Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures

The Lancet Respiratory Medicine

Volumn 6, Issue 11, 2018, Pages 846-854

  Hui, Kenrie P Y ^a   Ching, Rachel H H ^a   Chan, Stan K H ^a   Nicholls, John M ^a   Sachs, Norman ^b,c   Clevers, Hans ^b   Peiris, J S Malik ^a   Chan, Michael C W ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HUBRECHT INSTITUTE   (Netherlands)

^c VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CHEMOKINE; CYTOKINE; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1;

AIRWAY; ARTICLE; AVIAN INFLUENZA VIRUS; BRONCHUS TISSUE; CILIATED EPITHELIUM CELL; CONTROLLED STUDY; CYTOKINE RELEASE; EX VIVO STUDY; EXPLANT; GOBLET CELL; HONG KONG; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLUENZA A (H1N1); INFLUENZA A (H5N1); INFLUENZA A (H7N9); INFLUENZA A VIRUS; INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H5N1); INFLUENZA A VIRUS (H5N6); INFLUENZA A VIRUS (H7N9); INFLUENZA VIRUS; INNATE IMMUNITY; KINETICS; LUNG ALVEOLUS CELL; LUNG PARENCHYMA; LUNG RESECTION; NONHUMAN; ORGANOID; PATIENT CARE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; T LYMPHOCYTE; TISSUE CULTURE; UNIVERSITY HOSPITAL; VIRAL TROPISM; VIRUS CELL INTERACTION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BRONCHUS; COMPARATIVE STUDY; IMMUNOLOGY; INFLUENZA; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; VIROLOGY;

ANIMALS; BRONCHI; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; ORGANOIDS; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; VIRAL TROPISM; VIRUS REPLICATION;

EID: 85056379601     PISSN: 22132600     EISSN: 22132619     Source Type: Journal    
DOI: 10.1016/S2213-2600(18)30236-4     Document Type: Article

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