-
1
-
-
0032874879
-
De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs
-
PMID: 104 90662
-
Adachi-Yamada T, Gotoh T, Sugimura I, Tateno M, Nishida Y, Onuki T, Date H. 1999. De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs. Molecular and Cellular Biology 19:7276–7286. DOI: https://doi.org/10.1128/MCB.19.10.7276, PMID: 104 90662
-
(1999)
Molecular and Cellular Biology
, vol.19
, pp. 7276-7286
-
-
Adachi-Yamada, T.1
Gotoh, T.2
Sugimura, I.3
Tateno, M.4
Nishida, Y.5
Onuki, T.6
Date, H.7
-
2
-
-
33646740793
-
Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP
-
16682643
-
Ataman B, Ashley J, Gorczyca D, Gorczyca M, Mathew D, Wichmann C, Sigrist SJ, Budnik V. 2006. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. PNAS 103: 7841–7846. DOI: https://doi.org/10.1073/pnas.0600387103, PMID: 16682643
-
(2006)
PNAS
, vol.103
, pp. 7841-7846
-
-
Ataman, B.1
Ashley, J.2
Gorczyca, D.3
Gorczyca, M.4
Mathew, D.5
Wichmann, C.6
Sigrist, S.J.7
Budnik, V.8
-
3
-
-
84930044947
-
Lipid membrane domains in the brain
-
25677824
-
Aureli M, Grassi S, Prioni S, Sonnino S, Prinetti A. 2015. Lipid membrane domains in the brain. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1851:1006–1016. DOI: https://doi.org/10.1016/j. bbalip.2015.02.001, PMID: 25677824
-
(2015)
Biochimica Et Biophysica Acta (Bba)-Molecular and Cell Biology of Lipids
, vol.1851
, pp. 1006-1016
-
-
Aureli, M.1
Grassi, S.2
Prioni, S.3
Sonnino, S.4
Prinetti, A.5
-
4
-
-
36749073357
-
Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts
-
18026091
-
Balasubramanian N, Scott DW, Castle JD, Casanova JE, Schwartz MA. 2007. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nature Cell Biology 9:1381–1391. DOI: https://doi.org/10.1038/ncb1657, PMID: 18026091
-
(2007)
Nature Cell Biology
, vol.9
, pp. 1381-1391
-
-
Balasubramanian, N.1
Scott, D.W.2
Castle, J.D.3
Casanova, J.E.4
Schwartz, M.A.5
-
5
-
-
71249164368
-
Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila
-
19834458
-
Bauer R, Voelzmann A, Breiden B, Schepers U, Farwanah H, Hahn I, Eckardt F, Sandhoff K, Hoch M. 2009. Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila. The EMBO Journal 28:3706–3716. DOI: https://doi.org/10.1038/emboj.2009.305, PMID: 19834458
-
(2009)
The EMBO Journal
, vol.28
, pp. 3706-3716
-
-
Bauer, R.1
Voelzmann, A.2
Breiden, B.3
Schepers, U.4
Farwanah, H.5
Hahn, I.6
Eckardt, F.7
Sandhoff, K.8
Hoch, M.9
-
6
-
-
79952068294
-
The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases
-
20832291
-
Bayat V, Jaiswal M, Bellen HJ. 2011. The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases. Current Opinion in Neurobiology 21:182–188. DOI: https://doi.org/10. 1016/j.conb.2010.08.014, PMID: 20832291
-
(2011)
Current Opinion in Neurobiology
, vol.21
, pp. 182-188
-
-
Bayat, V.1
Jaiswal, M.2
Bellen, H.J.3
-
7
-
-
84948451733
-
Morgan’s legacy: Fruit flies and the functional annotation of conserved genes
-
26406362
-
Bellen HJ, Yamamoto S. 2015. Morgan’s legacy: fruit flies and the functional annotation of conserved genes. Cell 163:12–14. DOI: https://doi.org/10.1016/j.cell.2015.09.009, PMID: 26406362
-
(2015)
Cell
, vol.163
, pp. 12-14
-
-
Bellen, H.J.1
Yamamoto, S.2
-
8
-
-
78049336214
-
Survival strategies of a sterol auxotroph
-
20940226
-
Carvalho M, Schwudke D, Sampaio JL, Palm W, Riezman I, Dey G, Gupta GD, Mayor S, Riezman H, Shevchenko A, Kurzchalia TV, Eaton S. 2010. Survival strategies of a sterol auxotroph. Development 137:3675–3685. DOI: https://doi.org/10.1242/dev.044560, PMID: 20940226
-
(2010)
Development
, vol.137
, pp. 3675-3685
-
-
Carvalho, M.1
Schwudke, D.2
Sampaio, J.L.3
Palm, W.4
Riezman, I.5
Dey, G.6
Gupta, G.D.7
Mayor, S.8
Riezman, H.9
Shevchenko, A.10
Kurzchalia, T.V.11
Eaton, S.12
-
9
-
-
0035826727
-
SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis
-
11331757
-
Chamberlain LH, Burgoyne RD, Gould GW. 2001. SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis. PNAS 98:5619–5624. DOI: https://doi.org/10.1073/pnas. 091502398, PMID: 11331757
-
(2001)
PNAS
, vol.98
, pp. 5619-5624
-
-
Chamberlain, L.H.1
Burgoyne, R.D.2
Gould, G.W.3
-
10
-
-
34249903105
-
Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila
-
17498683
-
Chen YW, Pedersen JW, Wandall HH, Levery SB, Pizette S, Clausen H, Cohen SM. 2007. Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila. Developmental Biology 306:736–749. DOI: https://doi.org/10.1016/j.ydbio.2007.04.013, PMID: 17498683
-
(2007)
Developmental Biology
, vol.306
, pp. 736-749
-
-
Chen, Y.W.1
Pedersen, J.W.2
Wandall, H.H.3
Levery, S.B.4
Pizette, S.5
Clausen, H.6
Cohen, S.M.7
-
11
-
-
79959336760
-
Regulation of human EGF receptor by lipids
-
21571640
-
Coskun Ü, Grzybek M, Drechsel D, Simons K. 2011. Regulation of human EGF receptor by lipids. PNAS 108: 9044–9048. DOI: https://doi.org/10.1073/pnas.1105666108, PMID: 21571640
-
(2011)
PNAS
, vol.108
, pp. 9044-9048
-
-
Coskun, Ü.1
Grzybek, M.2
Drechsel, D.3
Simons, K.4
-
12
-
-
84860794041
-
Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension
-
22493273
-
Dahlgaard K, Jung A, Qvortrup K, Clausen H, Kjaerulff O, Wandall HH. 2012. Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension. PNAS 109:6987–6992. DOI: https://doi.org/10. 1073/pnas.1115453109, PMID: 22493273
-
(2012)
PNAS
, vol.109
, pp. 6987-6992
-
-
Dahlgaard, K.1
Jung, A.2
Qvortrup, K.3
Clausen, H.4
Kjaerulff, O.5
Wandall, H.H.6
-
13
-
-
33845346791
-
Inhibitors of sphingolipid metabolism enzymes
-
17049336
-
Delgado A, Casas J, Llebaria A, Abad JL, Fabrias G. 2006. Inhibitors of sphingolipid metabolism enzymes. Biochimica et Biophysica Acta (BBA)-Biomembranes 1758:1957–1977. DOI: https://doi.org/10.1016/j. bbamem.2006.08.017, PMID: 17049336
-
(2006)
Biochimica Et Biophysica Acta (Bba)-Biomembranes
, vol.1758
, pp. 1957-1977
-
-
Delgado, A.1
Casas, J.2
Llebaria, A.3
Abad, J.L.4
Fabrias, G.5
-
14
-
-
84904700172
-
Interaction of Alzheimer’s b-amyloid peptides with cholesterol: Mechanistic insights into amyloid pore formation
-
Di Scala C, Chahinian H, Yahi N, Garmy N, Fantini J. 2014. Interaction of Alzheimer’s b-amyloid peptides with cholesterol: mechanistic insights into amyloid pore formation. Biochemistry 53:4489–4502. DOI: https://doi. org/10.1021/bi500373k, PMID: 25000142
-
(2014)
Biochemistry
, vol.53
, pp. 4489-4502
-
-
Di Scala, C.1
Chahinian, H.2
Yahi, N.3
Garmy, N.4
Fantini, J.5
-
15
-
-
79954534373
-
Molecular basis for the glycosphingolipid-binding specificity of a-synuclein: Key role of tyrosine 39 in membrane insertion
-
21396938
-
Fantini J, Yahi N. 2011. Molecular basis for the glycosphingolipid-binding specificity of a-synuclein: key role of tyrosine 39 in membrane insertion. Journal of Molecular Biology 408:654–669. DOI: https://doi.org/10.1016/j. jmb.2011.03.009, PMID: 21396938
-
(2011)
Journal of Molecular Biology
, vol.408
, pp. 654-669
-
-
Fantini, J.1
Yahi, N.2
-
17
-
-
0842304658
-
Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster
-
13130120
-
Fyrst H, Herr DR, Harris GL, Saba JD. 2004. Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster. Journal of Lipid Research 45:54–62. DOI: https://doi.org/10.1194/jlr.M300005-JLR200, PMID: 13130120
-
(2004)
Journal of Lipid Research
, vol.45
, pp. 54-62
-
-
Fyrst, H.1
Herr, D.R.2
Harris, G.L.3
Saba, J.D.4
-
18
-
-
0033836520
-
The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components
-
10930469
-
Gagescu R, Demaurex N, Parton RG, Hunziker W, Huber LA, Gruenberg J. 2000. The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components. Molecular Biology of the Cell 11:2775–2791. DOI: https://doi.org/10.1091/mbc.11.8.2775, PMID: 10930469
-
(2000)
Molecular Biology of the Cell
, vol.11
, pp. 2775-2791
-
-
Gagescu, R.1
Demaurex, N.2
Parton, R.G.3
Hunziker, W.4
Huber, L.A.5
Gruenberg, J.6
-
19
-
-
35548942304
-
Porcupine-mediated lipid-modification regulates the activity and distribution of Wnt proteins in the chick neural tube
-
17720697
-
Galli LM, Barnes TL, Secrest SS, Kadowaki T, Burrus LW. 2007. Porcupine-mediated lipid-modification regulates the activity and distribution of Wnt proteins in the chick neural tube. Development 134:3339–3348. DOI: https://doi.org/10.1242/dev.02881, PMID: 17720697
-
(2007)
Development
, vol.134
, pp. 3339-3348
-
-
Galli, L.M.1
Barnes, T.L.2
Secrest, S.S.3
Kadowaki, T.4
Burrus, L.W.5
-
20
-
-
0030477867
-
The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis
-
9012507
-
Goode S, Melnick M, Chou TB, Perrimon N. 1996. The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis. Development 122: 3863–3879. PMID: 9012507
-
(1996)
Development
, vol.122
, pp. 3863-3879
-
-
Goode, S.1
Melnick, M.2
Chou, T.B.3
Perrimon, N.4
-
21
-
-
84900458436
-
Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila
-
24478335
-
Gratz SJ, Ukken FP, Rubinstein CD, Thiede G, Donohue LK, Cummings AM, O’Connor-Giles KM. 2014. Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila. Genetics 196:961–971. DOI: https://doi.org/10.1534/genetics.113.160713, PMID: 24478335
-
(2014)
Genetics
, vol.196
, pp. 961-971
-
-
Gratz, S.J.1
Ukken, F.P.2
Rubinstein, C.D.3
Thiede, G.4
Donohue, L.K.5
Cummings, A.M.6
O’connor-Giles, K.M.7
-
22
-
-
77149159510
-
Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster
-
20176925
-
Hamel S, Fantini J, Schweisguth F. 2010. Notch ligand activity is modulated by glycosphingolipid membrane composition in Drosophila melanogaster. The Journal of Cell Biology 188:581–594. DOI: https://doi.org/10. 1083/jcb.200907116, PMID: 20176925
-
(2010)
The Journal of Cell Biology
, vol.188
, pp. 581-594
-
-
Hamel, S.1
Fantini, J.2
Schweisguth, F.3
-
23
-
-
84943592745
-
Transmission, development, and plasticity of synapses
-
26447126
-
Harris KP, Littleton JT. 2015. Transmission, development, and plasticity of synapses. Genetics 201:345–375. DOI: https://doi.org/10.1534/genetics.115.176529, PMID: 26447126
-
(2015)
Genetics
, vol.201
, pp. 345-375
-
-
Harris, K.P.1
Littleton, J.T.2
-
24
-
-
0037996880
-
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability
-
12716933
-
Hering H, Lin CC, Sheng M. 2003. Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. The Journal of Neuroscience 23:3262–3271. DOI: https://doi.org/10.1523/JNEUROSCI.23-08-03262.2003, PMID: 12716933
-
(2003)
The Journal of Neuroscience
, vol.23
, pp. 3262-3271
-
-
Hering, H.1
Lin, C.C.2
Sheng, M.3
-
25
-
-
84355162717
-
Porcupine-mediated lipidation is required for Wnt recognition by Wls
-
22108505
-
Herr P, Basler K. 2012. Porcupine-mediated lipidation is required for Wnt recognition by Wls. Developmental Biology 361:392–402. DOI: https://doi.org/10.1016/j.ydbio.2011.11.003, PMID: 22108505
-
(2012)
Developmental Biology
, vol.361
, pp. 392-402
-
-
Herr, P.1
Basler, K.2
-
26
-
-
84864395840
-
WNT secretion and signalling in human disease
-
22796206
-
Herr P, Hausmann G, Basler K. 2012. WNT secretion and signalling in human disease. Trends in Molecular Medicine 18:483–493. DOI: https://doi.org/10.1016/j.molmed.2012.06.008, PMID: 22796206
-
(2012)
Trends in Molecular Medicine
, vol.18
, pp. 483-493
-
-
Herr, P.1
Hausmann, G.2
Basler, K.3
-
27
-
-
77649114923
-
Glycolipid trafficking in Drosophila undergoes pathway switching in response to aberrant cholesterol levels
-
20053687
-
Hortsch R, Lee E, Erathodiyil N, Hebbar S, Steinert S, Lee JY, Chua DS, Kraut R. 2010. Glycolipid trafficking in Drosophila undergoes pathway switching in response to aberrant cholesterol levels. Molecular Biology of the Cell 21:778–790. DOI: https://doi.org/10.1091/mbc.e09-01-0005, PMID: 20053687
-
(2010)
Molecular Biology of the Cell
, vol.21
, pp. 778-790
-
-
Hortsch, R.1
Lee, E.2
Erathodiyil, N.3
Hebbar, S.4
Steinert, S.5
Lee, J.Y.6
Chua, D.S.7
Kraut, R.8
-
28
-
-
84995407015
-
Acsl, the Drosophila ortholog of intellectualdisability-related ACSL4, inhibits synaptic growth by altered lipids
-
27656110
-
Huang Y, Huang S, Lam SM, Liu Z, Shui G, Zhang YQ. 2016. Acsl, the Drosophila ortholog of intellectualdisability-related ACSL4, inhibits synaptic growth by altered lipids. Journal of cell science 129:4034–4045. DOI: https://doi.org/10.1242/jcs.195032, PMID: 27656110
-
(2016)
Journal of Cell Science
, vol.129
, pp. 4034-4045
-
-
Huang, Y.1
Huang, S.2
Lam, S.M.3
Liu, Z.4
Shui, G.5
Zhang, Y.Q.6
-
29
-
-
84863543371
-
Structural basis of Wnt recognition by Frizzled
-
22653731
-
Janda CY, Waghray D, Levin AM, Thomas C, Garcia KC. 2012. Structural basis of Wnt recognition by Frizzled. Science 337:59–64. DOI: https://doi.org/10.1126/science.1222879, PMID: 22653731
-
(2012)
Science
, vol.337
, pp. 59-64
-
-
Janda, C.Y.1
Waghray, D.2
Levin, A.M.3
Thomas, C.4
Garcia, K.C.5
-
30
-
-
24644513422
-
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth
-
16109770
-
Jennemann R, Sandhoff R, Wang S, Kiss E, Gretz N, Zuliani C, Martin-Villalba A, Jäger R, Schorle H, Kenzelmann M, Bonrouhi M, Wiegandt H, Gröne HJ. 2005. Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. PNAS 102:12459–12464. DOI: https://doi.org/10.1073/pnas.0500893102, PMID: 16109770
-
(2005)
PNAS
, vol.102
, pp. 12459-12464
-
-
Jennemann, R.1
Sandhoff, R.2
Wang, S.3
Kiss, E.4
Gretz, N.5
Zuliani, C.6
Martin-Villalba, A.7
Jäger, R.8
Schorle, H.9
Kenzelmann, M.10
Bonrouhi, M.11
Wiegandt, H.12
Gröne, H.J.13
-
31
-
-
84924651313
-
Notum deacylates Wnt proteins to suppress signalling activity
-
25731175
-
Kakugawa S, Langton PF, Zebisch M, Howell S, Chang TH, Liu Y, Feizi T, Bineva G, O’Reilly N, Snijders AP, Jones EY, Vincent JP. 2015. Notum deacylates Wnt proteins to suppress signalling activity. Nature 519:187–192. DOI: https://doi.org/10.1038/nature14259, PMID: 25731175
-
(2015)
Nature
, vol.519
, pp. 187-192
-
-
Kakugawa, S.1
Langton, P.F.2
Zebisch, M.3
Howell, S.4
Chang, T.H.5
Liu, Y.6
Feizi, T.7
Bineva, G.8
O’Reilly, N.9
Snijders, A.P.10
Jones, E.Y.11
Vincent, J.P.12
-
32
-
-
84894104048
-
Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction
-
24553932
-
Kerr KS, Fuentes-Medel Y, Brewer C, Barria R, Ashley J, Abruzzi KC, Sheehan A, Tasdemir-Yilmaz OE, Freeman MR, Budnik V. 2014. Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. Journal of Neuroscience 34:2910–2920. DOI: https://doi.org/10.1523/JNEUROSCI.3714-13.2014, PMID: 24553932
-
(2014)
Journal of Neuroscience
, vol.34
, pp. 2910-2920
-
-
Kerr, K.S.1
Fuentes-Medel, Y.2
Brewer, C.3
Barria, R.4
Ashley, J.5
Abruzzi, K.C.6
Sheehan, A.7
Tasdemir-Yilmaz, O.E.8
Freeman, M.R.9
Budnik, V.10
-
33
-
-
33846079552
-
Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events
-
17079274
-
Khodosh R, Augsburger A, Schwarz TL, Garrity PA. 2006. Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events. Development 133:4655–4665. DOI: https://doi.org/10.1242/dev.02650, PMID: 17079274
-
(2006)
Development
, vol.133
, pp. 4655-4665
-
-
Khodosh, R.1
Augsburger, A.2
Schwarz, T.L.3
Garrity, P.A.4
-
34
-
-
78049241963
-
WASP is activated by phosphatidylinositol-4,5bisphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling
-
Khuong TM, Habets RLP, Slabbaert JR, Verstreken P. 2010. WASP is activated by phosphatidylinositol-4,5bisphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling. PANS 107:17379–17384. DOI: https://doi.org/10.1073/pnas.1001794107
-
(2010)
PANS
, vol.107
, pp. 17379-17384
-
-
Khuong, T.M.1
Habets, R.L.P.2
Slabbaert, J.R.3
Verstreken, P.4
-
35
-
-
84875523175
-
Synaptic PI(3,4,5)P3 is required for Syntaxin1A clustering and neurotransmitter release
-
23522045
-
Khuong TM, Habets RL, Kuenen S, Witkowska A, Kasprowicz J, Swerts J, Jahn R, van den Bogaart G, Verstreken P. 2013. Synaptic PI(3,4,5)P3 is required for Syntaxin1A clustering and neurotransmitter release. Neuron 77: 1097–1108. DOI: https://doi.org/10.1016/j.neuron.2013.01.025, PMID: 23522045
-
(2013)
Neuron
, vol.77
, pp. 1097-1108
-
-
Khuong, T.M.1
Habets, R.L.2
Kuenen, S.3
Witkowska, A.4
Kasprowicz, J.5
Swerts, J.6
Jahn, R.7
van den Bogaart, G.8
Verstreken, P.9
-
36
-
-
84928828516
-
A Lipid-TORC1 pathway promotes neuronal development and foraging behavior under both fed and fasted conditions in C. Elegans
-
25892013
-
Kniazeva M, Zhu H, Sewell AK, Han M. 2015. A Lipid-TORC1 pathway promotes neuronal development and foraging behavior under both fed and fasted conditions in C. elegans. Developmental Cell 33:260–271. DOI: https://doi.org/10.1016/j.devcel.2015.02.015, PMID: 25892013
-
(2015)
Developmental Cell
, vol.33
, pp. 260-271
-
-
Kniazeva, M.1
Zhu, H.2
Sewell, A.K.3
Han, M.4
-
37
-
-
70349648496
-
A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila
-
19587536
-
Köhler K, Brunner E, Guan XL, Boucke K, Greber UF, Mohanty S, Barth JM, Wenk MR, Hafen E. 2009. A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy 5:980–990. DOI: https://doi.org/10.4161/auto.5.7.9325, PMID: 19587536
-
(2009)
Autophagy
, vol.5
, pp. 980-990
-
-
Köhler, K.1
Brunner, E.2
Guan, X.L.3
Boucke, K.4
Greber, U.F.5
Mohanty, S.6
Barth, J.M.7
Wenk, M.R.8
Hafen, E.9
-
38
-
-
84860852182
-
Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons
-
22437826
-
Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. 2012. Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Journal of Biological Chemistry 287:16820– 16834. DOI: https://doi.org/10.1074/jbc.M112.342667, PMID: 22437826
-
(2012)
Journal of Biological Chemistry
, vol.287
, pp. 16820-16834
-
-
Koles, K.1
Nunnari, J.2
Korkut, C.3
Barria, R.4
Brewer, C.5
Li, Y.6
Leszyk, J.7
Zhang, B.8
Budnik, V.9
-
39
-
-
70349829157
-
Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless
-
19837038
-
Korkut C, Ataman B, Ramachandran P, Ashley J, Barria R, Gherbesi N, Budnik V. 2009. Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell 139:393–404. DOI: https://doi.org/10.1016/j. cell.2009.07.051, PMID: 19837038
-
(2009)
Cell
, vol.139
, pp. 393-404
-
-
Korkut, C.1
Ataman, B.2
Ramachandran, P.3
Ashley, J.4
Barria, R.5
Gherbesi, N.6
Budnik, V.7
-
40
-
-
69249097386
-
WNTs tune up the neuromuscular junction
-
19693027
-
Korkut C, Budnik V. 2009. WNTs tune up the neuromuscular junction. Nature Reviews Neuroscience 10:627–634. DOI: https://doi.org/10.1038/nrn2681, PMID: 19693027
-
(2009)
Nature Reviews Neuroscience
, vol.10
, pp. 627-634
-
-
Korkut, C.1
Budnik, V.2
-
41
-
-
33748457564
-
DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis
-
16943182
-
Kunisaki Y, Nishikimi A, Tanaka Y, Takii R, Noda M, Inayoshi A, Watanabe K, Sanematsu F, Sasazuki T, Sasaki T, Fukui Y. 2006. DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. The Journal of Cell Biology 174:647–652. DOI: https://doi.org/10.1083/jcb.200602142, PMID: 16943182
-
(2006)
The Journal of Cell Biology
, vol.174
, pp. 647-652
-
-
Kunisaki, Y.1
Nishikimi, A.2
Tanaka, Y.3
Takii, R.4
Noda, M.5
Inayoshi, A.6
Watanabe, K.7
Sanematsu, F.8
Sasazuki, T.9
Sasaki, T.10
Fukui, Y.11
-
42
-
-
74849118341
-
Lipid rafts as a membrane-organizing principle
-
20044567
-
Lingwood D, Simons K. 2010. Lipid rafts as a membrane-organizing principle. Science 327:46–50. DOI: https://doi.org/10.1126/science.1174621, PMID: 20044567
-
(2010)
Science
, vol.327
, pp. 46-50
-
-
Lingwood, D.1
Simons, K.2
-
43
-
-
84894060302
-
DAcsl, the Drosophila ortholog of acyl-CoA synthetase long-chain family member 3 and 4, inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling
-
24553921
-
Liu Z, Huang Y, Hu W, Huang S, Wang Q, Han J, Zhang YQ. 2014. dAcsl, the Drosophila ortholog of acyl-CoA synthetase long-chain family member 3 and 4, inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling. Journal of Neuroscience 34:2785–2796. DOI: https://doi.org/10.1523/JNEUROSCI.3547-13.2014, PMID: 24553921
-
(2014)
Journal of Neuroscience
, vol.34
, pp. 2785-2796
-
-
Liu, Z.1
Huang, Y.2
Hu, W.3
Huang, S.4
Wang, Q.5
Han, J.6
Zhang, Y.Q.7
-
44
-
-
28144441697
-
Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2
-
Mathew D, Ataman B, Chen J, Zhang Y, Cumberledge S, Budnik V. 2005. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science 310:1344–1347. DOI: https://doi.org/10. 1126/science.1117051, PMID: 16311339
-
(2005)
Science
, vol.310
, pp. 1344-1347
-
-
Mathew, D.1
Ataman, B.2
Chen, J.3
Zhang, Y.4
Cumberledge, S.5
Budnik, V.6
-
45
-
-
58149334854
-
Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction
-
18945895
-
Miech C, Pauer HU, He X, Schwarz TL. 2008. Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction. Journal of Neuroscience 28:10875–10884. DOI: https://doi.org/10.1523/JNEUROSCI.0164-08.2008, PMID: 18945895
-
(2008)
Journal of Neuroscience
, vol.28
, pp. 10875-10884
-
-
Miech, C.1
Pauer, H.U.2
He, X.3
Schwarz, T.L.4
-
46
-
-
77955058547
-
The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development
-
20601947
-
Mosca TJ, Schwarz TL. 2010. The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nature Neuroscience 13:935–943. DOI: https://doi.org/10.1038/nn.2593, PMID: 20601947
-
(2010)
Nature Neuroscience
, vol.13
, pp. 935-943
-
-
Mosca, T.J.1
Schwarz, T.L.2
-
47
-
-
0036848075
-
The Drosophila Wnt, wingless, provides an essential signal for pre-and postsynaptic differentiation
-
12419243
-
Packard M, Koo ES, Gorczyca M, Sharpe J, Cumberledge S, Budnik V. 2002. The Drosophila Wnt, wingless, provides an essential signal for pre-and postsynaptic differentiation. Cell 111:319–330. DOI: https://doi.org/10.1016/S0092-8674(02)01047-4, PMID: 12419243
-
(2002)
Cell
, vol.111
, pp. 319-330
-
-
Packard, M.1
Koo, E.S.2
Gorczyca, M.3
Sharpe, J.4
Cumberledge, S.5
Budnik, V.6
-
48
-
-
64549109758
-
Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken
-
19144719
-
Pizette S, Rabouille C, Cohen SM, Thérond P. 2009. Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken. Development 136:551–561. DOI: https://doi.org/10.1242/dev.031104, PMID: 19144719
-
(2009)
Development
, vol.136
, pp. 551-561
-
-
Pizette, S.1
Rabouille, C.2
Cohen, S.M.3
Thérond, P.4
-
49
-
-
84904654756
-
Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila
-
25002478
-
Port F, Chen HM, Lee T, Bullock SL. 2014. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. PNAS 111:E2967–E2976. DOI: https://doi.org/10.1073/pnas.1405500111, PMID: 25002478
-
(2014)
PNAS
, vol.111
, pp. E2967-E2976
-
-
Port, F.1
Chen, H.M.2
Lee, T.3
Bullock, S.L.4
-
50
-
-
84888108873
-
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9
-
Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, Perrimon N, Ni JQ, Jy J, Jq N. 2013. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. PNAS 110:19012–19017. DOI: https://doi.org/10.1073/pnas.1318481110, PMID: 241 91015
-
(2013)
PNAS
, vol.110
, pp. 19012-19017
-
-
Ren, X.1
Sun, J.2
Housden, B.E.3
Hu, Y.4
Roesel, C.5
Lin, S.6
Liu, L.P.7
Yang, Z.8
Mao, D.9
Sun, L.10
Wu, Q.11
Ji, J.Y.12
Xi, J.13
Mohr, S.E.14
Xu, J.15
Perrimon, N.16
Ni, J.Q.17
Jy, J.18
Jq, N.19
-
51
-
-
7444255626
-
Membrane targeting of lipid modified signal transduction proteins
-
15376622
-
Resh MD. 2004. Membrane targeting of lipid modified signal transduction proteins. Sub-Cellular Biochemistry 37:217–232. DOI: https://doi.org/10.1007/978-1-4757-5806-1_6, PMID: 15376622
-
(2004)
Sub-Cellular Biochemistry
, vol.37
, pp. 217-232
-
-
Resh, M.D.1
-
52
-
-
0033597141
-
Association of sterol-and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains
-
10207028
-
Rietveld A, Neutz S, Simons K, Eaton S. 1999. Association of sterol-and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. Journal of Biological Chemistry 274:12049–12054. DOI: https://doi.org/10.1074/jbc.274.17.12049, PMID: 10207028
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 12049-12054
-
-
Rietveld, A.1
Neutz, S.2
Simons, K.3
Eaton, S.4
-
53
-
-
0033710887
-
Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth
-
Roos J, Hummel T, Ng N, Klämbt C, Davis GW. 2000. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron 26:371–382. DOI: https://doi.org/10.1016/S0896-6273(00)81170-8
-
(2000)
Neuron
, vol.26
, pp. 371-382
-
-
Roos, J.1
Hummel, T.2
Ng, N.3
Klämbt, C.4
Davis, G.W.5
-
54
-
-
84863913174
-
Wnt signaling in the vertebrate central nervous system: From axon guidance to synaptic function
-
22300976
-
Salinas PC. 2012. Wnt signaling in the vertebrate central nervous system: from axon guidance to synaptic function. Cold Spring Harbor Perspectives in Biology 4:a008003. DOI: https://doi.org/10.1101/cshperspect. a008003, PMID: 22300976
-
(2012)
Cold Spring Harbor Perspectives in Biology
, vol.4
-
-
Salinas, P.C.1
-
55
-
-
0028817584
-
Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission
-
7834751
-
Schulze KL, Broadie K, Perin MS, Bellen HJ. 1995. Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell 80:311–320. DOI: https://doi.org/10.1016/0092-8674(95)90414-X, PMID: 7834751
-
(1995)
Cell
, vol.80
, pp. 311-320
-
-
Schulze, K.L.1
Broadie, K.2
Perin, M.S.3
Bellen, H.J.4
-
56
-
-
0030273379
-
Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth
-
8893022
-
Schuster CM, Davis GW, Fetter RD, Goodman CS. 1996. Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth. Neuron 17:641–654. DOI: https://doi.org/10.1016/S0896-6273(00)80197-X, PMID: 8893022
-
(1996)
Neuron
, vol.17
, pp. 641-654
-
-
Schuster, C.M.1
Davis, G.W.2
Fetter, R.D.3
Goodman, C.S.4
-
57
-
-
0037031941
-
The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis
-
Schwientek T, Keck B, Levery SB, Jensen MA, Pedersen JW, Wandall HH, Stroud M, Cohen SM, Amado M, Clausen H. 2002. The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis. Journal of Biological Chemistry 277:32421–32429. DOI: https://doi.org/10.1074/jbc.M206213200, PMID: 12130651
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 32421-32429
-
-
Schwientek, T.1
Keck, B.2
Levery, S.B.3
Jensen, M.A.4
Pedersen, J.W.5
Wandall, H.H.6
Stroud, M.7
Cohen, S.M.8
Amado, M.9
Clausen, H.10
-
58
-
-
1342306818
-
Nanoscale organization of multiple GPI-Anchored proteins in living cell membranes
-
Sharma P, Varma R, Sarasij RC, Ira, Gousset K, Krishnamoorthy G, Rao M, Mayor S. 2004. Nanoscale organization of multiple GPI-Anchored proteins in living cell membranes. Cell 116:577–589. DOI: https://doi.org/10.1016/S0092-8674(04)00167-9
-
(2004)
Cell
, vol.116
, pp. 577-589
-
-
Sharma, P.1
Varma, R.2
Sarasij, R.C.3
Ira, G.K.4
Krishnamoorthy, G.5
Rao, M.6
Mayor, S.7
-
59
-
-
0037168108
-
Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation
-
12408844
-
Sweeney ST, Davis GW. 2002. Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation. Neuron 36:403–416. DOI: https://doi.org/10.1016/S0896-6273 (02)01014-0, PMID: 12408844
-
(2002)
Neuron
, vol.36
, pp. 403-416
-
-
Sweeney, S.T.1
Davis, G.W.2
-
60
-
-
33751318469
-
Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion
-
Takada R, Satomi Y, Kurata T, Ueno N, Norioka S, Kondoh H, Takao T, Takada S. 2006. Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Developmental Cell 11:791–801. DOI: https://doi. org/10.1016/j.devcel.2006.10.003, PMID: 17141155
-
(2006)
Developmental Cell
, vol.11
, pp. 791-801
-
-
Takada, R.1
Satomi, Y.2
Kurata, T.3
Ueno, N.4
Norioka, S.5
Kondoh, H.6
Takao, T.7
Takada, S.8
-
61
-
-
84876533831
-
Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen
-
23449981
-
Vacaru AM, van den Dikkenberg J, Ternes P, Holthuis JC. 2013. Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen. Journal of Biological Chemistry 288:11520–11530. DOI: https://doi.org/10.1074/jbc.M113.460972, PMID: 23449981
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 11520-11530
-
-
Vacaru, A.M.1
van den Dikkenberg, J.2
Ternes, P.3
Holthuis, J.C.4
-
62
-
-
73249138376
-
Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion
-
19850864
-
van Zanten TS, Cambi A, Koopman M, Joosten B, Figdor CG, Garcia-Parajo MF. 2009. Hotspots of GPI-anchored proteins and integrin nanoclusters function as nucleation sites for cell adhesion. PNAS 106:18557– 18562. DOI: https://doi.org/10.1073/pnas.0905217106, PMID: 19850864
-
(2009)
PNAS
, vol.106
, pp. 18557-18562
-
-
van Zanten, T.S.1
Cambi, A.2
Koopman, M.3
Joosten, B.4
Figdor, C.G.5
Garcia-Parajo, M.F.6
-
63
-
-
0037449802
-
Drosophila egghead encodes a beta 1,4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac
-
12454022
-
Wandall HH, Pedersen JW, Park C, Levery SB, Pizette S, Cohen SM, Schwientek T, Clausen H. 2003. Drosophila egghead encodes a beta 1,4-mannosyltransferase predicted to form the immediate precursor glycosphingolipid substrate for brainiac. Journal of Biological Chemistry 278:1411–1414. DOI: https://doi.org/10.1074/jbc.C200619200, PMID: 12454022
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 1411-1414
-
-
Wandall, H.H.1
Pedersen, J.W.2
Park, C.3
Levery, S.B.4
Pizette, S.5
Cohen, S.M.6
Schwientek, T.7
Clausen, H.8
-
64
-
-
14244259481
-
Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo
-
15611100
-
Wandall HH, Pizette S, Pedersen JW, Eichert H, Levery SB, Mandel U, Cohen SM, Clausen H. 2005. Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo. Journal of Biological Chemistry 280:4858–4863. DOI: https://doi.org/10.1074/jbc.C400571200, PMID: 15611100
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 4858-4863
-
-
Wandall, H.H.1
Pizette, S.2
Pedersen, J.W.3
Eichert, H.4
Levery, S.B.5
Mandel, U.6
Cohen, S.M.7
Clausen, H.8
-
65
-
-
84888117780
-
Interaction of ganglioside GD3 with an EGF receptor sustains the self-renewal ability of mouse neural stem cells in vitro
-
24198336
-
Wang J, Yu RK. 2013. Interaction of ganglioside GD3 with an EGF receptor sustains the self-renewal ability of mouse neural stem cells in vitro. PNAS 110:19137–19142. DOI: https://doi.org/10.1073/pnas.1307224110, PMID: 24198336
-
(2013)
PNAS
, vol.110
, pp. 19137-19142
-
-
Wang, J.1
Yu, R.K.2
-
66
-
-
75549087039
-
Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1
-
19948478
-
Watanabe K, Nagaoka T, Lee JM, Bianco C, Gonzales M, Castro NP, Rangel MC, Sakamoto K, Sun Y, Callahan R, Salomon DS. 2009. Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1. The Journal of Cell Biology 187:343–353. DOI: https://doi.org/10.1083/jcb.200905105, PMID: 19948478
-
(2009)
The Journal of Cell Biology
, vol.187
, pp. 343-353
-
-
Watanabe, K.1
Nagaoka, T.2
Lee, J.M.3
Bianco, C.4
Gonzales, M.5
Castro, N.P.6
Rangel, M.C.7
Sakamoto, K.8
Sun, Y.9
Callahan, R.10
Salomon, D.S.11
-
67
-
-
34547937104
-
Growing dendrites and axons differ in their reliance on the secretory pathway
-
17719548
-
Ye B, Zhang Y, Song W, Younger SH, Jan LY, Jan YN. 2007. Growing dendrites and axons differ in their reliance on the secretory pathway. Cell 130:717–729. DOI: https://doi.org/10.1016/j.cell.2007.06.032, PMID: 17719548
-
(2007)
Cell
, vol.130
, pp. 717-729
-
-
Ye, B.1
Zhang, Y.2
Song, W.3
Younger, S.H.4
Jan, L.Y.5
Jan, Y.N.6
-
68
-
-
79951923158
-
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors
-
21321100
-
Yonamine I, Bamba T, Nirala NK, Jesmin N, Kosakowska-Cholody T, Nagashima K, Fukusaki E, Acharya JK, Acharya U. 2011. Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. The Journal of Cell Biology 192:557–567. DOI: https://doi.org/10.1083/jcb.201004098, PMID: 21321100
-
(2011)
The Journal of Cell Biology
, vol.192
, pp. 557-567
-
-
Yonamine, I.1
Bamba, T.2
Nirala, N.K.3
Jesmin, N.4
Kosakowska-Cholody, T.5
Nagashima, K.6
Fukusaki, E.7
Acharya, J.K.8
Acharya, U.9
-
69
-
-
66349103103
-
The role of glycosphingolipid metabolism in the developing brain
-
18845618
-
Yu RK, Nakatani Y, Yanagisawa M. 2009. The role of glycosphingolipid metabolism in the developing brain. Journal of Lipid Research 50:S440–S45. DOI: https://doi.org/10.1194/jlr.R800028-JLR200, PMID: 18845618
-
(2009)
Journal of Lipid Research
, vol.50
, pp. S440-S445
-
-
Yu, R.K.1
Nakatani, Y.2
Yanagisawa, M.3
-
70
-
-
4043154959
-
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
-
15166250
-
Zhai L, Chaturvedi D, Cumberledge S. 2004. Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. Journal of Biological Chemistry 279:33220–33227. DOI: https://doi.org/10.1074/jbc.M403407200, PMID: 15166250
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 33220-33227
-
-
Zhai, L.1
Chaturvedi, D.2
Cumberledge, S.3
-
71
-
-
84913549572
-
Exploring developmental and physiological functions of fatty acid and lipid variants through worm and fly genetics
-
25195508
-
Zhu H, Han M. 2014. Exploring developmental and physiological functions of fatty acid and lipid variants through worm and fly genetics. Annual Review of Genetics 48:119–148. DOI: https://doi.org/10.1146/annurev-genet-041814-095928, PMID: 25195508
-
(2014)
Annual Review of Genetics
, vol.48
, pp. 119-148
-
-
Zhu, H.1
Han, M.2
|