메뉴 건너뛰기




Volumn 9, Issue SEP, 2018, Pages

Melatonin in assisted reproductive technology: A pilot double-blind randomized placebo-controlled clinical trial

Author keywords

ART; Assisted reproductive technology; Clinical pregnancy; In vitro fertilization; IVF; Melatonin

Indexed keywords

ESTRADIOL; LUTEINIZING HORMONE; MELATONIN; PLACEBO; PROGESTERONE;

EID: 85055133367     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2018.00545     Document Type: Article
Times cited : (35)

References (27)
  • 1
    • 0035102208 scopus 로고    scopus 로고
    • Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings
    • Guerin P, El Mouatassim S, Menezo Y. Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings. Hum Reprod Update (2001) 7:175-89. doi: 10.1093/humupd/7.2.175
    • (2001) Hum Reprod Update , vol.7 , pp. 175-189
    • Guerin, P.1    El Mouatassim, S.2    Menezo, Y.3
  • 2
    • 40849139435 scopus 로고    scopus 로고
    • Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate
    • Tamura H, Takasaki A, Miwa I, Taniguchi K, Maekawa R, Asada H, et al. Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res. (2008) 44:280-7. doi: 10.1111/j.1600-079X.2007.00524.x
    • (2008) J Pineal Res. , vol.44 , pp. 280-287
    • Tamura, H.1    Takasaki, A.2    Miwa, I.3    Taniguchi, K.4    Maekawa, R.5    Asada, H.6
  • 5
    • 27344456070 scopus 로고    scopus 로고
    • Role of oxidative stress in female reproduction
    • Agarwal A, Gupta S, Sharma RK. Role of oxidative stress in female reproduction. Reprod Biol Endocrinol. (2005) 3:28. doi: 10.1186/1477-7827-3-28
    • (2005) Reprod Biol Endocrinol. , vol.3 , pp. 28
    • Agarwal, A.1    Gupta, S.2    Sharma, R.K.3
  • 6
    • 33646833292 scopus 로고    scopus 로고
    • The effect of melatonin treatment on the ovarian response of ewes to the ram effect
    • Abecia JA, Palacin I, Forcada F, Valares JA. The effect of melatonin treatment on the ovarian response of ewes to the ram effect. Domest Anim Endocrinol. (2006) 31:52-62. doi: 10.1016/j.domaniend.2005.09.003
    • (2006) Domest Anim Endocrinol. , vol.31 , pp. 52-62
    • Abecia, J.A.1    Palacin, I.2    Forcada, F.3    Valares, J.A.4
  • 7
    • 34548427517 scopus 로고    scopus 로고
    • Melatonin increases cleavage rate of porcine preimplantation embryos in vitro
    • Rodriguez-Osorio N, Kim I, Wang H, Kaya A, Memili E. Melatonin increases cleavage rate of porcine preimplantation embryos in vitro. J Pineal Res. (2007) 43:283-8. doi: 10.1111/j.1600-079X.2007.00475.x
    • (2007) J Pineal Res. , vol.43 , pp. 283-288
    • Rodriguez-Osorio, N.1    Kim, I.2    Wang, H.3    Kaya, A.4    Memili, E.5
  • 9
    • 84861705463 scopus 로고    scopus 로고
    • Sonographic monitoring of early follicle growth induced by melatonin implants in camels and the subsequent fertility
    • Dholpuria S, Vyas S, Purohit GN, Pathak KML. Sonographic monitoring of early follicle growth induced by melatonin implants in camels and the subsequent fertility. J Ultrasound (2012) 15:135-41. doi: 10.1016/j.jus.2012.02.008
    • (2012) J Ultrasound , vol.15 , pp. 135-141
    • Dholpuria, S.1    Vyas, S.2    Purohit, G.N.3    Pathak, K.M.L.4
  • 10
    • 84870296892 scopus 로고    scopus 로고
    • MT3 melatonin binding site, MT1 and MT2 melatonin receptors are present in oocyte, but only MT1 is present in bovine blastocyst produced in vitro
    • Sampaio R, Conceição S, Miranda M, Sampaio Lde F, Ohashi O. MT3 melatonin binding site, MT1 and MT2 melatonin receptors are present in oocyte, but only MT1 is present in bovine blastocyst produced in vitro. Reprod Biol Endocrinol. (2012) 10:103. doi: 10.1186/1477-7827-10-103
    • (2012) Reprod Biol Endocrinol. , vol.10 , pp. 103
    • Sampaio, R.1    Conceição, S.2    Miranda, M.3    Sampaio Lde, F.4    Ohashi, O.5
  • 11
    • 85027921954 scopus 로고    scopus 로고
    • Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems
    • Eryilmaz O, Devran A, Sarikaya E, Aksakal F, Mollamahmutoglu L, Cicek N. Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems. J Assist Reprod Genet. (2011) 28:815-20. doi: 10.1007/s10815-011-9604-y
    • (2011) J Assist Reprod Genet. , vol.28 , pp. 815-820
    • Eryilmaz, O.1    Devran, A.2    Sarikaya, E.3    Aksakal, F.4    Mollamahmutoglu, L.5    Cicek, N.6
  • 12
    • 84898846282 scopus 로고    scopus 로고
    • Oral melatonin supplementation improves oocyte and embryo quality in women undergoing in vitro fertilization-embryo transfer
    • Nishihara T, Hashimoto S, Ito K, Nakaoka Y, Matsumoto K, Hosoi Y, Morimoto Y. Oral melatonin supplementation improves oocyte and embryo quality in women undergoing in vitro fertilization-embryo transfer. Gynecol Endocrinol. (2014) 30, 359-62. doi: 10.3109/09513590.2013.879856
    • (2014) Gynecol Endocrinol. , vol.30 , pp. 359-362
    • Nishihara, T.1    Hashimoto, S.2    Ito, K.3    Nakaoka, Y.4    Matsumoto, K.5    Hosoi, Y.6    Morimoto, Y.7
  • 13
    • 0028947832 scopus 로고
    • Melatonin and steroids in human pre-ovulatory follicular fluid: Seasonal variations and granulosa cell steroid production
    • Yie SM, Brown GM, Liu GY, Collins JA, Daya S, Hughes EG, et al. Melatonin and steroids in human pre-ovulatory follicular fluid: seasonal variations and granulosa cell steroid production. Hum Reprod. (1995) 10:50-5. doi: 10.1093/humrep/10.1.50
    • (1995) Hum Reprod. , vol.10 , pp. 50-55
    • Yie, S.M.1    Brown, G.M.2    Liu, G.Y.3    Collins, J.A.4    Daya, S.5    Hughes, E.G.6
  • 14
    • 84877029464 scopus 로고    scopus 로고
    • Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro
    • Lord T, Nixon B, Jones KT, Aitken RJ. Melatonin prevents postovulatory oocyte aging in the mouse and extends the window for optimal fertilization in vitro. Biol Reprod. (2013) 88:67. doi: 10.1095/biolreprod.112.106450
    • (2013) Biol Reprod. , vol.88 , pp. 67
    • Lord, T.1    Nixon, B.2    Jones, K.T.3    Aitken, R.J.4
  • 15
    • 84891518945 scopus 로고    scopus 로고
    • Role of Myo-inositol and melatonin supplementation in follicular fluid of IVF patients with polycystic ovarian syndrome: A randomized controlled trial
    • Pacchiarotti A, Carlomagno G, Unfer V, Frati P, Pacchiarotti A, Prapas N. Role of Myo-inositol and melatonin supplementation in follicular fluid of IVF patients with polycystic ovarian syndrome: a randomized controlled trial. Clin Trialsgov. (2013).
    • (2013) Clin Trialsgov.
    • Pacchiarotti, A.1    Carlomagno, G.2    Unfer, V.3    Frati, P.4    Pacchiarotti, A.5    Prapas, N.6
  • 17
    • 79955159317 scopus 로고    scopus 로고
    • Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: A prospective, longitudinal, cohort study
    • Unfer V, Raffone E, Rizzo P, Buffo S. Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study. Gynaecol Endocrinol. (2011) 27:857-61. doi: 10.3109/09513590.2011.564687
    • (2011) Gynaecol Endocrinol. , vol.27 , pp. 857-861
    • Unfer, V.1    Raffone, E.2    Rizzo, P.3    Buffo, S.4
  • 18
    • 0037134681 scopus 로고    scopus 로고
    • The importance of pilot studies
    • Van Teijlingen E, Hundley V. The importance of pilot studies. Nurs Stand. (2002) 16:33-6. doi: 10.7748/ns.16.40.33.s1
    • (2002) Nurs Stand. , vol.16 , pp. 33-36
    • Van Teijlingen, E.1    Hundley, V.2
  • 19
    • 84940558360 scopus 로고    scopus 로고
    • A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): Study protocol
    • Fernando S, Osianlis T, Vollenhoven B, Wallace E, Rombauts L. A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): study protocol. BMJ Open (2014) 4:e005986. doi: 10.1136/bmjopen-2014-005986
    • (2014) BMJ Open , vol.4 , pp. e005986
    • Fernando, S.1    Osianlis, T.2    Vollenhoven, B.3    Wallace, E.4    Rombauts, L.5
  • 20
    • 20244380619 scopus 로고    scopus 로고
    • Treatment allocation by minimisation
    • Altman D, Bland J. Treatment allocation by minimisation. BMJ (2005) 330:843. doi: 10.1136/bmj.330.7495.843
    • (2005) BMJ , vol.330 , pp. 843
    • Altman, D.1    Bland, J.2
  • 21
    • 85053078260 scopus 로고    scopus 로고
    • The impact of melatonin on the sleep patterns of women undergoing IVF: A double blind RCT
    • Fernando S, Biggs SN, Horne RSC, Vollenhoven B, Lolatgis N, Hope N, et al. The impact of melatonin on the sleep patterns of women undergoing IVF: a double blind RCT. Hum Reprod Open (2017) 2017: hox027. doi: 10.1093/hropen/hox027
    • (2017) Hum Reprod Open , vol.2017 , pp. hox027
    • Fernando, S.1    Biggs, S.N.2    Horne, R.S.C.3    Vollenhoven, B.4    Lolatgis, N.5    Hope, N.6
  • 22
    • 10744224028 scopus 로고    scopus 로고
    • Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): Scavenging of free radicals and prevention of protein destruction
    • Ressmeyer A, Mayo J, Zelosko V, Sáinz R, Tan D, Poeggeler B, et al. Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction. Redox Rep. (2003) 8:205-13. doi: 10.1179/135100003225002709
    • (2003) Redox Rep. , vol.8 , pp. 205-213
    • Ressmeyer, A.1    Mayo, J.2    Zelosko, V.3    Sáinz, R.4    Tan, D.5    Poeggeler, B.6
  • 23
    • 84859733211 scopus 로고    scopus 로고
    • Melatonin pharmacokinetics following two different oral surge-sustained release doses in older adults
    • Gooneratne NS, Edwards AY, Zhou C, Cuellar N, Grandner MA, Barrett JS. Melatonin pharmacokinetics following two different oral surge-sustained release doses in older adults. J Pineal Res. (2012) 52:437-45. doi: 10.1111/j.1600-079X.2011.00958.x
    • (2012) J Pineal Res. , vol.52 , pp. 437-445
    • Gooneratne, N.S.1    Edwards, A.Y.2    Zhou, C.3    Cuellar, N.4    Grandner, M.A.5    Barrett, J.S.6
  • 24
    • 85032729104 scopus 로고    scopus 로고
    • Melatonin potentially acts directly on swine ovary by modulating granulosa cell function and angiogenesis
    • Basini G, Bussolati S, Ciccimarra R, Grasselli F. Melatonin potentially acts directly on swine ovary by modulating granulosa cell function and angiogenesis. Reprod Fertil Dev. (2017) 29:2305-12. doi: 10.1071/RD16513
    • (2017) Reprod Fertil Dev. , vol.29 , pp. 2305-2312
    • Basini, G.1    Bussolati, S.2    Ciccimarra, R.3    Grasselli, F.4
  • 25
    • 85014521699 scopus 로고    scopus 로고
    • Melatonin levels in follicular fluid as markers for IVF outcomes and predicting ovarian reserve
    • Tong J, Sheng S, Sun Y, Li H, Li WP, Zhang C, et al. Melatonin levels in follicular fluid as markers for IVF outcomes and predicting ovarian reserve. Reproduction (2017) 153:443-51. doi: 10.1530/REP-16-0641
    • (2017) Reproduction , vol.153 , pp. 443-451
    • Tong, J.1    Sheng, S.2    Sun, Y.3    Li, H.4    Li, W.P.5    Zhang, C.6
  • 26
    • 14844329898 scopus 로고    scopus 로고
    • Regression to the mean: What it is and how to deal with it
    • Barnett AG, Van Der Pols JC, Dobson AJ. Regression to the mean: what it is and how to deal with it. Int J Epidemiol. (2005) 34:215-20. doi: 10.1093/ije/dyh299
    • (2005) Int J Epidemiol. , vol.34 , pp. 215-220
    • Barnett, A.G.1    Van Der Pols, J.C.2    Dobson, A.J.3
  • 27
    • 84955640545 scopus 로고    scopus 로고
    • Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome
    • Pacchiarotti A, Carlomagno G, Antonini G, Pacchiarotti A. Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome. Gynecol Endocrinol. (2016) 32:69-73. doi: 10.3109/09513590.2015.1101444
    • (2016) Gynecol Endocrinol. , vol.32 , pp. 69-73
    • Pacchiarotti, A.1    Carlomagno, G.2    Antonini, G.3    Pacchiarotti, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.