Erratum: The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity (Immunity (2018) 49(2) (353–362.e5), (S1074761318303303), (10.1016/j.immuni.2018.07.010));The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

Immunity

Volumn 49, Issue 2, 2018, Pages 353-362.e5

  Metidji, Amina ^a   Omenetti, Sara ^a   Crotta, Stefania ^a   Li, Ying ^a   Nye, Emma ^a   Ross, Ellie ^b   Li, Vivian ^a   Maradana, Muralidhara R ^a   Schiering, Chris ^a,c   Stockinger, Brigitta ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

AHR; colon cancer; crypt stem cell; diet; goblet cells; gut barrier; IBD; indole 3 carbinol; inflammation; intestinal epithelial cell; Wnt catenin

Indexed keywords

3 INDOLEMETHANOL; AROMATIC HYDROCARBON RECEPTOR; AXIN2 PROTEIN; BETA 2 MICROGLOBULIN; BETA CATENIN; CALGRANULIN B; CAR4 PROTEIN; CELL MARKER; EPHRIN RECEPTOR B2; EPITHELIAL CELL ADHESION MOLECULE; INTERLEUKIN 22; INTERLEUKIN 6; MUCIN 2; MYC PROTEIN; REG3G PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RNF43; TRANSCRIPTION FACTOR ZNRF3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VILLIN; WNT PROTEIN; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; RNF43 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE; ZNRF3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; CITROBACTER RODENTIUM; CITROBACTER RODENTIUM INFECTION; COLORECTAL CANCER; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENTEROBACTERIACEAE INFECTION; GENE DELETION; HOMEOSTASIS; INFLAMMATION; INTESTINAL STEM CELL; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; STEM CELL NICHE; STEM CELL SELF-RENEWAL; TRANSCRIPTION REGULATION; WNT SIGNALING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; CYTOLOGY; EPITHELIUM CELL; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; STEM CELL; TIGHT JUNCTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOGENESIS; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CITROBACTER RODENTIUM; ENTEROBACTERIACEAE INFECTIONS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, ARYL HYDROCARBON; STEM CELLS; TIGHT JUNCTIONS; UBIQUITIN-PROTEIN LIGASES; WNT SIGNALING PATHWAY;

EID: 85053900152     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2019.05.024     Document Type: Erratum

References (45)

1. Andersson, P., McGuire, J., Rubio, C., Gradin, K., Whitelaw, M.L., Pettersson, S., Hanberg, A., Poellinger, L., A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc. Natl. Acad. Sci. USA 99 (2002), 9990–9995.
2. Barker, N., van Es, J.H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P.J., Clevers, H., Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449 (2007), 1003–1007.
3. Beyaz, S., Mana, M.D., Roper, J., Kedrin, D., Saadatpour, A., Hong, S.J., Bauer-Rowe, K.E., Xifaras, M.E., Akkad, A., Arias, E., et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature 531 (2016), 53–58.
4. Bjeldanes, L.F., Kim, J.Y., Grose, K.R., Bartholomew, J.C., Bradfield, C.A., Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. USA 88 (1991), 9543–9547.
5. Borten, M.A., Bajikar, S.S., Sasaki, N., Clevers, H., Janes, K.A., Automated brightfield morphometry of 3D organoid populations by OrganoSeg. Sci. Rep., 8, 2018, 5319.
6. Denison, M.S., Nagy, S.R., Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol. 43 (2003), 309–334.
7. Díaz-Díaz, C.J., Ronnekleiv-Kelly, S.M., Nukaya, M., Geiger, P.G., Balbo, S., Dator, R., Megna, B.W., Carney, P.R., Bradfield, C.A., Kennedy, G.D., The aryl hydrocarbon receptor is a repressor of inflammation-associated colorectal tumorigenesis in mouse. Ann. Surg. 264 (2016), 429–436.
8. Furumatsu, K., Nishiumi, S., Kawano, Y., Ooi, M., Yoshie, T., Shiomi, Y., Kutsumi, H., Ashida, H., Fujii-Kuriyama, Y., Azuma, T., Yoshida, M., A role of the aryl hydrocarbon receptor in attenuation of colitis. Dig. Dis. Sci. 56 (2011), 2532–2544.
9. Hao, H.X., Xie, Y., Zhang, Y., Charlat, O., Oster, E., Avello, M., Lei, H., Mickanin, C., Liu, D., Ruffner, H., et al. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 485 (2012), 195–200.
10. Hubbard, T.D., Murray, I.A., Bisson, W.H., Lahoti, T.S., Gowda, K., Amin, S.G., Patterson, A.D., Perdew, G.H., Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles. Sci. Rep., 5, 2015, 12689.
11. Jiang, R., Wang, H., Deng, L., Hou, J., Shi, R., Yao, M., Gao, Y., Yao, A., Wang, X., Yu, L., Sun, B., IL-22 is related to development of human colon cancer by activation of STAT3. BMC Cancer, 13, 2013, 59.
12. Kawajiri, K., Kobayashi, Y., Ohtake, F., Ikuta, T., Matsushima, Y., Mimura, J., Pettersson, S., Pollenz, R.S., Sakaki, T., Hirokawa, T., et al. Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc. Natl. Acad. Sci. USA 106 (2009), 13481–13486.
13. Kim, Y.S., Milner, J.A., Targets for indole-3-carbinol in cancer prevention. J. Nutr. Biochem. 16 (2005), 65–73.
14. Kiss, E.A., Vonarbourg, C., Kopfmann, S., Hobeika, E., Finke, D., Esser, C., Diefenbach, A., Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334 (2011), 1561–1565.
15. Kleman, M.I., Poellinger, L., Gustafsson, J.A., Regulation of human dioxin receptor function by indolocarbazoles, receptor ligands of dietary origin. J. Biol. Chem. 269 (1994), 5137–5144.
16. Koo, B.K., Spit, M., Jordens, I., Low, T.Y., Stange, D.E., van de Wetering, M., van Es, J.H., Mohammed, S., Heck, A.J., Maurice, M.M., Clevers, H., Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature 488 (2012), 665–669.
17. Koo, B.K., van Es, J.H., van den Born, M., Clevers, H., Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia. Proc. Natl. Acad. Sci. USA 112 (2015), 7548–7550.
18. Kryczek, I., Lin, Y., Nagarsheth, N., Peng, D., Zhao, L., Zhao, E., Vatan, L., Szeliga, W., Dou, Y., Owens, S., et al. IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L. Immunity 40 (2014), 772–784.
19. Lamas, B., Richard, M.L., Leducq, V., Pham, H.P., Michel, M.L., Da Costa, G., Bridonneau, C., Jegou, S., Hoffmann, T.W., Natividad, J.M., et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat. Med. 22 (2016), 598–605.
20. Lee, J.S., Cella, M., McDonald, K.G., Garlanda, C., Kennedy, G.D., Nukaya, M., Mantovani, A., Kopan, R., Bradfield, C.A., Newberry, R.D., Colonna, M., AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nat. Immunol. 13 (2011), 144–151.
21. Li, Y., Innocentin, S., Withers, D.R., Roberts, N.A., Gallagher, A.R., Grigorieva, E.F., Wilhelm, C., Veldhoen, M., Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell 147 (2011), 629–640.
22. Liu, J.Z., van Sommeren, S., Huang, H., Ng, S.C., Alberts, R., Takahashi, A., Ripke, S., Lee, J.C., Jostins, L., Shah, T., et al. International Multiple Sclerosis Genetics Consortium, International IBD Genetics Consortium. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat. Genet. 47 (2015), 979–986.
23. Luecke-Johansson, S., Gralla, M., Rundqvist, H., Ho, J.C., Johnson, R.S., Gradin, K., Poellinger, L., A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase. Mol. Cell. Biol., 37, 2017, 37.
24. Mayne, S.T., Playdon, M.C., Rock, C.L., Diet, nutrition, and cancer: past, present and future. Nat. Rev. Clin. Oncol. 13 (2016), 504–515.
25. McMillan, B.J., Bradfield, C.A., The aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems. Mol. Pharmacol. 72 (2007), 487–498.
26. Mitchell, K.A., Elferink, C.J., Timing is everything: consequences of transient and sustained AhR activity. Biochem. Pharmacol. 77 (2009), 947–956.
27. Moura-Alves, P., Faé K., Houthuys, E., Dorhoi, A., Kreuchwig, A., Furkert, J., Barison, N., Diehl, A., Munder, A., Constant, P., et al. AhR sensing of bacterial pigments regulates antibacterial defence. Nature 512 (2014), 387–392.
28. Novellasdemunt, L., Antas, P., Li, V.S., Targeting Wnt signaling in colorectal cancer. A review in the theme: cell signaling: proteins, pathways and mechanisms. Am. J. Physiol. Cell Physiol. 309 (2015), C511–C521.
29. Ohtake, F., Baba, A., Takada, I., Okada, M., Iwasaki, K., Miki, H., Takahashi, S., Kouzmenko, A., Nohara, K., Chiba, T., et al. Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature 446 (2007), 562–566.
30. Papapietro, O., Teatero, S., Thanabalasuriar, A., Yuki, K.E., Diez, E., Zhu, L., Kang, E., Dhillon, S., Muise, A.M., Durocher, Y., et al. R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea. Nat. Commun., 4, 2013, 1898.
31. Potter, J.D., Steinmetz, K., Vegetables, fruit and phytoestrogens as preventive agents. IARC Sci. Publ. 139 (1996), 61–90.
32. Qiu, J., Heller, J.J., Guo, X., Chen, Z.M., Fish, K., Fu, Y.X., Zhou, L., The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells. Immunity 36 (2012), 92–104.
33. Sato, T., Clevers, H., Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340 (2013), 1190–1194.
34. Sato, T., Vries, R.G., Snippert, H.J., van de Wetering, M., Barker, N., Stange, D.E., van Es, J.H., Abo, A., Kujala, P., Peters, P.J., Clevers, H., Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459 (2009), 262–265.
35. Schäfer, M., Werner, S., Cancer as an overhealing wound: an old hypothesis revisited. Nat. Rev. Mol. Cell Biol. 9 (2008), 628–638.
36. Schiering, C., Wincent, E., Metidji, A., Iseppon, A., Li, Y., Potocnik, A.J., Omenetti, S., Henderson, C.J., Wolf, C.R., Nebert, D.W., Stockinger, B., Feedback control of AHR signalling regulates intestinal immunity. Nature 542 (2017), 242–245.
37. Schmidt, J.V., Bradfield, C.A., Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 12 (1996), 55–89.
38. Terry, P., Giovannucci, E., Michels, K.B., Bergkvist, L., Hansen, H., Holmberg, L., Wolk, A., Fruit, vegetables, dietary fiber, and risk of colorectal cancer. J. Natl. Cancer Inst. 93 (2001), 525–533.
39. Tsukiyama, T., Fukui, A., Terai, S., Fujioka, Y., Shinada, K., Takahashi, H., Yamaguchi, T.P., Ohba, Y., Hatakeyama, S., Molecular role of RNF43 in canonical and noncanonical Wnt signaling. Mol. Cell. Biol. 35 (2015), 2007–2023.
40. Vallance, B.A., Deng, W., Jacobson, K., Finlay, B.B., Host susceptibility to the attaching and effacing bacterial pathogen Citrobacter rodentium. Infect. Immun. 71 (2003), 3443–3453.
41. Walisser, J.A., Glover, E., Pande, K., Liss, A.L., Bradfield, C.A., Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types. Proc. Natl. Acad. Sci. USA 102 (2005), 17858–17863.
42. Weng, J.R., Tsai, C.H., Kulp, S.K., Chen, C.S., Indole-3-carbinol as a chemopreventive and anti-cancer agent. Cancer Lett. 262 (2008), 153–163.
43. West, N.R., McCuaig, S., Franchini, F., Powrie, F., Emerging cytokine networks in colorectal cancer. Nat. Rev. Immunol. 15 (2015), 615–629.
44. Zelante, T., Iannitti, R.G., Cunha, C., De Luca, A., Giovannini, G., Pieraccini, G., Zecchi, R., D'Angelo, C., Massi-Benedetti, C., Fallarino, F., et al. Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity 39 (2013), 372–385.
45. Zitvogel, L., Pietrocola, F., Kroemer, G., Nutrition, inflammation and cancer. Nat. Immunol. 18 (2017), 843–850.