메뉴 건너뛰기




Volumn 320, Issue 13, 2018, Pages 1360-1372

Diagnosis and Management of Rheumatoid Arthritis: A Review

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; BIOLOGICAL PRODUCT; GLUCOCORTICOID; METHOTREXATE;

EID: 85054381593     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2018.13103     Document Type: Review
Times cited : (1482)

References (108)
  • 1
    • 77952894832 scopus 로고    scopus 로고
    • Is the incidence of rheumatoid arthritis rising results from Olmsted County, Minnesota, 1955-2007
    • 20191579
    • Myasoedova E, Crowson CS, Kremers HM, Therneau TM, Gabriel SE. Is the incidence of rheumatoid arthritis rising? results from Olmsted County, Minnesota, 1955-2007. Arthritis Rheum. 2010; 62 (6): 1576-1582. doi: 10.1002/art.27425 20191579
    • (2010) Arthritis Rheum , vol.62 , Issue.6 , pp. 1576-1582
    • Myasoedova, E.1    Crowson, C.S.2    Kremers, H.M.3    Therneau, T.M.4    Gabriel, S.E.5
  • 2
    • 79953299484 scopus 로고    scopus 로고
    • Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction
    • 21321002
    • Aletaha D, Funovits J, Smolen JS. Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction. Ann Rheum Dis. 2011; 70 (5): 733-739. doi: 10.1136/ard.2010.138693 21321002
    • (2011) Ann Rheum Dis , vol.70 , Issue.5 , pp. 733-739
    • Aletaha, D.1    Funovits, J.2    Smolen, J.S.3
  • 3
    • 85019208873 scopus 로고    scopus 로고
    • Efficacy of biological disease-modifying antirheumatic drugs: A systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis
    • 28283512
    • Nam JL, Takase-Minegishi K, Ramiro S, Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2017; 76 (6): 1113-1136. doi: 10.1136/annrheumdis-2016-210713 28283512
    • (2017) Ann Rheum Dis , vol.76 , Issue.6 , pp. 1113-1136
    • Nam, J.L.1    Takase-Minegishi, K.2    Ramiro, S.3
  • 4
    • 85019190499 scopus 로고    scopus 로고
    • Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: A systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis
    • 28356243
    • Chatzidionysiou K, Emamikia S, Nam J, Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2017; 76 (6): 1102-1107. doi: 10.1136/annrheumdis-2016-210711 28356243
    • (2017) Ann Rheum Dis , vol.76 , Issue.6 , pp. 1102-1107
    • Chatzidionysiou, K.1    Emamikia, S.2    Nam, J.3
  • 5
    • 85019245378 scopus 로고    scopus 로고
    • Safety of synthetic and biological DMARDs: A systematic literature review informing the 2016 update of the EULAR recommendations for management of rheumatoid arthritis
    • 28298374
    • Ramiro S, Sepriano A, Chatzidionysiou K, Safety of synthetic and biological DMARDs: a systematic literature review informing the 2016 update of the EULAR recommendations for management of rheumatoid arthritis. Ann Rheum Dis. 2017; 76 (6): 1101-1136. doi: 10.1136/annrheumdis-2016-210708 28298374
    • (2017) Ann Rheum Dis , vol.76 , Issue.6 , pp. 1101-1136
    • Ramiro, S.1    Sepriano, A.2    Chatzidionysiou, K.3
  • 6
    • 84959229698 scopus 로고    scopus 로고
    • The cybernetics of TNF: Old views and newer ones
    • 26474540
    • Wallach D. The cybernetics of TNF: old views and newer ones. Semin Cell Dev Biol. 2016; 50: 105-114. doi: 10.1016/j.semcdb.2015.10.014 26474540
    • (2016) Semin Cell Dev Biol , vol.50 , pp. 105-114
    • Wallach, D.1
  • 7
    • 84857737880 scopus 로고    scopus 로고
    • Inflammatory bone loss: Pathogenesis and therapeutic intervention
    • 22378270
    • Redlich K, Smolen JS. Inflammatory bone loss: pathogenesis and therapeutic intervention. Nat Rev Drug Discov. 2012; 11 (3): 234-250. doi: 10.1038/nrd3669 22378270
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.3 , pp. 234-250
    • Redlich, K.1    Smolen, J.S.2
  • 8
    • 82455198746 scopus 로고    scopus 로고
    • Joint damage in rheumatoid arthritis progresses in remission according to the Disease Activity Score in 28 joints and is driven by residual swollen joints
    • 21953215
    • Aletaha D, Smolen JS. Joint damage in rheumatoid arthritis progresses in remission according to the Disease Activity Score in 28 joints and is driven by residual swollen joints. Arthritis Rheum. 2011; 63 (12): 3702-3711. doi: 10.1002/art.30634 21953215
    • (2011) Arthritis Rheum , vol.63 , Issue.12 , pp. 3702-3711
    • Aletaha, D.1    Smolen, J.S.2
  • 9
    • 85019692719 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis susceptibility, severity, and treatment response
    • 28555384
    • Viatte S, Barton A. Genetics of rheumatoid arthritis susceptibility, severity, and treatment response. Semin Immunopathol. 2017; 39 (4): 395-408. doi: 10.1007/s00281-017-0630-4 28555384
    • (2017) Semin Immunopathol , vol.39 , Issue.4 , pp. 395-408
    • Viatte, S.1    Barton, A.2
  • 10
    • 84884691464 scopus 로고    scopus 로고
    • Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking
    • 24068971
    • Scott IC, Seegobin SD, Steer S, Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking. PLoS Genet. 2013; 9 (9): e1003808. doi: 10.1371/journal.pgen.1003808 24068971
    • (2013) PLoS Genet , vol.9 , Issue.9 , pp. e1003808
    • Scott, I.C.1    Seegobin, S.D.2    Steer, S.3
  • 11
    • 84867054370 scopus 로고    scopus 로고
    • Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis
    • 22576262
    • Scher JU, Ubeda C, Equinda M, Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis. Arthritis Rheum. 2012; 64 (10): 3083-3094. doi: 10.1002/art.34539 22576262
    • (2012) Arthritis Rheum , vol.64 , Issue.10 , pp. 3083-3094
    • Scher, J.U.1    Ubeda, C.2    Equinda, M.3
  • 12
    • 84919932773 scopus 로고    scopus 로고
    • Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease
    • 25319745
    • Scher JU, Ubeda C, Artacho A, Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease. Arthritis Rheumatol. 2015; 67 (1): 128-139. doi: 10.1002/art.38892 25319745
    • (2015) Arthritis Rheumatol , vol.67 , Issue.1 , pp. 128-139
    • Scher, J.U.1    Ubeda, C.2    Artacho, A.3
  • 13
    • 84992197087 scopus 로고    scopus 로고
    • Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor
    • 27621417
    • Tan EM, Smolen JS. Historical observations contributing insights on etiopathogenesis of rheumatoid arthritis and role of rheumatoid factor. J Exp Med. 2016; 213 (10): 1937-1950. doi: 10.1084/jem.20160792 27621417
    • (2016) J Exp Med , vol.213 , Issue.10 , pp. 1937-1950
    • Tan, E.M.1    Smolen, J.S.2
  • 14
    • 0029877828 scopus 로고    scopus 로고
    • Cigarette smoking increases the risk of rheumatoid arthritis: Results from a nationwide study of disease-discordant twins
    • 8639169
    • Silman AJ, Newman J, MacGregor AJ. Cigarette smoking increases the risk of rheumatoid arthritis: results from a nationwide study of disease-discordant twins. Arthritis Rheum. 1996; 39 (5): 732-735. doi: 10.1002/art.1780390504 8639169
    • (1996) Arthritis Rheum , vol.39 , Issue.5 , pp. 732-735
    • Silman, A.J.1    Newman, J.2    Macgregor, A.J.3
  • 15
    • 16344369383 scopus 로고    scopus 로고
    • Silica exposure is associated with increased risk of developing rheumatoid arthritis: Results from the Swedish EIRA study
    • 15319232
    • Stolt P, Källberg H, Lundberg I, Sjögren B, Klareskog L, Alfredsson L; EIRA Study Group. Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA study. Ann Rheum Dis. 2005; 64 (4): 582-586. doi: 10.1136/ard.2004.022053 15319232
    • (2005) Ann Rheum Dis , vol.64 , Issue.4 , pp. 582-586
    • Stolt, P.1    Källberg, H.2    Lundberg, I.3    Sjögren, B.4    Klareskog, L.5    Alfredsson, L.6
  • 16
    • 0023500817 scopus 로고
    • The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • 2446635
    • Gregersen PK, Silver J, Winchester RJ. The shared epitope hypothesis: an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum. 1987; 30 (11): 1205-1213. doi: 10.1002/art.1780301102 2446635
    • (1987) Arthritis Rheum , vol.30 , Issue.11 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 17
    • 75749099775 scopus 로고    scopus 로고
    • Recent advances in the genetics of rheumatoid arthritis
    • 20075733
    • Raychaudhuri S. Recent advances in the genetics of rheumatoid arthritis. Curr Opin Rheumatol. 2010; 22 (2): 109-118. doi: 10.1097/BOR.0b013e328336474d 20075733
    • (2010) Curr Opin Rheumatol , vol.22 , Issue.2 , pp. 109-118
    • Raychaudhuri, S.1
  • 18
    • 84887323708 scopus 로고    scopus 로고
    • Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
    • 24192039
    • Scher JU, Sczesnak A, Longman RS, Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife. 2013; 2: e01202. doi: 10.7554/eLife.01202 24192039
    • (2013) Elife , vol.2 , pp. e01202
    • Scher, J.U.1    Sczesnak, A.2    Longman, R.S.3
  • 19
    • 77955733490 scopus 로고    scopus 로고
    • Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis
    • 20506214
    • Wegner N, Wait R, Sroka A, Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum. 2010; 62 (9): 2662-2672. doi: 10.1002/art.27552 20506214
    • (2010) Arthritis Rheum , vol.62 , Issue.9 , pp. 2662-2672
    • Wegner, N.1    Wait, R.2    Sroka, A.3
  • 20
    • 85043285818 scopus 로고    scopus 로고
    • Translocation of a gut pathobiont drives autoimmunity in mice and humans
    • 29590047
    • Manfredo Vieira S, Hiltensperger M, Kumar V, Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science. 2018; 359 (6380): 1156-1161. doi: 10.1126/science.aar7201 29590047
    • (2018) Science , vol.359 , Issue.6380 , pp. 1156-1161
    • Manfredo Vieira, S.1    Hiltensperger, M.2    Kumar, V.3
  • 21
    • 85026642886 scopus 로고    scopus 로고
    • Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints
    • 28650341
    • Pianta A, Arvikar SL, Strle K, Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints. J Clin Invest. 2017; 127 (8): 2946-2956. doi: 10.1172/JCI93450 28650341
    • (2017) J Clin Invest , vol.127 , Issue.8 , pp. 2946-2956
    • Pianta, A.1    Arvikar, S.L.2    Strle, K.3
  • 22
    • 84934961354 scopus 로고    scopus 로고
    • Potential role of bacterial infection in autoimmune diseases: A new aspect of molecular mimicry
    • 24605075
    • Alam J, Kim YC, Choi Y. Potential role of bacterial infection in autoimmune diseases: a new aspect of molecular mimicry. Immune Netw. 2014; 14 (1): 7-13. doi: 10.4110/in.2014.14.1.7 24605075
    • (2014) Immune Netw , vol.14 , Issue.1 , pp. 7-13
    • Alam, J.1    Kim, Y.C.2    Choi, Y.3
  • 23
    • 85045436990 scopus 로고    scopus 로고
    • Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity
    • 29662164
    • Harley JB, Chen X, Pujato M, Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. Nat Genet. 2018; 50 (5): 699-707. doi: 10.1038/s41588-018-0102-3 29662164
    • (2018) Nat Genet , vol.50 , Issue.5 , pp. 699-707
    • Harley, J.B.1    Chen, X.2    Pujato, M.3
  • 24
    • 85015788725 scopus 로고    scopus 로고
    • Epigenetics in the pathogenesis of RA
    • 28324153
    • Ospelt C, Gay S, Klein K. Epigenetics in the pathogenesis of RA. Semin Immunopathol. 2017; 39 (4): 409-419. doi: 10.1007/s00281-017-0621-5 28324153
    • (2017) Semin Immunopathol , vol.39 , Issue.4 , pp. 409-419
    • Ospelt, C.1    Gay, S.2    Klein, K.3
  • 25
    • 84940213137 scopus 로고    scopus 로고
    • Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials
    • 26307354
    • Aletaha D, Alasti F, Smolen JS. Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials. Arthritis Res Ther. 2015; 17: 229. doi: 10.1186/s13075-015-0736-9 26307354
    • (2015) Arthritis Res Ther , vol.17 , pp. 229
    • Aletaha, D.1    Alasti, F.2    Smolen, J.S.3
  • 26
    • 84898612198 scopus 로고    scopus 로고
    • Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis
    • 24757134
    • Sokolove J, Johnson DS, Lahey LJ, Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2014; 66 (4): 813-821. doi: 10.1002/art.38307 24757134
    • (2014) Arthritis Rheumatol , vol.66 , Issue.4 , pp. 813-821
    • Sokolove, J.1    Johnson, D.S.2    Lahey, L.J.3
  • 27
    • 1042290337 scopus 로고    scopus 로고
    • Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors
    • 14872479
    • Nielen MM, van Schaardenburg D, Reesink HW, Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. Arthritis Rheum. 2004; 50 (2): 380-386. doi: 10.1002/art.20018 14872479
    • (2004) Arthritis Rheum , vol.50 , Issue.2 , pp. 380-386
    • Nielen, M.M.1    Van Schaardenburg, D.2    Reesink, H.W.3
  • 28
    • 84896299794 scopus 로고    scopus 로고
    • Features of the synovium of individuals at risk of developing rheumatoid arthritis: Implications for understanding preclinical rheumatoid arthritis
    • 24574210
    • de Hair MJ, van de Sande MG, Ramwadhdoebe TH, Features of the synovium of individuals at risk of developing rheumatoid arthritis: implications for understanding preclinical rheumatoid arthritis. Arthritis Rheumatol. 2014; 66 (3): 513-522. doi: 10.1002/art.38273 24574210
    • (2014) Arthritis Rheumatol , vol.66 , Issue.3 , pp. 513-522
    • De Hair, M.J.1    Van De Sande, M.G.2    Ramwadhdoebe, T.H.3
  • 29
    • 85038236789 scopus 로고    scopus 로고
    • Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis
    • 28877868
    • Crowson CS, Rollefstad S, Ikdahl E,; A Trans-Atlantic Cardiovascular Consortium for Rheumatoid Arthritis (ATACC-RA). Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis. Ann Rheum Dis. 2018; 77 (1): 48-54. doi: 10.1136/annrheumdis-2017-211735 28877868
    • (2018) Ann Rheum Dis , vol.77 , Issue.1 , pp. 48-54
    • Crowson, C.S.1    Rollefstad, S.2    Ikdahl, E.3
  • 30
    • 85010402970 scopus 로고    scopus 로고
    • Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis
    • 28073800
    • Low AS, Symmons DP, Lunt M,; British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (BSRBR-RA) and the BSRBR Control Centre Consortium. Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis. Ann Rheum Dis. 2017; 76 (4): 654-660. doi: 10.1136/annrheumdis-2016-209784 28073800
    • (2017) Ann Rheum Dis , vol.76 , Issue.4 , pp. 654-660
    • Low, A.S.1    Symmons, D.P.2    Lunt, M.3
  • 31
    • 77952933999 scopus 로고    scopus 로고
    • Incidence and mortality of interstitial lung disease in rheumatoid arthritis: A population-based study
    • 20155830
    • Bongartz T, Nannini C, Medina-Velasquez YF, Incidence and mortality of interstitial lung disease in rheumatoid arthritis: a population-based study. Arthritis Rheum. 2010; 62 (6): 1583-1591. doi: 10.1002/art.27405 20155830
    • (2010) Arthritis Rheum , vol.62 , Issue.6 , pp. 1583-1591
    • Bongartz, T.1    Nannini, C.2    Medina-Velasquez, Y.F.3
  • 32
    • 0032770474 scopus 로고    scopus 로고
    • Work disability in rheumatoid arthritis 10 years after the diagnosis
    • 10451062
    • Sokka T, Kautiainen H, Möttönen T, Hannonen P. Work disability in rheumatoid arthritis 10 years after the diagnosis. J Rheumatol. 1999; 26 (8): 1681-1685. 10451062
    • (1999) J Rheumatol , vol.26 , Issue.8 , pp. 1681-1685
    • Sokka, T.1    Kautiainen, H.2    Möttönen, T.3    Hannonen, P.4
  • 33
    • 0029868302 scopus 로고    scopus 로고
    • The natural history of rheumatoid arthritis
    • 8833046
    • Wolfe F. The natural history of rheumatoid arthritis. J Rheumatol Suppl. 1996; 44: 13-22. 8833046
    • (1996) J Rheumatol Suppl , vol.44 , pp. 13-22
    • Wolfe, F.1
  • 34
    • 84927578420 scopus 로고    scopus 로고
    • The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: A systematic review and meta-analysis
    • 24973898
    • Matcham F, Scott IC, Rayner L, The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: a systematic review and meta-analysis. Semin Arthritis Rheum. 2014; 44 (2): 123-130. doi: 10.1016/j.semarthrit.2014.05.001 24973898
    • (2014) Semin Arthritis Rheum , vol.44 , Issue.2 , pp. 123-130
    • Matcham, F.1    Scott, I.C.2    Rayner, L.3
  • 35
    • 78751695495 scopus 로고    scopus 로고
    • Comorbidity affects all domains of physical function and quality of life in patients with rheumatoid arthritis
    • 21036875
    • Radner H, Smolen JS, Aletaha D. Comorbidity affects all domains of physical function and quality of life in patients with rheumatoid arthritis. Rheumatology (Oxford). 2011; 50 (2): 381-388. doi: 10.1093/rheumatology/keq334 21036875
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.2 , pp. 381-388
    • Radner, H.1    Smolen, J.S.2    Aletaha, D.3
  • 36
    • 38749129727 scopus 로고    scopus 로고
    • Treatment-related improvement in physical function varies with duration of rheumatoid arthritis: A pooled analysis of clinical trial results
    • 17644550
    • Aletaha D, Strand V, Smolen JS, Ward MM. Treatment-related improvement in physical function varies with duration of rheumatoid arthritis: a pooled analysis of clinical trial results. Ann Rheum Dis. 2008; 67 (2): 238-243. doi: 10.1136/ard.2007.071415 17644550
    • (2008) Ann Rheum Dis , vol.67 , Issue.2 , pp. 238-243
    • Aletaha, D.1    Strand, V.2    Smolen, J.S.3    Ward, M.M.4
  • 37
    • 77956036473 scopus 로고    scopus 로고
    • 2010 rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative
    • 20699241
    • Aletaha D, Neogi T, Silman A, 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2010; 69: 1580-1588. doi: 10.1136/ard.2010.138461 20699241
    • (2010) Ann Rheum Dis , vol.69 , pp. 1580-1588
    • Aletaha, D.1    Neogi, T.2    Silman, A.3
  • 38
    • 84889636584 scopus 로고    scopus 로고
    • Performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: A systematic literature review
    • 23592710
    • Radner H, Neogi T, Smolen JS, Aletaha D. Performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: a systematic literature review. Ann Rheum Dis. 2014; 73 (1): 114-123. doi: 10.1136/annrheumdis-2013-203284 23592710
    • (2014) Ann Rheum Dis , vol.73 , Issue.1 , pp. 114-123
    • Radner, H.1    Neogi, T.2    Smolen, J.S.3    Aletaha, D.4
  • 39
    • 84932626672 scopus 로고    scopus 로고
    • Distinctions between diagnostic and classification criteria?
    • 25776731
    • Aggarwal R, Ringold S, Khanna D, Distinctions between diagnostic and classification criteria? Arthritis Care Res (Hoboken). 2015; 67 (7): 891-897. doi: 10.1002/acr.22583 25776731
    • (2015) Arthritis Care Res (Hoboken) , vol.67 , Issue.7 , pp. 891-897
    • Aggarwal, R.1    Ringold, S.2    Khanna, D.3
  • 40
    • 27744514865 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial
    • 16258899
    • Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum. 2005; 52 (11): 3381-3390. doi: 10.1002/art.21405 16258899
    • (2005) Arthritis Rheum , vol.52 , Issue.11 , pp. 3381-3390
    • Goekoop-Ruiterman, Y.P.1    De Vries-Bouwstra, J.K.2    Allaart, C.F.3
  • 41
    • 0036210080 scopus 로고    scopus 로고
    • Early referral recommendation for newly diagnosed rheumatoid arthritis: Evidence based development of a clinical guide
    • 11874828
    • Emery P, Breedveld FC, Dougados M, Kalden JR, Schiff MH, Smolen JS. Early referral recommendation for newly diagnosed rheumatoid arthritis: evidence based development of a clinical guide. Ann Rheum Dis. 2002; 61 (4): 290-297. doi: 10.1136/ard.61.4.290 11874828
    • (2002) Ann Rheum Dis , vol.61 , Issue.4 , pp. 290-297
    • Emery, P.1    Breedveld, F.C.2    Dougados, M.3    Kalden, J.R.4    Schiff, M.H.5    Smolen, J.S.6
  • 42
    • 23944478301 scopus 로고    scopus 로고
    • Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: Validation of a clinical activity score
    • 15987481
    • Aletaha D, Nell VPK, Stamm T, Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score. Arthritis Res Ther. 2005; 7 (4): R796-R806. doi: 10.1186/ar1740 15987481
    • (2005) Arthritis Res Ther , vol.7 , Issue.4 , pp. R796-R806
    • Aletaha, D.1    Nell, V.P.K.2    Stamm, T.3
  • 43
    • 0026630114 scopus 로고
    • Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: A prospective follow-up study of 147 patients
    • 1386548
    • van der Heijde DM, van Riel PL, van Leeuwen MA, van 't Hof MA, van Rijswijk MH, van de Putte LB. Prognostic factors for radiographic damage and physical disability in early rheumatoid arthritis: a prospective follow-up study of 147 patients. Br J Rheumatol. 1992; 31 (8): 519-525. doi: 10.1093/rheumatology/31.8.519 1386548
    • (1992) Br J Rheumatol , vol.31 , Issue.8 , pp. 519-525
    • Van Der Heijde, D.M.1    Van Riel, P.L.2    Van Leeuwen, M.A.3    Van 'T Hof, M.A.4    Van Rijswijk, M.H.5    Van De Putte, L.B.6
  • 44
    • 33644895018 scopus 로고    scopus 로고
    • Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: Results from the ASPIRE trial
    • 16508926
    • Smolen JS, Van Der Heijde DM, St Clair EW,; Active-Controlled Study of Patients Receiving Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset (ASPIRE) Study Group. Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum. 2006; 54 (3): 702-710. doi: 10.1002/art.21678 16508926
    • (2006) Arthritis Rheum , vol.54 , Issue.3 , pp. 702-710
    • Smolen, J.S.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 45
    • 84930607509 scopus 로고    scopus 로고
    • Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force
    • 25969430
    • Smolen JS, Breedveld FC, Burmester GR, Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis. 2016; 75 (1): 3-15. doi: 10.1136/annrheumdis-2015-207524 25969430
    • (2016) Ann Rheum Dis , vol.75 , Issue.1 , pp. 3-15
    • Smolen, J.S.1    Breedveld, F.C.2    Burmester, G.R.3
  • 46
    • 84982792250 scopus 로고    scopus 로고
    • Optimisation of a treat-to-target approach in rheumatoid arthritis: Strategies for the 3-month time point
    • 26420577
    • Aletaha D, Alasti F, Smolen JS. Optimisation of a treat-to-target approach in rheumatoid arthritis: strategies for the 3-month time point. Ann Rheum Dis. 2016; 75 (8): 1479-1485. doi: 10.1136/annrheumdis-2015-208324 26420577
    • (2016) Ann Rheum Dis , vol.75 , Issue.8 , pp. 1479-1485
    • Aletaha, D.1    Alasti, F.2    Smolen, J.S.3
  • 47
    • 79951506884 scopus 로고    scopus 로고
    • American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials
    • 21292833
    • Felson DT, Smolen JS, Wells G, American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials. Ann Rheum Dis. 2011; 70 (3): 404-413. doi: 10.1136/ard.2011.149765 21292833
    • (2011) Ann Rheum Dis , vol.70 , Issue.3 , pp. 404-413
    • Felson, D.T.1    Smolen, J.S.2    Wells, G.3
  • 48
    • 84969939951 scopus 로고    scopus 로고
    • Targeting ultrasound remission in early rheumatoid arthritis: The results of the TaSER study, a randomised clinical trial
    • 27026689
    • Dale J, Stirling A, Zhang R, Targeting ultrasound remission in early rheumatoid arthritis: the results of the TaSER study, a randomised clinical trial. Ann Rheum Dis. 2016; 75 (6): 1043-1050. doi: 10.1136/annrheumdis-2015-208941 27026689
    • (2016) Ann Rheum Dis , vol.75 , Issue.6 , pp. 1043-1050
    • Dale, J.1    Stirling, A.2    Zhang, R.3
  • 49
    • 84973309330 scopus 로고    scopus 로고
    • Certolizumab pegol in combination with dose-optimised methotrexate in DMARD-naïve patients with early, active rheumatoid arthritis with poor prognostic factors: 1-year results from C-EARLY, a randomised, double-blind, placebo-controlled phase III study
    • 27165179
    • Emery P, Bingham CO III, Burmester GR, Certolizumab pegol in combination with dose-optimised methotrexate in DMARD-naïve patients with early, active rheumatoid arthritis with poor prognostic factors: 1-year results from C-EARLY, a randomised, double-blind, placebo-controlled phase III study. Ann Rheum Dis. 2017; 76 (1): 96-104. doi: 10.1136/annrheumdis-2015-209057 27165179
    • (2017) Ann Rheum Dis , vol.76 , Issue.1 , pp. 96-104
    • Emery, P.1    Bingham, C.O.2    Burmester, G.R.3
  • 50
    • 31044442965 scopus 로고    scopus 로고
    • The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
    • 16385520
    • Breedveld FC, Weisman MH, Kavanaugh AF, The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum. 2006; 54 (1): 26-37. doi: 10.1002/art.21519 16385520
    • (2006) Arthritis Rheum , vol.54 , Issue.1 , pp. 26-37
    • Breedveld, F.C.1    Weisman, M.H.2    Kavanaugh, A.F.3
  • 51
    • 0033053835 scopus 로고    scopus 로고
    • Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: A double-blind, randomised, multicentre trial
    • 9929017
    • Smolen JS, Kalden JR, Scott DL,; European Leflunomide Study Group. Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial. Lancet. 1999; 353 (9149): 259-266. doi: 10.1016/S0140-6736(98)09403-3 9929017
    • (1999) Lancet , vol.353 , Issue.9149 , pp. 259-266
    • Smolen, J.S.1    Kalden, J.R.2    Scott, D.L.3
  • 52
    • 84864703156 scopus 로고    scopus 로고
    • Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
    • 22873531
    • van Vollenhoven RF, Fleischmann R, Cohen S,; ORAL Standard Investigators. Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Engl J Med. 2012; 367 (6): 508-519. doi: 10.1056/NEJMoa1112072 22873531
    • (2012) N Engl J Med , vol.367 , Issue.6 , pp. 508-519
    • Van Vollenhoven, R.F.1    Fleischmann, R.2    Cohen, S.3
  • 53
    • 84873707288 scopus 로고    scopus 로고
    • Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: A randomised phase 3 trial
    • 23294500
    • Burmester GR, Blanco R, Charles-Schoeman C,; ORAL Step Investigators. Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial. Lancet. 2013; 381 (9865): 451-460. doi: 10.1016/S0140-6736(12)61424-X 23294500
    • (2013) Lancet , vol.381 , Issue.9865 , pp. 451-460
    • Burmester, G.R.1    Blanco, R.2    Charles-Schoeman, C.3
  • 54
    • 84991491965 scopus 로고    scopus 로고
    • Baricitinib in patients with inadequate response or intolerance to conventional synthetic DMARDs: Results from the RA-BUILD study
    • 27689735
    • Dougados M, van der Heijde D, Chen YC, Baricitinib in patients with inadequate response or intolerance to conventional synthetic DMARDs: results from the RA-BUILD study. Ann Rheum Dis. 2017; 76 (1): 88-95. doi: 10.1136/annrheumdis-2016-210094 27689735
    • (2017) Ann Rheum Dis , vol.76 , Issue.1 , pp. 88-95
    • Dougados, M.1    Van Der Heijde, D.2    Chen, Y.C.3
  • 55
    • 84962375370 scopus 로고    scopus 로고
    • Baricitinib in patients with refractory rheumatoid arthritis
    • 27028914
    • Genovese MC, Kremer J, Zamani O, Baricitinib in patients with refractory rheumatoid arthritis. N Engl J Med. 2016; 374 (13): 1243-1252. doi: 10.1056/NEJMoa1507247 27028914
    • (2016) N Engl J Med , vol.374 , Issue.13 , pp. 1243-1252
    • Genovese, M.C.1    Kremer, J.2    Zamani, O.3
  • 56
    • 67650379733 scopus 로고    scopus 로고
    • Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): A multicentre, randomised, double-blind, placebo-controlled, phase III trial
    • 19560810
    • Smolen JS, Kay J, Doyle MK,; GO-AFTER Study Investigators. Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial. Lancet. 2009; 374 (9685): 210-221. doi: 10.1016/S0140-6736(09)60506-7 19560810
    • (2009) Lancet , vol.374 , Issue.9685 , pp. 210-221
    • Smolen, J.S.1    Kay, J.2    Doyle, M.K.3
  • 57
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
    • 18358926
    • Smolen JS, Beaulieu A, Rubbert-Roth A,; OPTION Investigators. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet. 2008; 371 (9617): 987-997. doi: 10.1016/S0140-6736(08)60453-5 18358926
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3
  • 58
    • 52149099504 scopus 로고    scopus 로고
    • IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomised placebo-controlled trial
    • 18625622
    • Emery P, Keystone E, Tony HP, IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann Rheum Dis. 2008; 67 (11): 1516-1523. doi: 10.1136/ard.2008.092932 18625622
    • (2008) Ann Rheum Dis , vol.67 , Issue.11 , pp. 1516-1523
    • Emery, P.1    Keystone, E.2    Tony, H.P.3
  • 59
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
    • 16649186
    • Emery P, Fleischmann R, Filipowicz-Sosnowska A,; DANCER Study Group. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum. 2006; 54 (5): 1390-1400. doi: 10.1002/art.21778 16649186
    • (2006) Arthritis Rheum , vol.54 , Issue.5 , pp. 1390-1400
    • Emery, P.1    Fleischmann, R.2    Filipowicz-Sosnowska, A.3
  • 60
    • 33746961890 scopus 로고    scopus 로고
    • Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
    • 16947627
    • Cohen SB, Emery P, Greenwald MW,; REFLEX Trial Group. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum. 2006; 54 (9): 2793-2806. doi: 10.1002/art.22025 16947627
    • (2006) Arthritis Rheum , vol.54 , Issue.9 , pp. 2793-2806
    • Cohen, S.B.1    Emery, P.2    Greenwald, M.W.3
  • 61
    • 33745291091 scopus 로고    scopus 로고
    • Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
    • 16785475
    • Kremer JM, Genant HK, Moreland LW, Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med. 2006; 144 (12): 865-876. doi: 10.7326/0003-4819-144-12-200606200-00003 16785475
    • (2006) Ann Intern Med , vol.144 , Issue.12 , pp. 865-876
    • Kremer, J.M.1    Genant, H.K.2    Moreland, L.W.3
  • 62
    • 24944498854 scopus 로고    scopus 로고
    • Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
    • 16162882
    • Genovese MC, Becker JC, Schiff M, Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005; 353 (11): 1114-1123. doi: 10.1056/NEJMoa050524 16162882
    • (2005) N Engl J Med , vol.353 , Issue.11 , pp. 1114-1123
    • Genovese, M.C.1    Becker, J.C.2    Schiff, M.3
  • 63
    • 85041496935 scopus 로고    scopus 로고
    • Consensus-based recommendations for the use of biosimilars to treat rheumatological diseases
    • 28866648
    • Kay J, Schoels MM, Dörner T,; Task Force on the Use of Biosimilars to Treat Rheumatological Diseases. Consensus-based recommendations for the use of biosimilars to treat rheumatological diseases. Ann Rheum Dis. 2018; 77 (2): 165-174. doi: 10.1136/annrheumdis-2017-211937 28866648
    • (2018) Ann Rheum Dis , vol.77 , Issue.2 , pp. 165-174
    • Kay, J.1    Schoels, M.M.2    Dörner, T.3
  • 64
    • 84889683898 scopus 로고    scopus 로고
    • Proposal for a new nomenclature of disease-modifying antirheumatic drugs
    • 24072562
    • Smolen JS, van der Heijde D, Machold KP, Aletaha D, Landewé R. Proposal for a new nomenclature of disease-modifying antirheumatic drugs. Ann Rheum Dis. 2014; 73 (1): 3-5. doi: 10.1136/annrheumdis-2013-204317 24072562
    • (2014) Ann Rheum Dis , vol.73 , Issue.1 , pp. 3-5
    • Smolen, J.S.1    Van Der Heijde, D.2    Machold, K.P.3    Aletaha, D.4    Landewé, R.5
  • 65
    • 0021080093 scopus 로고
    • Methotrexate therapy in rheumatoid arthritis: 15 years experience
    • 6660241
    • Hoffmeister RT. Methotrexate therapy in rheumatoid arthritis: 15 years experience. Am J Med. 1983; 75 (6A): 69-73. doi: 10.1016/0002-9343(83)90477-1 6660241
    • (1983) Am J Med , vol.75 , Issue.6 A , pp. 69-73
    • Hoffmeister, R.T.1
  • 66
    • 0034944211 scopus 로고    scopus 로고
    • Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: A forty-eight week, multicenter, randomized, double-blind, placebo-controlled study
    • 11465701
    • van Ede AE, Laan RF, Rood MJ, Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum. 2001; 44 (7): 1515-1524. doi: 10.1002/1529-0131(200107)44:7<1515::AID-ART273>3.0.CO;2-7 11465701
    • (2001) Arthritis Rheum , vol.44 , Issue.7 , pp. 1515-1524
    • Van Ede, A.E.1    Laan, R.F.2    Rood, M.J.3
  • 67
    • 84889677643 scopus 로고    scopus 로고
    • Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: A double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study)
    • 23912798
    • Nam JL, Villeneuve E, Hensor EM, Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study). Ann Rheum Dis. 2014; 73 (1): 75-85. doi: 10.1136/annrheumdis-2013-203440 23912798
    • (2014) Ann Rheum Dis , vol.73 , Issue.1 , pp. 75-85
    • Nam, J.L.1    Villeneuve, E.2    Hensor, E.M.3
  • 68
    • 0025058790 scopus 로고
    • Sulphasalazine versus hydroxychloroquine in rheumatoid arthritis: 3-year follow-up
    • 1968547
    • van der Heijde DM, van Riel PL, Nuver-Zwart IH, van de Putte LB. Sulphasalazine versus hydroxychloroquine in rheumatoid arthritis: 3-year follow-up. Lancet. 1990; 335 (8688): 539. doi: 10.1016/0140-6736(90)90771-V 1968547
    • (1990) Lancet , vol.335 , Issue.8688 , pp. 539
    • Van Der Heijde, D.M.1    Van Riel, P.L.2    Nuver-Zwart, I.H.3    Van De Putte, L.B.4
  • 69
    • 85019702082 scopus 로고    scopus 로고
    • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
    • 28264816
    • Smolen JS, Landewé R, Bijlsma J, EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update. Ann Rheum Dis. 2017; 76 (6): 960-977. doi: 10.1136/annrheumdis-2016-210715 28264816
    • (2017) Ann Rheum Dis , vol.76 , Issue.6 , pp. 960-977
    • Smolen, J.S.1    Landewé, R.2    Bijlsma, J.3
  • 70
    • 84956767541 scopus 로고    scopus 로고
    • 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis
    • 26545825
    • Singh JA, Saag KG, Bridges SL Jr,; American College of Rheumatology. 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Care Res (Hoboken). 2016; 68 (1): 1-25. doi: 10.1002/acr.22783 26545825
    • (2016) Arthritis Care Res (Hoboken) , vol.68 , Issue.1 , pp. 1-25
    • Singh, J.A.1    Saag, K.G.2    Bridges, S.L.3
  • 71
    • 70349785532 scopus 로고    scopus 로고
    • A pilot risk model for the prediction of rapid radiographic progression in rheumatoid arthritis
    • 19589891
    • Vastesaeger N, Xu S, Aletaha D, St Clair EW, Smolen JS. A pilot risk model for the prediction of rapid radiographic progression in rheumatoid arthritis. Rheumatology (Oxford). 2009; 48 (9): 1114-1121. doi: 10.1093/rheumatology/kep155 19589891
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.9 , pp. 1114-1121
    • Vastesaeger, N.1    Xu, S.2    Aletaha, D.3    St Clair, E.W.4    Smolen, J.S.5
  • 72
    • 79955156664 scopus 로고    scopus 로고
    • Outcome in rheumatoid arthritis patients with continued conventional therapy for moderate disease activity - The early RA network (ERAN)
    • 21169343
    • Kiely P, Walsh D, Williams R, Young A; Early Rheumatoid Arthritis Network. Outcome in rheumatoid arthritis patients with continued conventional therapy for moderate disease activity-the early RA network (ERAN). Rheumatology (Oxford). 2011; 50 (5): 926-931. doi: 10.1093/rheumatology/keq406 21169343
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.5 , pp. 926-931
    • Kiely, P.1    Walsh, D.2    Williams, R.3    Young, A.4
  • 73
    • 85003681006 scopus 로고    scopus 로고
    • Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study
    • 10061 27863807
    • Smolen JS, Burmester GR, Combe B, Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study. Lancet. 2016; 388 (10061): 2763-2774. doi: 10.1016/S0140-6736(16)31651-8 27863807
    • (2016) Lancet , vol.388 , pp. 2763-2774
    • Smolen, J.S.1    Burmester, G.R.2    Combe, B.3
  • 74
    • 84946887746 scopus 로고    scopus 로고
    • Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial
    • 26511996
    • Burmester GR, Rigby WF, van Vollenhoven RF, Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial. Ann Rheum Dis. 2016; 75 (6): 1081-1091. doi: 10.1136/annrheumdis-2015-207628 26511996
    • (2016) Ann Rheum Dis , vol.75 , Issue.6 , pp. 1081-1091
    • Burmester, G.R.1    Rigby, W.F.2    Van Vollenhoven, R.F.3
  • 75
    • 84918571233 scopus 로고    scopus 로고
    • Evaluating drug-free remission with abatacept in early rheumatoid arthritis: Results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period
    • 25367713
    • Emery P, Burmester GR, Bykerk VP, Evaluating drug-free remission with abatacept in early rheumatoid arthritis: results from the phase 3b, multicentre, randomised, active-controlled AVERT study of 24 months, with a 12-month, double-blind treatment period. Ann Rheum Dis. 2015; 74 (1): 19-26. doi: 10.1136/annrheumdis-2014-206106 25367713
    • (2015) Ann Rheum Dis , vol.74 , Issue.1 , pp. 19-26
    • Emery, P.1    Burmester, G.R.2    Bykerk, V.P.3
  • 76
    • 84956630876 scopus 로고    scopus 로고
    • Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study)
    • 26733110
    • Kaneko Y, Atsumi T, Tanaka Y, Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study). Ann Rheum Dis. 2016; 75 (11): 1917-1923. doi: 10.1136/annrheumdis-2015-208426 26733110
    • (2016) Ann Rheum Dis , vol.75 , Issue.11 , pp. 1917-1923
    • Kaneko, Y.1    Atsumi, T.2    Tanaka, Y.3
  • 77
    • 85020770079 scopus 로고    scopus 로고
    • Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): A phase 3b/4, double-blind, head-to-head, randomised controlled trial
    • 10093 28629665
    • Fleischmann R, Mysler E, Hall S,; ORAL Strategy Investigators. Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4, double-blind, head-to-head, randomised controlled trial. Lancet. 2017; 390 (10093): 457-468. doi: 10.1016/S0140-6736(17)31618-5 28629665
    • (2017) Lancet , vol.390 , pp. 457-468
    • Fleischmann, R.1    Mysler, E.2    Hall, S.3
  • 78
    • 84877275257 scopus 로고    scopus 로고
    • Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): A randomised, double-blind, controlled phase 4 trial
    • [published correction appears in Lancet. 2013;381(9877):1540]..;():. doi: 23515142
    • Gabay C, Emery P, van Vollenhoven R,; ADACTA Study Investigators. Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial [published correction appears in Lancet. 2013;381(9877):1540]. Lancet. 2013; 381 (9877): 1541-1550. doi: 10.1016/S0140-6736(13)60250-0 23515142
    • (2013) Lancet , vol.381 , Issue.9877 , pp. 1541-1550
    • Gabay, C.1    Emery, P.2    Van Vollenhoven, R.3
  • 79
    • 85019144284 scopus 로고    scopus 로고
    • Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): A randomised, double-blind, parallel-group phase III trial
    • 27856432
    • Burmester GR, Lin Y, Patel R, Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial. Ann Rheum Dis. 2017; 76 (5): 840-847. doi: 10.1136/annrheumdis-2016-210310 27856432
    • (2017) Ann Rheum Dis , vol.76 , Issue.5 , pp. 840-847
    • Burmester, G.R.1    Lin, Y.2    Patel, R.3
  • 80
    • 84964773927 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • 10055 27156434
    • Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016; 388 (10055): 2023-2038. doi: 10.1016/S0140-6736(16)30173-8 27156434
    • (2016) Lancet , vol.388 , pp. 2023-2038
    • Smolen, J.S.1    Aletaha, D.2    McInnes, I.B.3
  • 81
    • 85013393351 scopus 로고    scopus 로고
    • Baricitinib versus placebo or adalimumab in rheumatoid arthritis
    • 28199814
    • Taylor PC, Keystone EC, van der Heijde D, Baricitinib versus placebo or adalimumab in rheumatoid arthritis. N Engl J Med. 2017; 376 (7): 652-662. doi: 10.1056/NEJMoa1608345 28199814
    • (2017) N Engl J Med , vol.376 , Issue.7 , pp. 652-662
    • Taylor, P.C.1    Keystone, E.C.2    Van Der Heijde, D.3
  • 82
    • 85048340669 scopus 로고    scopus 로고
    • Safety and efficacy of upadacitinib in patients with active rheumatoid arthritis refractory to biologic disease-modifying anti-rheumatic drugs (SELECT-BEYOND): A double-blind, randomised controlled phase 3 trial
    • 10139 29908670
    • Genovese MC, Fleischmann R, Combe B, Safety and efficacy of upadacitinib in patients with active rheumatoid arthritis refractory to biologic disease-modifying anti-rheumatic drugs (SELECT-BEYOND): a double-blind, randomised controlled phase 3 trial. Lancet. 2018; 391 (10139): 2513-2524. doi: 10.1016/S0140-6736(18)31116-4 29908670
    • (2018) Lancet , vol.391 , pp. 2513-2524
    • Genovese, M.C.1    Fleischmann, R.2    Combe, B.3
  • 83
    • 85048339448 scopus 로고    scopus 로고
    • Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): A randomised, double-blind, placebo-controlled phase 3 trial
    • 10139 29908669
    • Burmester GR, Kremer JM, Van den Bosch F, Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2018; 391 (10139): 2503-2512. doi: 10.1016/S0140-6736(18)31115-2 29908669
    • (2018) Lancet , vol.391 , pp. 2503-2512
    • Burmester, G.R.1    Kremer, J.M.2    Van Den Bosch, F.3
  • 84
    • 85054773546 scopus 로고    scopus 로고
    • Upadacitinib as monotherapy: A phase 3 randomised controlled double-blind study in patients with active rheumatoid arthritis and inadequate response to methotrexate
    • [abstract]..;().
    • Smolen JS, Cohen S, Emery P, Upadacitinib as monotherapy: a phase 3 randomised controlled double-blind study in patients with active rheumatoid arthritis and inadequate response to methotrexate [abstract]. Ann Rheum Dis. 2018; 77 (suppl): A67.
    • (2018) Ann Rheum Dis , vol.77 , pp. A67
    • Smolen, J.S.1    Cohen, S.2    Emery, P.3
  • 85
    • 85007236113 scopus 로고    scopus 로고
    • Filgotinib (GLPG0634/GS-6034), an oral JAK1 selective inhibitor, is effective in combination with methotrexate (MTX) in patients with active rheumatoid arthritis and insufficient response to MTX: Results from a randomised, dose-finding study (DARWIN 1)
    • 27993829
    • Westhovens R, Taylor PC, Alten R, Filgotinib (GLPG0634/GS-6034), an oral JAK1 selective inhibitor, is effective in combination with methotrexate (MTX) in patients with active rheumatoid arthritis and insufficient response to MTX: results from a randomised, dose-finding study (DARWIN 1). Ann Rheum Dis. 2017; 76 (6): 998-1008. doi: 10.1136/annrheumdis-2016-210104 27993829
    • (2017) Ann Rheum Dis , vol.76 , Issue.6 , pp. 998-1008
    • Westhovens, R.1    Taylor, P.C.2    Alten, R.3
  • 86
    • 84929023302 scopus 로고    scopus 로고
    • Rheumatoid arthritis therapy reappraisal: Strategies, opportunities and challenges
    • 25687177
    • Smolen JS, Aletaha D. Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges. Nat Rev Rheumatol. 2015; 11 (5): 276-289. doi: 10.1038/nrrheum.2015.8 25687177
    • (2015) Nat Rev Rheumatol , vol.11 , Issue.5 , pp. 276-289
    • Smolen, J.S.1    Aletaha, D.2
  • 87
    • 84897019337 scopus 로고    scopus 로고
    • Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium
    • 24449571
    • Ducreux J, Durez P, Galant C, Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014; 66 (1): 15-23. doi: 10.1002/art.38202 24449571
    • (2014) Arthritis Rheumatol , vol.66 , Issue.1 , pp. 15-23
    • Ducreux, J.1    Durez, P.2    Galant, C.3
  • 88
    • 17244364098 scopus 로고    scopus 로고
    • Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: A detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study
    • 15818697
    • Smolen JS, Han C, Bala M,; ATTRACT Study Group. Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: a detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study. Arthritis Rheum. 2005; 52 (4): 1020-1030. doi: 10.1002/art.20982 15818697
    • (2005) Arthritis Rheum , vol.52 , Issue.4 , pp. 1020-1030
    • Smolen, J.S.1    Han, C.2    Bala, M.3
  • 89
    • 84859517375 scopus 로고    scopus 로고
    • Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: Disassociation of the link between inflammation and destruction
    • 22121130
    • Smolen JS, Avila JC, Aletaha D. Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: disassociation of the link between inflammation and destruction. Ann Rheum Dis. 2012; 71 (5): 687-693. doi: 10.1136/annrheumdis-2011-200395 22121130
    • (2012) Ann Rheum Dis , vol.71 , Issue.5 , pp. 687-693
    • Smolen, J.S.1    Avila, J.C.2    Aletaha, D.3
  • 90
    • 84874422827 scopus 로고    scopus 로고
    • Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis
    • 23280418
    • Binder NB, Puchner A, Niederreiter B, Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis. Arthritis Rheum. 2013; 65 (3): 608-617. doi: 10.1002/art.37797 23280418
    • (2013) Arthritis Rheum , vol.65 , Issue.3 , pp. 608-617
    • Binder, N.B.1    Puchner, A.2    Niederreiter, B.3
  • 91
    • 85040782667 scopus 로고    scopus 로고
    • Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: Results of the PRESERVE trial
    • 29338762
    • Smolen JS, Szumski A, Koenig AS, Jones TV, Marshall L. Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: results of the PRESERVE trial. Arthritis Res Ther. 2018; 20 (1): 8. doi: 10.1186/s13075-017-1484-9 29338762
    • (2018) Arthritis Res Ther , vol.20 , Issue.1 , pp. 8
    • Smolen, J.S.1    Szumski, A.2    Koenig, A.S.3    Jones, T.V.4    Marshall, L.5
  • 92
    • 84874983369 scopus 로고    scopus 로고
    • Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): A randomised controlled trial
    • 23332236
    • Smolen JS, Nash P, Durez P, Maintenance, reduction, or withdrawal of etanercept after treatment with etanercept and methotrexate in patients with moderate rheumatoid arthritis (PRESERVE): a randomised controlled trial. Lancet. 2013; 381 (9870): 918-929. doi: 10.1016/S0140-6736(12)61811-X 23332236
    • (2013) Lancet , vol.381 , Issue.9870 , pp. 918-929
    • Smolen, J.S.1    Nash, P.2    Durez, P.3
  • 93
    • 84921295252 scopus 로고    scopus 로고
    • Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study
    • 24288014
    • Tanaka Y, Hirata S, Kubo S, Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study. Ann Rheum Dis. 2015; 74 (2): 389-395. doi: 10.1136/annrheumdis-2013-204016 24288014
    • (2015) Ann Rheum Dis , vol.74 , Issue.2 , pp. 389-395
    • Tanaka, Y.1    Hirata, S.2    Kubo, S.3
  • 94
    • 85047417783 scopus 로고    scopus 로고
    • Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
    • 29529307
    • Rutherford AI, Patarata E, Subesinghe S, Hyrich KL, Galloway JB. Opportunistic infections in rheumatoid arthritis patients exposed to biologic therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Rheumatology (Oxford). 2018; 57 (6): 997-1001. doi: 10.1093/rheumatology/key023 29529307
    • (2018) Rheumatology (Oxford) , vol.57 , Issue.6 , pp. 997-1001
    • Rutherford, A.I.1    Patarata, E.2    Subesinghe, S.3    Hyrich, K.L.4    Galloway, J.B.5
  • 95
    • 85011115927 scopus 로고    scopus 로고
    • A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate
    • 28087506
    • Smolen JS, Agarwal SK, Ilivanova E, A randomised phase II study evaluating the efficacy and safety of subcutaneously administered ustekinumab and guselkumab in patients with active rheumatoid arthritis despite treatment with methotrexate. Ann Rheum Dis. 2017; 76 (5): 831-839. doi: 10.1136/annrheumdis-2016-209831 28087506
    • (2017) Ann Rheum Dis , vol.76 , Issue.5 , pp. 831-839
    • Smolen, J.S.1    Agarwal, S.K.2    Ilivanova, E.3
  • 96
    • 0029115051 scopus 로고
    • A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis
    • 7639806
    • van der Lubbe PA, Dijkmans BA, Markusse HM, Nässander U, Breedveld FC. A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis. Arthritis Rheum. 1995; 38 (8): 1097-1106. doi: 10.1002/art.1780380812 7639806
    • (1995) Arthritis Rheum , vol.38 , Issue.8 , pp. 1097-1106
    • Van Der Lubbe, P.A.1    Dijkmans, B.A.2    Markusse, H.M.3    Nässander, U.4    Breedveld, F.C.5
  • 97
    • 84877603562 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in patients with rheumatoid arthritis: A phase II, dose-finding, double-blind, randomised, placebo controlled study
    • 22730366
    • Genovese MC, Durez P, Richards HB, Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study. Ann Rheum Dis. 2013; 72 (6): 863-869. doi: 10.1136/annrheumdis-2012-201601 22730366
    • (2013) Ann Rheum Dis , vol.72 , Issue.6 , pp. 863-869
    • Genovese, M.C.1    Durez, P.2    Richards, H.B.3
  • 98
    • 79955563297 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis
    • 21285160
    • Genovese MC, Cohen SB, Wofsy D, A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis. J Rheumatol. 2011; 38 (5): 846-854. doi: 10.3899/jrheum.100602 21285160
    • (2011) J Rheumatol , vol.38 , Issue.5 , pp. 846-854
    • Genovese, M.C.1    Cohen, S.B.2    Wofsy, D.3
  • 100
    • 84921403951 scopus 로고    scopus 로고
    • Time trends in disease activity, response and remission rates in rheumatoid arthritis during the past decade: Results from the NOR-DMARD study 2000-2010
    • 24285493
    • Aga AB, Lie E, Uhlig T, Time trends in disease activity, response and remission rates in rheumatoid arthritis during the past decade: results from the NOR-DMARD study 2000-2010. Ann Rheum Dis. 2015; 74 (2): 381-388. doi: 10.1136/annrheumdis-2013-204020 24285493
    • (2015) Ann Rheum Dis , vol.74 , Issue.2 , pp. 381-388
    • Aga, A.B.1    Lie, E.2    Uhlig, T.3
  • 101
    • 84921296424 scopus 로고    scopus 로고
    • Mortality in rheumatoid arthritis: The impact of disease activity, treatment with glucocorticoids, TNFα inhibitors and rituximab
    • 24291654
    • Listing J, Kekow J, Manger B, Mortality in rheumatoid arthritis: the impact of disease activity, treatment with glucocorticoids, TNFα inhibitors and rituximab. Ann Rheum Dis. 2015; 74 (2): 415-421. doi: 10.1136/annrheumdis-2013-204021 24291654
    • (2015) Ann Rheum Dis , vol.74 , Issue.2 , pp. 415-421
    • Listing, J.1    Kekow, J.2    Manger, B.3
  • 102
    • 84889688016 scopus 로고    scopus 로고
    • Inequities in access to biologic and synthetic DMARDs across 46 European countries
    • 23467636
    • Putrik P, Ramiro S, Kvien TK,; Working Group "Equity in Access to Treatment of Rheumatoid Arthritis in Europe." Inequities in access to biologic and synthetic DMARDs across 46 European countries. Ann Rheum Dis. 2014; 73 (1): 198-206. doi: 10.1136/annrheumdis-2012-202603 23467636
    • (2014) Ann Rheum Dis , vol.73 , Issue.1 , pp. 198-206
    • Putrik, P.1    Ramiro, S.2    Kvien, T.K.3
  • 103
    • 85018303509 scopus 로고    scopus 로고
    • Future therapeutic targets in rheumatoid arthritis?
    • 28451787
    • Cheung TT, McInnes IB. Future therapeutic targets in rheumatoid arthritis? Semin Immunopathol. 2017; 39 (4): 487-500. doi: 10.1007/s00281-017-0623-3 28451787
    • (2017) Semin Immunopathol , vol.39 , Issue.4 , pp. 487-500
    • Cheung, T.T.1    McInnes, I.B.2
  • 104
    • 85044627852 scopus 로고    scopus 로고
    • Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: Long-term safety and efficacy in patients with rheumatoid arthritis
    • 29361199
    • Burmester GR, McInnes IB, Kremer JM, Mavrilimumab, a fully human granulocyte-macrophage colony-stimulating factor receptor α monoclonal antibody: long-term safety and efficacy in patients with rheumatoid arthritis. Arthritis Rheumatol. 2018; 70 (5): 679-689. doi: 10.1002/art.40420 29361199
    • (2018) Arthritis Rheumatol , vol.70 , Issue.5 , pp. 679-689
    • Burmester, G.R.1    McInnes, I.B.2    Kremer, J.M.3
  • 105
    • 84940181646 scopus 로고    scopus 로고
    • Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis
    • 26307404
    • Blüml S, Sahin E, Saferding V, Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis. Arthritis Res Ther. 2015; 17: 230. doi: 10.1186/s13075-015-0742-y 26307404
    • (2015) Arthritis Res Ther , vol.17 , pp. 230
    • Blüml, S.1    Sahin, E.2    Saferding, V.3
  • 106
    • 85028377533 scopus 로고    scopus 로고
    • The unmet need in rheumatology: Reports from the targeted therapies meeting 2017
    • 28811201
    • Winthrop KL, Strand V, van der Heijde D, The unmet need in rheumatology: reports from the targeted therapies meeting 2017. Clin Immunol. 2018; 186: 87-93. doi: 10.1016/j.clim.2017.08.009 28811201
    • (2018) Clin Immunol , vol.186 , pp. 87-93
    • Winthrop, K.L.1    Strand, V.2    Van Der Heijde, D.3
  • 107
    • 84859487325 scopus 로고    scopus 로고
    • EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: Report from the Study Group for Risk Factors for Rheumatoid Arthritis
    • 22387728
    • Gerlag DM, Raza K, van Baarsen LG, EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis. Ann Rheum Dis. 2012; 71 (5): 638-641. doi: 10.1136/annrheumdis-2011-200990 22387728
    • (2012) Ann Rheum Dis , vol.71 , Issue.5 , pp. 638-641
    • Gerlag, D.M.1    Raza, K.2    Van Baarsen, L.G.3
  • 108
    • 85017543997 scopus 로고    scopus 로고
    • Prevention of rheumatoid arthritis: Now is the time, but how to proceed?
    • 28217918
    • Deane KD, Striebich CC, Holers VM. Prevention of rheumatoid arthritis: now is the time, but how to proceed? Arthritis Rheumatol. 2017; 69 (5): 873-877. doi: 10.1002/art.40061 28217918
    • (2017) Arthritis Rheumatol , vol.69 , Issue.5 , pp. 873-877
    • Deane, K.D.1    Striebich, C.C.2    Holers, V.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.