cardiac troponins in acute cardiac care. Eur Heart J 2012;33:2252-7.
10. A nderson F, FitzGerald G. Methods and formulas used to calculate the GRACE Risk Scores for patients presenting to hospital with an acute coronary syndrome. www. outcomes-umassmed. org/ GRACE / publicfiles/ GRACE RiskModel Coefficients. pdf2010.
11. Brown L, Cai T, DasGupta A. Interval estimation for a binomial proportion. Stat Sci 2001;16:101-33.
12. Bossuyt PM, Reitsma JB, Bruns DE, et al. STAR D 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ 2015;351:h5527.
13. A pple FS, Sandoval Y, Jaffe AS, et al. Cardiac troponin assays: guide to understanding analytical characteristics and their impact on clinical care. Clin Chem 2017;63:73-81.
14. A pple FS, Jaffe AS, Collinson P, et al. IFCC educational materials on selected analytical and clinical applications of high sensitivity cardiac troponin assays. Clin Biochem 2015;48(4-5):201-3.
15. T han M, Herbert M, Flaws D, et al. What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the Emergency Department?: a clinical survey. Int J Cardiol 2013;166:752-4.
16. Pickering JW, Than MP, Cullen L, et al. Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin t measurement below the limit of detection: a collaborative Meta-analysis. Ann Intern Med 2017;166:715-24.
17. Kavsak PA, Don-Wauchope AC , Hill SA, et al. Acceptable analytical variation may exceed high-sensitivity cardiac troponin i cutoffs in early rule-out and rule-in acute myocardial infarction algorithms. Clin Chem 2016;62:887-9.
18. T hygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction. Eur Heart J 2018;2018.
19. S hah ASV, Anand A, Strachan FE, et al. High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, clusterrandomised controlled trial. Lancet 2018;392:919-28.
20. Boeddinghaus J, Nestelberger T, Twerenbold R, et al. Direct comparison of 4 very early rule-out strategies for acute myocardial infarction using high-sensitivity cardiac troponin I. Circulation 2017;135:1597-611.
21. Van Den Berg P, Body R. The HEART score for early rule out of acute coronary syndromes in the emergency department: a systematic review and meta-analysis. Eur Heart J Acute Cardiovasc Care 2018;7:2048872617710788.
22. Backus BE, Six AJ, Kelder JC, et al. A prospective validation of the HEART score for chest pain patients at the emergency department. Int J Cardiol 2013;168:2153-8.
23. A ntman EM, Cohen M, Bernink PJ, et al. The TIMI risk score for unstable angina/ non-ST elevation MI: A method for prognostication and therapeutic decision making. JAMA 2000;284:835-42.
24. T han M, Flaws D, Sanders S, et al. Development and validation of the emergency department assessment of chest pain score and 2 h accelerated diagnostic protocol. Emerg Med Australas 2014;26:34-44.
25. C hapman AR, Hesse K, Andrews J, et al. High-sensitivity cardiac troponin i and clinical risk scores in patients with suspected acute coronary syndrome. Circulation 2018;138:1654-65.
26. C hapman AR, Mills NL. A single blood test to rule out acute coronary syndrome. Heart 2018;104:632-3.