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Volumn 32, Issue 1, 2016, Pages 69-73

Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome

Author keywords

Embryos quality; melatonin; myo inositol; oocytes quality; PCOS

Indexed keywords

ANTIOXIDANT; FOLIC ACID; INOSITOL; MELATONIN; VITAMIN B COMPLEX;

EID: 84955640545     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.3109/09513590.2015.1101444     Document Type: Article
Times cited : (78)

References (46)
  • 1
    • 68949213041 scopus 로고    scopus 로고
    • Homocysteine concentrations in follicular fluid are associated with poor oocyte and embryo qualities in polycystic ovary syndrome patients undergoing assisted reproduction
    • Berker B, Kaya C, Aytac R, Satiroglu H. Homocysteine concentrations in follicular fluid are associated with poor oocyte and embryo qualities in polycystic ovary syndrome patients undergoing assisted reproduction. Hum Reprod 2009; 24: 2293-302
    • (2009) Hum Reprod , vol.24 , pp. 2293-2302
    • Berker, B.1    Kaya, C.2    Aytac, R.3    Satiroglu, H.4
  • 2
    • 73249130618 scopus 로고    scopus 로고
    • Effect of follicular fluid oxidative stress on meiotic spindle formation in infertile women with polycystic ovarian syndrome
    • Chattopadhayay R, Ganesh A, Samanta J, et al. Effect of follicular fluid oxidative stress on meiotic spindle formation in infertile women with polycystic ovarian syndrome. Gynecol Obstet Invest 2010; 69: 197-202
    • (2010) Gynecol Obstet Invest , vol.69 , pp. 197-202
    • Chattopadhayay, R.1    Ganesh, A.2    Samanta, J.3
  • 3
    • 79955159317 scopus 로고    scopus 로고
    • Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: A prospective, longitudinal, cohort study
    • Unfer V, Raffone E, Rizzo P, Buffo S. Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study. Gynecol Endocrinol 2011; 27: 857-61
    • (2011) Gynecol Endocrinol , vol.27 , pp. 857-861
    • Unfer, V.1    Raffone, E.2    Rizzo, P.3    Buffo, S.4
  • 4
    • 78649351600 scopus 로고    scopus 로고
    • Predictive factors in in vitro fertilization (IVF): A systematic review and meta-Analysis
    • van Loendersloot LL, van Wely M, Limpens J, et al. Predictive factors in in vitro fertilization (IVF): a systematic review and meta-Analysis. Hum Reprod Update 2010; 16: 577-89
    • (2010) Hum Reprod Update , vol.16 , pp. 577-589
    • Van Loendersloot, L.L.1    Van Wely, M.2    Limpens, J.3
  • 5
    • 0035989371 scopus 로고    scopus 로고
    • Follicular fluid and serum concentrations of myo-inositol in patients undergoing IVF: Relationship with oocyte quality
    • Chiu TT, Rogers MS, Law EL, et al. Follicular fluid and serum concentrations of myo-inositol in patients undergoing IVF: relationship with oocyte quality. Hum Reprod 2002; 17: 1591-6
    • (2002) Hum Reprod , vol.17 , pp. 1591-1596
    • Chiu, T.T.1    Rogers, M.S.2    Law, E.L.3
  • 6
    • 0037323672 scopus 로고    scopus 로고
    • Effects of myo-inositol on the in-vitro maturation and subsequent development of mouse oocytes
    • Chiu TT, Rogers MS, Briton-Jones C, Haines C. Effects of myo-inositol on the in-vitro maturation and subsequent development of mouse oocytes. Hum Reprod 2003; 18: 408-16
    • (2003) Hum Reprod , vol.18 , pp. 408-416
    • Chiu, T.T.1    Rogers, M.S.2    Briton-Jones, C.3    Haines, C.4
  • 7
    • 67649084063 scopus 로고    scopus 로고
    • Melatonin and the ovary: Physiological and pathophysiological implications
    • Tamura H, Nakamura Y, Korkmaz A, et al. Melatonin and the ovary: physiological and pathophysiological implications. Fertil Steril 2009; 92: 328-43
    • (2009) Fertil Steril , vol.92 , pp. 328-343
    • Tamura, H.1    Nakamura, Y.2    Korkmaz, A.3
  • 8
    • 67349165861 scopus 로고    scopus 로고
    • Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial
    • Papaleo E, Unfer V, Baillargeon JP, et al. Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Fertil Steril 2009; 91: 1750-4
    • (2009) Fertil Steril , vol.91 , pp. 1750-1754
    • Papaleo, E.1    Unfer, V.2    Baillargeon, J.P.3
  • 9
    • 77955816584 scopus 로고    scopus 로고
    • Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial
    • Rizzo P, Raffone E, Benedetto V. Effect of the treatment with myo-inositol plus folic acid plus melatonin in comparison with a treatment with myo-inositol plus folic acid on oocyte quality and pregnancy outcome in IVF cycles. A prospective, clinical trial. Eur Rev Med Pharmacol Sci 2010; 14: 555-61
    • (2010) Eur Rev Med Pharmacol Sci , vol.14 , pp. 555-561
    • Rizzo, P.1    Raffone, E.2    Benedetto, V.3
  • 10
    • 79953171125 scopus 로고    scopus 로고
    • The adapter protein APPL1 links FSH receptor to inositol 1,4,5-Trisphosphate production and is implicated in intracellular Ca (2+) mobilization
    • Thomas RM, Nechamen CA, Mazurkiewicz JE, et al. The adapter protein APPL1 links FSH receptor to inositol 1,4,5-Trisphosphate production and is implicated in intracellular Ca (2+) mobilization. Endocrinology 2011; 152: 1691-701
    • (2011) Endocrinology , vol.152 , pp. 1691-1701
    • Thomas, R.M.1    Nechamen, C.A.2    Mazurkiewicz, J.E.3
  • 11
    • 79953755954 scopus 로고    scopus 로고
    • FSH and its second messenger cAMP stimulate the transcription of human anti-Mullerian hormone in cultured granulosa cells
    • Taieb J, Grynberg M, Pierre A, et al. FSH and its second messenger cAMP stimulate the transcription of human anti-Mullerian hormone in cultured granulosa cells. Mol Endocrinol 2011; 25: 645-55
    • (2011) Mol Endocrinol , vol.25 , pp. 645-655
    • Taieb, J.1    Grynberg, M.2    Pierre, A.3
  • 12
    • 36749103313 scopus 로고    scopus 로고
    • Randomized, double blind placebo-controlled trial: Effects of myo-inositol on ovarian function and metabolic factors in women with PCOS
    • Gerli S, Papaleo E, Ferrari A, Di Renzo GC. Randomized, double blind placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS. Eur Rev Med Pharmacol Sci 2007; 11: 347-54
    • (2007) Eur Rev Med Pharmacol Sci , vol.11 , pp. 347-354
    • Gerli, S.1    Papaleo, E.2    Ferrari, A.3    Di Renzo, G.C.4
  • 13
    • 37149045934 scopus 로고    scopus 로고
    • Myo-inositol in patients with polycystic ovary syndrome: A novel method for ovulation induction
    • Papaleo E, Unfer V, Baillargeon JP, et al. Myo-inositol in patients with polycystic ovary syndrome: a novel method for ovulation induction. Gynecol Endocrinol 2007; 23: 700-3
    • (2007) Gynecol Endocrinol , vol.23 , pp. 700-703
    • Papaleo, E.1    Unfer, V.2    Baillargeon, J.P.3
  • 14
  • 15
    • 7444228554 scopus 로고    scopus 로고
    • Evaluation of the role of melatonin in formalin-induced pain response in mice
    • Ray M, Mediratta PK, Mahajan P, Sharma KK. Evaluation of the role of melatonin in formalin-induced pain response in mice. Indian J Med Sci 2004; 58: 122-30
    • (2004) Indian J Med Sci , vol.58 , pp. 122-130
    • Ray, M.1    Mediratta, P.K.2    Mahajan, P.3    Sharma, K.K.4
  • 16
    • 34848928810 scopus 로고    scopus 로고
    • Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: Hypothesis and significance
    • Tan DX, Manchester LC, Terron MP, et al. Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: hypothesis and significance. J Pineal Res 2007; 43: 317-20
    • (2007) J Pineal Res , vol.43 , pp. 317-320
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3
  • 17
    • 79961014729 scopus 로고    scopus 로고
    • Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: A double blind trial
    • Ciotta L, Stracquadanio M, Pagano I, et al. Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: a double blind trial. Eur Rev Med Pharmacol Sci 2011; 15: 509-14
    • (2011) Eur Rev Med Pharmacol Sci , vol.15 , pp. 509-514
    • Ciotta, L.1    Stracquadanio, M.2    Pagano, I.3
  • 18
    • 34848851871 scopus 로고    scopus 로고
    • Efficacy of a combined protocol of urinary and recombinant follicle-stimulating hormone used for ovarian stimulation of patients undergoing ICSI cycle
    • Pacchiarotti A, Aragona C, Gaglione R, Selman H. Efficacy of a combined protocol of urinary and recombinant follicle-stimulating hormone used for ovarian stimulation of patients undergoing ICSI cycle. J Assist Reprod Genet 2007; 24: 400-5
    • (2007) J Assist Reprod Genet , vol.24 , pp. 400-405
    • Pacchiarotti, A.1    Aragona, C.2    Gaglione, R.3    Selman, H.4
  • 19
    • 77957198585 scopus 로고    scopus 로고
    • Ovarian stimulation protocols based on follicle-stimulating hormone glycosylation pattern: Impact on oocyte quality and clinical outcome
    • Selman H, Pacchiarotti A, El-Danasouri I. Ovarian stimulation protocols based on follicle-stimulating hormone glycosylation pattern: impact on oocyte quality and clinical outcome. Fertil Steril 2010; 94: 1782-6
    • (2010) Fertil Steril , vol.94 , pp. 1782-1786
    • Selman, H.1    Pacchiarotti, A.2    El-Danasouri, I.3
  • 21
    • 70450220325 scopus 로고    scopus 로고
    • Melatonin and human reproduction: Shedding light on the darkness hormone
    • Srinivasan V, Spence WD, Pandi-Perumal SR, et al. Melatonin and human reproduction: shedding light on the darkness hormone. Gynecol Endocrinol 2009; 25: 779-85
    • (2009) Gynecol Endocrinol , vol.25 , pp. 779-785
    • Srinivasan, V.1    Spence, W.D.2    Pandi-Perumal, S.R.3
  • 23
    • 0023394477 scopus 로고
    • In vitro steroidogenesis by primary to antral follicles in the hamster during the periovulatory period: Effects of follicle-stimulating hormone, luteinizing hormone, and prolactin
    • Roy SK, Greenwald GS. In vitro steroidogenesis by primary to antral follicles in the hamster during the periovulatory period: effects of follicle-stimulating hormone, luteinizing hormone, and prolactin. Biol Reprod 1987; 37: 39-46
    • (1987) Biol Reprod , vol.37 , pp. 39-46
    • Roy, S.K.1    Greenwald, G.S.2
  • 24
    • 65649089522 scopus 로고    scopus 로고
    • Morphogenesis of polycystic ovaries as assessed by pituitary-ovarian androgenic function
    • Mori T, Nonoguchi K, Watanabe H, et al. Morphogenesis of polycystic ovaries as assessed by pituitary-ovarian androgenic function. Reprod Biomed Online 2009; 18: 635-43
    • (2009) Reprod Biomed Online , vol.18 , pp. 635-643
    • Mori, T.1    Nonoguchi, K.2    Watanabe, H.3
  • 26
    • 68949175354 scopus 로고    scopus 로고
    • Melatonin promotes the cumulus-oocyte complexes quality of vitrified-Thawed murine ovaries; With increased mean number of follicles survival and ovary size following heterotopic transplantation
    • Hemadi M, Abolhassani F, Akbari M, et al. Melatonin promotes the cumulus-oocyte complexes quality of vitrified-Thawed murine ovaries; with increased mean number of follicles survival and ovary size following heterotopic transplantation. Eur J Pharmacol 2009; 618: 84-90
    • (2009) Eur J Pharmacol , vol.618 , pp. 84-90
    • Hemadi, M.1    Abolhassani, F.2    Akbari, M.3
  • 27
    • 0032880735 scopus 로고    scopus 로고
    • Melatonin receptor mRNA expression in human granulosa cells
    • Niles LP, Wang J, Shen L, et al. Melatonin receptor mRNA expression in human granulosa cells. Mol Cell Endocrinol 1999; 156: 107-10
    • (1999) Mol Cell Endocrinol , vol.156 , pp. 107-110
    • Niles, L.P.1    Wang, J.2    Shen, L.3
  • 28
    • 0034748339 scopus 로고    scopus 로고
    • Direct action of melatonin in human granulosa-luteal cells
    • Woo MM, Tai CJ, Kang SK, et al. Direct action of melatonin in human granulosa-luteal cells. J Clin Endocrinol Metab 2001; 86: 4789-97
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4789-4797
    • Woo, M.M.1    Tai, C.J.2    Kang, S.K.3
  • 29
    • 0026356114 scopus 로고
    • Development of follicles in the mammalian ovary
    • Hirshfield AN. Development of follicles in the mammalian ovary. Int Rev Cytol 1991; 124: 43-101
    • (1991) Int Rev Cytol , vol.124 , pp. 43-101
    • Hirshfield, A.N.1
  • 30
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • Reppert SM, Weaver DR, Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 1994; 13: 1177-85
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 31
    • 0028127924 scopus 로고
    • Current status of the hypothesis that mammalian ovulation is comparable to an inflammatory reaction
    • Espey LL. Current status of the hypothesis that mammalian ovulation is comparable to an inflammatory reaction. Biol Reprod 1994; 50: 233-8
    • (1994) Biol Reprod , vol.50 , pp. 233-238
    • Espey, L.L.1
  • 32
    • 65649148323 scopus 로고    scopus 로고
    • Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: A double-blind trial
    • Costantino D, Minozzi G, Minozzi E, Guaraldi C. Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial. Eur Rev Med Pharmacol Sci 2009; 13: 105-10
    • (2009) Eur Rev Med Pharmacol Sci , vol.13 , pp. 105-110
    • Costantino, D.1    Minozzi, G.2    Minozzi, E.3    Guaraldi, C.4
  • 33
    • 80054001658 scopus 로고    scopus 로고
    • The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine, and clinical parameters in polycystic ovary syndrome
    • Minozzi M, Costantino D, Guaraldi C, Unfer V. The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine, and clinical parameters in polycystic ovary syndrome. Gynecol Endocrinol 2011; 27: 920-4
    • (2011) Gynecol Endocrinol , vol.27 , pp. 920-924
    • Minozzi, M.1    Costantino, D.2    Guaraldi, C.3    Unfer, V.4
  • 34
    • 0141851108 scopus 로고    scopus 로고
    • Micronutrient deficiencies in developing and affluent countries
    • Diaz JR, de las Cagigas A, Rodriguez R. Micronutrient deficiencies in developing and affluent countries. Eur J Clin Nutr 2003; 57: S70-2
    • (2003) Eur J Clin Nutr , vol.57 , pp. S70-S72
    • Diaz, J.R.1    De Las Cagigas, A.2    Rodriguez, R.3
  • 35
    • 77957158189 scopus 로고    scopus 로고
    • Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: Structure, synthesis, and development of probes for studying biological activity
    • Best MD, Zhang H, Prestwich GD. Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: structure, synthesis, and development of probes for studying biological activity. Nat Prod Rep 2010; 27: 1403-30
    • (2010) Nat Prod Rep , vol.27 , pp. 1403-1430
    • Best, M.D.1    Zhang, H.2    Prestwich, G.D.3
  • 36
    • 77953762012 scopus 로고    scopus 로고
    • Translation of the phosphoinositide code by PI effectors
    • Kutateladze TG. Translation of the phosphoinositide code by PI effectors. Nat Chem Biol 2010; 6: 507-13
    • (2010) Nat Chem Biol , vol.6 , pp. 507-513
    • Kutateladze, T.G.1
  • 37
    • 0029789881 scopus 로고    scopus 로고
    • Transient release of calcium from inositol 1,4,5-Trisphosphate-specific stores regulates mouse preimplantation development
    • Stachecki JJ, Armant DR. Transient release of calcium from inositol 1,4,5-Trisphosphate-specific stores regulates mouse preimplantation development. Development 1996; 122: 2485-96
    • (1996) Development , vol.122 , pp. 2485-2496
    • Stachecki, J.J.1    Armant, D.R.2
  • 38
    • 0036798058 scopus 로고    scopus 로고
    • Inositol 1,4,5-Trisphosphate receptor function in human oocytes: Calcium responses and oocyte activation-related phenomena induced by photolytic release of InsP(3) are blocked by a specific antibody to the type i receptor
    • Goud PT, Goud AP, Leybaert L, et al. Inositol 1,4,5-Trisphosphate receptor function in human oocytes: calcium responses and oocyte activation-related phenomena induced by photolytic release of InsP(3) are blocked by a specific antibody to the type I receptor. Mol Hum Reprod 2002; 8: 912-18
    • (2002) Mol Hum Reprod , vol.8 , pp. 912-918
    • Goud, P.T.1    Goud, A.P.2    Leybaert, L.3
  • 39
    • 0027081786 scopus 로고
    • A correlation of the outcome of clinical in vitro fertilization with the inositol content and embryotrophic properties of human serum
    • Chiu TT, Tam PP. A correlation of the outcome of clinical in vitro fertilization with the inositol content and embryotrophic properties of human serum. J Assist Reprod Genet 1992; 9: 524-30
    • (1992) J Assist Reprod Genet , vol.9 , pp. 524-530
    • Chiu, T.T.1    Tam, P.P.2
  • 40
    • 40849139435 scopus 로고    scopus 로고
    • Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate
    • Tamura H, Takasaki A, Miwa I, et al. Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res 2008; 44: 280-7
    • (2008) J Pineal Res , vol.44 , pp. 280-287
    • Tamura, H.1    Takasaki, A.2    Miwa, I.3
  • 41
    • 79955130777 scopus 로고    scopus 로고
    • Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial
    • Unfer V, Carlomagno G, Rizzo P, et al. Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Eur Rev Med Pharmacol Sci 2011; 15: 452-7
    • (2011) Eur Rev Med Pharmacol Sci , vol.15 , pp. 452-457
    • Unfer, V.1    Carlomagno, G.2    Rizzo, P.3
  • 42
    • 44449149669 scopus 로고    scopus 로고
    • Less is more: Increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization
    • Pal L, Jindal S, Witt BR, Santoro N. Less is more: increased gonadotropin use for ovarian stimulation adversely influences clinical pregnancy and live birth after in vitro fertilization. Fertil Steril 2008; 89: 1694-701
    • (2008) Fertil Steril , vol.89 , pp. 1694-1701
    • Pal, L.1    Jindal, S.2    Witt, B.R.3    Santoro, N.4
  • 43
    • 0028921511 scopus 로고
    • Metabolic regulation of androgen production by human thecal cells in vitro
    • Nahum R, Thong KJ, Hillier SG. Metabolic regulation of androgen production by human thecal cells in vitro. Hum Reprod 1995; 10: 75-81
    • (1995) Hum Reprod , vol.10 , pp. 75-81
    • Nahum, R.1    Thong, K.J.2    Hillier, S.G.3
  • 44
    • 0021691796 scopus 로고
    • Hormonal regulation of the differentiation of cultured ovarian granulosa cells
    • Hsueh AJ, Adashi EY, Jones PB, Welsh TH Jr. Hormonal regulation of the differentiation of cultured ovarian granulosa cells. Endocr Rev 1984; 5: 76-127
    • (1984) Endocr Rev , vol.5 , pp. 76-127
    • Hsueh, A.J.1    Adashi, E.Y.2    Jones, P.B.3    Welsh, T.H.4
  • 45
    • 0029202298 scopus 로고
    • Ovarian cell differentiation: A cascade of multiple hormones, cellular signals, and regulated genes
    • Richards JS, Fitzpatrick SL, Clemens JW, et al. Ovarian cell differentiation: a cascade of multiple hormones, cellular signals, and regulated genes. Recent Prog Horm Res 1995; 50: 223-54
    • (1995) Recent Prog Horm Res , vol.50 , pp. 223-254
    • Richards, J.S.1    Fitzpatrick, S.L.2    Clemens, J.W.3
  • 46
    • 84884176432 scopus 로고    scopus 로고
    • Simultaneous administration of human acidic and recombinant less acidic follicle-stimulating hormone for ovarian stimulation improves oocyte and embryo quality, and clinical outcome in patients with repeated IVF failures
    • Selman H, Pacchiarotti A, Rinaldi L, et al. Simultaneous administration of human acidic and recombinant less acidic follicle-stimulating hormone for ovarian stimulation improves oocyte and embryo quality, and clinical outcome in patients with repeated IVF failures. Eur Rev Med Pharmacol Sci 2013; 17: 1814-19
    • (2013) Eur Rev Med Pharmacol Sci , vol.17 , pp. 1814-1819
    • Selman, H.1    Pacchiarotti, A.2    Rinaldi, L.3


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