Deriving dichotomous outcome measures from continuous data in randomised controlled trials of analgesics

Pain

Volumn 66, Issue 2-3, 1996, Pages 229-237

  Moore, Andrew ^a,c   McQuay, Henry ^a   Gavaghan, David ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Pain Relief Unit   (United Kingdom)

Author keywords

Analgesics; Dichotomous information; Meta analysis; Randomised controlled trials

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; BROMFENAC; BUPRENORPHINE; CODEINE; DEXTROPROPOXYPHENE; DIHYDROCODEINE; KETOROLAC; MEPTAZINOL; MORPHINE; PARACETAMOL; PETHIDINE; ZOMEPIRAC;

ANALGESIA; ANALGESIC ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFICACY; HUMAN; META ANALYSIS; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0030220659     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3959(96)03032-1     Document Type: Article

References (23)

1. Bullingham R.E.S., McQuay H.J., Moore R.A., Weir L. An oral buprenorphine and paracetamol combination compared with paracetamol alone; a single dose double-blind postoperative study. Br. J. Clin. Pharmacol. 12:1981;863-867.
2. Carroll D., Frankland T., Nagle C., McQuay H. Oral bromfenac 10 and 25 mg compared with sublingual buprenorphine 0.2 and 0.4 mg for postoperative pain relief. Br. J. Anaesth. 71:1993;814-817.
3. Chalmers I. `Applying overviews and meta-analysis at the bedside': discussion. J. Clin. Epidemiol. 48:1995;67-70.
4. Cook R.J., Sackett D.L. The number needed to treat: a clinically useful measure of treatment effect. Br. Med. J. 310:1995;452-454.
5. Dudewicz, E.J. and Mishra, S.M., Modern Mathematical Statistics, Wiley, New York, 1988.
6. Easterbrook P., Berlin J. Meta-analysis. Lancet. 341:1993;965.
7. Evans, F.J., The placebo response in pain reduction. In: J.J. Bonica (Ed.), Advances in Neurology, Vol. 4, Raven Press, New York, 1974, pp. 289-296.
8. Evans P.J.D., McQuay H.J., Rolfe M., O'Sullivan G., Bullingham R.E.S., Moore R.A. Zomepirac, placebo and paracetamol/dextropropoxyphene combination compared in orthopaedic postoperative pain. Br. J. Anaesth. 54:1982;927-933.
9. Harvey I., Peters T.J., Toth B. Meta-analysis. Lancet. 341:1993;964.
10. Jadad, A.R., Meta-analysis of Randomised Clinical Trials in Pain Relief, D. Phil. thesis, University of Oxford, 1994.
11. McQuay H.J., Bullingham R.E.S., Moore R.A., Carroll D., Evans P.J.D., O'Sullivan G., Collin J., Lloyd J.W. Zomepirac, dihydrocodeine and placebo compared in postoperative pain after day-case surgery: the relationship between the effects of single and multiple doses. Br. J. Anaesth. 33:1985;412-419.
12. McQuay H.J., Carroll D., Frankland T., Harvey M., Moore A. Bromfenac, acetaminophen, and placebo in orthopedic postoperative pain. Clin. Pharmacol. Ther. 47:1990;760-766.
13. McQuay H.J., Carroll D., Guest P., Juniper R.P., Moore R.A. A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery. Anaesthesia. 47:1992;672-677.
14. McQuay H.J., Carroll D., Guest P.G., Robson S., Wiffen P.J., Juniper R.P. A multiple dose comparison of ibuprofen and dihydrocodeine after third molar surgery. Br. J. Oral Maxillofac. Surg. 31:1993;95-100.
15. McQuay H., Carroll D., Moore A. Variation in the placebo effect in randomised controlled trials of analgesics: All is as blind as it seems. Pain. 64:1996;331-335.
16. McQuay H.J., Carroll D., Poppleton P., Summerfield R.J., Moore R.A. Fluradoline and aspirin for orthopedic postoperative pain. Clin. Pharmacol. Ther. 41:1987;531-536.
17. McQuay H.J., Carroll D., Watts P.G., Juniper R.P., Moore R.A. Does adding small doses of codeine increase pain relief after third molar surgery. Clin. J. Pain. 2:1987;197-201.
18. McQuay H.J., Carroll D., Watts P.G., Juniper R.J., Moore R.A. Codeine 20 mg increases pain relief from ibuprofen 400 mg after third molar surgery. Pain. 37:1989;7-13.
19. McQuay H.J., Poppleton P., Carroll D., Summerfield R.J., Bullingham R.E.S., Moore R.A. Ketorolac and acetaminophen for orthopedic postoperative pain. Clin. Pharmacol. Ther. 39:1986;89-93.
20. Moertel C.G., Ahmann D.L., Taylor W.F., Schwartau N. Relief of pain by oral medications: a controlled evaluation of analgesic combinations. J. Am. Med. Assoc. 229:1974;55-59.
21. Porter E.J.B., Rolfe M., McQuay H.J., Moore R.A., Bullingham R.E.S. Single dose comparison of bicifadine, codeine and placebo in postoperative pain. Curr. Ther. Res. 30:1981;156-160.
22. Schulz K.F., Chalmers I., Hayes R.J., Altman D.G. Empirical evidence of bias. J. Am. Med. Assoc. 273:1995;408-412.
23. Stewart L.A., Parmar M.K.B. Meta-analysis of the literature or of individual patient data: is there a difference. Lancet. 341:1993;418-422.