Estimating relative efficacy in acute postoperative pain: Network meta-analysis is consistent with indirect comparison to placebo alone

Pain

Volumn 159, Issue 11, 2018, Pages 2234-2244

  Andrew Moore, R ^a   Derry, Sheena ^a   Wiffen, Philip J ^a   Banerjee, Samik ^b   Karan, Rajesh ^c   Glimm, Ekkehard ^c   Wiksten, Anna ^c   Aldington, Dominic ^d   Eccleston, Christopher ^e,f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NOVARTIS HEALTHCARE PVT LTD   (India)

^c NOVARTIS PHARMA AG   (Switzerland)

^d ROYAL HAMPSHIRE COUNTY HOSPITAL   (United Kingdom)

^e University of Bath   (United Kingdom)

^f GHENT UNIVERSITY   (Belgium)

Author keywords

Cochrane; Network meta analysis; Postoperative pain; Systematic review

Indexed keywords

ANALGESIC AGENT; PLACEBO; ACETYLSALICYLIC ACID; CELECOXIB; CODEINE; DICLOFENAC; DIPYRONE; ETODOLAC; IBUPROFEN; KETOPROFEN; NAPROXEN; OXYCODONE; PARACETAMOL;

ACUTE DISEASE; ANALGESIA; ARTICLE; COMPARATIVE STUDY; DENTAL SURGERY; DRUG EFFICACY; ELECTIVE SURGERY; EPISIOTOMY; GYNECOLOGIC SURGERY; HUMAN; NETWORK META-ANALYSIS; ORTHOPEDIC SURGERY; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SYSTEMATIC REVIEW; TEMPORAL ANALYSIS; THIRD MOLAR; VISUAL ANALOG SCALE; BUNIONECTOMY; CESAREAN SECTION; COCHRANE LIBRARY; COMBINATION CHEMOTHERAPY; EFFECT SIZE; HERNIOPLASTY; MENISCECTOMY; NUMBERS NEEDED TO TREAT; ORAL SURGERY; SURGICAL PATIENT; SYSTEMATIC REVIEW (TOPIC); TONSILLECTOMY; TOOTH EXTRACTION; UROLOGIC SURGERY; ADULT; FEMALE; MALE; PSYCHOLOGY; RETROSPECTIVE STUDY; TREATMENT OUTCOME;

ADULT; ANALGESICS; FEMALE; HUMANS; MALE; NETWORK META-ANALYSIS; PAIN, POSTOPERATIVE; PLACEBOS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 85055075844     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000001322     Document Type: Article

References (55)

1. AlBalawi Z, McAlister FA, Thorlund K, Wong M, Wetterslev J. Random error in cardiovascular meta-analyses: how common are false positive and false negative results? Int J Cardiol 2013;168:1102-7.
2. Barden J, Derry S, McQuay HJ, Moore RA. Bias from industry trial funding? A framework, a suggested approach, and a negative result. PAIN 2006;121:207-18.
3. Barden J, Edwards JE, McQuay HJ, Andrew Moore R. Pain and analgesic response after third molar extraction and other postsurgical pain. PAIN 2004;107:86-90.
4. Caldwell DM, Ades AE, Higgins JP. Simultaneous comparison of multiple treatments: combining direct and indirect evidence. BMJ 2005;331: 897-900.
5. Collins SL, Edwards J, Moore RA, Smith LA, McQuay HJ. Seeking a simple measure of analgesia for mega-trials: is a single global assessment good enough? PAIN 2001;91:189-94.
6. Cooper SA. Single-dose analgesic studies: the upside and downside of assay sensitivity. In: Max MB, Portenoy RK, Laska EM, editors. The design of analgesic clinical trials. Advances in pain research and therapy. Vol. 18. New York: Raven Press, 1991. p. 117-24.
7. Cooper TE, Heathcote LC, Clinch J, Gold JI, Howard R, Lord SM, Schechter N, Wood C, Wiffen PJ. Antidepressants for chronic non-cancer pain in children and adolescents. Cochrane Database Syst Rev 2017;8:CD012535.
8. da Costa BR, Reichenbach S, Keller N, Nartey L, Wandel S, Jüni P, Trelle S. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet 2017;390:e21-e33.
9. Dechartres A, Altman DG, Trinquart L, Boutron I, Ravaud P. Association between analytic strategy and estimates of treatment outcomes in meta-analyses. JAMA 2014;312:623-30.
10. Dechartres A, Trinquart L, Boutron I, Ravaud P. Influence of trial sample size on treatment effect estimates: meta-epidemiological study. BMJ 2013;346:f2304.
11. Derry S, Cooper TE, Phillips T. Single fixed-dose oral dexketoprofen plus tramadol for acute postoperative pain in adults. Cochrane Database Syst Rev 2016;9:CD012232.
12. Eccleston C, Cooper TE, Fisher E, Anderson B, Wilkinson NM. Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. Cochrane Database Syst Rev 2017;8: CD012537.
13. Effective Practice and Organisation of Care (EPOC). 23. Worksheets for preparing a summary of findings using GRADE. Resources for review authors. Oslo: Norwegian Knowledge Centre for the Health Services, 2015. Available at: epoc.cochrane.org/epoc-specific-resources-review-authors. Accessed January 19, 2018.
14. Gaskell H, Derry S, Wiffen PJ, Moore RA. Single dose oral ketoprofen or dexketoprofenfor acute postoperative pain in adults. Cochrane Database Syst Rev 2017;5:CD007355.
15. Häuser W, Bartram-Wunn E, Bartram C, Reinecke H, Tölle T. Systematic review: placebo response in drug trials of fibromyalgia syndrome and painful peripheral diabetic neuropathy-magnitude and patient-related predictors. PAIN 2011;152:1709-17.
16. Hearn L, Derry S, Moore RA. Single dose dipyrone (metamizole) for acute postoperative pain in adults. Cochrane Database Syst Rev 2016;4: CD011421.
17. Hospital episode statistics, admitted patient care-England, 2014-15. NHS Digital, 2015. Available at: https://digital.nhs.uk/catalogue/PUB19124. Accessed March 1, 2018.
18. Houde RW, Wallenstein SL, Rogers A. Clinical pharmacology of analgesics. 1. A method of assaying analgesic effect. Clin Pharmacol Ther 1960;1:163-74.
19. IntHout J, Ioannidis JP, Borm GF, Goeman JJ. Small studies are more heterogeneous than large ones: a meta-meta-analysis. J Clin Epidemiol 2015;68:860-9.
20. Jadad AR, McQuay HJ. A high-yield strategy to identify randomized controlled trials for systematic reviews. Online J Curr Clin Trials 1993;Doc No 33. PMID: 8306000.
21. Jansen JP, Fleurence R, Devine B, Itzler R, Barrett A, Hawkins N, Lee K, Boersma C, Annemans L, Cappelleri JC. Interpreting indirect treatment comparisons and network meta-analysis for health-care decision making: report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: part 1. Value Health 2011;14: 417-28.
22. Katz J, Finnerup NB, Dworkin RH. Clinical trial outcome in neuropathic pain: relationship to study characteristics. Neurology 2008;70:263-72.
23. Li T, Puhan MA, Vedula SS, Singh S, Dickersin K. Ad Hoc Network Meta-analysis Methods Meeting Working Group. Network meta-analysis-highly attractive but more methodological research is needed. BMC Med 2011; 9:79.
24. Li Wan Po A, Petersen B. How high should total pain-relief score be to obviate the need for analgesic remedication in acute pain? Estimation using signal detection theory and individual-patient meta-analysis. J Clin Pharm Ther 2006;31:161-5.
25. Lu G, Ades AE. Combination of direct and indirect evidence in mixed treatment comparisons. Stat Med 2004;23:3105-24.
26. Martinez V, Beloeil H, Marret E, Fletcher D, Ravaud P, Trinquart L. Non-opioid analgesics in adults after major surgery: systematic review with network meta-analysis of randomized trials. Br J Anaesth 2017;118: 22-31.
27. McCullagh P, Nelder JA. Quasi-likelihood functions. In: McCullagh P, Nelder JA, editors. Generalized linear models. London: Chapman and Hall, 1989. p. 323-56.
28. McQuay HJ, Derry S, Eccleston C, Wiffen PJ, Moore RA. Evidence for analgesic effect in acute pain-50 years on. PAIN 2012;153:1364-7.
29. McQuay HJ, Moore RA. Dose-response indirect comparisons of different doses of aspirin, ibuprofen and paracetamol (acetaminophen) in analgesic studies. Br J Clin Pharmacol 2007;63:271-8.
30. Mhuircheartaigh RJ, Moore RA, McQuay HJ. Analysis of individual patient data from clinical trials: epidural morphine for postoperative pain. Br J Anaesth 2009;103:874-81.
31. Mills EJ, Thorlund K, Ioannidis JP. Demystifying trial networks and network meta-analysis. BMJ 2013;346:f2914.
32. Moore A, McQuay H, Gavaghan D. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics. PAIN 1996;66:229-37.
33. Moore A, McQuay H, Gavaghan D. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: verification from independent data. PAIN 1997;69:127-30.
34. Moore A, Moore O, McQuay H, Gavaghan D. Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics: use of pain intensity and visual analogue scales. PAIN 1997;69:311-5.
35. Moore RA, Barden J, Derry S, McQuay HJ. Managing Potential publication bias. In: McQuay HJ, Kalso E, Moore RA, editors. Systematic reviews in pain research: methodology refined. Seattle: IASP Press, 2008. p. 15-23.
36. Moore RA, Derry S, Aldington D, Wiffen PJ. Adverse events associated with single dose oral analgesics for acute postoperative pain in adults-an overview of Cochrane reviews. Cochrane Database Syst Rev 2015;10:CD011407.
37. Moore RA, Derry S, Aldington D, Wiffen PJ. Single dose oral analgesics for acute postoperative pain in adults-an overview of Cochrane reviews. Cochrane Database Syst Rev 2015;9:CD008659.
38. Moore RA, Edwards JE, McQuay HJ. Acute pain: individual patient meta-analysis shows the impact of different ways of analysing and presenting results. PAIN 2005;116:322-31.
39. Moore RA, Gavaghan D, Tramèr MR, Collins SL, McQuay HJ. Size is everything-large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects. PAIN 1998;78:209-16.
40. Moore RA, McQuay HJ. Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics. PAIN 1997;69:287-94.
41. Moore RA, Straube S, Aldington D. Pain measures and cut-offs-"no worse than mild pain" as a simple, universal outcome. Anaesthesia 2013; 68:400-12.
42. Moore RA, Straube S, Paine J, Derry S, McQuay HJ. Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction. PAIN 2011;152:982-9.
43. Nguyen TL, Collins GS, Lamy A, Devereaux PJ, Daurès JP, Landais P, Le Manach Y, Le Manach Y. Simple randomization did not protect against bias in smaller trials. J Clin Epidemiol 2017;84:105-13.
44. Nüesch E, Häuser W, Bernardy K, Barth J, Jüni P. Comparative efficacy of pharmacological and non-pharmacological interventions in fibromyalgia syndrome: network meta-analysis. Ann Rheum Dis 2013;72:955-62.
45. Pitz M, Cheang M, Bernstein CN. Defining the predictors of the placebo response in irritable bowel syndrome. Clin Gastroenterol Hepatol 2005;3: 237-47.
46. Quessy SN, Rowbotham MC. Placebo response in neuropathic pain trials. PAIN 2008;138:479-83.
47. Salanti G, Higgins J, Ades AE, Ioannidis JP. Evaluation of networks of randomized trials. Stat Methods Med Res 2008;17:279-301.
48. Schnabel A, Thyssen NM, Goeters C, Zheng H, Zahn PK, Van Aken H, Pogatzki-Zahn EM. Age-and procedure-specific differences of epidural analgesia in children-a database analysis. Pain Med 2015;16:544-53.
49. Song F, Altman DG, Glenny AM, Deeks JJ. Validity of indirect comparison for estimating efficacy of competing interventions: empirical evidence from published meta-analyses. BMJ 2003;326:472.
50. Thorlund K, Imberger G, Walsh M, Chu R, Gluud C, Wetterslev J, Guyatt G, Devereaux PJ, Thabane L. The numberof patients and events required to limit the risk of overestimation of intervention effects in meta-analysis-a simulation study. PLoS One 2011;6:e25491.
51. Thorlund K, Toor K, Wu P, Chan K, Druyts E, Ramos E, Bhambri R, Donnet A, Stark R, Goadsby PJ. Comparative tolerability oftreatments for acute migraine: a network meta-analysis. Cephalalgia 2017;37:965-78.
52. Tuttle AH, Tohyama S, Ramsay T, Kimmelman J, Schweinhardt P, Bennett GJ, Mogil JS. Increasing placebo responses over time in U.S. clinical trials of neuropathic pain. PAIN 2015;156:2616-26.
53. van Walsem A, Pandhi S, Nixon RM, Guyot P, Karabis A, Moore RA. Relative benefit-risk comparing diclofenac to other traditional non-steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors in patients with osteoarthritis or rheumatoid arthritis: a network meta-analysis. Arthritis Res Ther 2015;17:66.
54. Vase L, Vollert J, Finnerup NB, Miao X, Atkinson G, Marshall S, Nemeth R, Lange B, Liss C, Price DD, Maier C, Jensen TS, Segerdahl M. Predictors of the placebo analgesia response in randomized controlled trials of chronic pain: a meta-analysis of the individual data from nine industrially sponsored trials. PAIN 2015;156: 1795-802.
55. Wiffen PJ, Cooper TE, Anderson AK, Gray AL, Grégoire MC, Ljungman G, Zernikow B. Opioids for cancer-related pain in children and adolescents. Cochrane Database Syst Rev 2017;7:CD012564.